Incidental Mutation 'R6254:Plxnd1'
| ID |
505974 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnd1
|
| Ensembl Gene |
ENSMUSG00000030123 |
| Gene Name |
plexin D1 |
| Synonyms |
b2b553Clo, 6230425C21Rik, b2b1863Clo |
| MMRRC Submission |
044371-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R6254 (G1)
|
| Quality Score |
178.009 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
115954811-115995005 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 115977960 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Methionine
at position 614
(V614M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000015511
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000015511]
|
| AlphaFold |
Q3UH93 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000015511
AA Change: V614M
PolyPhen 2
Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000015511
Gene: ENSMUSG00000030123
AA Change: V614M
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
48 |
N/A |
INTRINSIC |
|
Sema
|
61 |
531 |
6.52e-90 |
SMART |
|
PSI
|
550 |
603 |
6.06e-12 |
SMART |
|
PSI
|
703 |
755 |
1.06e-2 |
SMART |
|
Blast:PSI
|
850 |
891 |
9e-20 |
BLAST |
|
IPT
|
892 |
981 |
4.43e-20 |
SMART |
|
IPT
|
982 |
1068 |
6.61e-19 |
SMART |
|
IPT
|
1070 |
1149 |
6.13e-14 |
SMART |
|
transmembrane domain
|
1271 |
1293 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1345 |
1888 |
5e-238 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.2%
- 20x: 94.4%
|
| Validation Efficiency |
100% (82/82) |
| MGI Phenotype |
PHENOTYPE: Homozygous null mice display neonatal lethality, thin-walled atria, and vascular abnormalities including abnormal branchial arch artery development, cardiac outflow tract abnormalities, and reduced vascular smooth muscle around some vessels. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam6b |
A |
T |
12: 113,489,570 (GRCm38) |
L2F |
probably damaging |
Het |
| Ank2 |
T |
A |
3: 126,941,804 (GRCm38) |
|
probably benign |
Het |
| Anpep |
T |
G |
7: 79,839,233 (GRCm38) |
D369A |
probably damaging |
Het |
| App |
T |
C |
16: 84,978,177 (GRCm38) |
E599G |
probably damaging |
Het |
| Asphd1 |
C |
T |
7: 126,948,868 (GRCm38) |
V88I |
probably benign |
Het |
| Atad5 |
A |
T |
11: 80,127,389 (GRCm38) |
I1389F |
probably damaging |
Het |
| Blm |
T |
C |
7: 80,480,342 (GRCm38) |
N950S |
probably benign |
Het |
| Bsn |
A |
T |
9: 108,111,866 (GRCm38) |
M2229K |
probably damaging |
Het |
| Cacna2d2 |
A |
G |
9: 107,509,216 (GRCm38) |
M181V |
probably benign |
Het |
| Cadps2 |
T |
A |
6: 23,329,163 (GRCm38) |
|
probably null |
Het |
| Cdh1 |
T |
A |
8: 106,663,798 (GRCm38) |
V590D |
probably damaging |
Het |
| Cdk5rap2 |
G |
A |
4: 70,364,032 (GRCm38) |
T160M |
probably damaging |
Het |
| Cfap97d2 |
A |
G |
8: 13,706,043 (GRCm38) |
D26G |
possibly damaging |
Het |
| Cfhr4 |
A |
G |
1: 139,754,390 (GRCm38) |
I156T |
probably damaging |
Het |
| Chrna5 |
A |
G |
9: 55,006,456 (GRCm38) |
M325V |
probably benign |
Het |
| Clca3a2 |
A |
G |
3: 144,802,134 (GRCm38) |
I116T |
probably benign |
Het |
| Cyp2c23 |
T |
C |
19: 44,005,463 (GRCm38) |
K488R |
probably benign |
Het |
| Edil3 |
T |
A |
13: 89,319,729 (GRCm38) |
I451N |
probably damaging |
Het |
| Exph5 |
T |
G |
9: 53,372,710 (GRCm38) |
S364A |
possibly damaging |
Het |
| Fam98c |
