Mutagenetix > Incidental Mutation

Incidental Mutation 'FR4304:Zfp462'

510977

Institutional Source

Beutler Lab

Gene Symbol

Zfp462

Ensembl Gene

ENSMUSG00000060206

Gene Name

zinc finger protein 462

Synonyms

Zfpip, 9430078C22Rik, Gt4-2

Accession Numbers

Essential gene?

Probably essential (E-score: 0.776) question?

Stock #

FR4304 ()

Quality Score

217.576

Status

Not validated

Chromosome

Chromosomal Location

54945048-55083563 bp(+) (GRCm38)

Type of Mutation

unclassified

DNA Base Change (assembly)

GCCACC to GCCACCTCAGCCACAACCACC at 55009757 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000122775 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000030131] [ENSMUST00000079605] [ENSMUST00000098070] [ENSMUST00000133895]

AlphaFold

B1AWL2

Predicted Effect

probably benign
Transcript: ENSMUST00000030131

SMART Domains

Protein: ENSMUSP00000030131
Gene: ENSMUSG00000060206

Domain	Start	End	E-Value	Type
ZnF_C2H2	35	58	4.81e0	SMART
ZnF_C2H2	106	129	6.67e-2	SMART
ZnF_C2H2	153	176	3.47e0	SMART
ZnF_C2H2	210	233	7.29e0	SMART
ZnF_C2H2	311	334	2.17e-1	SMART
ZnF_C2H2	356	379	6.57e0	SMART
ZnF_C2H2	418	441	5.34e-1	SMART
low complexity region	450	463	N/A	INTRINSIC
ZnF_C2H2	501	524	8.22e-2	SMART
ZnF_C2H2	538	561	5.34e0	SMART
ZnF_C2H2	608	631	6.4e0	SMART
low complexity region	655	676	N/A	INTRINSIC
ZnF_C2H2	687	711	3.05e1	SMART
ZnF_C2H2	733	755	1.08e-1	SMART
low complexity region	757	771	N/A	INTRINSIC
ZnF_C2H2	809	831	1.51e0	SMART
ZnF_C2H2	892	914	3.11e-2	SMART
ZnF_C2H2	926	948	4.11e-2	SMART
ZnF_C2H2	955	978	4.98e-1	SMART
ZnF_C2H2	984	1007	5.5e-3	SMART
ZnF_C2H2	1092	1115	7.05e-1	SMART
ZnF_C2H2	1121	1144	5.48e0	SMART
ZnF_C2H2	1155	1177	6.13e-1	SMART
ZnF_C2H2	1201	1223	1.26e-2	SMART
ZnF_C2H2	1229	1252	2.02e-1	SMART
low complexity region	1273	1296	N/A	INTRINSIC
ZnF_C2H2	1315	1337	2.2e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000079605

SMART Domains

Protein: ENSMUSP00000078555
Gene: ENSMUSG00000060206

Domain	Start	End	E-Value	Type
ZnF_C2H2	35	58	4.81e0	SMART
ZnF_C2H2	106	129	6.67e-2	SMART
ZnF_C2H2	153	176	3.47e0	SMART
ZnF_C2H2	210	233	7.29e0	SMART
ZnF_C2H2	311	334	2.17e-1	SMART
ZnF_C2H2	356	379	6.57e0	SMART
ZnF_C2H2	418	441	5.34e-1	SMART
low complexity region	450	463	N/A	INTRINSIC
ZnF_C2H2	501	524	8.22e-2	SMART
ZnF_C2H2	538	561	5.34e0	SMART
ZnF_C2H2	608	631	6.4e0	SMART
low complexity region	655	676	N/A	INTRINSIC
ZnF_C2H2	687	711	3.05e1	SMART
ZnF_C2H2	733	755	1.08e-1	SMART
low complexity region	757	771	N/A	INTRINSIC
ZnF_C2H2	809	831	1.51e0	SMART
ZnF_C2H2	893	915	3.11e-2	SMART
ZnF_C2H2	927	949	4.11e-2	SMART
ZnF_C2H2	956	979	4.98e-1	SMART
ZnF_C2H2	985	1008	5.5e-3	SMART
ZnF_C2H2	1093	1116	7.05e-1	SMART
ZnF_C2H2	1122	1145	5.48e0	SMART
ZnF_C2H2	1156	1178	6.13e-1	SMART
ZnF_C2H2	1202	1224	1.26e-2	SMART
ZnF_C2H2	1230	1253	2.02e-1	SMART
low complexity region	1274	1297	N/A	INTRINSIC
ZnF_C2H2	1316	1338	2.2e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000098070

