|Institutional Source||Beutler Lab|
|Gene Name||RAN binding protein 3|
|Is this an essential gene?||Probably essential (E-score: 0.959)|
|Stock #||R6250 (G1)|
|Chromosomal Location||56673225-56711769 bp(+) (GRCm38)|
|Type of Mutation||intron (3797 bp from exon)|
|DNA Base Change (assembly)||T to G at 56677208 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000002445 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000002445]|
|Predicted Effect||probably null
|Meta Mutation Damage Score||0.9755|
|Coding Region Coverage||
|Validation Efficiency||98% (60/61)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Ranbp3||
(F):5'- CCATCTCAGGCATTCTCAGG -3'
(R):5'- AGATCTTGGTTCCAGGCTGTC -3'
(F):5'- ACTGGGCATTCAGAGTCATC -3'
(R):5'- AGGCTGTCTCTCTCCCAGGAG -3'