Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01067:Zfp971'

50398

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp971

Ensembl Gene

ENSMUSG00000074519

Gene Name

zinc finger protein 971

Synonyms

Etohi1

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.094) question?

Stock #

IGL01067

Quality Score

Status

Chromosome

Chromosomal Location

177665077-177675815 bp(+) (GRCm39)

Type of Mutation

critical splice donor site (1 bp from exon)

DNA Base Change (assembly)

G to A at 177665175 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000104554 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000108925] [ENSMUST00000108926]

AlphaFold

A2BFG8

Predicted Effect

probably null
Transcript: ENSMUST00000108925

SMART Domains

Protein: ENSMUSP00000104553
Gene: ENSMUSG00000074519

Domain	Start	End	E-Value	Type
KRAB	4	64	1.2e-12	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000108926

SMART Domains

Protein: ENSMUSP00000104554
Gene: ENSMUSG00000074519

Domain	Start	End	E-Value	Type
KRAB	4	66	1.6e-13	SMART
ZnF_C2H2	78	97	1.38e2	SMART
ZnF_C2H2	103	125	4.38e1	SMART
ZnF_C2H2	131	153	1.92e-2	SMART
ZnF_C2H2	159	181	4.79e-3	SMART
ZnF_C2H2	187	209	2.36e-2	SMART
ZnF_C2H2	215	237	2.36e-2	SMART
ZnF_C2H2	243	265	3.69e-4	SMART
ZnF_C2H2	271	293	4.87e-4	SMART
ZnF_C2H2	299	321	4.4e-2	SMART
ZnF_C2H2	327	349	4.61e-5	SMART
ZnF_C2H2	355	377	4.94e-5	SMART
ZnF_C2H2	383	405	3.21e-4	SMART
ZnF_C2H2	411	433	4.47e-3	SMART
ZnF_C2H2	439	461	5.99e-4	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000181241

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 50 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110038F14Rik	G	A	15: 76,834,475 (GRCm39)	V124I	probably damaging	Het
A330008L17Rik	T	C	8: 100,148,586 (GRCm39)		noncoding transcript	Het
Acp4	C	T	7: 43,902,876 (GRCm39)	V331I	probably benign	Het
Aen	G	A	7: 78,557,050 (GRCm39)	M299I	probably damaging	Het
Alg6	T	C	4: 99,629,807 (GRCm39)	V128A	probably benign	Het
Ank3	A	G	10: 69,686,026 (GRCm39)	K280E	probably damaging	Het
Bfar	T	C	16: 13,503,105 (GRCm39)	C36R	probably damaging	Het
Car14	A	G	3: 95,806,128 (GRCm39)	I311T	probably damaging	Het
Cd300c	T	C	11: 114,851,253 (GRCm39)		probably benign	Het
Cfap100	T	A	6: 90,383,096 (GRCm39)	E513V	probably damaging	Het
Clip1	C	A	5: 123,768,867 (GRCm39)	K612N	probably damaging	Het
Depdc5	A	G	5: 33,056,411 (GRCm39)		probably null	Het
Dock3	A	T	9: 106,959,572 (GRCm39)		probably null	Het
Dph6	A	T	2: 114,478,290 (GRCm39)	M17K	probably damaging	Het
Enkur	T	C	2: 21,194,042 (GRCm39)	Q177R	probably benign	Het
Faap100	T	C	11: 120,262,958 (GRCm39)	H800R	probably damaging	Het
Fastkd2	T	G	1: 63,776,930 (GRCm39)		probably benign	Het
Fcgr2b	A	T	1: 170,795,622 (GRCm39)	N102K	possibly damaging	Het
Fezf1	C	T	6: 23,247,842 (GRCm39)	V78I	possibly damaging	Het
Fmn2	A	T	1: 174,330,885 (GRCm39)	D425V	unknown	Het
Fnta	G	A	8: 26,497,229 (GRCm39)	Q207*	probably null	Het
Fpr3	T	A	17: 18,190,828 (GRCm39)	V33D	probably benign	Het
Fshr	C	T	17: 89,292,821 (GRCm39)	C619Y	possibly damaging	Het
Gbp3	T	C	3: 142,272,358 (GRCm39)		probably null	Het
Gjb2	A	G	14: 57,337,629 (GRCm39)	V193A	possibly damaging	Het
Il4ra	A	G	7: 125,174,333 (GRCm39)	T292A	probably benign	Het
Lama5	A	G	2: 179,818,336 (GRCm39)		probably benign	Het
Marveld3	G	T	8: 110,688,596 (GRCm39)	D48E	possibly damaging	Het
Meox1	A	T	11: 101,784,599 (GRCm39)	I78N	probably benign	Het
Ncor1	A	T	11: 62,283,354 (GRCm39)	H444Q	probably damaging	Het
Ndst3	T	C	3: 123,340,466 (GRCm39)	Q784R	probably damaging	Het
Or10ag2	A	G	2: 87,248,714 (GRCm39)	I107M	probably benign	Het
Or4k44	T	A	2: 111,368,359 (GRCm39)	I92F	probably damaging	Het
Pld5	A	T	1: 176,102,445 (GRCm39)		probably benign	Het
Plk1	G	A	7: 121,768,148 (GRCm39)	R456H	probably damaging	Het
Polr2a	T	A	11: 69,638,840 (GRCm39)	I65F	possibly damaging	Het
Ptprd	T	A	4: 75,977,922 (GRCm39)	I196F	probably damaging	Het
Qsox2	T	C	2: 26,118,408 (GRCm39)	N121S	probably damaging	Het
Reln	A	G	5: 22,184,664 (GRCm39)	L1617S	probably damaging	Het
Rragc	T	C	4: 123,823,761 (GRCm39)	F345L	probably benign	Het
Sass6	A	T	3: 116,407,605 (GRCm39)	E240D	possibly damaging	Het
Shcbp1l	A	C	1: 153,311,770 (GRCm39)	S308R	possibly damaging	Het
Slc1a5	T	A	7: 16,520,804 (GRCm39)	C224*	probably null	Het
Slc27a5	T	C	7: 12,722,999 (GRCm39)	E567G	probably damaging	Het
Synj2	T	A	17: 6,088,201 (GRCm39)	N1417K	possibly damaging	Het
Tbc1d9	A	G	8: 83,960,791 (GRCm39)	T214A	probably damaging	Het
Tjp3	C	A	10: 81,109,699 (GRCm39)	V835L	probably benign	Het
Trpc4	C	A	3: 54,129,983 (GRCm39)	Q250K	probably benign	Het
Ttn	A	T	2: 76,575,506 (GRCm39)	I25129N	probably damaging	Het
Ube4a	T	A	9: 44,856,163 (GRCm39)	Y523F	probably damaging	Het