SMART Domains

Protein: ENSMUSP00000095677
Gene: ENSMUSG00000060206

Domain	Start	End	E-Value	Type
ZnF_C2H2	4	27	5.81e-2	SMART
low complexity region	81	94	N/A	INTRINSIC
ZnF_C2H2	108	131	1.79e-2	SMART
ZnF_C2H2	162	185	4.65e-1	SMART
low complexity region	194	215	N/A	INTRINSIC
ZnF_C2H2	243	266	4.98e-1	SMART
low complexity region	332	343	N/A	INTRINSIC
ZnF_C2H2	440	463	1.01e-1	SMART
ZnF_C2H2	471	493	2.86e-1	SMART
low complexity region	503	515	N/A	INTRINSIC
low complexity region	536	592	N/A	INTRINSIC
ZnF_C2H2	593	616	2.53e-2	SMART
low complexity region	707	736	N/A	INTRINSIC
ZnF_C2H2	835	858	5.62e0	SMART
ZnF_C2H2	878	900	2.14e0	SMART
ZnF_C2H2	917	940	6.67e-2	SMART
ZnF_C2H2	1023	1046	5.72e-1	SMART
low complexity region	1092	1100	N/A	INTRINSIC
ZnF_C2H2	1107	1130	4.23e0	SMART
ZnF_C2H2	1183	1206	4.81e0	SMART
ZnF_C2H2	1254	1277	6.67e-2	SMART
ZnF_C2H2	1301	1324	3.47e0	SMART
ZnF_C2H2	1358	1381	7.29e0	SMART
ZnF_C2H2	1459	1482	2.17e-1	SMART
ZnF_C2H2	1504	1527	6.57e0	SMART
ZnF_C2H2	1566	1589	5.34e-1	SMART
low complexity region	1598	1611	N/A	INTRINSIC
ZnF_C2H2	1649	1672	8.22e-2	SMART
ZnF_C2H2	1686	1709	5.34e0	SMART
ZnF_C2H2	1756	1779	6.4e0	SMART
low complexity region	1803	1824	N/A	INTRINSIC
ZnF_C2H2	1835	1859	3.05e1	SMART
ZnF_C2H2	1881	1903	1.08e-1	SMART
low complexity region	1905	1919	N/A	INTRINSIC
ZnF_C2H2	1957	1979	1.51e0	SMART
ZnF_C2H2	2014	2036	4.11e-2	SMART
ZnF_C2H2	2043	2066	4.98e-1	SMART
ZnF_C2H2	2072	2095	5.5e-3	SMART
ZnF_C2H2	2180	2203	7.05e-1	SMART
ZnF_C2H2	2209	2232	5.48e0	SMART
ZnF_C2H2	2243	2265	6.13e-1	SMART
ZnF_C2H2	2289	2311	1.26e-2	SMART
ZnF_C2H2	2317	2340	2.02e-1	SMART
low complexity region	2361	2384	N/A	INTRINSIC
ZnF_C2H2	2403	2425	2.2e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000133895

SMART Domains

Protein: ENSMUSP00000122775
Gene: ENSMUSG00000060206

Domain	Start	End	E-Value	Type
ZnF_C2H2	4	27	5.81e-2	SMART
low complexity region	81	93	N/A	INTRINSIC

Coding Region Coverage

1x: 99.8%
3x: 99.6%
10x: 98.6%
20x: 96.4%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to C2H2-type zinc finger family of proteins. It contains multiple C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]

