Mutagenetix > Incidental Mutation

Incidental Mutation 'R6250:Fcgbpl1'

505913

Institutional Source

Beutler Lab

Gene Symbol

Fcgbpl1

Ensembl Gene

ENSMUSG00000078776

Gene Name

Fc fragment of IgG binding protein like 1

Synonyms

9530053A07Rik

MMRRC Submission

044367-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.098) question?

Stock #

R6250 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

27828891-27864236 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 27850139 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glycine to Aspartic acid at position 1195 (G1195D)

Ref Sequence

ENSEMBL: ENSMUSP00000114986 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000059886] [ENSMUST00000150948]

AlphaFold

E9PVG8

Predicted Effect

probably damaging
Transcript: ENSMUST00000059886
AA Change: G1195D

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000056479
Gene: ENSMUSG00000078776
AA Change: G1195D

Domain	Start	End	E-Value	Type
low complexity region	8	24	N/A	INTRINSIC
FOLN	27	49	1.23e-4	SMART
VWD	46	211	1.5e-40	SMART
C8	251	326	4.31e-33	SMART
Pfam:TIL	329	383	2e-13	PFAM
VWC	385	448	1.02e0	SMART
VWD	439	603	4.32e-32	SMART
C8	640	715	4.54e-9	SMART
Pfam:TIL	718	771	1.6e-12	PFAM
VWC	773	826	1.1e0	SMART
FOLN	805	827	6.87e1	SMART
VWD	825	988	7.92e-40	SMART
C8	1033	1108	5.1e-35	SMART
Pfam:TIL	1111	1164	7.6e-11	PFAM
VWC	1166	1224	1.1e-2	SMART
FOLN	1197	1219	9.55e-1	SMART
FOLN	1223	1245	5.38e1	SMART
VWD	1241	1410	9.04e-35	SMART
C8	1450	1526	9.54e-26	SMART
low complexity region	1540	1550	N/A	INTRINSIC
EGF_like	1557	1580	5.34e1	SMART
VWC	1588	1681	3.21e-3	SMART
VWD	1639	1806	7.3e-30	SMART
C8	1838	1913	2.44e-32	SMART
EGF_like	1941	1964	4.46e1	SMART
VWC	1971	2062	2.85e-1	SMART
VWD	2022	2178	1.32e-27	SMART
low complexity region	2199	2212	N/A	INTRINSIC
C8	2219	2294	1.43e-29	SMART
Pfam:TIL	2297	2350	1.1e-11	PFAM
FOLN	2383	2405	5.68e1	SMART
VWD	2402	2564	4.58e-4	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000150948
AA Change: G1195D

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000114986
Gene: ENSMUSG00000078776
AA Change: G1195D

Domain	Start	End	E-Value	Type
low complexity region	8	24	N/A	INTRINSIC
FOLN	27	49	1.23e-4	SMART
VWD	46	211	1.5e-40	SMART
C8	251	326	4.31e-33	SMART
Pfam:TIL	329	383	2e-13	PFAM
VWC	385	448	1.02e0	SMART
VWD	439	603	4.32e-32	SMART
C8	640	715	4.54e-9	SMART
Pfam:TIL	718	771	1.6e-12	PFAM
VWC	773	826	1.1e0	SMART
FOLN	805	827	6.87e1	SMART
VWD	825	988	7.92e-40	SMART
C8	1033	1108	5.1e-35	SMART
Pfam:TIL	1111	1164	7.6e-11	PFAM
VWC	1166	1224	1.1e-2	SMART
FOLN	1197	1219	9.55e-1	SMART
FOLN	1223	1245	5.38e1	SMART
VWD	1241	1410	9.04e-35	SMART
C8	1450	1526	9.54e-26	SMART
low complexity region	1540	1550	N/A	INTRINSIC
EGF_like	1557	1580	5.34e1	SMART
VWC	1588	1681	3.21e-3	SMART
VWD	1639	1806	7.3e-30	SMART
C8	1838	1913	2.44e-32	SMART
EGF_like	1941	1964	4.46e1	SMART
VWC	1971	2062	2.85e-1	SMART
VWD	2022	2178	1.32e-27	SMART
low complexity region	2199	2212	N/A	INTRINSIC
C8	2219	2294	1.43e-29	SMART
Pfam:TIL	2297	2350	1.1e-11	PFAM
FOLN	2383	2405	5.68e1	SMART
VWD	2402	2564	4.58e-4	SMART