A |
G |
7: 29,154,517 (GRCm38) |
S209P |
probably damaging |
Het |
| Fat3 |
G |
A |
9: 15,996,145 (GRCm38) |
L2854F |
probably benign |
Het |
| Fbxo38 |
T |
C |
18: 62,505,500 (GRCm38) |
|
probably null |
Het |
| Fermt2 |
T |
C |
14: 45,476,059 (GRCm38) |
D205G |
probably damaging |
Het |
| Fmnl1 |
G |
A |
11: 103,196,315 (GRCm38) |
|
probably benign |
Het |
| Fn3k |
A |
G |
11: 121,435,068 (GRCm38) |
E27G |
probably damaging |
Het |
| Foxj2 |
A |
G |
6: 122,838,139 (GRCm38) |
H378R |
probably damaging |
Het |
| Fubp1 |
A |
G |
3: 152,232,408 (GRCm38) |
K140E |
possibly damaging |
Het |
| Gm7694 |
A |
T |
1: 170,302,534 (GRCm38) |
C98* |
probably null |
Het |
| Golgb1 |
T |
C |
16: 36,913,978 (GRCm38) |
S1196P |
probably damaging |
Het |
| Gpm6a |
G |
A |
8: 55,047,396 (GRCm38) |
|
probably null |
Het |
| Hltf |
T |
A |
3: 20,063,829 (GRCm38) |
N80K |
possibly damaging |
Het |
| Il1rap |
G |
A |
16: 26,695,270 (GRCm38) |
R251H |
probably benign |
Het |
| Ipo7 |
T |
A |
7: 110,049,060 (GRCm38) |
D688E |
probably benign |
Het |
| Itgal |
T |
A |
7: 127,325,203 (GRCm38) |
N897K |
probably damaging |
Het |
| Itsn2 |
A |
G |
12: 4,624,982 (GRCm38) |
|
probably null |
Het |
| Kcnk13 |
A |
G |
12: 99,965,372 (GRCm38) |
|
probably benign |
Het |
| Kdm7a |
A |
G |
6: 39,170,269 (GRCm38) |
L248P |
probably damaging |
Het |
| Kmt2c |
T |
C |
5: 25,349,874 (GRCm38) |
E1254G |
possibly damaging |
Het |
| Ldah |
G |
A |
12: 8,275,912 (GRCm38) |
|
probably benign |
Het |
| Lingo1 |
T |
A |
9: 56,620,087 (GRCm38) |
D406V |
possibly damaging |
Het |
| Lratd2 |
A |
G |
15: 60,823,801 (GRCm38) |
I32T |
probably damaging |
Het |
| Lrriq1 |
A |
T |
10: 103,215,451 (GRCm38) |
V480E |
probably benign |
Het |
| Mtcl1 |
C |
T |
17: 66,358,134 (GRCm38) |
R1142H |
probably benign |
Het |
| Mtmr3 |
G |
A |
11: 4,497,381 (GRCm38) |
Q360* |
probably null |
Het |
| Muc6 |
T |
C |
7: 141,651,115 (GRCm38) |
N252S |
probably benign |
Het |
| Naa20 |
T |
C |
2: 145,903,320 (GRCm38) |
L4P |
probably damaging |
Het |
| Neb |
T |
A |
2: 52,222,961 (GRCm38) |
I4274L |
probably benign |
Het |
| Noa1 |
A |
T |
5: 77,309,669 (GRCm38) |
F130I |
probably benign |
Het |
| Nrg4 |
G |
T |
9: 55,236,512 (GRCm38) |
H87N |
possibly damaging |
Het |
| Or51ai2 |
T |
A |
7: 103,937,534 (GRCm38) |
H51Q |
probably benign |
Het |
| Or5m12 |
T |
A |
2: 85,904,505 (GRCm38) |
Y183F |
probably damaging |
Het |
| P3h3 |
C |
T |
6: 124,845,601 (GRCm38) |
E536K |
probably damaging |
Het |
| Pcdhb11 |
T |
C |
18: 37,421,718 (GRCm38) |
S34P |
probably damaging |
Het |
| Pik3r1 |
T |
C |
13: 101,689,406 (GRCm38) |
T71A |
possibly damaging |
Het |
| Plaur |
T |
A |
7: 24,466,800 (GRCm38) |
C99S |
possibly damaging |
Het |
| Plekha5 |
G |
A |
6: 140,586,436 (GRCm38) |
G501E |
probably damaging |
Het |
| Ppp2r3a |
T |
C |
9: 101,148,587 (GRCm38) |
D307G |
possibly damaging |
Het |
| Prl3d3 |
C |
T |
13: 27,157,470 (GRCm38) |
S28F |
possibly damaging |
Het |
| Prpf40a |
T |
C |
2: 53,157,915 (GRCm38) |
M197V |
probably benign |
Het |
| Ptk7 |
C |
A |
17: 46,572,642 (GRCm38) |
Q832H |
probably damaging |
Het |
| Qser1 |
T |
C |
2: 104,790,090 (GRCm38) |
S126G |
probably benign |
Het |
| Rab3ip |
A |
T |
10: 116,915,867 (GRCm38) |
C332S |
probably damaging |
Het |
| Raly |
C |
