Incidental Mutation 'R6247:Dab1'
| ID |
505673 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dab1
|
| Ensembl Gene |
ENSMUSG00000028519 |
| Gene Name |
disabled 1 |
| Synonyms |
C630028C02Rik |
| MMRRC Submission |
044366-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.877)
|
| Stock # |
R6247 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
103476556-104602041 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 104588948 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Valine
at position 524
(A524V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102443
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106830]
[ENSMUST00000146078]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106830
AA Change: A524V
PolyPhen 2
Score 0.289 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000102443
Gene: ENSMUSG00000028519
AA Change: A524V
| Domain | Start | End | E-Value | Type |
|---|
|
PTB
|
37 |
171 |
3.51e-36 |
SMART |
|
low complexity region
|
254 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
487 |
N/A |
INTRINSIC |
|
low complexity region
|
490 |
501 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000146078
|
| SMART Domains |
Protein: ENSMUSP00000125033
Gene: ENSMUSG00000028519
| Domain | Start | End | E-Value | Type |
|---|
|
PTB
|
37 |
171 |
3.51e-36 |
SMART |
|
low complexity region
|
235 |
242 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.2232 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.4%
- 20x: 95.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]
PHENOTYPE: Homozygous null display unstable gait and whole-body tremor with a hypoplastic cerebellum devoid of folia, a probable consequence of defective neuronal migration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933427D14Rik |
T |
C |
11: 72,049,768 (GRCm39) |
D871G |
probably benign |
Het |
| A4galt |
G |
T |
15: 83,112,020 (GRCm39) |
H254Q |
probably damaging |
Het |
| AA986860 |
C |
A |
1: 130,670,780 (GRCm39) |
T334K |
possibly damaging |
Het |
| Abca13 |
T |
C |
11: 9,353,874 (GRCm39) |
I3732T |
probably benign |
Het |
| Abcf1 |
C |
T |
17: 36,271,956 (GRCm39) |
D353N |
probably damaging |
Het |
| Adss1 |
A |
G |
12: 112,594,790 (GRCm39) |
H83R |
probably damaging |
Het |
| Amer2 |
C |
A |
14: 60,616,321 (GRCm39) |
A172E |
probably damaging |
Het |
| Ankhd1 |
A |
G |
18: 36,787,199 (GRCm39) |
T2300A |
probably benign |
Het |
| Ano5 |
G |
A |
7: 51,215,879 (GRCm39) |
|
probably null |
Het |
| Apob |
G |
A |
12: 8,051,801 (GRCm39) |
G1109D |
probably damaging |
Het |
| Arhgef26 |
A |
T |
3: 62,288,381 (GRCm39) |
N484Y |
probably damaging |
Het |
| C6 |
A |
G |
15: 4,793,023 (GRCm39) |
D376G |
probably damaging |
Het |
| Caml |
T |
C |
13: 55,772,986 (GRCm39) |
|
probably null |
Het |
| Capn12 |
T |
C |
7: 28,588,077 (GRCm39) |
L473S |
probably benign |
Het |
| Cdk6 |
G |
A |
5: 3,394,553 (GRCm39) |
|
probably null |
Het |
| Cers5 |
A |
T |
15: 99,643,805 (GRCm39) |
C153S |
probably benign |
Het |
| Cfap206 |
T |
C |
4: 34,692,530 (GRCm39) |
M499V |
probably benign |
Het |
| Chd6 |
A |
G |
2: 160,791,968 (GRCm39) |
M2463T |
probably damaging |
Het |
| Chn1 |
T |
C |
2: 73,537,350 (GRCm39) |
E58G |
possibly damaging |
Het |
| Clec4a1 |
T |
C |
6: 122,905,001 (GRCm39) |
V100A |
probably benign |
Het |
| Col7a1 |
G |
C |
9: 108,810,130 (GRCm39) |
|
probably benign |
Het |
| Csmd1 |
A |
G |
8: 16,246,249 (GRCm39) |
V1050A |
possibly damaging |
Het |
| Dennd5a |
A |
T |
7: 109,497,889 (GRCm39) |
C1044S |
probably damaging |
Het |
| Dnah7b |
A |
G |
1: 46,265,048 (GRCm39) |
T2181A |
probably benign |
Het |
| Dnai1 |
T |
C |
4: 41,605,775 (GRCm39) |
V255A |
probably benign |
Het |
| Dync2h1 |
A |
G |
9: 7,135,078 (GRCm39) |
C1518R |
probably damaging |
Het |
| Dysf |
