Incidental Mutation 'R6291:Hecw1'
| ID |
508455 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Hecw1
|
| Ensembl Gene |
ENSMUSG00000021301 |
| Gene Name |
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| Synonyms |
NEDL1, E130207I19Rik |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6291 (G1)
|
| Quality Score |
112.008 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
14401023-14697813 bp(-) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
G to A
at 14697592 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000152688
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000110516]
[ENSMUST00000221274]
[ENSMUST00000223189]
[ENSMUST00000223550]
|
| AlphaFold |
Q8K4P8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110516
|
| SMART Domains |
Protein: ENSMUSP00000106145
Gene: ENSMUSG00000021301
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:HECW_N
|
65 |
184 |
6.5e-62 |
PFAM |
|
C2
|
206 |
317 |
1.02e-12 |
SMART |
|
low complexity region
|
463 |
477 |
N/A |
INTRINSIC |
|
low complexity region
|
497 |
512 |
N/A |
INTRINSIC |
|
low complexity region
|
577 |
598 |
N/A |
INTRINSIC |
|
low complexity region
|
677 |
704 |
N/A |
INTRINSIC |
|
low complexity region
|
731 |
745 |
N/A |
INTRINSIC |
|
WW
|
827 |
859 |
8.66e-13 |
SMART |
|
coiled coil region
|
873 |
898 |
N/A |
INTRINSIC |
|
low complexity region
|
917 |
930 |
N/A |
INTRINSIC |
|
WW
|
1017 |
1049 |
5.59e-7 |
SMART |
|
Blast:HECTc
|
1137 |
1192 |
3e-26 |
BLAST |
|
low complexity region
|
1193 |
1208 |
N/A |
INTRINSIC |
|
low complexity region
|
1212 |
1223 |
N/A |
INTRINSIC |
|
HECTc
|
1267 |
1604 |
1.36e-185 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000220479
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000221274
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000221863
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000222432
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000222904
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000223189
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000223283
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000223317
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000223550
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.6%
- 20x: 96.3%
|
| Validation Efficiency |
98% (86/88) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc12 |
C |
T |
8: 87,293,173 (GRCm39) |
G5D |
possibly damaging |
Het |
| Adamts9 |
T |
C |
6: 92,867,101 (GRCm39) |
K95R |
probably damaging |
Het |
| Adap1 |
G |
T |
5: 139,259,246 (GRCm39) |
L314M |
probably benign |
Het |
| Alkbh1 |
T |
A |
12: 87,475,864 (GRCm39) |
E306V |
possibly damaging |
Het |
| Alpk2 |
T |
A |
18: 65,438,972 (GRCm39) |
D1274V |
possibly damaging |
Het |
| Ankrd31 |
A |
C |
13: 97,014,746 (GRCm39) |
K1188N |
possibly damaging |
Het |
| Aox1 |
T |
A |
1: 58,369,965 (GRCm39) |
M759K |
probably damaging |
Het |
| Atp13a3 |
T |
A |
16: 30,155,061 (GRCm39) |
D961V |
probably damaging |
Het |
| Bcl11a |
G |
A |
11: 24,108,321 (GRCm39) |
G100R |
probably damaging |
Het |
| Bpifc |
G |
A |
10: 85,812,122 (GRCm39) |
A362V |
probably damaging |
Het |
| Btaf1 |
C |
T |
19: 36,950,408 (GRCm39) |
T546I |
probably benign |
Het |
| Casd1 |
C |
A |
6: 4,619,834 (GRCm39) |
P193Q |
probably damaging |
Het |
| Cdhr1 |
T |
C |
14: 36,811,422 (GRCm39) |
T230A |
probably benign |
Het |
| Celsr3 |
T |
G |
9: 108,706,041 (GRCm39) |
D841E |
probably damaging |
Het |
| Cenpj |
T |
C |
14: 56,789,433 (GRCm39) |
D872G |
probably benign |
Het |
| Cep95 |
G |
T |
11: 106,706,422 (GRCm39) |
A559S |
probably damaging |
Het |
| Chpt1 |
A |
T |
10: 88,311,306 (GRCm39) |
C62* |
probably null |
Het |
| Cspg4b |
T |
A |
13: 113,456,981 (GRCm39) |
I1009N |
possibly damaging |
Het |
| Cspp1 |
A |
G |
1: 10,134,559 (GRCm39) |
K103R |
probably damaging |
Het |
| Ctla4 |
T |
C |
1: 60,951,837 (GRCm39) |