Coding Region Coverage

1x: 99.9%
3x: 99.7%
10x: 98.4%
20x: 95.5%

Validation Efficiency

98% (60/61)

Allele List at MGI

Other mutations in this stock

Total: 59 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abhd12	T	C	2: 150,681,667 (GRCm39)	Y241C	probably damaging	Het
Ak9	T	C	10: 41,265,030 (GRCm39)	V929A	possibly damaging	Het
Ap3s1	T	C	18: 46,887,514 (GRCm39)	F49S	probably damaging	Het
Atp9b	T	C	18: 80,799,736 (GRCm39)	H801R	probably benign	Het
B430218F22Rik	A	G	13: 118,523,944 (GRCm39)		probably benign	Het
Ccnd3	T	A	17: 47,908,487 (GRCm39)	L186*	probably null	Het
Cnbd1	T	A	4: 19,098,255 (GRCm39)	Q55L	probably benign	Het
Commd10	A	G	18: 47,096,755 (GRCm39)	E54G	probably damaging	Het
Cplx3	A	G	9: 57,522,907 (GRCm39)	V151A	probably benign	Het
D6Ertd527e	G	A	6: 87,088,194 (GRCm39)	G119D	unknown	Het
Dab1	C	T	4: 104,588,948 (GRCm39)	A524V	probably benign	Het
Disp2	A	T	2: 118,621,247 (GRCm39)	I660F	probably damaging	Het
Eef1a2	A	G	2: 180,792,853 (GRCm39)	F211L	possibly damaging	Het
Epb41	A	T	4: 131,717,184 (GRCm39)	F323L	probably damaging	Het
Eps8l3	A	T	3: 107,797,781 (GRCm39)	I403F	probably benign	Het
Ercc5	T	A	1: 44,203,209 (GRCm39)	V282D	probably damaging	Het
Faim	A	T	9: 98,874,176 (GRCm39)	M1L	probably benign	Het
Fbxo24	A	G	5: 137,619,543 (GRCm39)	F111L	probably damaging	Het
Glrx	A	T	13: 75,988,229 (GRCm39)	I48F	probably damaging	Het
Gucy2g	A	T	19: 55,205,856 (GRCm39)	L668Q	probably damaging	Het
Hectd4	A	G	5: 121,477,561 (GRCm39)	D2828G	possibly damaging	Het
Hivep2	T	C	10: 14,007,503 (GRCm39)	V1367A	probably benign	Het
Hrob	A	G	11: 102,145,888 (GRCm39)	T55A	probably benign	Het
Ipo13	A	G	4: 117,769,351 (GRCm39)	V147A	possibly damaging	Het
Jchain	T	C	5: 88,674,034 (GRCm39)	T37A	probably benign	Het
Kif1b	A	G	4: 149,298,100 (GRCm39)	V1034A	probably benign	Het
Krt25	T	A	11: 99,211,989 (GRCm39)	N216I	probably damaging	Het
