Incidental Mutation 'R6248:Arap3'
| ID |
505651 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arap3
|
| Ensembl Gene |
ENSMUSG00000024451 |
| Gene Name |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| Synonyms |
Centd3, E030006K04Rik, DRAG1 |
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.814)
|
| Stock # |
R6248 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
38105681-38132022 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 38124407 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Glycine
at position 311
(S311G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000035662
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042944]
|
| AlphaFold |
Q8R5G7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000042944
AA Change: S311G
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000035662
Gene: ENSMUSG00000024451
AA Change: S311G
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
1 |
68 |
1.5e-7 |
SMART |
|
low complexity region
|
81 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
134 |
142 |
N/A |
INTRINSIC |
|
PH
|
283 |
376 |
3.4e-16 |
SMART |
|
PH
|
390 |
480 |
1.61e-8 |
SMART |
|
ArfGap
|
484 |
606 |
1.44e-25 |
SMART |
|
low complexity region
|
642 |
661 |
N/A |
INTRINSIC |
|
PH
|
671 |
785 |
2.86e1 |
SMART |
|
PH
|
795 |
901 |
6.87e-3 |
SMART |
|
RhoGAP
|
913 |
1089 |
2.11e-47 |
SMART |
|
Pfam:RA
|
1113 |
1206 |
6.2e-16 |
PFAM |
|
PH
|
1220 |
1323 |
3.46e-8 |
SMART |
|
low complexity region
|
1388 |
1407 |
N/A |
INTRINSIC |
|
low complexity region
|
1457 |
1469 |
N/A |
INTRINSIC |
|
low complexity region
|
1475 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1494 |
1529 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185063
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.0%
- 20x: 94.2%
|
| Validation Efficiency |
100% (92/92) |
| MGI Phenotype |
FUNCTION: This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
PHENOTYPE: Mice homozygous for a knock-out allele die around E11 exhibiting pallor, embryonic growth arrest, yolk sac and placental abnormalities, and an endothelial cell-autonomous defect in sprouting angiogenesis. Knock-in mice homozygous for a point mutation display similar angiogenesis defects. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(5) : Targeted(5)
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930523C07Rik |
T |
C |
1: 159,902,978 (GRCm39) |
S83P |
possibly damaging |
Het |
| Actr10 |
A |
T |
12: 70,999,733 (GRCm39) |
E176D |
probably benign |
Het |
| Adcy3 |
G |
A |
12: 4,258,662 (GRCm39) |
|
probably null |
Het |
| AI429214 |
T |
A |
8: 37,461,278 (GRCm39) |
I142N |
probably damaging |
Het |
| Alox12 |
A |
G |
11: 70,143,936 (GRCm39) |
L148S |
probably damaging |
Het |
| Ank3 |
A |
G |
10: 69,809,680 (GRCm39) |
I1147V |
probably benign |
Het |
| Apoc2 |
C |
T |
7: 19,407,493 (GRCm39) |
V12I |
probably benign |
Het |
| Arih2 |
G |
T |
9: 108,488,841 (GRCm39) |
H292Q |
probably damaging |
Het |
| Cdc14a |
A |
T |
3: 116,101,843 (GRCm39) |
D312E |
probably benign |
Het |
| Cdh12 |
T |
G |
15: 21,237,800 (GRCm39) |
W12G |
possibly damaging |
Het |
| Cisd2 |
A |
T |
3: 135,114,616 (GRCm39) |
N118K |
probably damaging |
Het |
| Cntnap5b |
A |
G |
1: 99,999,827 (GRCm39) |
Q195R |
probably benign |
Het |
| Cyp2r1 |
A |
G |
7: 114,161,966 (GRCm39) |
|
probably null |
Het |
| Cyp4f37 |
A |
G |
17: 32,848,864 (GRCm39) |
