Incidental Mutation 'IGL01092:Ppp1r26'
ID50478
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ppp1r26
Ensembl Gene ENSMUSG00000035829
Gene Nameprotein phosphatase 1, regulatory subunit 26
SynonymsLOC241289
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01092
Quality Score
Status
Chromosome2
Chromosomal Location28446800-28455508 bp(+) (GRCm38)
Type of Mutationutr 3 prime
DNA Base Change (assembly) C to T at 28453860 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000139546 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000040324] [ENSMUST00000189694]
Predicted Effect probably benign
Transcript: ENSMUST00000040324
SMART Domains Protein: ENSMUSP00000042173
Gene: ENSMUSG00000035829

DomainStartEndE-ValueType
Pfam:PPP1R26_N 1 812 N/A PFAM
low complexity region 901 913 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000128199
Predicted Effect noncoding transcript
Transcript: ENSMUST00000150362
Predicted Effect noncoding transcript
Transcript: ENSMUST00000154081
Predicted Effect probably benign
Transcript: ENSMUST00000189694
SMART Domains Protein: ENSMUSP00000139546
Gene: ENSMUSG00000035829

DomainStartEndE-ValueType
low complexity region 122 132 N/A INTRINSIC
low complexity region 487 504 N/A INTRINSIC
low complexity region 515 536 N/A INTRINSIC
low complexity region 551 559 N/A INTRINSIC
low complexity region 636 654 N/A INTRINSIC
low complexity region 766 780 N/A INTRINSIC
low complexity region 901 913 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 35 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Arhgap33 T C 7: 30,529,946 R335G probably damaging Het
Atad2b C T 12: 5,017,987 S995L probably damaging Het
Atrn A T 2: 130,947,636 R340* probably null Het
Ccdc83 A T 7: 90,247,105 D85E probably benign Het
Chd2 A T 7: 73,441,686 H1602Q possibly damaging Het
Cog2 A G 8: 124,545,280 D511G probably damaging Het
Col4a4 G T 1: 82,466,545 P1334T unknown Het
Creb3l4 T C 3: 90,237,738 E369G probably damaging Het
Crnkl1 T C 2: 145,919,948 K563R probably benign Het
Dbi T C 1: 120,113,477 K131E probably benign Het
Edn1 A G 13: 42,303,671 D60G probably damaging Het
Erbin T C 13: 103,834,012 N1032S probably damaging Het
Ero1l T C 14: 45,303,586 D107G probably benign Het
Glmn A T 5: 107,578,512 probably null Het
Grxcr1 T C 5: 68,110,562 probably benign Het
Itih3 T A 14: 30,909,781 K593I probably damaging Het
Kmt2b T C 7: 30,580,507 Y1356C probably damaging Het
Lrp1b C T 2: 40,750,947 C3495Y probably damaging Het
Map3k13 A T 16: 21,928,016 T950S probably damaging Het
Me1 A T 9: 86,598,748 V348D probably damaging Het
Morc2a T C 11: 3,684,042 V718A probably benign Het
Myh7 T C 14: 54,971,632 E1883G possibly damaging Het
Olfr1338 T A 4: 118,753,762 I259F possibly damaging Het
Olfr913 T G 9: 38,594,905 I228R probably damaging Het
Pdcd6ip A G 9: 113,680,181 probably benign Het
Plcb3 T A 19: 6,955,322 E1025V probably benign Het
Prkd1 T C 12: 50,383,515 probably benign Het
Rwdd4a C T 8: 47,544,112 T122M possibly damaging Het
Sdhb T G 4: 140,977,480 C251G probably damaging Het
Siglec1 A T 2: 131,079,217 I678N probably damaging Het
Snrnp70 T C 7: 45,377,377 D215G probably damaging Het
Ston1 A G 17: 88,644,443 E674G probably benign Het
Tbl3 A T 17: 24,705,252 I177N probably damaging Het
Tbl3 T C 17: 24,701,905 probably benign Het
Tnrc6c T C 11: 117,721,985 V483A probably damaging Het
Other mutations in Ppp1r26
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00975:Ppp1r26 APN 2 28453718 missense probably damaging 1.00
IGL02061:Ppp1r26 APN 2 28450627 missense possibly damaging 0.68
IGL02399:Ppp1r26 APN 2 28453280 missense probably benign
R0518:Ppp1r26 UTSW 2 28452302 missense probably damaging 1.00
R0763:Ppp1r26 UTSW 2 28450367 missense probably damaging 1.00
R1082:Ppp1r26 UTSW 2 28452134 missense probably damaging 1.00
R1477:Ppp1r26 UTSW 2 28452788 missense probably benign 0.00
R1512:Ppp1r26 UTSW 2 28451516 missense probably benign 0.01
R2157:Ppp1r26 UTSW 2 28452358 missense probably benign 0.00
R2228:Ppp1r26 UTSW 2 28453786 missense possibly damaging 0.91
R2275:Ppp1r26 UTSW 2 28452701 missense possibly damaging 0.86
R3015:Ppp1r26 UTSW 2 28452302 missense probably damaging 1.00
R4402:Ppp1r26 UTSW 2 28451606 missense probably benign 0.00
R4614:Ppp1r26 UTSW 2 28450848 missense probably benign 0.04
R5521:Ppp1r26 UTSW 2 28451426 missense probably benign 0.27
R5873:Ppp1r26 UTSW 2 28451605 missense probably benign 0.10
R5988:Ppp1r26 UTSW 2 28452554 missense probably benign 0.01
R6060:Ppp1r26 UTSW 2 28451030 missense probably benign 0.00
R7007:Ppp1r26 UTSW 2 28451159 missense probably damaging 0.99
R7501:Ppp1r26 UTSW 2 28450737 missense probably damaging 1.00
Z1176:Ppp1r26 UTSW 2 28452847 missense probably damaging 1.00
Z1177:Ppp1r26 UTSW 2 28450892 missense probably benign 0.17
Z1177:Ppp1r26 UTSW 2 28452868 missense probably benign 0.45
Z1177:Ppp1r26 UTSW 2 28453480 missense probably damaging 0.98
Posted On2013-06-21