Mfsd4b1	T	C	10: 39,879,106 (GRCm39)	S264G	possibly damaging	Het
Mxra8	G	T	4: 155,925,546 (GRCm39)	R82L	possibly damaging	Het
Nlrp1b	A	T	11: 71,072,625 (GRCm39)	I406N	probably benign	Het
Or13c7	T	C	4: 43,854,363 (GRCm39)	L18P	possibly damaging	Het
Or2y11	A	T	11: 49,442,711 (GRCm39)	I46F	probably damaging	Het
Or5h23	G	A	16: 58,906,195 (GRCm39)	S217F	probably damaging	Het
Pak5	T	C	2: 136,016,189 (GRCm39)		probably benign	Het
Pcsk4	T	C	10: 80,161,426 (GRCm39)	R222G	probably benign	Het
Pik3cb	A	C	9: 98,976,651 (GRCm39)	F149V	probably benign	Het
Plscr4	G	A	9: 92,366,881 (GRCm39)	R165Q	possibly damaging	Het
Ppp2r2a	A	T	14: 67,276,403 (GRCm39)	V34E	probably damaging	Het
Prpf8	T	G	11: 75,384,334 (GRCm39)	S659R	possibly damaging	Het
Ptprd	A	G	4: 76,047,232 (GRCm39)	S342P	probably damaging	Het
Pum2	T	C	12: 8,794,755 (GRCm39)		probably null	Het
Ranbp3	T	G	17: 56,984,208 (GRCm39)		probably null	Het
Rassf7	A	G	7: 140,797,156 (GRCm39)	E123G	probably damaging	Het
Rcor1	G	T	12: 111,078,311 (GRCm39)	A469S	probably benign	Het
Rcor3	G	T	1: 191,785,196 (GRCm39)	P524Q	probably damaging	Het
Rnf44	A	T	13: 54,829,920 (GRCm39)		probably null	Het
Rtf1	T	C	2: 119,505,658 (GRCm39)	V37A	unknown	Het
Sdc4	A	T	2: 164,273,138 (GRCm39)	D57E	probably damaging	Het
Setbp1	T	C	18: 78,901,217 (GRCm39)	T817A	probably benign	Het
Setd1a	A	G	7: 127,390,471 (GRCm39)	E506G	unknown	Het
Slc30a8	G	A	15: 52,198,545 (GRCm39)	R330Q	probably benign	Het
Snx22	C	A	9: 65,976,923 (GRCm39)	E14*	probably null	Het
Spata31d1a	A	G	13: 59,849,615 (GRCm39)	S838P	possibly damaging	Het
Sprr4	G	T	3: 92,407,770 (GRCm39)	Q11K	unknown	Het
Trpm3	A	G	19: 22,887,418 (GRCm39)	N839S	probably benign	Het
Vps9d1	T	C	8: 123,974,947 (GRCm39)		probably null	Het
Vwa3b	T	C	1: 37,090,966 (GRCm39)		probably null	Het
Ythdf1	T	C	2: 180,552,893 (GRCm39)	T414A	probably damaging	Het
Zfp709	TCGACG	TCG	8: 72,644,552 (GRCm39)		probably benign	Het