D244G |
possibly damaging |
Het |
| Dab1 |
C |
T |
4: 104,588,948 (GRCm39) |
A524V |
probably benign |
Het |
| Dido1 |
T |
A |
2: 180,302,048 (GRCm39) |
H1952L |
probably damaging |
Het |
| Dnah10 |
T |
A |
5: 124,871,283 (GRCm39) |
|
probably null |
Het |
| Dnal4 |
T |
A |
15: 79,646,714 (GRCm39) |
M56L |
probably damaging |
Het |
| Emilin2 |
A |
G |
17: 71,581,112 (GRCm39) |
V538A |
probably benign |
Het |
| Eps8l2 |
A |
G |
7: 140,922,015 (GRCm39) |
D31G |
probably damaging |
Het |
| Erp44 |
A |
T |
4: 48,219,479 (GRCm39) |
L112* |
probably null |
Het |
| Etl4 |
C |
T |
2: 20,813,900 (GRCm39) |
T1907I |
possibly damaging |
Het |
| Exoc3 |
A |
G |
13: 74,330,400 (GRCm39) |
F510L |
probably benign |
Het |
| Fam114a2 |
G |
T |
11: 57,383,942 (GRCm39) |
T324K |
possibly damaging |
Het |
| Fer1l4 |
G |
A |
2: 155,888,091 (GRCm39) |
R465C |
probably damaging |
Het |
| Frmd4b |
A |
C |
6: 97,436,173 (GRCm39) |
S2R |
probably benign |
Het |
| Fscn1 |
A |
T |
5: 142,946,778 (GRCm39) |
D192V |
possibly damaging |
Het |
| Gm3486 |
T |
A |
14: 41,206,472 (GRCm39) |
*200C |
probably null |
Het |
| Gusb |
A |
T |
5: 130,029,366 (GRCm39) |
H138Q |
probably benign |
Het |
| Hdac9 |
A |
T |
12: 34,578,293 (GRCm39) |
M4K |
possibly damaging |
Het |
| Hhipl1 |
G |
T |
12: 108,284,964 (GRCm39) |
R439L |
probably benign |
Het |
| Hoxd9 |
A |
G |
2: 74,528,980 (GRCm39) |
E194G |
probably benign |
Het |
| Itgb1 |
A |
G |
8: 129,448,902 (GRCm39) |
S503G |
possibly damaging |
Het |
| Kcnt2 |
T |
A |
1: 140,437,216 (GRCm39) |
C500S |
probably damaging |
Het |
| Kdm7a |
G |
A |
6: 39,123,983 (GRCm39) |
S727L |
possibly damaging |
Het |
| Klhdc4 |
A |
G |
8: 122,540,507 (GRCm39) |
F92L |
probably damaging |
Het |
| Klrb1a |
A |
G |
6: 128,596,137 (GRCm39) |
V62A |
probably damaging |
Het |
| Krit1 |
A |
G |
5: 3,863,032 (GRCm39) |
|
probably null |
Het |
| Krt40 |
A |
G |
11: 99,432,566 (GRCm39) |
I150T |
possibly damaging |
Het |
| Larp4b |
A |
G |
13: 9,208,738 (GRCm39) |
T464A |
probably benign |
Het |
| Lrrc52 |
T |
G |
1: 167,293,964 (GRCm39) |
D107A |
probably damaging |
Het |
| Mapkap1 |
G |
T |
2: 34,408,692 (GRCm39) |
V35F |
probably damaging |
Het |
| Mccc1 |
A |
G |
3: 36,044,313 (GRCm39) |
V171A |
probably damaging |
Het |
| Metap1d |
A |
T |
2: 71,346,104 (GRCm39) |
R222* |
probably null |
Het |
| Mrgpre |
G |
A |
7: 143,334,603 (GRCm39) |
A300V |
probably benign |
Het |
| Mterf1b |
C |
A |
5: 4,246,606 (GRCm39) |
N82K |
probably benign |
Het |
| Myh9 |
C |
T |
15: 77,669,422 (GRCm39) |
W533* |
probably null |
Het |
| Myom2 |
A |
G |
8: 15,148,472 (GRCm39) |
|
probably null |
Het |
| Ncor1 |
G |
A |
11: 62,257,808 (GRCm39) |
P329S |
probably damaging |
Het |
| Nr2f1 |
T |
C |
13: 78,344,611 (GRCm39) |
|
probably benign |
Het |
| Or10x1 |
T |
G |
1: 174,197,236 (GRCm39) |
V251G |
probably benign |
Het |
| Or11a4 |
T |
A |
17: 37,536,451 (GRCm39) |
L145* |
probably null |
Het |
| Or2a57 |
C |
T |
6: 43,212,838 (GRCm39) |
Q99* |
probably null |
Het |
| Or2w6 |
A |
T |
13: 21,843,244 (GRCm39) |
I83N |
possibly damaging |
Het |
| Or52p2 |
T |
C |
7: 102,237,237 (GRCm39) |
T238A |
probably benign |
Het |
| Or6c210 |
A |
G |
10: 129,496,532 (GRCm39) |
I286V |
probably benign |
Het |
| Or6z1 |
A |
T |
7: 6,504,675 (GRCm39) |
C183* |
probably null |
Het |
| Pcdha11 |
T |
C |
18: 37,138,950 (GRCm39) |
L193P |
probably benign |
Het |
| Pcdhb20 |
