Incidental Mutation 'R6247:Chd6'
| ID |
505665 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Chd6
|
| Ensembl Gene |
ENSMUSG00000057133 |
| Gene Name |
chromodomain helicase DNA binding protein 6 |
| Synonyms |
6330406J24Rik, 5430439G14Rik |
| MMRRC Submission |
044366-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.755)
|
| Stock # |
R6247 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
160946978-161109075 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 160950048 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Threonine
at position 2463
(M2463T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042291
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039782]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039782
AA Change: M2463T
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000042291
Gene: ENSMUSG00000057133
AA Change: M2463T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
86 |
106 |
N/A |
INTRINSIC |
|
low complexity region
|
113 |
143 |
N/A |
INTRINSIC |
|
low complexity region
|
214 |
229 |
N/A |
INTRINSIC |
|
CHROMO
|
289 |
355 |
1.35e-4 |
SMART |
|
CHROMO
|
372 |
430 |
3.48e-7 |
SMART |
|
DEXDc
|
456 |
658 |
1.73e-39 |
SMART |
|
HELICc
|
812 |
896 |
3.84e-23 |
SMART |
|
low complexity region
|
1080 |
1094 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1108 |
1153 |
4e-23 |
BLAST |
|
SANT
|
1445 |
1504 |
1.51e0 |
SMART |
|
low complexity region
|
1866 |
1875 |
N/A |
INTRINSIC |
|
low complexity region
|
2048 |
2057 |
N/A |
INTRINSIC |
|
low complexity region
|
2130 |
2140 |
N/A |
INTRINSIC |
|
low complexity region
|
2277 |
2290 |
N/A |
INTRINSIC |
|
low complexity region
|
2333 |
2349 |
N/A |
INTRINSIC |
|
low complexity region
|
2437 |
2446 |
N/A |
INTRINSIC |
|
low complexity region
|
2539 |
2563 |
N/A |
INTRINSIC |
|
low complexity region
|
2652 |
2659 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.4%
- 20x: 95.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of the chromodomain/helicase/DNA-binding domain family of chromatin remodeling enzymes. This protein has been found to be specifically involved in transcription initiation and elongation. Homozygous knockout mice exhibit impaired motor coordination. A pseudogene has been identified on chromosome 8. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]
PHENOTYPE: Homozygous null mice display impaired coordination that is not due to muscle weakness or bradykinesia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933427D14Rik |
T |
C |
11: 72,158,942 (GRCm38) |
D871G |
probably benign |
Het |
| A4galt |
G |
T |
15: 83,227,819 (GRCm38) |
H254Q |
probably damaging |
Het |
| AA986860 |
C |
A |
1: 130,743,043 (GRCm38) |
T334K |
possibly damaging |
Het |
| Abca13 |
T |
C |
11: 9,403,874 (GRCm38) |
I3732T |
probably benign |
Het |
| Abcf1 |
C |
T |
17: 35,961,064 (GRCm38) |
D353N |
probably damaging |
Het |
| Adssl1 |
A |
G |
12: 112,628,356 (GRCm38) |
H83R |
probably damaging |
Het |
| Amer2 |
C |
A |
14: 60,378,872 (GRCm38) |
A172E |
probably damaging |
Het |
| Ankhd1 |
A |
G |
18: 36,654,146 (GRCm38) |
T2300A |
probably benign |
Het |
| Ano5 |
G |
A |
7: 51,566,131 (GRCm38) |
|
probably null |
Het |
| Apob |
G |
A |
12: 8,001,801 (GRCm38) |
G1109D |
probably damaging |
Het |
| Arhgef26 |
A |
T |
3: 62,380,960 (GRCm38) |
N484Y |
probably damaging |
Het |
| C6 |
A |
G |
15: 4,763,541 (GRCm38) |
D376G |
probably damaging |
Het |
| Caml |
T |
C |
13: 55,625,173 (GRCm38) |
|
probably null |
Het |
| Capn12 |
T |
C |
7: 28,888,652 (GRCm38) |
L473S |
probably benign |
Het |
| Cdk6 |
G |
A |
5: 3,344,553 (GRCm38) |
|
probably null |
Het |
| Cers5 |
A |
T |
15: 99,745,924 (GRCm38) |
C153S |
probably benign |
Het |
| Cfap206 |
T |
C |
4: 34,692,530 (GRCm38) |
M499V |
probably benign |