Other mutations in Zfp971

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R1108:Zfp971	UTSW	2	177,675,463 (GRCm39)	missense	probably damaging	1.00
R1759:Zfp971	UTSW	2	177,675,722 (GRCm39)	missense	probably damaging	0.99
R2183:Zfp971	UTSW	2	177,675,533 (GRCm39)	missense	probably damaging	1.00
R2343:Zfp971	UTSW	2	177,674,787 (GRCm39)	missense	possibly damaging	0.84
R4873:Zfp971	UTSW	2	177,674,940 (GRCm39)	missense	probably benign	0.24
R4875:Zfp971	UTSW	2	177,674,940 (GRCm39)	missense	probably benign	0.24
R5263:Zfp971	UTSW	2	177,675,555 (GRCm39)	missense	probably damaging	1.00
R5396:Zfp971	UTSW	2	177,675,526 (GRCm39)	missense	probably damaging	1.00
R6150:Zfp971	UTSW	2	177,675,247 (GRCm39)	missense	probably benign	0.26
R6693:Zfp971	UTSW	2	177,675,224 (GRCm39)	missense	probably benign	0.01
R6811:Zfp971	UTSW	2	177,675,674 (GRCm39)	missense	possibly damaging	0.62
R7427:Zfp971	UTSW	2	177,674,967 (GRCm39)	missense	probably damaging	1.00
R7428:Zfp971	UTSW	2	177,674,967 (GRCm39)	missense	probably damaging	1.00
R7594:Zfp971	UTSW	2	177,675,793 (GRCm39)	missense	possibly damaging	0.47
R7790:Zfp971	UTSW	2	177,675,292 (GRCm39)	missense	probably damaging	0.96
R7796:Zfp971	UTSW	2	177,673,403 (GRCm39)	missense	probably benign	0.00
R7934:Zfp971	UTSW	2	177,675,173 (GRCm39)	missense	probably benign
R7990:Zfp971	UTSW	2	177,675,361 (GRCm39)	missense	probably damaging	1.00
R8671:Zfp971	UTSW	2	177,675,730 (GRCm39)	missense	probably damaging	1.00
R9181:Zfp971	UTSW	2	177,674,736 (GRCm39)	missense	probably damaging	1.00
R9575:Zfp971	UTSW	2	177,675,303 (GRCm39)	missense	probably damaging	0.99
R9629:Zfp971	UTSW	2	177,675,417 (GRCm39)	missense	probably damaging	0.96

Posted On

2013-06-21