T |
C |
6: 84,043,981 (GRCm39) |
V273A |
probably damaging |
Het |
| Eif1 |
C |
T |
11: 100,211,223 (GRCm39) |
|
probably benign |
Het |
| Eml3 |
T |
C |
19: 8,908,313 (GRCm39) |
I58T |
probably benign |
Het |
| Fam171b |
T |
A |
2: 83,709,552 (GRCm39) |
I408N |
probably damaging |
Het |
| Fchsd2 |
A |
G |
7: 100,902,747 (GRCm39) |
E351G |
probably benign |
Het |
| Focad |
G |
A |
4: 88,325,377 (GRCm39) |
A81T |
possibly damaging |
Het |
| Fpr-rs4 |
G |
A |
17: 18,242,748 (GRCm39) |
V252I |
probably benign |
Het |
| Fryl |
A |
G |
5: 73,222,824 (GRCm39) |
L1919P |
probably damaging |
Het |
| Gm12185 |
C |
T |
11: 48,806,735 (GRCm39) |
R152H |
probably damaging |
Het |
| Gm14410 |
C |
T |
2: 176,885,517 (GRCm39) |
G249E |
probably damaging |
Het |
| Gm6685 |
A |
T |
11: 28,289,706 (GRCm39) |
S37T |
possibly damaging |
Het |
| Greb1 |
G |
A |
12: 16,766,676 (GRCm39) |
P374L |
probably damaging |
Het |
| Hdac4 |
A |
T |
1: 91,940,560 (GRCm39) |
|
probably null |
Het |
| Hecw1 |
A |
T |
13: 14,409,010 (GRCm39) |
L1099* |
probably null |
Het |
| Hivep1 |
T |
C |
13: 42,310,966 (GRCm39) |
S1069P |
probably benign |
Het |
| Itgad |
T |
C |
7: 127,784,959 (GRCm39) |
I288T |
possibly damaging |
Het |
| Kif9 |
A |
G |
9: 110,317,612 (GRCm39) |
M96V |
possibly damaging |
Het |
| Kncn |
T |
A |
4: 115,741,987 (GRCm39) |
V18E |
probably damaging |
Het |
| Lrrc74a |
G |
A |
12: 86,805,330 (GRCm39) |
G384D |
probably damaging |
Het |
| Ltb4r2 |
T |
C |
14: 56,000,108 (GRCm39) |
V243A |
probably damaging |
Het |
| Mtnr1b |
T |
A |
9: 15,774,082 (GRCm39) |
I326L |
probably benign |
Het |
| Mylip |
C |
T |
13: 45,561,957 (GRCm39) |
T253I |
probably damaging |
Het |
| Necap1 |
T |
A |
6: 122,857,611 (GRCm39) |
|
probably null |
Het |
| Nedd4 |
C |
T |
9: 72,633,720 (GRCm39) |
P409S |
probably damaging |
Het |
| Npat |
A |
T |
9: 53,456,538 (GRCm39) |
E36D |
probably damaging |
Het |
| Ovch2 |
C |
T |
7: 107,384,648 (GRCm39) |
V490M |
probably damaging |
Het |
| Pax9 |
T |
C |
12: 56,756,480 (GRCm39) |
S273P |
probably benign |
Het |
| Plce1 |
A |
G |
19: 38,734,289 (GRCm39) |
E1563G |
probably damaging |
Het |
| Podxl2 |
C |
A |
6: 88,826,299 (GRCm39) |
G336* |
probably null |
Het |
| Prdm1 |
A |
G |
10: 44,322,782 (GRCm39) |
|
probably null |
Het |
| Psme4 |
T |
C |
11: 30,803,245 (GRCm39) |
I29T |
possibly damaging |
Het |
| Ptprd |
A |
T |
4: 75,984,528 (GRCm39) |
D780E |
probably benign |
Het |
| Retsat |
T |
C |
6: 72,581,918 (GRCm39) |
M294T |
probably benign |
Het |
| Robo2 |
A |
T |
16: 73,764,672 (GRCm39) |
V652D |
probably damaging |
Het |
| Rptn |
C |
G |
3: 93,305,437 (GRCm39) |
H923Q |
possibly damaging |
Het |
| Serpinb3d |
G |
T |
1: 107,010,490 (GRCm39) |
T66K |
probably benign |
Het |
| Setd1b |
A |
T |
5: 123,296,461 (GRCm39) |
|
probably benign |
Het |
| Slc7a10 |
G |
T |
7: 34,886,012 (GRCm39) |
A36S |
possibly damaging |
Het |
| Sstr3 |
T |
A |
15: 78,423,788 (GRCm39) |
I320F |
probably damaging |
Het |
| Syne1 |
G |
T |
10: 5,299,071 (GRCm39) |
A1005E |
probably damaging |
Het |
| Syngap1 |
C |
A |
17: 27,181,931 (GRCm39) |
S975* |
probably null |
Het |
| Tinagl1 |
C |
T |
4: 130,066,725 (GRCm39) |
C124Y |
probably null |
Het |
| Tm9sf1 |
C |
T |
14: 55,873,827 (GRCm39) |
R557H |
probably damaging |
Het |
| Tmed2 |
T |
A |
5: 124,685,055 (GRCm39) |
I68K |
possibly damaging |
Het |
| Tmem104 |
A |
G |
11: 115,134,819 (GRCm39) |
T451A |
probably benign |
Het |
| Tmem141 |
T |
C |
2: 25,511,693 (GRCm39) |
|
probably null |
Het |
| Tmem184a |
C |
A |
5: 139,798,827 (GRCm39) |
V41L |
probably benign |
Het |
| Tmem39b |
C |
T |
4: 129,580,584 (GRCm39) |
V303I |
possibly damaging |
Het |
| Tsn |
T |
C |
1: 118,232,939 (GRCm39) |
I122V |
probably benign |
Het |
| Ttc41 |
G |
T |
10: 86,612,527 (GRCm39) |