Allele List at MGI

Other mutations in this stock

Total: 136 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700001K19Rik	CTT	CTTTTT	12: 110,668,449		probably benign	Homo
1700001K19Rik	TTC	TTCGTC	12: 110,668,450		probably benign	Homo
4930402H24Rik	TCC	TCCCCC	2: 130,770,748		probably benign	Het
4930433I11Rik	ACCTC	AC	7: 40,993,056		probably benign	Het
4930447C04Rik	AAGT	A	12: 72,881,287		probably benign	Homo
4930548H24Rik	GAGAAG	GAG	5: 31,487,373		probably benign	Homo
Acbd4	CAG	CAGACTAG	11: 103,104,105		probably null	Homo
Ahdc1	CT	CTCTT	4: 133,062,759		probably benign	Homo
Alpk3	TCT	TCTGCT	7: 81,077,762		probably benign	Het
Anapc4	C	T	5: 52,864,526	T650M	probably damaging	Homo
Ankhd1	GGCGGC	GGCGGCTGCGGC	18: 36,560,924		probably benign	Het
Ankrd35	TAGC	TAGCAGC	3: 96,683,847		probably benign	Homo
Apc	GCCAATAAA	GCCAATAAAACCAATAAA	18: 34,281,997		probably benign	Het
Apol6	TTGT	TTGTCTGT	15: 77,051,436		probably null	Het
Arhgap30	TGGCCC	TGGCCCTGGCCCAGGCCTTGGCCCCGGCCC	1: 171,405,168		probably benign	Het
Arpc1b	GCC	GCCTGTCC	5: 145,126,791		probably null	Het
BC051142	A	AGCC	17: 34,460,055		probably benign	Het
BC051142	GC	GCATC	17: 34,460,077		probably benign	Het
Blm	CT	CTACGT	7: 80,463,773		probably null	Homo
Blm	TCCTCCTCCTCC	TCCTCCTCCTCCACCTCCTCCTCC	7: 80,512,919		probably benign	Het
Btnl10	GA	GAATA	11: 58,923,930		probably benign	Homo
Cacna1f	AGG	AGGCGG	X: 7,620,061		probably benign	Het
Calhm3	CG	CGG	19: 47,151,896		probably null	Homo
Catsper2	C	CTTTTACTTTTTA	2: 121,397,542		probably null	Homo
Catsper2	CAT	CATTAT	2: 121,397,782		probably benign	Het
Ccdc15	AC	ACTTTCC	9: 37,315,157		probably null	Het
Ccdc162	T	C	10: 41,556,121	D1792G	possibly damaging	Het
Ccdc170	CCA	CCATCA	10: 4,561,021		probably benign	Het
Ccdc73	TAAG	T	2: 104,991,840		probably benign	Homo
Ccdc85c	GCC	GCCCCC	12: 108,274,612		probably benign	Het
Cd22	C	T	7: 30,878,082	R2H	possibly damaging	Het
Cd80	AGA	AGAGGA	16: 38,486,315		probably benign	Homo
Cep89	GACT	G	7: 35,409,641		probably benign	Het
Cfap74	A	G	4: 155,415,760	D21G	possibly damaging	Homo
Cgref1	T	TCTA	5: 30,933,780		probably benign	Homo
Chd4	GCC	GCCACTCCC	6: 125,122,144		probably benign	Het
Cnpy3	TCC	TCCCCC	17: 46,736,743		probably benign	Het
Cnpy3	TCC	TCCACC	17: 46,736,746		probably benign	Het
Cntnap1	AGCCCC	AGCCCCCGCCCC	11: 101,189,581		probably benign	Het
Cntnap1	CCCCAG	CCCCAGACCCAG	11: 101,189,589		probably benign	Het
Col2a1	C	A	15: 97,988,981		probably null	Homo
Cpeb4	T	TGA	11: 31,927,638		probably benign	Homo
Cpne1	AGA	AGAGAGA	2: 156,072,025		probably null	Homo
Cttnbp2	ATTGCTG	ATTGCTGTTGCTG	6: 18,367,458		probably benign	Het
Dhx37	CTGG	C	5: 125,427,530		probably benign	Het