A |
2: 154,857,366 (GRCm38) |
T30K |
probably damaging |
Het |
| Rbp2 |
G |
T |
9: 98,490,647 (GRCm38) |
S13I |
probably benign |
Het |
| Rps6ka1 |
C |
T |
4: 133,867,224 (GRCm38) |
M159I |
possibly damaging |
Het |
| Rufy3 |
C |
T |
5: 88,584,309 (GRCm38) |
T57I |
probably benign |
Het |
| Samd4 |
A |
G |
14: 47,016,631 (GRCm38) |
D184G |
probably damaging |
Het |
| Slc35f3 |
T |
C |
8: 126,321,094 (GRCm38) |
C58R |
possibly damaging |
Het |
| Smarca4 |
T |
C |
9: 21,699,877 (GRCm38) |
I1467T |
probably damaging |
Het |
| Spag17 |
T |
G |
3: 100,065,585 (GRCm38) |
I1371S |
probably benign |
Het |
| Sptan1 |
T |
C |
2: 30,007,549 (GRCm38) |
L1228P |
possibly damaging |
Het |
| Stk31 |
C |
T |
6: 49,421,697 (GRCm38) |
A344V |
probably benign |
Het |
| Supt16 |
A |
G |
14: 52,170,834 (GRCm38) |
W885R |
probably damaging |
Het |
| Tdrd9 |
T |
A |
12: 112,025,900 (GRCm38) |
|
probably null |
Het |
| Tmod1 |
A |
G |
4: 46,078,469 (GRCm38) |
|
probably null |
Het |
| Tnfsf13 |
A |
C |
11: 69,684,483 (GRCm38) |
|
probably null |
Het |
| Trim75 |
C |
A |
8: 64,983,442 (GRCm38) |
E119* |
probably null |
Het |
| Wdr6 |
T |
C |
9: 108,574,911 (GRCm38) |
Y591C |
probably damaging |
Het |
| Wdr86 |
C |
T |
5: 24,718,283 (GRCm38) |
R137H |
probably benign |
Het |
| Ythdf1 |
T |
A |
2: 180,911,150 (GRCm38) |
Y424F |
probably damaging |
Het |
| Zfp984 |
G |
T |
4: 147,756,186 (GRCm38) |
S69R |
possibly damaging |
Het |
| Zyg11a |
A |
G |
4: 108,181,794 (GRCm38) |
F743L |
probably damaging |
Het |
|
| Other mutations in Plxnd1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00764:Plxnd1
|
APN |
6 |
115,967,972 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
IGL01099:Plxnd1
|
APN |
6 |
115,969,945 (GRCm38) |
missense |
probably benign |
|
|
IGL01323:Plxnd1
|
APN |
6 |
115,966,799 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
IGL01382:Plxnd1
|
APN |
6 |
115,960,527 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01786:Plxnd1
|
APN |
6 |
115,959,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02244:Plxnd1
|
APN |
6 |
115,978,257 (GRCm38) |
missense |
probably benign |
0.39 |
|
IGL02272:Plxnd1
|
APN |
6 |
115,993,628 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02293:Plxnd1
|
APN |
6 |
115,963,913 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02465:Plxnd1
|
APN |
6 |
115,955,742 (GRCm38) |
makesense |
probably null |
|
|
IGL02873:Plxnd1
|
APN |
6 |
115,959,976 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03209:Plxnd1
|
APN |
6 |
115,962,357 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Hiss
|
UTSW |
6 |
115,969,929 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
murmer
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
mutter
|
UTSW |
6 |
115,968,044 (GRCm38) |
missense |
probably benign |
0.27 |
|
rattle
|
UTSW |
6 |
115,959,794 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0357:Plxnd1
|
UTSW |
6 |
115,969,460 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0646:Plxnd1
|
UTSW |
6 |
115,958,699 (GRCm38) |
splice site |
probably benign |
|
|
R0648:Plxnd1
|
UTSW |
6 |
115,994,001 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R0718:Plxnd1
|
UTSW |
6 |
115,966,638 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R1116:Plxnd1
|
UTSW |
6 |