Het |
| Chn1 |
T |
C |
2: 73,707,006 (GRCm38) |
E58G |
possibly damaging |
Het |
| Clec4a1 |
T |
C |
6: 122,928,042 (GRCm38) |
V100A |
probably benign |
Het |
| Col7a1 |
G |
C |
9: 108,981,062 (GRCm38) |
|
probably benign |
Het |
| Csmd1 |
A |
G |
8: 16,196,235 (GRCm38) |
V1050A |
possibly damaging |
Het |
| Dab1 |
C |
T |
4: 104,731,751 (GRCm38) |
A524V |
probably benign |
Het |
| Dennd5a |
A |
T |
7: 109,898,682 (GRCm38) |
C1044S |
probably damaging |
Het |
| Dnah7b |
A |
G |
1: 46,225,888 (GRCm38) |
T2181A |
probably benign |
Het |
| Dnaic1 |
T |
C |
4: 41,605,775 (GRCm38) |
V255A |
probably benign |
Het |
| Dync2h1 |
A |
G |
9: 7,135,078 (GRCm38) |
C1518R |
probably damaging |
Het |
| Dysf |
T |
C |
6: 84,066,999 (GRCm38) |
V273A |
probably damaging |
Het |
| Eif1 |
C |
T |
11: 100,320,397 (GRCm38) |
|
probably benign |
Het |
| Eml3 |
T |
C |
19: 8,930,949 (GRCm38) |
I58T |
probably benign |
Het |
| Fam171b |
T |
A |
2: 83,879,208 (GRCm38) |
I408N |
probably damaging |
Het |
| Fchsd2 |
A |
G |
7: 101,253,540 (GRCm38) |
E351G |
probably benign |
Het |
| Focad |
G |
A |
4: 88,407,140 (GRCm38) |
A81T |
possibly damaging |
Het |
| Fpr-rs4 |
G |
A |
17: 18,022,486 (GRCm38) |
V252I |
probably benign |
Het |
| Fryl |
A |
G |
5: 73,065,481 (GRCm38) |
L1919P |
probably damaging |
Het |
| Gm12185 |
C |
T |
11: 48,915,908 (GRCm38) |
R152H |
probably damaging |
Het |
| Gm14410 |
C |
T |
2: 177,193,724 (GRCm38) |
G249E |
probably damaging |
Het |
| Gm3854 |
T |
C |
7: 6,353,946 (GRCm38) |
C253R |
probably damaging |
Het |
| Gm6685 |
A |
T |
11: 28,339,706 (GRCm38) |
S37T |
possibly damaging |
Het |
| Greb1 |
G |
A |
12: 16,716,675 (GRCm38) |
P374L |
probably damaging |
Het |
| Hdac4 |
A |
T |
1: 92,012,838 (GRCm38) |
|
probably null |
Het |
| Hecw1 |
A |
T |
13: 14,234,425 (GRCm38) |
L1099* |
probably null |
Het |
| Hivep1 |
T |
C |
13: 42,157,490 (GRCm38) |
S1069P |
probably benign |
Het |
| Itgad |
T |
C |
7: 128,185,787 (GRCm38) |
I288T |
possibly damaging |
Het |
| Kif9 |
A |
G |
9: 110,488,544 (GRCm38) |
M96V |
possibly damaging |
Het |
| Kncn |
T |
A |
4: 115,884,790 (GRCm38) |
V18E |
probably damaging |
Het |
| Lrrc74a |
G |
A |
12: 86,758,556 (GRCm38) |
G384D |
probably damaging |
Het |
| Ltb4r2 |
T |
C |
14: 55,762,651 (GRCm38) |
V243A |
probably damaging |
Het |
| Mtnr1b |
T |
A |
9: 15,862,786 (GRCm38) |
I326L |
probably benign |
Het |
| Mylip |
C |
T |
13: 45,408,481 (GRCm38) |
T253I |
probably damaging |
Het |
| Necap1 |
T |
A |
6: 122,880,652 (GRCm38) |
|
probably null |
Het |
| Nedd4 |
C |
T |
9: 72,726,438 (GRCm38) |
P409S |
probably damaging |
Het |
| Npat |
A |
T |
9: 53,545,238 (GRCm38) |
E36D |
probably damaging |
Het |
| Ovch2 |
C |
T |
7: 107,785,441 (GRCm38) |
V490M |
probably damaging |
Het |
| Pax9 |
T |
C |
12: 56,709,695 (GRCm38) |
S273P |
probably benign |
Het |
| Plce1 |
A |
G |
19: 38,745,845 (GRCm38) |
E1563G |
probably damaging |
Het |
| Podxl2 |
C |
A |
6: 88,849,317 (GRCm38) |
G336* |
probably null |
Het |
| Prdm1 |
A |
G |
10: 44,446,786 (GRCm38) |
|
probably null |
Het |
| Psme4 |
T |
C |
11: 30,853,245 (GRCm38) |
I29T |
possibly damaging |
Het |
| Ptprd |
A |
T |
4: 76,066,291 (GRCm38) |
D780E |
probably benign |
Het |
| Retsat |
T |
C |
6: 72,604,935 (GRCm38) |
M294T |
probably benign |
Het |
| Robo2 |
A |
T |
16: 73,967,784 (GRCm38) |
V652D |
probably damaging |
Het |
| Rptn |
C |
G |
3: 93,398,130 (GRCm38) |
H923Q |
possibly damaging |
Het |
| Serpinb3d |
G |
T |
1: 107,082,760 (GRCm38) |
T66K |
probably benign |
Het |
| Setd1b |
A |
T |
5: 123,158,398 (GRCm38) |
|
probably benign |
Het |
| Slc7a10 |
G |
T |
7: 35,186,587 (GRCm38) |
A36S |
possibly damaging |
Het |
| Sstr3 |
T |
A |
15: 78,539,588 (GRCm38) |
I320F |
probably damaging |
Het |
| Syne1 |
G |