T |
A |
18: 37,639,285 (GRCm39) |
F604I |
probably damaging |
Het |
| Pde1a |
T |
C |
2: 79,708,545 (GRCm39) |
H291R |
probably damaging |
Het |
| Pfkm |
G |
A |
15: 98,024,260 (GRCm39) |
V423M |
probably damaging |
Het |
| Pira1 |
C |
A |
7: 3,739,337 (GRCm39) |
E510D |
probably benign |
Het |
| Pkd2l1 |
G |
T |
19: 44,146,108 (GRCm39) |
Q149K |
probably benign |
Het |
| Pkhd1l1 |
T |
A |
15: 44,392,955 (GRCm39) |
N1763K |
probably benign |
Het |
| Pla2g4a |
G |
A |
1: 149,748,338 (GRCm39) |
T282I |
probably damaging |
Het |
| Prpf39 |
A |
C |
12: 65,089,528 (GRCm39) |
N89H |
probably damaging |
Het |
| Rad54l2 |
A |
G |
9: 106,587,537 (GRCm39) |
F743L |
probably damaging |
Het |
| Raver2 |
A |
G |
4: 100,991,320 (GRCm39) |
|
probably null |
Het |
| Ric8b |
T |
C |
10: 84,783,709 (GRCm39) |
L189P |
probably damaging |
Het |
| Sccpdh |
T |
C |
1: 179,495,957 (GRCm39) |
F13L |
probably benign |
Het |
| Scd2 |
T |
C |
19: 44,291,448 (GRCm39) |
F296L |
probably damaging |
Het |
| Scg2 |
G |
T |
1: 79,414,023 (GRCm39) |
D233E |
probably benign |
Het |
| Sema5b |
C |
A |
16: 35,448,377 (GRCm39) |
|
probably null |
Het |
| Skint5 |
A |
T |
4: 113,636,286 (GRCm39) |
V644E |
unknown |
Het |
| Slc44a5 |
G |
T |
3: 153,969,678 (GRCm39) |
V612F |
possibly damaging |
Het |
| Snd1 |
C |
T |
6: 28,520,234 (GRCm39) |
R107* |
probably null |
Het |
| Sun5 |
G |
T |
2: 153,702,589 (GRCm39) |
T189K |
probably damaging |
Het |
| Tap1 |
A |
T |
17: 34,412,151 (GRCm39) |
E452V |
probably damaging |
Het |
| Tcam1 |
A |
G |
11: 106,173,652 (GRCm39) |
N32S |
probably benign |
Het |
| Tep1 |
T |
C |
14: 51,067,715 (GRCm39) |
E2167G |
probably damaging |
Het |
| Tm9sf1 |
C |
T |
14: 55,873,827 (GRCm39) |
R557H |
probably damaging |
Het |
| Tmem175 |
T |
C |
5: 108,793,821 (GRCm39) |
V317A |
probably damaging |
Het |
| Tsga13 |
A |
G |
6: 30,874,139 (GRCm39) |
V231A |
probably benign |
Het |
| Tspan12 |
A |
G |
6: 21,799,970 (GRCm39) |
S126P |
probably damaging |
Het |
| Uvrag |
G |
T |
7: 98,637,398 (GRCm39) |
D143E |
probably damaging |
Het |
| Vmn1r230 |
T |
A |
17: 21,067,036 (GRCm39) |
M75K |
possibly damaging |
Het |
| Vmn2r120 |
A |
T |
17: 57,852,287 (GRCm39) |
F10I |
probably benign |
Het |
| Vmn2r57 |
T |
C |
7: 41,049,284 (GRCm39) |
T822A |
probably benign |
Het |
| Vmn2r67 |
T |
C |
7: 84,799,768 (GRCm39) |
Y490C |
probably damaging |
Het |
| Zc3h7b |
T |
A |
15: 81,667,386 (GRCm39) |
W644R |
probably damaging |
Het |
| Zeb1 |
A |
G |
18: 5,766,962 (GRCm39) |
D491G |
probably damaging |
Het |
| Zfp709 |
TCGACG |
TCG |
8: 72,644,552 (GRCm39) |
|
probably benign |
Het |
| Zfp831 |
A |
T |
2: 174,486,308 (GRCm39) |
T328S |
possibly damaging |
Het |
|
| Other mutations in Arap3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00515:Arap3
|
APN |
18 |
38,108,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01145:Arap3
|
APN |
18 |
38,122,232 (GRCm39) |
missense |
probably benign |
|
|
IGL01154:Arap3
|
APN |
18 |
38,129,787 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL01305:Arap3
|
APN |
18 |
38,124,380 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01542:Arap3
|
APN |
18 |
38,123,889 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01543:Arap3
|
APN |
18 |
38,123,889 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01544:Arap3
|
APN |
18 |
38,123,889 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01545:Arap3