Dhx8	CGAGAC	CGAGACGGAGAC	11: 101,738,188		probably benign	Homo
Dnah12	G	T	14: 26,849,385	G2817V	probably damaging	Homo
Dst	C	A	1: 34,200,964	S1798Y	probably damaging	Het
Eif3a	TA	TATTTCA	19: 60,775,290		probably benign	Homo
Ermn	TTC	TTCCTC	2: 58,048,078		probably benign	Het
Ermn	CTT	CTTGTT	2: 58,048,086		probably benign	Het
Fbxo43	GCCTGT	GCCTGTTCCTGT	15: 36,152,094		probably benign	Het
Fbxo43	TGTGCC	TGTGCCAGTGCC	15: 36,152,097		probably benign	Het
Fbxo43	GCCTGT	GCCTGTCCCTGT	15: 36,152,100		probably benign	Het
Fmn1	TCCTCC	TCCTCCCCCTCC	2: 113,525,774		probably benign	Het
Fmn1	TCC	TCCTCCACC	2: 113,525,783		probably benign	Homo
Foxd3	GGACCCTACGGCCG	GG	4: 99,657,396		probably benign	Homo
Frmpd2	G	T	14: 33,511,021	L399F	probably damaging	Homo
Gabre	ACTCCGGCTCCGGCTCAGGCTCAGGCTCCGGCTCAGGCTCCGGCTCCGGCTCCGGCTC	ACTCCGGCTCCGGCTCCGGCTCAGGCTCAGGCTCCGGCTCAGGCTCCGGCTCCGGCTCCGGCTC	X: 72,270,042		probably benign	Homo
Gbp2b	A	G	3: 142,603,652	I175V	probably benign	Het
Gm4340	CAG	CAGAAG	10: 104,196,072		probably benign	Het
Gm4340	AGC	AGCGGC	10: 104,196,082		probably benign	Het
Gm5114	T	C	7: 39,411,105	R107G	probably benign	Het
Gm5114	A	C	7: 39,411,106	H106Q	probably benign	Het
Gm9573	T	G	17: 35,622,121		probably benign	Homo
H2-Q4	G	A	17: 35,380,405	D155N	probably damaging	Het
H2-T10	TGTTTCCCACTG	T	17: 36,120,281		probably null	Het
Hist1h1t	GAGAA	GA	13: 23,695,920		probably benign	Homo
Ifi203	C	T	1: 173,928,328		probably benign	Het
Ifi208	ATGGTG	ATG	1: 173,677,698		probably benign	Homo
Ighv5-9	C	T	12: 113,661,877	S82N	probably benign	Homo
Il17rd	CGG	CGGTGG	14: 27,082,680		probably benign	Het
Il2	AGTGG	AGTGGGGCTTGAGGTGG	3: 37,125,826		probably benign	Het
Ipo9	TCC	TCCGCC	1: 135,386,275		probably benign	Het
Ipo9	CCT	CCTACT	1: 135,386,279		probably null	Het
Isg20l2	AAG	AAGCAG	3: 87,931,712		probably benign	Homo
Kmt2b	TCCTCC	TCCTCCCCCTCC	7: 30,586,363		probably benign	Het
Kmt2c	TGCTGCTG	TGCTGCTGCTGCTG	5: 25,315,766		probably benign	Homo
Krt10	CGCC	CGCCGCC	11: 99,386,199		probably benign	Het
Krt10	CCTCCT	CCTCCTACTCCT	11: 99,389,274		probably benign	Het
Las1l	GAG	GAGCAG	X: 95,940,820		probably benign	Het
Las1l	AGG	AGGCGG	X: 95,940,821		probably benign	Het
Lkaaear1	GCTCCAGCTCCAGCTCCAGCTCCA	GCTCCAGCTCCATCTCCAGCTCCAGCTCCAGCTCCA	2: 181,697,579		probably benign	Het
Lrch1	A	T	14: 74,819,565	C241S	possibly damaging	Het
Lrit3	G	GCTT	3: 129,788,819		probably benign	Het
Maml2	GCAGCAGCAACAGCAGCA	GCAGCAGCA	9: 13,621,459		probably benign	Homo
Mast4	T	TTTC	13: 102,734,862		probably benign	Het
Med12l	AGC	AGCGGC	3: 59,275,982		probably benign	Het
Noc2l	TGC	TGCAGC	4: 156,240,096		probably benign	Het
Nrg3	G	GACATTT	14: 38,397,273		probably benign	Homo