T |
10: 5,349,071 (GRCm38) |
A1005E |
probably damaging |
Het |
| Syngap1 |
C |
A |
17: 26,962,957 (GRCm38) |
S975* |
probably null |
Het |
| Tinagl1 |
C |
T |
4: 130,172,932 (GRCm38) |
C124Y |
probably null |
Het |
| Tm9sf1 |
C |
T |
14: 55,636,370 (GRCm38) |
R557H |
probably damaging |
Het |
| Tmed2 |
T |
A |
5: 124,546,992 (GRCm38) |
I68K |
possibly damaging |
Het |
| Tmem104 |
A |
G |
11: 115,243,993 (GRCm38) |
T451A |
probably benign |
Het |
| Tmem141 |
T |
C |
2: 25,621,681 (GRCm38) |
|
probably null |
Het |
| Tmem184a |
C |
A |
5: 139,813,072 (GRCm38) |
V41L |
probably benign |
Het |
| Tmem39b |
C |
T |
4: 129,686,791 (GRCm38) |
V303I |
possibly damaging |
Het |
| Tsn |
T |
C |
1: 118,305,209 (GRCm38) |
I122V |
probably benign |
Het |
| Ttc41 |
G |
T |
10: 86,776,663 (GRCm38) |
V1267L |
probably benign |
Het |
| Uggt1 |
A |
T |
1: 36,163,228 (GRCm38) |
L1096Q |
probably damaging |
Het |
| Usp50 |
A |
T |
2: 126,775,793 (GRCm38) |
I244N |
probably benign |
Het |
| Vil1 |
A |
G |
1: 74,432,339 (GRCm38) |
S760G |
probably benign |
Het |
| Wasf1 |
T |
A |
10: 40,937,745 (GRCm38) |
V541E |
unknown |
Het |
| Zc3h13 |
G |
T |
14: 75,343,736 (GRCm38) |
S1721I |
probably benign |
Het |
| Zfp180 |
G |
T |
7: 24,105,105 (GRCm38) |
K316N |
probably damaging |
Het |
| Zfp709 |
TCGACG |
TCG |
8: 71,890,708 (GRCm38) |
|
probably benign |
Het |
| Zfp759 |
A |
G |
13: 67,140,460 (GRCm38) |
T692A |
probably benign |
Het |
| Zfyve26 |
A |
G |
12: 79,282,984 (GRCm38) |
V476A |
probably benign |
Het |
|
| Other mutations in Chd6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00837:Chd6
|
APN |
2 |
161,042,079 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL00899:Chd6
|
APN |
2 |
161,029,298 (GRCm38) |
splice site |
probably benign |
|
|
IGL01104:Chd6
|
APN |
2 |
160,961,927 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01295:Chd6
|
APN |
2 |
160,988,370 (GRCm38) |
splice site |
probably benign |
|
|
IGL01717:Chd6
|
APN |
2 |
160,965,259 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
IGL01795:Chd6
|
APN |
2 |
160,961,374 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01814:Chd6
|
APN |
2 |
161,059,929 (GRCm38) |
missense |
probably benign |
0.25 |
|
IGL02016:Chd6
|
APN |
2 |
160,983,678 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02104:Chd6
|
APN |
2 |
160,977,512 (GRCm38) |
missense |
probably benign |
|
|
IGL02158:Chd6
|
APN |
2 |
161,026,292 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
IGL02313:Chd6
|
APN |
2 |
160,965,675 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02472:Chd6
|
APN |
2 |
160,984,452 (GRCm38) |
splice site |
probably benign |
|
|
IGL02522:Chd6
|
APN |
2 |
160,965,796 (GRCm38) |
missense |
probably benign |
0.30 |
|
IGL02626:Chd6
|
APN |
2 |
161,039,350 (GRCm38) |
splice site |
probably benign |
|
|
IGL02727:Chd6
|
APN |
2 |
160,969,463 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02738:Chd6
|
APN |
2 |
160,965,698 (GRCm38) |
missense |
probably benign |
0.45 |
|
IGL02743:Chd6
|
APN |
2 |
160,960,263 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02800:Chd6
|
APN |
2 |
160,984,632 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02811:Chd6
|
APN |
2 |
160,990,301 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02850:Chd6
|
APN |
2 |
161,019,616 (GRCm38) |
nonsense |
probably null |
|
|
IGL02979:Chd6
|
APN |
2 |
160,966,170 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
IGL02993:Chd6
|
APN |
2 |
161,052,384 (GRCm38) |
splice site |
probably benign |
|
|
IGL03277:Chd6
|
APN |
2 |
160,983,061 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL03346:Chd6
|
APN |
2 |
160,960,362 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03357:Chd6
|
APN |
2 |
161,018,016 (GRCm38) |
splice site |
probably benign |
