Incidental Mutation 'R6291:Plxnc1'
| ID |
508447 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnc1
|
| Ensembl Gene |
ENSMUSG00000074785 |
| Gene Name |
plexin C1 |
| Synonyms |
CD232, vespr, 2510048K12Rik |
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.474)
|
| Stock # |
R6291 (G1)
|
| Quality Score |
213.009 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
94790866-94944835 bp(-) (GRCm38) |
| Type of Mutation |
splice site (6 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 94833642 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000096939
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099337]
|
| AlphaFold |
Q9QZC2 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000099337
|
| SMART Domains |
Protein: ENSMUSP00000096939
Gene: ENSMUSG00000074785
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
34 |
N/A |
INTRINSIC |
|
Pfam:Sema
|
87 |
431 |
5.5e-10 |
PFAM |
|
PSI
|
454 |
507 |
5.28e-12 |
SMART |
|
PSI
|
590 |
634 |
1.07e-3 |
SMART |
|
Pfam:TIG
|
665 |
752 |
3.7e-9 |
PFAM |
|
IPT
|
755 |
847 |
5.14e-7 |
SMART |
|
IPT
|
849 |
954 |
1.8e-2 |
SMART |
|
low complexity region
|
978 |
997 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1018 |
1541 |
1.4e-199 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000180514
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000218839
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.6%
- 20x: 96.3%
|
| Validation Efficiency |
98% (86/88) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal neuron morphology and migration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc12 |
C |
T |
8: 86,566,544 (GRCm38) |
G5D |
possibly damaging |
Het |
| Adamts9 |
T |
C |
6: 92,890,120 (GRCm38) |
K95R |
probably damaging |
Het |
| Adap1 |
G |
T |
5: 139,273,491 (GRCm38) |
L314M |
probably benign |
Het |
| Alkbh1 |
T |
A |
12: 87,429,094 (GRCm38) |
E306V |
possibly damaging |
Het |
| Alpk2 |
T |
A |
18: 65,305,901 (GRCm38) |
D1274V |
possibly damaging |
Het |
| Ankrd31 |
A |
C |
13: 96,878,238 (GRCm38) |
K1188N |
possibly damaging |
Het |
| Aox2 |
T |
A |
1: 58,330,806 (GRCm38) |
M759K |
probably damaging |
Het |
| Atp13a3 |
T |
A |
16: 30,336,243 (GRCm38) |
D961V |
probably damaging |
Het |
| Bcl11a |
G |
A |
11: 24,158,321 (GRCm38) |
G100R |
probably damaging |
Het |
| Bpifc |
G |
A |
10: 85,976,258 (GRCm38) |
A362V |
probably damaging |
Het |
| Btaf1 |
C |
T |
19: 36,973,008 (GRCm38) |
T546I |
probably benign |
Het |
| Casd1 |
C |
A |
6: 4,619,834 (GRCm38) |
P193Q |
probably damaging |
Het |
| Cdhr1 |
T |
C |
14: 37,089,465 (GRCm38) |
T230A |
probably benign |
Het |
| Celsr3 |
T |
G |
9: 108,828,842 (GRCm38) |
D841E |
probably damaging |
Het |
| Cenpj |
T |
C |
14: 56,551,976 (GRCm38) |
D872G |
probably benign |
Het |
| Cep95 |
G |
T |
11: 106,815,596 (GRCm38) |
A559S |
probably damaging |
Het |
| Chpt1 |
A |
T |
10: 88,475,444 (GRCm38) |
C62* |
probably null |
Het |
| Cspg4b |
T |
A |
13: 113,320,447 (GRCm38) |
I1009N |
possibly damaging |
Het |
| Cspp1 |
A |
G |
1: 10,064,334 (GRCm38) |
K103R |
probably damaging |
Het |
| Ctla4 |
T |
C |
1: 60,912,678 (GRCm38) |
V122A |
probably benign |
Het |
| Cyp3a11 |
A |
G |
5: 145,862,427 (GRCm38) |
F317L |
possibly damaging |
Het |
| Daam1 |
T |
C |
12: 71,946,251 (GRCm38) |
L338P |
unknown |
Het |
| Dcc |