|
APN |
18 |
38,123,889 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01677:Arap3
|
APN |
18 |
38,129,700 (GRCm39) |
missense |
probably benign |
|
|
IGL01925:Arap3
|
APN |
18 |
38,117,299 (GRCm39) |
missense |
probably benign |
0.21 |
|
IGL01933:Arap3
|
APN |
18 |
38,111,506 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL02048:Arap3
|
APN |
18 |
38,130,032 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL02064:Arap3
|
APN |
18 |
38,124,754 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02207:Arap3
|
APN |
18 |
38,120,906 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02376:Arap3
|
APN |
18 |
38,111,506 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02531:Arap3
|
APN |
18 |
38,122,804 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02568:Arap3
|
APN |
18 |
38,129,711 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02640:Arap3
|
APN |
18 |
38,120,855 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02658:Arap3
|
APN |
18 |
38,124,047 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL03090:Arap3
|
APN |
18 |
38,122,165 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03352:Arap3
|
APN |
18 |
38,114,355 (GRCm39) |
splice site |
probably benign |
|
|
ANU22:Arap3
|
UTSW |
18 |
38,124,380 (GRCm39) |
critical splice donor site |
probably null |
|
|
P0016:Arap3
|
UTSW |
18 |
38,117,401 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4260001:Arap3
|
UTSW |
18 |
38,129,948 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0066:Arap3
|
UTSW |
18 |
38,129,760 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0324:Arap3
|
UTSW |
18 |
38,106,278 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0562:Arap3
|
UTSW |
18 |
38,108,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1289:Arap3
|
UTSW |
18 |
38,115,026 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1346:Arap3
|
UTSW |
18 |
38,108,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1419:Arap3
|
UTSW |
18 |
38,111,485 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1470:Arap3
|
UTSW |
18 |
38,122,249 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1470:Arap3
|
UTSW |
18 |
38,122,249 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1537:Arap3
|
UTSW |
18 |
38,122,737 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1644:Arap3
|
UTSW |
18 |
38,117,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1731:Arap3
|
UTSW |
18 |
38,122,965 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1758:Arap3
|
UTSW |
18 |
38,122,965 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1843:Arap3
|
UTSW |
18 |
38,108,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1907:Arap3
|
UTSW |
18 |
38,129,724 (GRCm39) |
missense |
probably benign |
0.28 |
|
R1954:Arap3
|
UTSW |
18 |
38,115,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2124:Arap3
|
UTSW |
18 |
38,106,403 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2135:Arap3
|
UTSW |
18 |
38,107,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2172:Arap3
|
UTSW |
18 |
38,123,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2418:Arap3
|
UTSW |
18 |
38,122,997 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2419:Arap3
|
UTSW |
18 |
38,122,997 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2907:Arap3
|
UTSW |
18 |
38,123,580 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4425:Arap3
|
UTSW |
18 |