Olfr635	TCC	TCCC	7: 103,979,903		probably null	Het
Padi3	TCTCAC	TC	4: 140,792,972		probably benign	Homo
Park2	G	A	17: 11,854,763	V323M	probably damaging	Het
Patl2	GCT	GCTTCT	2: 122,126,135		probably benign	Het
Pdik1l	TTTT	TTTTGTTTTTGGTTT	4: 134,279,374		probably null	Homo
Pik3c2g	AG	AGAGGG	6: 139,635,656		probably null	Homo
Plekhs1	T	TTCAGACCTCCCC	19: 56,479,858		probably benign	Het
Prkd3	G	T	17: 78,975,820		probably null	Homo
Prr13	TCC	TCCCCC	15: 102,462,177		probably benign	Homo
Prrc2b	G	A	2: 32,221,167	A1852T	probably damaging	Homo
Ptms	CTT	CTTTTT	6: 124,914,458		probably benign	Homo
Rtl1	TTCCTCTTCCTCCTC	TTCCTC	12: 109,591,198		probably benign	Homo
Scaf4	TGCGGC	TGC	16: 90,229,854		probably benign	Homo
Serac1	T	A	17: 6,070,808	K70N	probably damaging	Homo
Six3	CGG	CGGTGG	17: 85,621,368		probably benign	Het
Sry	GTG	GTGCTG	Y: 2,662,837		probably benign	Homo
Stard8	GGAAGA	GGAAGAAGA	X: 99,066,505		probably benign	Het
Supt20	TTCAGCA	TTCAGCATCAGCA	3: 54,727,647		probably benign	Het
Supt20	AGCAGC	AGCAGCGGCAGC	3: 54,727,662		probably benign	Het
Supt20	CAGCAG	CAGCAGTAGCAG	3: 54,727,664		probably null	Het
Sytl1	CTCT	C	4: 133,256,993		probably benign	Homo
Tcof1	AGC	AGCGGC	18: 60,835,742		probably benign	Het
Tdpoz2	T	TCA	3: 93,651,615		probably null	Homo
Tert	GCC	GCCAAGGGTTCC	13: 73,648,302		probably benign	Homo
Tfeb	GCA	GCAACA	17: 47,786,094		probably benign	Het
Ticrr	ATT	ATTTTT	7: 79,694,311		probably benign	Homo
Tnfaip8	ACACACACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC	AC	18: 50,046,839		probably null	Homo
Tnfrsf9	T	TGCC	4: 150,934,395		probably benign	Homo
Tob1	GCA	GCAACA	11: 94,214,464		probably benign	Het
Tob1	CA	CAGTA	11: 94,214,477		probably null	Het
Trav15-2-dv6-2	GGGAG	GGGAGGAG	14: 53,649,750		probably benign	Homo
Triobp	TCGTCG	TCGTCGTCG	15: 78,993,387		probably benign	Homo
Tsen2	AGG	AGGGGG	6: 115,560,069		probably benign	Het
Ubtf	TCC	TCCGCC	11: 102,306,956		probably benign	Het
Ubtf	CTCGTCGTC	CTCGTCGTCGTC	11: 102,306,958		probably benign	Het
Vars	TGG	TGGAGTCCTGGGCGG	17: 35,015,989		probably benign	Homo
Vmn1r171	C	T	7: 23,632,680	A110V	probably benign	Het
Vmn2r31	G	T	7: 7,384,608	Q655K	probably damaging	Het
Vmn2r87	C	T	10: 130,478,714	M334I	probably benign	Homo
Zc3h13	AGATGTGCG	AGATGTGCGGGATGTGCG	14: 75,323,603		probably benign	Het
Zc3h13	CG	CGAGATGTGTG	14: 75,323,610		probably benign	Het
Zfp282	GGC	GGCCGC	6: 47,904,797		probably benign	Het
Zfp384	AGGC	AGGCCCAGGCCCCGGC	6: 125,036,493		probably benign	Het
Zfp459	TGA	TGAGCGA	13: 67,408,274		probably null	Homo
Zfp598	CACCAC	CACCACAACCAC	17: 24,680,775		probably benign	Het
Zfp831	CCT	CCTGCT	2: 174,645,481		probably benign	Het

