Mutagenetix > Incidental Mutation

Incidental Mutation 'FR4304:Ticrr'

511008

Institutional Source

Beutler Lab

Gene Symbol

Ticrr

Ensembl Gene

ENSMUSG00000046591

Gene Name

TOPBP1-interacting checkpoint and replication regulator

Synonyms

5730590G19Rik

Accession Numbers

Essential gene?

Probably essential (E-score: 0.947) question?

Stock #

FR4304 ()

Quality Score

129.457

Status

Not validated

Chromosome

Chromosomal Location

79660196-79698148 bp(+) (GRCm38)

Type of Mutation

intron

DNA Base Change (assembly)

ATT to ATTTTT at 79694311 bp (GRCm38)

Zygosity

Homozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000146155 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000035977] [ENSMUST00000059836] [ENSMUST00000178048] [ENSMUST00000183846] [ENSMUST00000184137] [ENSMUST00000206591] [ENSMUST00000206622]

AlphaFold

Q8BQ33

Predicted Effect

probably benign
Transcript: ENSMUST00000035977

SMART Domains

Protein: ENSMUSP00000041377
Gene: ENSMUSG00000046591

Domain	Start	End	E-Value	Type
low complexity region	23	31	N/A	INTRINSIC
Pfam:Treslin_N	211	1005	N/A	PFAM
low complexity region	1186	1197	N/A	INTRINSIC
low complexity region	1220	1235	N/A	INTRINSIC
low complexity region	1339	1359	N/A	INTRINSIC
low complexity region	1472	1480	N/A	INTRINSIC
low complexity region	1496	1514	N/A	INTRINSIC
low complexity region	1630	1643	N/A	INTRINSIC
low complexity region	1694	1707	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000059836

SMART Domains

Protein: ENSMUSP00000061806
Gene: ENSMUSG00000050382

Domain	Start	End	E-Value	Type
KISc	13	357	2.88e-143	SMART
low complexity region	391	410	N/A	INTRINSIC
Blast:KISc	413	481	1e-19	BLAST
Blast:KISc	482	518	3e-11	BLAST
low complexity region	523	540	N/A	INTRINSIC
low complexity region	543	557	N/A	INTRINSIC
low complexity region	621	636	N/A	INTRINSIC
low complexity region	669	685	N/A	INTRINSIC
Blast:KISc	780	879	2e-15	BLAST
low complexity region	927	944	N/A	INTRINSIC
low complexity region	979	993	N/A	INTRINSIC
low complexity region	1049	1061	N/A	INTRINSIC
coiled coil region	1113	1139	N/A	INTRINSIC
coiled coil region	1186	1205	N/A	INTRINSIC
low complexity region	1293	1304	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000178048

SMART Domains

Protein: ENSMUSP00000136993
Gene: ENSMUSG00000050382

Domain	Start	End	E-Value	Type
KISc	13	357	2.88e-143	SMART
low complexity region	391	410	N/A	INTRINSIC
Blast:KISc	413	481	1e-19	BLAST
Blast:KISc	482	518	3e-11	BLAST
low complexity region	523	540	N/A	INTRINSIC
low complexity region	543	557	N/A	INTRINSIC
low complexity region	621	636	N/A	INTRINSIC
low complexity region	669	685	N/A	INTRINSIC
Blast:KISc	780	879	2e-15	BLAST
low complexity region	908	918	N/A	INTRINSIC
low complexity region	928	945	N/A	INTRINSIC
low complexity region	980	994	N/A	INTRINSIC
low complexity region	1050	1062	N/A	INTRINSIC
coiled coil region	1114	1140	N/A	INTRINSIC
coiled coil region	1187	1206	N/A	INTRINSIC
low complexity region	1294	1305	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000183846

SMART Domains

Protein: ENSMUSP00000139359
Gene: ENSMUSG00000050382

Domain	Start	End	E-Value	Type
KISc	13	357	2.88e-143	SMART
low complexity region	391	410	N/A	INTRINSIC
Blast:KISc	413	481	1e-19	BLAST
Blast:KISc	482	518	3e-11	BLAST
low complexity region	523	540	N/A	INTRINSIC
low complexity region	543	557	N/A	INTRINSIC
low complexity region	621	636	N/A	INTRINSIC
low complexity region	669	685	N/A	INTRINSIC
Blast:KISc	780	879	2e-15	BLAST
low complexity region	908	918	N/A	INTRINSIC
low complexity region	928	945	N/A	INTRINSIC
low complexity region	980	994	N/A	INTRINSIC
low complexity region	1050	1062	N/A	INTRINSIC
coiled coil region	1114	1140	N/A	INTRINSIC
coiled coil region	1187	1206	N/A	INTRINSIC
low complexity region	1294	1305	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000184137