Other mutations in Fcgbpl1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00435:Fcgbpl1	APN	7	27,863,953 (GRCm39)	missense	probably damaging	1.00
IGL00757:Fcgbpl1	APN	7	27,853,870 (GRCm39)	missense	probably damaging	1.00
IGL01015:Fcgbpl1	APN	7	27,854,743 (GRCm39)	missense	probably damaging	1.00
IGL01079:Fcgbpl1	APN	7	27,839,203 (GRCm39)	missense	probably damaging	0.99
IGL01343:Fcgbpl1	APN	7	27,850,127 (GRCm39)	missense	probably benign	0.19
IGL01420:Fcgbpl1	APN	7	27,839,558 (GRCm39)	missense	probably benign	0.28
IGL01604:Fcgbpl1	APN	7	27,854,749 (GRCm39)	missense	probably benign	0.11
IGL01666:Fcgbpl1	APN	7	27,852,717 (GRCm39)	missense	probably damaging	1.00
IGL02002:Fcgbpl1	APN	7	27,852,221 (GRCm39)	missense	probably damaging	1.00
IGL02036:Fcgbpl1	APN	7	27,836,950 (GRCm39)	missense	possibly damaging	0.82
IGL02126:Fcgbpl1	APN	7	27,839,281 (GRCm39)	missense	probably damaging	1.00
IGL02150:Fcgbpl1	APN	7	27,846,204 (GRCm39)	nonsense	probably null
IGL02219:Fcgbpl1	APN	7	27,854,060 (GRCm39)	missense	probably damaging	1.00
IGL02563:Fcgbpl1	APN	7	27,857,317 (GRCm39)	missense	probably benign
IGL02804:Fcgbpl1	APN	7	27,852,795 (GRCm39)	missense	probably benign	0.00
IGL02830:Fcgbpl1	APN	7	27,862,348 (GRCm39)	missense	probably damaging	1.00
IGL02943:Fcgbpl1	APN	7	27,846,613 (GRCm39)	missense	probably damaging	1.00
IGL02977:Fcgbpl1	APN	7	27,863,797 (GRCm39)	missense	possibly damaging	0.83
IGL03231:Fcgbpl1	APN	7	27,853,147 (GRCm39)	missense	possibly damaging	0.95
IGL03304:Fcgbpl1	APN	7	27,841,667 (GRCm39)	missense	probably damaging	0.99
herz	UTSW	7	27,853,264 (GRCm39)	missense	possibly damaging	0.72
pulse	UTSW	7	27,853,174 (GRCm39)	missense	probably damaging	1.00
Sinusoidal	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
PIT4378001:Fcgbpl1	UTSW	7	27,853,889 (GRCm39)	missense	possibly damaging	0.61
R0023:Fcgbpl1	UTSW	7	27,852,837 (GRCm39)	missense	probably benign	0.00
R0131:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0131:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0132:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0158:Fcgbpl1	UTSW	7	27,854,917 (GRCm39)	missense	probably damaging	1.00
R0230:Fcgbpl1	UTSW	7	27,856,250 (GRCm39)	missense	probably damaging	1.00
R0310:Fcgbpl1	UTSW	7	27,841,699 (GRCm39)	missense	probably benign	0.04
R0448:Fcgbpl1	UTSW	7	27,839,660 (GRCm39)	missense	probably benign	0.03
R0462:Fcgbpl1	UTSW	7	27,836,765 (GRCm39)	missense	probably damaging	1.00
R0481:Fcgbpl1	UTSW	7	27,853,174 (GRCm39)	missense	probably damaging	1.00
R0497:Fcgbpl1	UTSW	7	27,846,890 (GRCm39)	missense	probably damaging	1.00
R0556:Fcgbpl1	UTSW	7	27,858,803 (GRCm39)	missense	probably benign
R0562:Fcgbpl1	UTSW	7	27,862,115 (GRCm39)	missense	probably benign	0.30
R0586:Fcgbpl1	UTSW	7	27,836,516 (GRCm39)	missense	probably damaging	0.99