V1267L |
probably benign |
Het |
| Uggt1 |
A |
T |
1: 36,202,309 (GRCm39) |
L1096Q |
probably damaging |
Het |
| Usp50 |
A |
T |
2: 126,617,713 (GRCm39) |
I244N |
probably benign |
Het |
| Vil1 |
A |
G |
1: 74,471,498 (GRCm39) |
S760G |
probably benign |
Het |
| Wasf1 |
T |
A |
10: 40,813,741 (GRCm39) |
V541E |
unknown |
Het |
| Zc3h13 |
G |
T |
14: 75,581,176 (GRCm39) |
S1721I |
probably benign |
Het |
| Zfp180 |
G |
T |
7: 23,804,530 (GRCm39) |
K316N |
probably damaging |
Het |
| Zfp582 |
T |
C |
7: 6,356,945 (GRCm39) |
C253R |
probably damaging |
Het |
| Zfp709 |
TCGACG |
TCG |
8: 72,644,552 (GRCm39) |
|
probably benign |
Het |
| Zfp759 |
A |
G |
13: 67,288,524 (GRCm39) |
T692A |
probably benign |
Het |
| Zfyve26 |
A |
G |
12: 79,329,758 (GRCm39) |
V476A |
probably benign |
Het |
|
| Other mutations in Dab1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00087:Dab1
|
APN |
4 |
104,535,950 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL00087:Dab1
|
APN |
4 |
104,536,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00328:Dab1
|
APN |
4 |
104,545,635 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL00756:Dab1
|
APN |
4 |
104,585,075 (GRCm39) |
missense |
probably benign |
|
|
IGL02074:Dab1
|
APN |
4 |
104,585,051 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02286:Dab1
|
APN |
4 |
104,537,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02986:Dab1
|
APN |
4 |
104,336,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03008:Dab1
|
APN |
4 |
104,584,777 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03133:Dab1
|
APN |
4 |
104,584,777 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL03375:Dab1
|
APN |
4 |
104,538,798 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
LCD18:Dab1
|
UTSW |
4 |
103,903,769 (GRCm39) |
intron |
probably benign |
|
|
R0027:Dab1
|
UTSW |
4 |
104,561,396 (GRCm39) |
intron |
probably benign |
|
|
R0466:Dab1
|
UTSW |
4 |
104,577,747 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0838:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R0840:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1086:Dab1
|
UTSW |
4 |
104,185,769 (GRCm39) |
intron |
probably benign |
|
|
R1598:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1640:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1699:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1749:Dab1
|
UTSW |
4 |
104,185,495 (GRCm39) |
intron |
probably benign |
|
|
R1770:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1846:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1847:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1848:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1885:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1986:Dab1
|
UTSW |
4 |
104,470,412 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1990:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2006:Dab1
|
UTSW |
4 |
104,462,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2030:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2032:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2034:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2061:Dab1
|
UTSW |
4 |
104,535,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2088:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2089:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2091:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2091:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2092:Dab1
|
UTSW |
4 |
104,535,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2193:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2194:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2361:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2362:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2391:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2424:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2865:Dab1