T |
A |
18: 71,682,167 (GRCm38) |
I379L |
probably benign |
Het |
| Dennd2c |
C |
A |
3: 103,131,609 (GRCm38) |
C24* |
probably null |
Het |
| Dnai3 |
G |
A |
3: 146,066,893 (GRCm38) |
S466L |
probably benign |
Het |
| Dnajc12 |
A |
G |
10: 63,397,274 (GRCm38) |
I65V |
probably benign |
Het |
| Dock3 |
T |
A |
9: 106,908,432 (GRCm38) |
M208L |
probably benign |
Het |
| Dsg1b |
T |
C |
18: 20,404,791 (GRCm38) |
I588T |
possibly damaging |
Het |
| Eif1b |
T |
C |
9: 120,494,140 (GRCm38) |
L22S |
probably benign |
Het |
| Ep300 |
T |
A |
15: 81,648,507 (GRCm38) |
S1649T |
unknown |
Het |
| Eps15 |
CAAA |
CAA |
4: 109,305,703 (GRCm38) |
|
probably null |
Het |
| Ercc6 |
A |
T |
14: 32,569,986 (GRCm38) |
E1102D |
probably benign |
Het |
| Gsdmc3 |
T |
C |
15: 63,860,241 (GRCm38) |
N312S |
probably benign |
Het |
| Guca2b |
A |
T |
4: 119,657,693 (GRCm38) |
L57Q |
probably damaging |
Het |
| Heatr5b |
G |
T |
17: 78,762,097 (GRCm38) |
H1740Q |
probably benign |
Het |
| Hecw1 |
G |
A |
13: 14,523,007 (GRCm38) |
|
probably benign |
Het |
| Icam5 |
A |
G |
9: 21,036,921 (GRCm38) |
H675R |
probably benign |
Het |
| Il18rap |
T |
C |
1: 40,524,889 (GRCm38) |
F56L |
probably benign |
Het |
| Iqgap3 |
T |
A |
3: 88,089,730 (GRCm38) |
|
probably null |
Het |
| Itsn1 |
T |
C |
16: 91,868,096 (GRCm38) |
|
probably benign |
Het |
| Jakmip3 |
A |
T |
7: 139,020,856 (GRCm38) |
D315V |
probably damaging |
Het |
| Kif24 |
A |
G |
4: 41,413,959 (GRCm38) |
Y328H |
probably damaging |
Het |
| Kmt2a |
A |
T |
9: 44,832,874 (GRCm38) |
|
probably benign |
Het |
| Kng1 |
A |
G |
16: 23,079,725 (GRCm38) |
E625G |
probably damaging |
Het |
| Man2b1 |
C |
T |
8: 85,097,046 (GRCm38) |
T973I |
probably benign |
Het |
| Masp2 |
G |
A |
4: 148,602,753 (GRCm38) |
V31M |
probably damaging |
Het |
| Myo18b |
C |
T |
5: 112,865,735 (GRCm38) |
R785H |
possibly damaging |
Het |
| Naa15 |
G |
A |
3: 51,442,791 (GRCm38) |
G103D |
probably damaging |
Het |
| Or4f15 |
A |
G |
2: 111,983,624 (GRCm38) |
V150A |
probably benign |
Het |
| Or5m11b |
A |
G |
2: 85,975,582 (GRCm38) |
Y113C |
probably damaging |
Het |
| Or7e177 |
T |
A |
9: 20,300,603 (GRCm38) |
D134E |
probably damaging |
Het |
| Papln |
A |
G |
12: 83,783,015 (GRCm38) |
N970S |
probably benign |
Het |
| Pick1 |
T |
A |
15: 79,251,728 (GRCm38) |
|
probably null |
Het |
| Pigr |
A |
C |
1: 130,841,761 (GRCm38) |
D103A |
probably benign |
Het |
| Plekhf1 |
A |
C |
7: 38,221,605 (GRCm38) |
F180V |
possibly damaging |
Het |
| Polr3f |
A |
G |
2: 144,534,388 (GRCm38) |
I136V |
probably damaging |
Het |
| Ppp2r2c |
T |
C |
5: 36,940,124 (GRCm38) |
M218T |
possibly damaging |
Het |
| Prox2 |
C |
T |
12: 85,089,646 (GRCm38) |
V466I |
probably damaging |
Het |
| Prrc2a |
G |
A |
17: 35,154,933 (GRCm38) |
L1479F |
probably damaging |
Het |
| Rbm24 |
T |
A |
13: 46,421,837 (GRCm38) |
|
probably null |
Het |
| Rcc1l |
A |
T |
5: 134,166,721 (GRCm38) |
|
probably null |
Het |
| Ripk4 |
A |
C |
16: 97,755,123 (GRCm38) |
L140R |
probably damaging |
Het |
| Rmnd1 |
A |
T |
10: 4,422,135 (GRCm38) |
L188Q |
probably damaging |
Het |
| Rnf170 |
C |
T |
8: 26,140,964 (GRCm38) |
P249S |
probably damaging |
Het |
| Rras |
A |
G |
7: 45,018,171 (GRCm38) |
|
probably null |
Het |
| Rsf1 |
G |
A |
7: 97,579,910 (GRCm38) |
|
probably benign |
Het |