V122A |
probably benign |
Het |
| Cyp3a11 |
A |
G |
5: 145,799,237 (GRCm39) |
F317L |
possibly damaging |
Het |
| Daam1 |
T |
C |
12: 71,993,025 (GRCm39) |
L338P |
unknown |
Het |
| Dcc |
T |
A |
18: 71,815,238 (GRCm39) |
I379L |
probably benign |
Het |
| Dennd2c |
C |
A |
3: 103,038,925 (GRCm39) |
C24* |
probably null |
Het |
| Dnai3 |
G |
A |
3: 145,772,648 (GRCm39) |
S466L |
probably benign |
Het |
| Dnajc12 |
A |
G |
10: 63,233,053 (GRCm39) |
I65V |
probably benign |
Het |
| Dock3 |
T |
A |
9: 106,785,631 (GRCm39) |
M208L |
probably benign |
Het |
| Dsg1b |
T |
C |
18: 20,537,848 (GRCm39) |
I588T |
possibly damaging |
Het |
| Eif1b |
T |
C |
9: 120,323,206 (GRCm39) |
L22S |
probably benign |
Het |
| Ep300 |
T |
A |
15: 81,532,708 (GRCm39) |
S1649T |
unknown |
Het |
| Eps15 |
CAAA |
CAA |
4: 109,162,900 (GRCm39) |
|
probably null |
Het |
| Ercc6 |
A |
T |
14: 32,291,943 (GRCm39) |
E1102D |
probably benign |
Het |
| Gsdmc3 |
T |
C |
15: 63,732,090 (GRCm39) |
N312S |
probably benign |
Het |
| Guca2b |
A |
T |
4: 119,514,890 (GRCm39) |
L57Q |
probably damaging |
Het |
| Heatr5b |
G |
T |
17: 79,069,526 (GRCm39) |
H1740Q |
probably benign |
Het |
| Icam5 |
A |
G |
9: 20,948,217 (GRCm39) |
H675R |
probably benign |
Het |
| Il18rap |
T |
C |
1: 40,564,049 (GRCm39) |
F56L |
probably benign |
Het |
| Iqgap3 |
T |
A |
3: 87,997,037 (GRCm39) |
|
probably null |
Het |
| Itsn1 |
T |
C |
16: 91,664,984 (GRCm39) |
|
probably benign |
Het |
| Jakmip3 |
A |
T |
7: 138,622,585 (GRCm39) |
D315V |
probably damaging |
Het |
| Kif24 |
A |
G |
4: 41,413,959 (GRCm39) |
Y328H |
probably damaging |
Het |
| Kmt2a |
A |
T |
9: 44,744,171 (GRCm39) |
|
probably benign |
Het |
| Kng1 |
A |
G |
16: 22,898,475 (GRCm39) |
E625G |
probably damaging |
Het |
| Man2b1 |
C |
T |
8: 85,823,675 (GRCm39) |
T973I |
probably benign |
Het |
| Masp2 |
G |
A |
4: 148,687,210 (GRCm39) |
V31M |
probably damaging |
Het |
| Myo18b |
C |
T |
5: 113,013,601 (GRCm39) |
R785H |
possibly damaging |
Het |
| Naa15 |
G |
A |
3: 51,350,212 (GRCm39) |
G103D |
probably damaging |
Het |
| Or4f15 |
A |
G |
2: 111,813,969 (GRCm39) |
V150A |
probably benign |
Het |
| Or5m11b |
A |
G |
2: 85,805,926 (GRCm39) |
Y113C |
probably damaging |
Het |
| Or7e177 |
T |
A |
9: 20,211,899 (GRCm39) |
D134E |
probably damaging |
Het |
| Papln |
A |
G |
12: 83,829,789 (GRCm39) |
N970S |
probably benign |
Het |
| Pick1 |
T |
A |
15: 79,135,928 (GRCm39) |
|
probably null |
Het |
| Pigr |
A |
C |
1: 130,769,498 (GRCm39) |
D103A |
probably benign |
Het |
| Plekhf1 |
A |
C |
7: 37,921,029 (GRCm39) |
F180V |
possibly damaging |
Het |
| Plxnc1 |
A |
G |
10: 94,669,504 (GRCm39) |
|
probably null |
Het |
| Polr3f |
A |
G |
2: 144,376,308 (GRCm39) |
I136V |
probably damaging |
Het |
| Ppp2r2c |
T |
C |
5: 37,097,468 (GRCm39) |
M218T |
possibly damaging |
Het |
| Prox2 |
C |
T |
12: 85,136,420 (GRCm39) |
V466I |
probably damaging |
Het |
| Prrc2a |
G |
A |
17: 35,373,909 (GRCm39) |
L1479F |
probably damaging |
Het |
| Rbm24 |
T |
A |
13: 46,575,313 (GRCm39) |
|
probably null |
Het |
| Rcc1l |
A |
T |
5: 134,195,560 (GRCm39) |
|
probably null |
Het |
| Ripk4 |
A |
C |
16: 97,556,323 (GRCm39) |
L140R |
probably damaging |
Het |
| Rmnd1 |
A |
T |
10: 4,372,135 (GRCm39) |
L188Q |
probably damaging |
Het |
| Rnf170 |
C |
T |
8: 26,630,992 (GRCm39) |
P249S |
probably damaging |
Het |
| Rras |
A |
G |
7: 44,667,595 (GRCm39) |
|
probably null |
Het |
| Rsf1 |
G |
A |
7: 97,229,117 (GRCm39) |
|
probably benign |
Het |
| Scn7a |
T |
A |
2: 66,530,458 (GRCm39) |
D629V |
probably damaging |
Het |
| Sipa1l3 |
A |
G |
7: 29,087,558 (GRCm39) |
S556P |
probably damaging |
Het |
| Smarca2 |
C |
T |
19: 26,608,292 (GRCm39) |
A117V |
probably damaging |
Het |
| Snca |
C |
T |
6: 60,792,702 (GRCm39) |
A69T |
probably damaging |
Het |
| Snx2 |
T |
C |
18: 53,342,737 (GRCm39) |
|