R0924:Fcgbpl1	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
R0930:Fcgbpl1	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
R1103:Fcgbpl1	UTSW	7	27,853,945 (GRCm39)	missense	probably damaging	1.00
R1213:Fcgbpl1	UTSW	7	27,857,098 (GRCm39)	missense	probably damaging	1.00
R1292:Fcgbpl1	UTSW	7	27,842,219 (GRCm39)	splice site	probably benign
R1368:Fcgbpl1	UTSW	7	27,858,903 (GRCm39)	missense	possibly damaging	0.89
R1451:Fcgbpl1	UTSW	7	27,836,582 (GRCm39)	missense	probably damaging	1.00
R1477:Fcgbpl1	UTSW	7	27,856,518 (GRCm39)	missense	probably benign	0.01
R1538:Fcgbpl1	UTSW	7	27,854,917 (GRCm39)	missense	probably damaging	1.00
R1655:Fcgbpl1	UTSW	7	27,846,535 (GRCm39)	missense	probably damaging	0.98
R1697:Fcgbpl1	UTSW	7	27,853,772 (GRCm39)	missense	probably damaging	1.00
R1741:Fcgbpl1	UTSW	7	27,857,279 (GRCm39)	missense	probably damaging	0.98
R1796:Fcgbpl1	UTSW	7	27,854,797 (GRCm39)	missense	probably damaging	1.00
R1853:Fcgbpl1	UTSW	7	27,854,971 (GRCm39)	nonsense	probably null
R1861:Fcgbpl1	UTSW	7	27,854,157 (GRCm39)	missense	probably damaging	1.00
R1909:Fcgbpl1	UTSW	7	27,843,773 (GRCm39)	missense	possibly damaging	0.52
R1971:Fcgbpl1	UTSW	7	27,830,937 (GRCm39)	missense	possibly damaging	0.90
R1990:Fcgbpl1	UTSW	7	27,853,785 (GRCm39)	missense	probably damaging	0.98
R2020:Fcgbpl1	UTSW	7	27,855,019 (GRCm39)	missense	probably benign
R2084:Fcgbpl1	UTSW	7	27,856,960 (GRCm39)	missense	probably damaging	1.00
R2125:Fcgbpl1	UTSW	7	27,857,447 (GRCm39)	missense	probably benign	0.00
R2132:Fcgbpl1	UTSW	7	27,854,899 (GRCm39)	missense	probably damaging	1.00
R2513:Fcgbpl1	UTSW	7	27,831,060 (GRCm39)	missense	probably damaging	0.99
R2913:Fcgbpl1	UTSW	7	27,863,732 (GRCm39)	missense	probably damaging	1.00
R3150:Fcgbpl1	UTSW	7	27,853,620 (GRCm39)	missense	probably benign	0.21
R3499:Fcgbpl1	UTSW	7	27,853,980 (GRCm39)	missense	probably benign	0.42
R3702:Fcgbpl1	UTSW	7	27,857,203 (GRCm39)	missense	probably damaging	1.00
R3881:Fcgbpl1	UTSW	7	27,839,463 (GRCm39)	nonsense	probably null
R3938:Fcgbpl1	UTSW	7	27,853,719 (GRCm39)	missense	probably damaging	1.00
R4050:Fcgbpl1	UTSW	7	27,852,410 (GRCm39)	missense	possibly damaging	0.55
R4152:Fcgbpl1	UTSW	7	27,856,322 (GRCm39)	missense	possibly damaging	0.47
R4168:Fcgbpl1	UTSW	7	27,836,534 (GRCm39)	missense	probably benign	0.05
R4235:Fcgbpl1	UTSW	7	27,856,073 (GRCm39)	missense	probably damaging	0.99
R4241:Fcgbpl1	UTSW	7	27,853,760 (GRCm39)	missense	probably damaging	1.00
R4363:Fcgbpl1	UTSW	7	27,846,331 (GRCm39)	missense	probably damaging	1.00
R4460:Fcgbpl1	UTSW	7	27,852,281 (GRCm39)	missense	probably benign	0.17
R4463:Fcgbpl1	UTSW	7	27,850,144 (GRCm39)	missense	probably benign
R4841:Fcgbpl1	UTSW	7	27,850,147 (GRCm39)	missense	probably damaging	1.00
R4842:Fcgbpl1	UTSW	7	27,850,147 (GRCm39)	missense	probably damaging	1.00