115,967,005 (GRCm38) |
splice site |
probably null |
|
|
R1292:Plxnd1
|
UTSW |
6 |
115,962,683 (GRCm38) |
unclassified |
probably benign |
|
|
R1715:Plxnd1
|
UTSW |
6 |
115,968,681 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1760:Plxnd1
|
UTSW |
6 |
115,967,779 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1799:Plxnd1
|
UTSW |
6 |
115,994,057 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1817:Plxnd1
|
UTSW |
6 |
115,980,601 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R1848:Plxnd1
|
UTSW |
6 |
115,966,546 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1851:Plxnd1
|
UTSW |
6 |
115,963,914 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1864:Plxnd1
|
UTSW |
6 |
115,969,441 (GRCm38) |
splice site |
probably null |
|
|
R1865:Plxnd1
|
UTSW |
6 |
115,969,441 (GRCm38) |
splice site |
probably null |
|
|
R1875:Plxnd1
|
UTSW |
6 |
115,978,084 (GRCm38) |
splice site |
probably null |
|
|
R1899:Plxnd1
|
UTSW |
6 |
115,969,363 (GRCm38) |
missense |
probably benign |
|
|
R1913:Plxnd1
|
UTSW |
6 |
115,978,017 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R1970:Plxnd1
|
UTSW |
6 |
115,962,517 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2007:Plxnd1
|
UTSW |
6 |
115,967,255 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2134:Plxnd1
|
UTSW |
6 |
115,957,548 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2202:Plxnd1
|
UTSW |
6 |
115,962,764 (GRCm38) |
missense |
probably benign |
0.45 |
|
R2230:Plxnd1
|
UTSW |
6 |
115,964,144 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2267:Plxnd1
|
UTSW |
6 |
115,962,743 (GRCm38) |
missense |
probably benign |
0.29 |
|
R2427:Plxnd1
|
UTSW |
6 |
115,967,748 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4108:Plxnd1
|
UTSW |
6 |
115,959,315 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4233:Plxnd1
|
UTSW |
6 |
115,965,953 (GRCm38) |
missense |
probably benign |
0.30 |
|
R4280:Plxnd1
|
UTSW |
6 |
115,956,095 (GRCm38) |
splice site |
probably null |
|
|
R4280:Plxnd1
|
UTSW |
6 |
115,956,094 (GRCm38) |
splice site |
probably benign |
|
|
R4346:Plxnd1
|
UTSW |
6 |
115,977,980 (GRCm38) |
missense |
probably benign |
0.16 |
|
R4439:Plxnd1
|
UTSW |
6 |
115,993,976 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4572:Plxnd1
|
UTSW |
6 |
115,955,756 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4576:Plxnd1
|
UTSW |
6 |
115,968,044 (GRCm38) |
missense |
probably benign |
0.27 |
|
R4599:Plxnd1
|
UTSW |
6 |
115,994,276 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4614:Plxnd1
|
UTSW |
6 |
115,972,525 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R4700:Plxnd1
|
UTSW |
6 |
115,958,615 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4705:Plxnd1
|
UTSW |
6 |
115,958,620 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4806:Plxnd1
|
UTSW |
6 |
115,960,855 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4944:Plxnd1
|
UTSW |
6 |
115,955,765 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4977:Plxnd1
|
UTSW |
6 |
115,994,376 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5069:Plxnd1
|
UTSW |
6 |
115,965,901 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5155:Plxnd1
|
UTSW |
6 |
115,958,988 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5460:Plxnd1
|
UTSW |
6 |