probably null |
Het |
| Spp1 |
T |
A |
5: 104,587,242 (GRCm39) |
S109T |
possibly damaging |
Het |
| Stoml3 |
T |
C |
3: 53,414,937 (GRCm39) |
L243P |
probably damaging |
Het |
| Susd2 |
A |
G |
10: 75,473,408 (GRCm39) |
F789L |
possibly damaging |
Het |
| Sycp1 |
A |
G |
3: 102,816,277 (GRCm39) |
M419T |
probably damaging |
Het |
| Thoc1 |
T |
C |
18: 9,993,330 (GRCm39) |
V563A |
probably benign |
Het |
| Tmprss11g |
T |
C |
5: 86,635,281 (GRCm39) |
I398V |
probably damaging |
Het |
| Tox3 |
A |
G |
8: 90,975,566 (GRCm39) |
L355P |
probably damaging |
Het |
| Tpp1 |
A |
G |
7: 105,396,223 (GRCm39) |
I492T |
probably benign |
Het |
| Trim21 |
A |
T |
7: 102,213,289 (GRCm39) |
L3Q |
probably damaging |
Het |
| Ttn |
A |
C |
2: 76,738,080 (GRCm39) |
V4153G |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,744,638 (GRCm39) |
|
probably benign |
Het |
| Unc80 |
A |
G |
1: 66,560,756 (GRCm39) |
E828G |
possibly damaging |
Het |
| Vav3 |
A |
G |
3: 109,416,170 (GRCm39) |
N263S |
possibly damaging |
Het |
| Vmn1r183 |
A |
C |
7: 23,754,982 (GRCm39) |
T262P |
possibly damaging |
Het |
| Vmn2r67 |
G |
A |
7: 84,799,142 (GRCm39) |
P522S |
possibly damaging |
Het |
| Vps35 |
T |
A |
8: 86,026,086 (GRCm39) |
M1L |
probably benign |
Het |
| Xpo7 |
A |
T |
14: 70,942,130 (GRCm39) |
L79* |
probably null |
Het |
| Zc3h14 |
G |
A |
12: 98,726,087 (GRCm39) |
R324H |
probably damaging |
Het |
| Zfp330 |
T |
C |
8: 83,499,613 (GRCm39) |
T6A |
probably damaging |
Het |
| Zfp948 |
T |
A |
17: 21,807,286 (GRCm39) |
H159Q |
unknown |
Het |
|
| Other mutations in Hecw1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00591:Hecw1
|
APN |
13 |
14,440,565 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL00813:Hecw1
|
APN |
13 |
14,452,961 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL00843:Hecw1
|
APN |
13 |
14,422,158 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00942:Hecw1
|
APN |
13 |
14,515,325 (GRCm39) |
splice site |
probably benign |
|
|
IGL00976:Hecw1
|
APN |
13 |
14,493,557 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01289:Hecw1
|
APN |
13 |
14,438,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01675:Hecw1
|
APN |
13 |
14,409,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01783:Hecw1
|
APN |
13 |
14,452,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01941:Hecw1
|
APN |
13 |
14,490,895 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02170:Hecw1
|
APN |
13 |
14,438,743 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL02172:Hecw1
|
APN |
13 |
14,438,734 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02214:Hecw1
|
APN |
13 |
14,474,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02350:Hecw1
|
APN |
13 |
14,422,923 (GRCm39) |
splice site |
probably null |
|
|
IGL02357:Hecw1
|
APN |
13 |
14,422,923 (GRCm39) |
splice site |
probably null |
|
|
IGL02372:Hecw1
|
APN |
13 |
14,438,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02591:Hecw1
|
APN |
13 |
14,531,821 (GRCm39) |
splice site |
probably benign |
|
|
IGL02718:Hecw1
|
APN |
13 |
14,481,520 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL02795:Hecw1
|
APN |
13 |
14,497,102 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02941:Hecw1
|
APN |
13 |
14,552,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03256:Hecw1
|
APN |
13 |
14,455,070 (GRCm39) |
missense |
probably benign |
0.36 |
|
IGL03256:Hecw1
|
APN |
13 |
14,455,069 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03366:Hecw1
|
APN |
13 |
14,552,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
deflated
|
UTSW |
13 |
14,422,205 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
Demoralized
|
UTSW |
13 |
14,491,403 (GRCm39) |
nonsense |
probably null |
|
|
Letdown
|
UTSW |
13 |
14,491,077 (GRCm39) |
missense |
probably benign |
0.40 |
|
BB001:Hecw1
|
UTSW |
13 |
14,497,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB011:Hecw1