|
|
IGL03134:Chd6
|
UTSW |
2 |
160,965,483 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R0106:Chd6
|
UTSW |
2 |
160,967,902 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0106:Chd6
|
UTSW |
2 |
160,967,902 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0212:Chd6
|
UTSW |
2 |
161,052,847 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0363:Chd6
|
UTSW |
2 |
161,014,324 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0399:Chd6
|
UTSW |
2 |
161,052,688 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0511:Chd6
|
UTSW |
2 |
160,992,191 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0771:Chd6
|
UTSW |
2 |
161,019,580 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1147:Chd6
|
UTSW |
2 |
160,990,271 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1147:Chd6
|
UTSW |
2 |
160,990,271 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1184:Chd6
|
UTSW |
2 |
161,030,802 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1277:Chd6
|
UTSW |
2 |
160,967,815 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1396:Chd6
|
UTSW |
2 |
160,983,103 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1647:Chd6
|
UTSW |
2 |
161,042,058 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1648:Chd6
|
UTSW |
2 |
161,042,058 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1745:Chd6
|
UTSW |
2 |
160,981,667 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1766:Chd6
|
UTSW |
2 |
160,966,639 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1871:Chd6
|
UTSW |
2 |
160,990,256 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1928:Chd6
|
UTSW |
2 |
160,968,000 (GRCm38) |
splice site |
probably benign |
|
|
R1973:Chd6
|
UTSW |
2 |
160,966,387 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2200:Chd6
|
UTSW |
2 |
160,983,753 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2340:Chd6
|
UTSW |
2 |
160,965,759 (GRCm38) |
frame shift |
probably null |
|
|
R2341:Chd6
|
UTSW |
2 |
160,965,759 (GRCm38) |
frame shift |
probably null |
|
|
R2519:Chd6
|
UTSW |
2 |
161,029,876 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R2919:Chd6
|
UTSW |
2 |
160,967,880 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R3025:Chd6
|
UTSW |
2 |
160,966,552 (GRCm38) |
small deletion |
probably benign |
|
|
R3426:Chd6
|
UTSW |
2 |
160,990,255 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3427:Chd6
|
UTSW |
2 |
160,990,255 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4042:Chd6
|
UTSW |
2 |
160,988,333 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4273:Chd6
|
UTSW |
2 |
160,961,291 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4360:Chd6
|
UTSW |
2 |
160,949,856 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
R4399:Chd6
|
UTSW |
2 |
160,965,318 (GRCm38) |
missense |
probably benign |
|
|
R4458:Chd6
|
UTSW |
2 |
161,029,876 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R4583:Chd6
|
UTSW |
2 |
161,014,194 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4625:Chd6
|
UTSW |
2 |
160,969,492 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4740:Chd6
|
UTSW |
2 |
160,970,183 (GRCm38) |
missense |
probably benign |
|
|
R4765:Chd6
|
UTSW |
2 |
160,966,244 (GRCm38) |
nonsense |
probably null |
|
|
R4779:Chd6
|
UTSW |
2 |
160,949,557 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4877:Chd6
|
UTSW |
2 |
161,029,299 (GRCm38) |
splice site |
probably benign |
|
|
R5068:Chd6
|
UTSW |
2 |
160,966,369 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R5215:Chd6
|
UTSW |
2 |
160,949,953 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5275:Chd6
|
UTSW |
2 |
160,969,363 (GRCm38) |
missense |
probably benign |
|
|
R5405:Chd6
|
UTSW |
2 |
160,965,390 (GRCm38) |
missense |
probably benign |
|
|
R5598:Chd6
|
UTSW |
2 |