Other mutations in Zfp462

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00162:Zfp462	APN	4	55011483	splice site	probably null
IGL00421:Zfp462	APN	4	55023576	missense	probably benign	0.00
IGL00899:Zfp462	APN	4	55007732	missense	probably damaging	1.00
IGL01549:Zfp462	APN	4	55013181	missense	probably damaging	1.00
IGL01627:Zfp462	APN	4	55008912	missense	possibly damaging	0.93
IGL01715:Zfp462	APN	4	55008586	missense	probably benign	0.20
IGL01862:Zfp462	APN	4	55023441	missense	probably damaging	1.00
IGL01878:Zfp462	APN	4	55010613	missense	probably damaging	1.00
IGL01913:Zfp462	APN	4	55012138	missense	probably benign	0.04
IGL02029:Zfp462	APN	4	55079395	splice site	probably benign
IGL02338:Zfp462	APN	4	55010292	missense	possibly damaging	0.88
IGL02552:Zfp462	APN	4	55010613	missense	probably damaging	1.00
IGL02623:Zfp462	APN	4	55012986	missense	probably damaging	1.00
IGL02750:Zfp462	APN	4	55060236	missense	probably null	1.00
IGL02815:Zfp462	APN	4	55051303	missense	probably damaging	1.00
IGL03204:Zfp462	APN	4	55080785	missense	possibly damaging	0.80
FR4304:Zfp462	UTSW	4	55009758	unclassified	probably benign
FR4737:Zfp462	UTSW	4	55009758	unclassified	probably benign
FR4737:Zfp462	UTSW	4	55009760	unclassified	probably benign
FR4976:Zfp462	UTSW	4	55009760	unclassified	probably benign
FR4976:Zfp462	UTSW	4	55009761	unclassified	probably benign
P0035:Zfp462	UTSW	4	55009086	missense	probably benign
R0052:Zfp462	UTSW	4	55011762	missense	probably benign	0.03
R0143:Zfp462	UTSW	4	55023402	splice site	probably benign
R0145:Zfp462	UTSW	4	55010529	missense	probably damaging	1.00
R0315:Zfp462	UTSW	4	55079314	missense	probably damaging	0.99
R0349:Zfp462	UTSW	4	55008768	missense	probably benign
R0359:Zfp462	UTSW	4	55013689	missense	probably damaging	1.00
R0413:Zfp462	UTSW	4	55010534	missense	probably damaging	0.99
R0554:Zfp462	UTSW	4	55013689	missense	probably damaging	1.00
R0616:Zfp462	UTSW	4	55011951	missense	probably damaging	1.00
R0631:Zfp462	UTSW	4	55007563	start codon destroyed	possibly damaging	0.60
R1086:Zfp462	UTSW	4	55013000	missense	probably damaging	1.00
R1499:Zfp462	UTSW	4	55060046	missense	probably damaging	1.00
R1509:Zfp462	UTSW	4	55007667	missense	probably damaging	1.00
R1526:Zfp462	UTSW	4	55009002	missense	probably benign
R1541:Zfp462	UTSW	4	55008928	missense	possibly damaging	0.53
R1691:Zfp462	UTSW	4	55013489	missense	possibly damaging	0.70
R1843:Zfp462	UTSW	4	55010010	missense	possibly damaging	0.88
R2086:Zfp462	UTSW	4	55010830	missense	probably damaging	1.00
R2109:Zfp462	UTSW	4	55008496	missense	probably benign	0.00
R2148:Zfp462	UTSW	4	55013670	missense	probably benign	0.01
R2179:Zfp462	UTSW	4	55009524	missense	possibly damaging	0.73
R2325:Zfp462	UTSW	4	55013712	missense	probably benign
R2352:Zfp462	UTSW	4	55008313	missense	probably null
R2566:Zfp462	UTSW	4	55008522	missense	probably benign	0.00
R3879:Zfp462	UTSW	4	55060095	missense	probably damaging	1.00
R3969:Zfp462	UTSW	4	55012402	missense	probably damaging	1.00
R4273:Zfp462	UTSW	4	55008411	missense	probably benign	0.00
R4413:Zfp462	UTSW	4	55012672	missense	probably damaging	0.99
R4510:Zfp462	UTSW	4	55008934	missense	possibly damaging	0.86
R4511:Zfp462	UTSW	4	55008934	missense	possibly damaging	0.86
R4609:Zfp462	UTSW	4	55011889	missense	probably damaging	1.00
R4632:Zfp462	UTSW	4	55012981	missense	probably damaging	1.00
R4649:Zfp462	UTSW	4	55009349	missense	probably benign
R4682:Zfp462	UTSW	4	55011376	missense	probably damaging	1.00