R4876:Fcgbpl1	UTSW	7	27,842,225 (GRCm39)	intron	probably benign
R4905:Fcgbpl1	UTSW	7	27,856,408 (GRCm39)	missense	possibly damaging	0.93
R4997:Fcgbpl1	UTSW	7	27,843,349 (GRCm39)	missense	possibly damaging	0.77
R5091:Fcgbpl1	UTSW	7	27,856,383 (GRCm39)	missense	probably benign	0.44
R5159:Fcgbpl1	UTSW	7	27,852,733 (GRCm39)	missense	probably benign	0.09
R5326:Fcgbpl1	UTSW	7	27,854,914 (GRCm39)	missense	probably damaging	0.98
R5396:Fcgbpl1	UTSW	7	27,839,608 (GRCm39)	missense	probably benign
R5441:Fcgbpl1	UTSW	7	27,856,339 (GRCm39)	missense	probably damaging	1.00
R5480:Fcgbpl1	UTSW	7	27,857,424 (GRCm39)	nonsense	probably null
R5542:Fcgbpl1	UTSW	7	27,854,914 (GRCm39)	missense	probably damaging	0.98
R5571:Fcgbpl1	UTSW	7	27,855,994 (GRCm39)	missense	probably damaging	0.99
R5613:Fcgbpl1	UTSW	7	27,842,303 (GRCm39)	intron	probably benign
R5637:Fcgbpl1	UTSW	7	27,852,277 (GRCm39)	missense	probably benign	0.00
R5766:Fcgbpl1	UTSW	7	27,836,754 (GRCm39)	nonsense	probably null
R6174:Fcgbpl1	UTSW	7	27,839,384 (GRCm39)	missense	probably damaging	0.96
R6233:Fcgbpl1	UTSW	7	27,830,885 (GRCm39)	missense	probably damaging	0.99
R6379:Fcgbpl1	UTSW	7	27,857,017 (GRCm39)	missense	probably damaging	1.00
R6442:Fcgbpl1	UTSW	7	27,843,611 (GRCm39)	missense	possibly damaging	0.88
R6478:Fcgbpl1	UTSW	7	27,854,798 (GRCm39)	missense	probably damaging	1.00
R6699:Fcgbpl1	UTSW	7	27,843,793 (GRCm39)	missense	probably damaging	1.00
R6852:Fcgbpl1	UTSW	7	27,846,560 (GRCm39)	missense	probably damaging	1.00
R6883:Fcgbpl1	UTSW	7	27,852,260 (GRCm39)	missense	possibly damaging	0.89
R6902:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6903:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6904:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6992:Fcgbpl1	UTSW	7	27,839,608 (GRCm39)	missense	probably benign	0.04
R7023:Fcgbpl1	UTSW	7	27,839,463 (GRCm39)	nonsense	probably null
R7039:Fcgbpl1	UTSW	7	27,839,573 (GRCm39)	missense	possibly damaging	0.80
R7171:Fcgbpl1	UTSW	7	27,853,944 (GRCm39)	nonsense	probably null
R7282:Fcgbpl1	UTSW	7	27,843,833 (GRCm39)	missense	probably benign	0.02
R7291:Fcgbpl1	UTSW	7	27,839,645 (GRCm39)	missense	probably benign
R7344:Fcgbpl1	UTSW	7	27,852,185 (GRCm39)	missense	possibly damaging	0.46
R7344:Fcgbpl1	UTSW	7	27,839,704 (GRCm39)	missense	possibly damaging	0.79
R7392:Fcgbpl1	UTSW	7	27,863,797 (GRCm39)	missense	possibly damaging	0.83
R7531:Fcgbpl1	UTSW	7	27,839,656 (GRCm39)	missense	probably benign
R7541:Fcgbpl1	UTSW	7	27,843,681 (GRCm39)	nonsense	probably null
R7577:Fcgbpl1	UTSW	7	27,853,848 (GRCm39)	missense	possibly damaging	0.65
R7594:Fcgbpl1	UTSW	7	27,830,885 (GRCm39)	missense	probably damaging	0.99
R7647:Fcgbpl1	UTSW	7	27,839,470 (GRCm39)	missense	probably benign	0.00
R7718:Fcgbpl1	UTSW	7	27,846,626 (GRCm39)	missense	probably damaging	1.00