|
UTSW |
13 |
14,497,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03014:Hecw1
|
UTSW |
13 |
14,420,393 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4378001:Hecw1
|
UTSW |
13 |
14,552,368 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0555:Hecw1
|
UTSW |
13 |
14,411,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0617:Hecw1
|
UTSW |
13 |
14,455,027 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1476:Hecw1
|
UTSW |
13 |
14,480,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1479:Hecw1
|
UTSW |
13 |
14,491,077 (GRCm39) |
missense |
probably benign |
0.40 |
|
R1551:Hecw1
|
UTSW |
13 |
14,491,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Hecw1
|
UTSW |
13 |
14,552,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1584:Hecw1
|
UTSW |
13 |
14,515,328 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1735:Hecw1
|
UTSW |
13 |
14,552,350 (GRCm39) |
missense |
probably null |
0.09 |
|
R1872:Hecw1
|
UTSW |
13 |
14,455,034 (GRCm39) |
nonsense |
probably null |
|
|
R1897:Hecw1
|
UTSW |
13 |
14,552,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2054:Hecw1
|
UTSW |
13 |
14,471,998 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2085:Hecw1
|
UTSW |
13 |
14,438,672 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2134:Hecw1
|
UTSW |
13 |
14,552,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2172:Hecw1
|
UTSW |
13 |
14,552,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2258:Hecw1
|
UTSW |
13 |
14,490,723 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2274:Hecw1
|
UTSW |
13 |
14,520,653 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2275:Hecw1
|
UTSW |
13 |
14,520,653 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2937:Hecw1
|
UTSW |
13 |
14,420,421 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R3830:Hecw1
|
UTSW |
13 |
14,520,643 (GRCm39) |
missense |
probably benign |
0.13 |
|
R3971:Hecw1
|
UTSW |
13 |
14,411,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4065:Hecw1
|
UTSW |
13 |
14,491,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4066:Hecw1
|
UTSW |
13 |
14,491,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4235:Hecw1
|
UTSW |
13 |
14,491,724 (GRCm39) |
missense |
probably benign |
0.42 |
|
R4366:Hecw1
|
UTSW |
13 |
14,490,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4382:Hecw1
|
UTSW |
13 |
14,490,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4385:Hecw1
|
UTSW |
13 |
14,490,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4510:Hecw1
|
UTSW |
13 |
14,531,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4511:Hecw1
|
UTSW |
13 |
14,531,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4558:Hecw1
|
UTSW |
13 |
14,422,190 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4804:Hecw1
|
UTSW |
13 |
14,480,570 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4854:Hecw1
|
UTSW |
13 |
14,491,477 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5104:Hecw1
|
UTSW |
13 |
14,515,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5113:Hecw1
|
UTSW |
13 |
14,520,614 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5167:Hecw1
|
UTSW |
13 |
14,460,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5392:Hecw1
|
UTSW |
13 |
14,420,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5394:Hecw1
|
UTSW |
13 |
14,497,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5504:Hecw1
|
UTSW |
13 |
14,515,487 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5764:Hecw1
|
UTSW |
13 |
14,497,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6038:Hecw1
|
UTSW |
13 |
14,520,647 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6038:Hecw1
|
UTSW |
13 |
14,520,647 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6228:Hecw1
|
UTSW |
13 |
14,520,623 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Hecw1
|
UTSW |
13 |