R4696:Zfp462	UTSW	4	55008612	missense	probably benign
R4744:Zfp462	UTSW	4	55011598	missense	probably damaging	1.00
R4747:Zfp462	UTSW	4	55013476	missense	probably benign	0.00
R4819:Zfp462	UTSW	4	55060044	missense	probably damaging	1.00
R4827:Zfp462	UTSW	4	55012213	missense	probably damaging	1.00
R4854:Zfp462	UTSW	4	55010668	missense	probably damaging	1.00
R4879:Zfp462	UTSW	4	55009444	missense	probably benign	0.02
R4891:Zfp462	UTSW	4	55060055	missense	probably damaging	1.00
R4993:Zfp462	UTSW	4	55051204	missense	possibly damaging	0.62
R5118:Zfp462	UTSW	4	55010667	missense	probably damaging	1.00
R5171:Zfp462	UTSW	4	55016986	splice site	probably null
R5173:Zfp462	UTSW	4	55011115	missense	probably damaging	0.99
R5221:Zfp462	UTSW	4	55016887	missense	possibly damaging	0.86
R5268:Zfp462	UTSW	4	55012299	missense	probably benign
R5314:Zfp462	UTSW	4	55013178	missense	probably damaging	1.00
R5429:Zfp462	UTSW	4	55060077	missense	probably damaging	1.00
R5518:Zfp462	UTSW	4	55009818	missense	probably damaging	0.99
R5525:Zfp462	UTSW	4	55050281	missense	possibly damaging	0.73
R5620:Zfp462	UTSW	4	55013464	missense	probably benign	0.01
R5775:Zfp462	UTSW	4	55010590	missense	probably damaging	0.99
R6126:Zfp462	UTSW	4	55023573	missense	probably benign	0.01
R6280:Zfp462	UTSW	4	55010253	missense	probably benign	0.00
R6325:Zfp462	UTSW	4	55080680	missense	probably benign	0.04
R6542:Zfp462	UTSW	4	55023433	missense	probably damaging	1.00
R6612:Zfp462	UTSW	4	55012324	splice site	probably null
R6663:Zfp462	UTSW	4	55008933	missense	possibly damaging	0.53
R6872:Zfp462	UTSW	4	55012326	missense	probably benign	0.01
R6889:Zfp462	UTSW	4	55007671	missense	probably damaging	1.00
R6896:Zfp462	UTSW	4	55009544	missense	possibly damaging	0.72
R6913:Zfp462	UTSW	4	55007775	missense	probably benign	0.25
R6988:Zfp462	UTSW	4	55080716	missense	probably benign	0.00
R7131:Zfp462	UTSW	4	55009380	missense	probably benign
R7151:Zfp462	UTSW	4	55051271	missense	probably damaging	0.99
R7684:Zfp462	UTSW	4	55008908	missense	probably benign
R7741:Zfp462	UTSW	4	55008637	missense	probably benign	0.00
R7750:Zfp462	UTSW	4	55016958	missense	probably benign	0.06
R7812:Zfp462	UTSW	4	55008509	missense	probably benign	0.00
R7863:Zfp462	UTSW	4	55007747	missense	probably benign
R7898:Zfp462	UTSW	4	55012995	missense	probably damaging	0.98
R7993:Zfp462	UTSW	4	55011907	missense	probably damaging	1.00
R7995:Zfp462	UTSW	4	55011907	missense	probably damaging	1.00
R8023:Zfp462	UTSW	4	55073106	critical splice donor site	probably null
R8394:Zfp462	UTSW	4	55011862	missense	probably damaging	1.00
R8669:Zfp462	UTSW	4	55051313	missense	probably damaging	0.99
R8877:Zfp462	UTSW	4	55011097	missense	probably damaging	0.98
R8980:Zfp462	UTSW	4	55009681	unclassified	probably benign
R9023:Zfp462	UTSW	4	55007563	start codon destroyed	probably null	0.00
R9243:Zfp462	UTSW	4	55009595	nonsense	probably null
R9378:Zfp462	UTSW	4	55011510	missense	probably benign	0.00
R9417:Zfp462	UTSW	4	55016988	missense	probably benign	0.26
R9476:Zfp462	UTSW	4	55080735	missense	probably benign
R9510:Zfp462	UTSW	4	55080735	missense	probably benign
R9610:Zfp462	UTSW	4	55009545	missense	possibly damaging	0.73
R9628:Zfp462	UTSW	4	55009423	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- CTTACGAGAGCTCCAGCATC -3'
(R):5'- GAGGTCTGACTTTTCTTCACAGTG -3'

Sequencing Primer
(F):5'- TTACGAGAGCTCCAGCATCAATGG -3'
(R):5'- ATCCGTCTCATTTTCCAGTGGTAGG -3'

Posted On

2018-04-05