SMART Domains

Protein: ENSMUSP00000139224
Gene: ENSMUSG00000050382

Domain	Start	End	E-Value	Type
KISc	13	357	2.88e-143	SMART
low complexity region	391	410	N/A	INTRINSIC
Blast:KISc	413	481	1e-19	BLAST
Blast:KISc	482	518	3e-11	BLAST
low complexity region	523	540	N/A	INTRINSIC
low complexity region	543	557	N/A	INTRINSIC
low complexity region	621	636	N/A	INTRINSIC
low complexity region	669	685	N/A	INTRINSIC
Blast:KISc	780	879	2e-15	BLAST
low complexity region	927	944	N/A	INTRINSIC
low complexity region	979	993	N/A	INTRINSIC
low complexity region	1049	1061	N/A	INTRINSIC
coiled coil region	1113	1139	N/A	INTRINSIC
coiled coil region	1186	1205	N/A	INTRINSIC
low complexity region	1293	1304	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000206591

Predicted Effect

probably benign
Transcript: ENSMUST00000206622

Coding Region Coverage

1x: 99.8%
3x: 99.6%
10x: 98.6%
20x: 96.4%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Treslin is involved in the initiation of DNA replication (Kumagai et al., 2010 [PubMed 20116089]).[supplied by OMIM, Apr 2010]
PHENOTYPE: Mice homozygous for an ENU-induced allele are mostly hairless, with only a light patch of hair around the face and tail. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 137 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700001K19Rik	TTC	TTCGTC	12: 110,668,450 (GRCm38)		probably benign	Homo
1700001K19Rik	CTT	CTTTTT	12: 110,668,449 (GRCm38)		probably benign	Homo
4930402H24Rik	TCC	TCCCCC	2: 130,770,748 (GRCm38)		probably benign	Het
4930433I11Rik	ACCTC	AC	7: 40,993,056 (GRCm38)		probably benign	Het
4930447C04Rik	AAGT	A	12: 72,881,287 (GRCm38)		probably benign	Homo
4930548H24Rik	GAGAAG	GAG	5: 31,487,373 (GRCm38)		probably benign	Homo
Acbd4	CAG	CAGACTAG	11: 103,104,105 (GRCm38)		probably null	Homo
Ahdc1	CT	CTCTT	4: 133,062,759 (GRCm38)		probably benign	Homo
Alpk3	TCT	TCTGCT	7: 81,077,762 (GRCm38)		probably benign	Het
Anapc4	C	T	5: 52,864,526 (GRCm38)	T650M	probably damaging	Homo
Ankhd1	GGCGGC	GGCGGCTGCGGC	18: 36,560,924 (GRCm38)		probably benign	Het
Ankrd35	TAGC	TAGCAGC	3: 96,683,847 (GRCm38)		probably benign	Homo
Apc	GCCAATAAA	GCCAATAAAACCAATAAA	18: 34,281,997 (GRCm38)		probably benign	Het
Apol6	TTGT	TTGTCTGT	15: 77,051,436 (GRCm38)		probably null	Het
Arhgap30	TGGCCC	TGGCCCTGGCCCAGGCCTTGGCCCCGGCCC	1: 171,405,168 (GRCm38)		probably benign	Het
Arpc1b	GCC	GCCTGTCC	5: 145,126,791 (GRCm38)		probably null	Het
BC051142	GC	GCATC	17: 34,460,077 (GRCm38)		probably benign	Het
BC051142	A	AGCC	17: 34,460,055 (GRCm38)		probably benign	Het
Blm	TCCTCCTCCTCC	TCCTCCTCCTCCACCTCCTCCTCC	7: 80,512,919 (GRCm38)		probably benign	Het
Blm	CT	CTACGT	7: 80,463,773 (GRCm38)		probably null	Homo
Btnl10	GA	GAATA	11: 58,923,930 (GRCm38)		probably benign	Homo