| Scn7a |
T |
A |
2: 66,700,114 (GRCm38) |
D629V |
probably damaging |
Het |
| Sipa1l3 |
A |
G |
7: 29,388,133 (GRCm38) |
S556P |
probably damaging |
Het |
| Smarca2 |
C |
T |
19: 26,630,892 (GRCm38) |
A117V |
probably damaging |
Het |
| Snca |
C |
T |
6: 60,815,718 (GRCm38) |
A69T |
probably damaging |
Het |
| Snx2 |
T |
C |
18: 53,209,665 (GRCm38) |
|
probably null |
Het |
| Spp1 |
T |
A |
5: 104,439,376 (GRCm38) |
S109T |
possibly damaging |
Het |
| Stoml3 |
T |
C |
3: 53,507,516 (GRCm38) |
L243P |
probably damaging |
Het |
| Susd2 |
A |
G |
10: 75,637,574 (GRCm38) |
F789L |
possibly damaging |
Het |
| Sycp1 |
A |
G |
3: 102,908,961 (GRCm38) |
M419T |
probably damaging |
Het |
| Thoc1 |
T |
C |
18: 9,993,330 (GRCm38) |
V563A |
probably benign |
Het |
| Tmprss11g |
T |
C |
5: 86,487,422 (GRCm38) |
I398V |
probably damaging |
Het |
| Tox3 |
A |
G |
8: 90,248,938 (GRCm38) |
L355P |
probably damaging |
Het |
| Tpp1 |
A |
G |
7: 105,747,016 (GRCm38) |
I492T |
probably benign |
Het |
| Trim21 |
A |
T |
7: 102,564,082 (GRCm38) |
L3Q |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,914,294 (GRCm38) |
|
probably benign |
Het |
| Ttn |
A |
C |
2: 76,907,736 (GRCm38) |
V4153G |
probably benign |
Het |
| Unc80 |
A |
G |
1: 66,521,597 (GRCm38) |
E828G |
possibly damaging |
Het |
| Vav3 |
A |
G |
3: 109,508,854 (GRCm38) |
N263S |
possibly damaging |
Het |
| Vmn1r183 |
A |
C |
7: 24,055,557 (GRCm38) |
T262P |
possibly damaging |
Het |
| Vmn2r67 |
G |
A |
7: 85,149,934 (GRCm38) |
P522S |
possibly damaging |
Het |
| Vps35 |
T |
A |
8: 85,299,457 (GRCm38) |
M1L |
probably benign |
Het |
| Xpo7 |
A |
T |
14: 70,704,690 (GRCm38) |
L79* |
probably null |
Het |
| Zc3h14 |
G |
A |
12: 98,759,828 (GRCm38) |
R324H |
probably damaging |
Het |
| Zfp330 |
T |
C |
8: 82,772,984 (GRCm38) |
T6A |
probably damaging |
Het |
| Zfp948 |
T |
A |
17: 21,587,024 (GRCm38) |
H159Q |
unknown |
Het |
|
| Other mutations in Plxnc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00843:Plxnc1
|
APN |
10 |
94,847,549 (GRCm38) |
missense |
probably benign |
0.25 |
|
IGL01285:Plxnc1
|
APN |
10 |
94,799,368 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01867:Plxnc1
|
APN |
10 |
94,798,146 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
IGL01994:Plxnc1
|
APN |
10 |
94,849,939 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02083:Plxnc1
|
APN |
10 |
94,922,725 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
IGL02250:Plxnc1
|
APN |
10 |
94,871,031 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02429:Plxnc1
|
APN |
10 |
94,882,591 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02752:Plxnc1
|
APN |
10 |
94,794,680 (GRCm38) |
splice site |
probably null |
|
|
IGL02973:Plxnc1
|
APN |
10 |
94,810,684 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0230:Plxnc1
|
UTSW |
10 |
94,799,347 (GRCm38) |
missense |
probably benign |
0.07 |
|
R0265:Plxnc1
|
UTSW |
10 |
94,813,129 (GRCm38) |
missense |
probably benign |
0.14 |
|
R0271:Plxnc1
|
UTSW |
10 |
94,837,918 (GRCm38) |
missense |
probably null |
1.00 |
|
R0299:Plxnc1
|
UTSW |
10 |
94,849,821 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0361:Plxnc1
|
UTSW |
10 |
94,865,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0441:Plxnc1
|
UTSW |
10 |
94,796,482 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0558:Plxnc1