38,111,653 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4669:Arap3
|
UTSW |
18 |
38,129,307 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4734:Arap3
|
UTSW |
18 |
38,129,328 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4815:Arap3
|
UTSW |
18 |
38,106,296 (GRCm39) |
missense |
probably benign |
|
|
R5328:Arap3
|
UTSW |
18 |
38,124,740 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5350:Arap3
|
UTSW |
18 |
38,115,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5466:Arap3
|
UTSW |
18 |
38,129,789 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5482:Arap3
|
UTSW |
18 |
38,107,727 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5572:Arap3
|
UTSW |
18 |
38,124,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5779:Arap3
|
UTSW |
18 |
38,117,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6053:Arap3
|
UTSW |
18 |
38,123,824 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6144:Arap3
|
UTSW |
18 |
38,118,486 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6166:Arap3
|
UTSW |
18 |
38,107,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6266:Arap3
|
UTSW |
18 |
38,123,844 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6385:Arap3
|
UTSW |
18 |
38,130,084 (GRCm39) |
nonsense |
probably null |
|
|
R6694:Arap3
|
UTSW |
18 |
38,124,590 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6856:Arap3
|
UTSW |
18 |
38,112,916 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7073:Arap3
|
UTSW |
18 |
38,107,495 (GRCm39) |
nonsense |
probably null |
|
|
R7297:Arap3
|
UTSW |
18 |
38,106,616 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7352:Arap3
|
UTSW |
18 |
38,106,331 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7652:Arap3
|
UTSW |
18 |
38,111,505 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7726:Arap3
|
UTSW |
18 |
38,122,520 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7747:Arap3
|
UTSW |
18 |
38,121,941 (GRCm39) |
splice site |
probably null |
|
|
R7944:Arap3
|
UTSW |
18 |
38,122,232 (GRCm39) |
missense |
probably benign |
|
|
R8152:Arap3
|
UTSW |
18 |
38,124,410 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R8338:Arap3
|
UTSW |
18 |
38,106,683 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8549:Arap3
|
UTSW |
18 |
38,106,365 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8793:Arap3
|
UTSW |
18 |
38,107,492 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8876:Arap3
|
UTSW |
18 |
38,130,077 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9142:Arap3
|
UTSW |
18 |
38,112,934 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9237:Arap3
|
UTSW |
18 |
38,112,934 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9583:Arap3
|
UTSW |
18 |
38,109,096 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9696:Arap3
|
UTSW |
18 |
38,112,905 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0011:Arap3
|
UTSW |
18 |
38,107,154 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0026:Arap3
|
UTSW |
18 |
38,118,364 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0027:Arap3
|
UTSW |
18 |
38,106,538 (GRCm39) |
splice site |
probably null |
|
|
X0066:Arap3
|
UTSW |
18 |
38,124,699 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ATGAGATCAGCATTCAATCCCC -3'
(R):5'- TGGACAAGCTCTCACCTCAG -3'
Sequencing Primer
(F):5'- ATCCCCATGGTTACAGCTGATGAG -3'
(R):5'- CTCAGGGGTAGGGCTGCTG -3'
|
| Posted On |
2018-02-28 |
Incidental Mutation