161,014,112 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5693:Chd6
|
UTSW |
2 |
160,965,265 (GRCm38) |
missense |
probably benign |
|
|
R5697:Chd6
|
UTSW |
2 |
161,018,051 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5715:Chd6
|
UTSW |
2 |
160,949,878 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5759:Chd6
|
UTSW |
2 |
160,983,762 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R5761:Chd6
|
UTSW |
2 |
160,957,079 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5761:Chd6
|
UTSW |
2 |
160,957,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5954:Chd6
|
UTSW |
2 |
160,965,827 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6025:Chd6
|
UTSW |
2 |
160,965,582 (GRCm38) |
missense |
probably benign |
|
|
R6104:Chd6
|
UTSW |
2 |
161,014,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6393:Chd6
|
UTSW |
2 |
160,979,487 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6452:Chd6
|
UTSW |
2 |
160,965,498 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R6468:Chd6
|
UTSW |
2 |
161,013,067 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6784:Chd6
|
UTSW |
2 |
160,966,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6803:Chd6
|
UTSW |
2 |
160,960,359 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R6869:Chd6
|
UTSW |
2 |
160,965,730 (GRCm38) |
missense |
probably benign |
|
|
R6895:Chd6
|
UTSW |
2 |
160,988,340 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6925:Chd6
|
UTSW |
2 |
161,013,127 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7061:Chd6
|
UTSW |
2 |
161,025,965 (GRCm38) |
nonsense |
probably null |
|
|
R7064:Chd6
|
UTSW |
2 |
160,950,063 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7248:Chd6
|
UTSW |
2 |
160,961,279 (GRCm38) |
nonsense |
probably null |
|
|
R7287:Chd6
|
UTSW |
2 |
161,008,392 (GRCm38) |
missense |
probably benign |
0.07 |
|
R7431:Chd6
|
UTSW |
2 |
161,026,328 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R7486:Chd6
|
UTSW |
2 |
160,950,003 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7509:Chd6
|
UTSW |
2 |
161,013,154 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7699:Chd6
|
UTSW |
2 |
161,025,943 (GRCm38) |
missense |
probably benign |
0.13 |
|
R7748:Chd6
|
UTSW |
2 |
160,966,619 (GRCm38) |
missense |
probably benign |
0.37 |
|
R7785:Chd6
|
UTSW |
2 |
160,970,175 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R8002:Chd6
|
UTSW |
2 |
160,990,321 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8261:Chd6
|
UTSW |
2 |
160,957,082 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8317:Chd6
|
UTSW |
2 |
160,990,321 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8388:Chd6
|
UTSW |
2 |
161,019,651 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8865:Chd6
|
UTSW |
2 |
161,021,069 (GRCm38) |
missense |
probably benign |
0.10 |
|
R8867:Chd6
|
UTSW |
2 |
161,021,069 (GRCm38) |
missense |
probably benign |
0.10 |
|
R8996:Chd6
|
UTSW |
2 |
160,981,623 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9091:Chd6
|
UTSW |
2 |
161,029,873 (GRCm38) |
nonsense |
probably null |
|
|
R9270:Chd6
|
UTSW |
2 |
161,029,873 (GRCm38) |
nonsense |
probably null |
|
|
R9310:Chd6
|
UTSW |
2 |
161,039,261 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9367:Chd6
|
UTSW |
2 |
161,029,864 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R9438:Chd6
|
UTSW |
2 |
160,957,158 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9756:Chd6
|
UTSW |
2 |
160,960,339 (GRCm38) |
missense |
probably benign |
|
|
Z1088:Chd6
|
UTSW |
2 |
160,966,488 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCCAACTCCAAACATCTGGG -3'
(R):5'- GATAAGCTATGCCAGGACACAG -3'
Sequencing Primer
(F):5'- TGCCTGGCAGCATCATG -3'
(R):5'- CTATGCCAGGACACAGCTGTAG -3'
|
| Posted On |
2018-02-28 |
Incidental Mutation