|
UTSW |
10 |
94,837,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0617:Plxnc1
|
UTSW |
10 |
94,799,368 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0671:Plxnc1
|
UTSW |
10 |
94,799,332 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R0692:Plxnc1
|
UTSW |
10 |
94,837,500 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0751:Plxnc1
|
UTSW |
10 |
94,831,333 (GRCm38) |
splice site |
probably benign |
|
|
R1184:Plxnc1
|
UTSW |
10 |
94,831,333 (GRCm38) |
splice site |
probably benign |
|
|
R1260:Plxnc1
|
UTSW |
10 |
94,831,365 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1680:Plxnc1
|
UTSW |
10 |
94,841,551 (GRCm38) |
missense |
probably benign |
0.14 |
|
R1746:Plxnc1
|
UTSW |
10 |
94,844,179 (GRCm38) |
splice site |
probably null |
|
|
R1750:Plxnc1
|
UTSW |
10 |
94,799,497 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1751:Plxnc1
|
UTSW |
10 |
94,849,815 (GRCm38) |
unclassified |
probably benign |
|
|
R1768:Plxnc1
|
UTSW |
10 |
94,844,322 (GRCm38) |
missense |
probably benign |
0.05 |
|
R1876:Plxnc1
|
UTSW |
10 |
94,866,941 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R2004:Plxnc1
|
UTSW |
10 |
94,852,622 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R2031:Plxnc1
|
UTSW |
10 |
94,943,667 (GRCm38) |
missense |
probably benign |
0.26 |
|
R2184:Plxnc1
|
UTSW |
10 |
94,944,269 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2437:Plxnc1
|
UTSW |
10 |
94,906,533 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2927:Plxnc1
|
UTSW |
10 |
94,793,292 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R3001:Plxnc1
|
UTSW |
10 |
94,793,218 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R3002:Plxnc1
|
UTSW |
10 |
94,793,218 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R3003:Plxnc1
|
UTSW |
10 |
94,793,218 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R3441:Plxnc1
|
UTSW |
10 |
94,871,010 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3849:Plxnc1
|
UTSW |
10 |
94,794,432 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3884:Plxnc1
|
UTSW |
10 |
94,910,687 (GRCm38) |
splice site |
probably null |
|
|
R4004:Plxnc1
|
UTSW |
10 |
94,794,597 (GRCm38) |
nonsense |
probably null |
|
|
R4679:Plxnc1
|
UTSW |
10 |
94,794,444 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4730:Plxnc1
|
UTSW |
10 |
94,867,468 (GRCm38) |
intron |
probably benign |
|
|
R4937:Plxnc1
|
UTSW |
10 |
94,841,473 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5068:Plxnc1
|
UTSW |
10 |
94,799,377 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R5345:Plxnc1
|
UTSW |
10 |
94,849,969 (GRCm38) |
missense |
probably benign |
0.26 |
|
R5397:Plxnc1
|
UTSW |
10 |
94,843,752 (GRCm38) |
missense |
probably benign |
0.08 |
|
R5416:Plxnc1
|
UTSW |
10 |
94,837,554 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5485:Plxnc1
|
UTSW |
10 |
94,922,742 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5543:Plxnc1
|
UTSW |
10 |
94,864,774 (GRCm38) |
missense |
probably benign |
|
|
R5826:Plxnc1
|
UTSW |
10 |
94,799,473 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6007:Plxnc1
|
UTSW |
10 |
94,793,290 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R6018:Plxnc1
|
UTSW |
10 |
94,943,848 (GRCm38) |
missense |
probably benign |
0.21 |
|
R6052:Plxnc1