14,409,010 (GRCm39) |
nonsense |
probably null |
|
|
R6252:Hecw1
|
UTSW |
13 |
14,446,664 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6321:Hecw1
|
UTSW |
13 |
14,697,414 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6325:Hecw1
|
UTSW |
13 |
14,491,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6328:Hecw1
|
UTSW |
13 |
14,422,205 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6557:Hecw1
|
UTSW |
13 |
14,491,231 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6566:Hecw1
|
UTSW |
13 |
14,471,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6597:Hecw1
|
UTSW |
13 |
14,491,403 (GRCm39) |
nonsense |
probably null |
|
|
R6821:Hecw1
|
UTSW |
13 |
14,438,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6914:Hecw1
|
UTSW |
13 |
14,491,423 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7078:Hecw1
|
UTSW |
13 |
14,609,044 (GRCm39) |
start codon destroyed |
probably null |
0.21 |
|
R7114:Hecw1
|
UTSW |
13 |
14,486,356 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7140:Hecw1
|
UTSW |
13 |
14,491,118 (GRCm39) |
missense |
probably benign |
|
|
R7150:Hecw1
|
UTSW |
13 |
14,609,045 (GRCm39) |
start codon destroyed |
probably benign |
|
|
R7288:Hecw1
|
UTSW |
13 |
14,490,821 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7447:Hecw1
|
UTSW |
13 |
14,531,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7479:Hecw1
|
UTSW |
13 |
14,515,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7552:Hecw1
|
UTSW |
13 |
14,490,835 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7590:Hecw1
|
UTSW |
13 |
14,438,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7787:Hecw1
|
UTSW |
13 |
14,493,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7803:Hecw1
|
UTSW |
13 |
14,408,927 (GRCm39) |
missense |
probably benign |
0.25 |
|
R7924:Hecw1
|
UTSW |
13 |
14,497,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7967:Hecw1
|
UTSW |
13 |
14,552,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Hecw1
|
UTSW |
13 |
14,422,286 (GRCm39) |
splice site |
probably null |
|
|
R8195:Hecw1
|
UTSW |
13 |
14,480,692 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8252:Hecw1
|
UTSW |
13 |
14,515,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8696:Hecw1
|
UTSW |
13 |
14,531,743 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8827:Hecw1
|
UTSW |
13 |
14,438,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8867:Hecw1
|
UTSW |
13 |
14,422,275 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8914:Hecw1
|
UTSW |
13 |
14,422,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8942:Hecw1
|
UTSW |
13 |
14,481,395 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9126:Hecw1
|
UTSW |
13 |
14,546,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9185:Hecw1
|
UTSW |
13 |
14,491,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9203:Hecw1
|
UTSW |
13 |
14,491,243 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9236:Hecw1
|
UTSW |
13 |
14,490,643 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9291:Hecw1
|
UTSW |
13 |
14,491,522 (GRCm39) |
missense |
probably benign |
|
|
R9312:Hecw1
|
UTSW |
13 |
14,546,567 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9438:Hecw1
|
UTSW |
13 |
14,481,414 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9502:Hecw1
|
UTSW |
13 |
14,546,567 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9642:Hecw1
|
UTSW |
13 |
14,515,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF001:Hecw1
|
UTSW |
13 |
14,472,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0020:Hecw1
|
UTSW |
13 |
14,405,308 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
X0066:Hecw1
|
UTSW |
13 |
14,455,045 (GRCm39) |
missense |
probably benign |
0.13 |
|
Z1176:Hecw1
|
UTSW |
13 |
14,474,918 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
| Predicted Primers |
|
| Posted On |
2018-03-15 |
Incidental Mutation