115,957,648 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5729:Plxnd1
|
UTSW |
6 |
115,965,877 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5909:Plxnd1
|
UTSW |
6 |
115,968,688 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5992:Plxnd1
|
UTSW |
6 |
115,967,787 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R6129:Plxnd1
|
UTSW |
6 |
115,978,174 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6273:Plxnd1
|
UTSW |
6 |
115,978,492 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6310:Plxnd1
|
UTSW |
6 |
115,976,736 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R6732:Plxnd1
|
UTSW |
6 |
115,969,929 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R6857:Plxnd1
|
UTSW |
6 |
115,993,763 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7243:Plxnd1
|
UTSW |
6 |
115,972,507 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7282:Plxnd1
|
UTSW |
6 |
115,960,837 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7632:Plxnd1
|
UTSW |
6 |
115,976,639 (GRCm38) |
missense |
probably benign |
|
|
R7699:Plxnd1
|
UTSW |
6 |
115,959,794 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7915:Plxnd1
|
UTSW |
6 |
115,966,918 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8090:Plxnd1
|
UTSW |
6 |
115,956,617 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8382:Plxnd1
|
UTSW |
6 |
115,972,472 (GRCm38) |
missense |
probably benign |
|
|
R8507:Plxnd1
|
UTSW |
6 |
115,966,905 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R8539:Plxnd1
|
UTSW |
6 |
115,962,807 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R8548:Plxnd1
|
UTSW |
6 |
115,957,597 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8963:Plxnd1
|
UTSW |
6 |
115,972,545 (GRCm38) |
nonsense |
probably null |
|
|
R9119:Plxnd1
|
UTSW |
6 |
115,955,871 (GRCm38) |
splice site |
probably benign |
|
|
R9177:Plxnd1
|
UTSW |
6 |
115,966,508 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9182:Plxnd1
|
UTSW |
6 |
115,993,785 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9185:Plxnd1
|
UTSW |
6 |
115,957,565 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9226:Plxnd1
|
UTSW |
6 |
115,957,563 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9433:Plxnd1
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9449:Plxnd1
|
UTSW |
6 |
115,955,769 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9451:Plxnd1
|
UTSW |
6 |
115,963,316 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R9599:Plxnd1
|
UTSW |
6 |
115,963,313 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R9627:Plxnd1
|
UTSW |
6 |
115,963,313 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R9644:Plxnd1
|
UTSW |
6 |
115,963,313 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R9672:Plxnd1
|
UTSW |
6 |
115,963,313 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
X0024:Plxnd1
|
UTSW |
6 |
115,963,310 (GRCm38) |
missense |
probably benign |
0.02 |
|
X0026:Plxnd1
|
UTSW |
6 |
115,966,784 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
Z1088:Plxnd1
|
UTSW |
6 |
115,967,510 (GRCm38) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCATGGTCCTAACTGTTGACTAGG -3'
(R):5'- CTACTGTGGTTGGTGCACTC -3'
Sequencing Primer
(F):5'- CCTAACTGTTGACTAGGTCTTGCAAG -3'
(R):5'- TTGGTGCACTCTGGAGACC -3'
|
| Posted On |
2018-02-28 |
Incidental Mutation