|
UTSW |
10 |
94,943,773 (GRCm38) |
missense |
probably benign |
0.13 |
|
R6653:Plxnc1
|
UTSW |
10 |
94,943,876 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6984:Plxnc1
|
UTSW |
10 |
94,831,530 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7086:Plxnc1
|
UTSW |
10 |
94,831,435 (GRCm38) |
missense |
probably benign |
|
|
R7401:Plxnc1
|
UTSW |
10 |
94,871,005 (GRCm38) |
missense |
probably benign |
|
|
R7727:Plxnc1
|
UTSW |
10 |
94,944,109 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7789:Plxnc1
|
UTSW |
10 |
94,794,477 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7803:Plxnc1
|
UTSW |
10 |
94,943,515 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7809:Plxnc1
|
UTSW |
10 |
94,794,440 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7882:Plxnc1
|
UTSW |
10 |
94,843,836 (GRCm38) |
missense |
probably benign |
|
|
R8103:Plxnc1
|
UTSW |
10 |
94,871,082 (GRCm38) |
missense |
probably benign |
|
|
R8226:Plxnc1
|
UTSW |
10 |
94,833,368 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R8273:Plxnc1
|
UTSW |
10 |
94,813,243 (GRCm38) |
missense |
probably benign |
0.14 |
|
R8299:Plxnc1
|
UTSW |
10 |
94,827,179 (GRCm38) |
missense |
probably benign |
0.35 |
|
R8392:Plxnc1
|
UTSW |
10 |
94,801,490 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R8758:Plxnc1
|
UTSW |
10 |
94,922,745 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R8806:Plxnc1
|
UTSW |
10 |
94,799,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8882:Plxnc1
|
UTSW |
10 |
94,841,566 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8893:Plxnc1
|
UTSW |
10 |
94,849,847 (GRCm38) |
missense |
probably benign |
0.35 |
|
R8956:Plxnc1
|
UTSW |
10 |
94,910,586 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9040:Plxnc1
|
UTSW |
10 |
94,943,517 (GRCm38) |
nonsense |
probably null |
|
|
R9102:Plxnc1
|
UTSW |
10 |
94,827,245 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9225:Plxnc1
|
UTSW |
10 |
94,793,199 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9324:Plxnc1
|
UTSW |
10 |
94,944,823 (GRCm38) |
start gained |
probably benign |
|
|
R9368:Plxnc1
|
UTSW |
10 |
94,864,737 (GRCm38) |
nonsense |
probably null |
|
|
R9375:Plxnc1
|
UTSW |
10 |
94,813,231 (GRCm38) |
missense |
probably benign |
0.20 |
|
R9430:Plxnc1
|
UTSW |
10 |
94,922,682 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9460:Plxnc1
|
UTSW |
10 |
94,865,033 (GRCm38) |
missense |
probably benign |
|
|
R9498:Plxnc1
|
UTSW |
10 |
94,813,142 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
RF003:Plxnc1
|
UTSW |
10 |
94,794,444 (GRCm38) |
missense |
probably damaging |
1.00 |
|
RF045:Plxnc1
|
UTSW |
10 |
94,865,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
RF046:Plxnc1
|
UTSW |
10 |
94,865,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
RF047:Plxnc1
|
UTSW |
10 |
94,865,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0024:Plxnc1
|
UTSW |
10 |
94,864,715 (GRCm38) |
critical splice donor site |
probably null |
|
|
Z1176:Plxnc1
|
UTSW |
10 |
94,865,029 (GRCm38) |
missense |
probably benign |
0.16 |
|
| Predicted Primers |
PCR Primer
(F):5'- TATGAGGGCATCCAAGGCTG -3'
(R):5'- ACCAAGGGCTCTTCAGATTAGC -3'
Sequencing Primer
(F):5'- TGATAATATAGCTCAGGACCATACG -3'
(R):5'- GGGCTCTTCAGATTAGCAAATAGC -3'
|
| Posted On |
2018-03-15 |
Incidental Mutation