|
UTSW |
4 |
104,537,343 (GRCm39) |
missense |
probably benign |
|
|
R3118:Dab1
|
UTSW |
4 |
104,537,266 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3716:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3718:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3740:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3742:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3965:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4057:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4393:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4396:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4418:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4607:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4608:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4648:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4693:Dab1
|
UTSW |
4 |
104,536,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4701:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4730:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4760:Dab1
|
UTSW |
4 |
104,589,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4927:Dab1
|
UTSW |
4 |
104,561,449 (GRCm39) |
missense |
probably benign |
|
|
R5173:Dab1
|
UTSW |
4 |
104,545,645 (GRCm39) |
splice site |
probably null |
|
|
R5503:Dab1
|
UTSW |
4 |
104,369,461 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6199:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6200:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6207:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6224:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6227:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6228:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6229:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6246:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6248:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6249:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6250:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6258:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6259:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6260:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6505:Dab1
|
UTSW |
4 |
104,369,461 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6817:Dab1
|
UTSW |
4 |
104,536,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7305:Dab1
|
UTSW |
4 |
104,570,987 (GRCm39) |
missense |
|
|
|
R7709:Dab1
|
UTSW |
4 |
104,577,756 (GRCm39) |
nonsense |
probably null |
|
|
R7894:Dab1
|
UTSW |
4 |
104,589,335 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8142:Dab1
|
UTSW |
4 |
104,535,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8462:Dab1
|
UTSW |
4 |
104,561,404 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8472:Dab1
|
UTSW |
4 |
104,336,439 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9138:Dab1
|
UTSW |
4 |
104,588,929 (GRCm39) |
nonsense |
probably null |
|
|
R9311:Dab1
|
UTSW |
4 |
104,369,463 (GRCm39) |
critical splice donor site |
probably null |
|
|
RF017:Dab1
|
UTSW |
4 |
104,570,849 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1088:Dab1
|
UTSW |
4 |
104,336,429 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Dab1
|
UTSW |
4 |
104,585,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Dab1
|
UTSW |
4 |
104,584,937 (GRCm39) |
missense |
probably benign |
0.05 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGGGATATAAATGGCTGTGGC -3'
(R):5'- TTTACAGGAGGCTGAAACTTCCC -3'
Sequencing Primer
(F):5'- GGATATAAATGGCTGTGGCTTATATG -3'
(R):5'- TGAAACTTCCCCCAGAGGATG -3'
|
| Posted On |
2018-02-28 |
Incidental Mutation