R7733:Fcgbpl1	UTSW	7	27,839,390 (GRCm39)	missense	probably damaging	1.00
R7737:Fcgbpl1	UTSW	7	27,856,498 (GRCm39)	missense	probably damaging	1.00
R7908:Fcgbpl1	UTSW	7	27,846,921 (GRCm39)	missense	probably benign	0.12
R8013:Fcgbpl1	UTSW	7	27,836,966 (GRCm39)	missense	probably benign	0.14
R8014:Fcgbpl1	UTSW	7	27,836,966 (GRCm39)	missense	probably benign	0.14
R8151:Fcgbpl1	UTSW	7	27,852,766 (GRCm39)	missense	possibly damaging	0.95
R8175:Fcgbpl1	UTSW	7	27,863,873 (GRCm39)	nonsense	probably null
R8254:Fcgbpl1	UTSW	7	27,846,774 (GRCm39)	missense	possibly damaging	0.63
R8345:Fcgbpl1	UTSW	7	27,854,785 (GRCm39)	missense	probably damaging	1.00
R8414:Fcgbpl1	UTSW	7	27,842,158 (GRCm39)	missense	probably damaging	1.00
R8419:Fcgbpl1	UTSW	7	27,843,346 (GRCm39)	missense	probably damaging	1.00
R8496:Fcgbpl1	UTSW	7	27,843,377 (GRCm39)	missense	possibly damaging	0.81
R8691:Fcgbpl1	UTSW	7	27,853,264 (GRCm39)	missense	possibly damaging	0.72
R8785:Fcgbpl1	UTSW	7	27,854,132 (GRCm39)	missense	probably damaging	1.00
R8863:Fcgbpl1	UTSW	7	27,831,006 (GRCm39)	missense	probably damaging	1.00
R8926:Fcgbpl1	UTSW	7	27,853,869 (GRCm39)	missense	probably damaging	1.00
R8950:Fcgbpl1	UTSW	7	27,863,751 (GRCm39)	missense	probably benign	0.32
R9014:Fcgbpl1	UTSW	7	27,854,876 (GRCm39)	missense	probably damaging	1.00
R9045:Fcgbpl1	UTSW	7	27,853,856 (GRCm39)	missense	probably damaging	1.00
R9115:Fcgbpl1	UTSW	7	27,853,754 (GRCm39)	missense	possibly damaging	0.74
R9233:Fcgbpl1	UTSW	7	27,839,519 (GRCm39)	missense	possibly damaging	0.83
R9330:Fcgbpl1	UTSW	7	27,856,410 (GRCm39)	missense	probably benign	0.02
R9426:Fcgbpl1	UTSW	7	27,843,281 (GRCm39)	missense	possibly damaging	0.92
R9477:Fcgbpl1	UTSW	7	27,852,265 (GRCm39)	missense	probably damaging	1.00
R9502:Fcgbpl1	UTSW	7	27,836,891 (GRCm39)	missense	probably benign	0.09
R9505:Fcgbpl1	UTSW	7	27,841,909 (GRCm39)	nonsense	probably null
R9601:Fcgbpl1	UTSW	7	27,853,805 (GRCm39)	missense	possibly damaging	0.78
R9630:Fcgbpl1	UTSW	7	27,836,624 (GRCm39)	missense	probably damaging	1.00
R9632:Fcgbpl1	UTSW	7	27,841,726 (GRCm39)	missense	probably benign
R9673:Fcgbpl1	UTSW	7	27,856,044 (GRCm39)	missense	probably benign	0.25
R9735:Fcgbpl1	UTSW	7	27,856,435 (GRCm39)	missense	probably damaging	1.00
Z1176:Fcgbpl1	UTSW	7	27,854,187 (GRCm39)	missense	probably benign	0.03
Z1176:Fcgbpl1	UTSW	7	27,841,811 (GRCm39)	missense	probably benign	0.06
Z1177:Fcgbpl1	UTSW	7	27,839,323 (GRCm39)	missense	probably benign	0.25
Z1186:Fcgbpl1	UTSW	7	27,856,411 (GRCm39)	missense	probably benign	0.01
Z1186:Fcgbpl1	UTSW	7	27,846,130 (GRCm39)	missense	probably benign	0.00
Z1186:Fcgbpl1	UTSW	7	27,830,997 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- AAGCCATGCAGTACCTCAGC -3'
(R):5'- CCATGAAGCTTGTCACCCTCAG -3'

Sequencing Primer
(F):5'- CCTCACTGGCAATGGACC -3'
(R):5'- GTCACCCTCAGCTCCCAG -3'

Posted On

2018-02-28