Cacna1f	AGG	AGGCGG	X: 7,620,061 (GRCm38)		probably benign	Het
Calhm3	CG	CGG	19: 47,151,896 (GRCm38)		probably null	Homo
Catsper2	CAT	CATTAT	2: 121,397,782 (GRCm38)		probably benign	Het
Catsper2	C	CTTTTACTTTTTA	2: 121,397,542 (GRCm38)		probably null	Homo
Ccdc15	AC	ACTTTCC	9: 37,315,157 (GRCm38)		probably null	Het
Ccdc162	T	C	10: 41,556,121 (GRCm38)	D1792G	possibly damaging	Het
Ccdc170	CCA	CCATCA	10: 4,561,021 (GRCm38)		probably benign	Het
Ccdc73	TAAG	T	2: 104,991,840 (GRCm38)		probably benign	Homo
Ccdc85c	GCC	GCCCCC	12: 108,274,612 (GRCm38)		probably benign	Het
Cd22	C	T	7: 30,878,082 (GRCm38)	R2H	possibly damaging	Het
Cd80	AGA	AGAGGA	16: 38,486,315 (GRCm38)		probably benign	Homo
Cep89	GACT	G	7: 35,409,641 (GRCm38)		probably benign	Het
Cfap74	A	G	4: 155,415,760 (GRCm38)	D21G	possibly damaging	Homo
Cgref1	T	TCTA	5: 30,933,780 (GRCm38)		probably benign	Homo
Chd4	GCC	GCCACTCCC	6: 125,122,144 (GRCm38)		probably benign	Het
Cnpy3	TCC	TCCACC	17: 46,736,746 (GRCm38)		probably benign	Het
Cnpy3	TCC	TCCCCC	17: 46,736,743 (GRCm38)		probably benign	Het
Cntnap1	AGCCCC	AGCCCCCGCCCC	11: 101,189,581 (GRCm38)		probably benign	Het
Cntnap1	CCCCAG	CCCCAGACCCAG	11: 101,189,589 (GRCm38)		probably benign	Het
Col2a1	C	A	15: 97,988,981 (GRCm38)		probably null	Homo
Cpeb4	T	TGA	11: 31,927,638 (GRCm38)		probably benign	Homo
Cpne1	AGA	AGAGAGA	2: 156,072,025 (GRCm38)		probably null	Homo
Cttnbp2	ATTGCTG	ATTGCTGTTGCTG	6: 18,367,458 (GRCm38)		probably benign	Het
Dhx37	CTGG	C	5: 125,427,530 (GRCm38)		probably benign	Het
Dhx8	CGAGAC	CGAGACGGAGAC	11: 101,738,188 (GRCm38)		probably benign	Homo
Dnah12	G	T	14: 26,849,385 (GRCm38)	G2817V	probably damaging	Homo
Dst	C	A	1: 34,200,964 (GRCm38)	S1798Y	probably damaging	Het
Eif3a	TA	TATTTCA	19: 60,775,290 (GRCm38)		probably benign	Homo
Ermn	TTC	TTCCTC	2: 58,048,078 (GRCm38)		probably benign	Het
Ermn	CTT	CTTGTT	2: 58,048,086 (GRCm38)		probably benign	Het
Fbxo43	GCCTGT	GCCTGTTCCTGT	15: 36,152,094 (GRCm38)		probably benign	Het
Fbxo43	GCCTGT	GCCTGTCCCTGT	15: 36,152,100 (GRCm38)		probably benign	Het
Fbxo43	TGTGCC	TGTGCCAGTGCC	15: 36,152,097 (GRCm38)		probably benign	Het
Fmn1	TCCTCC	TCCTCCCCCTCC	2: 113,525,774 (GRCm38)		probably benign	Het
Fmn1	TCC	TCCTCCACC	2: 113,525,783 (GRCm38)		probably benign	Homo
Foxd3	GGACCCTACGGCCG	GG	4: 99,657,396 (GRCm38)		probably benign	Homo
Frmpd2	G	T	14: 33,511,021 (GRCm38)	L399F	probably damaging	Homo
Gabre	ACTCCGGCTCCGGCTCAGGCTCAGGCTCCGGCTCAGGCTCCGGCTCCGGCTCCGGCTC	ACTCCGGCTCCGGCTCCGGCTCAGGCTCAGGCTCCGGCTCAGGCTCCGGCTCCGGCTCCGGCTC	X: 72,270,042 (GRCm38)		probably benign	Homo
Gbp2b	A	G	3: 142,603,652 (GRCm38)	I175V	probably benign	Het
Gm4340	CAG	CAGAAG	10: 104,196,072 (GRCm38)		probably benign	Het
Gm4340	AGC	AGCGGC	10: 104,196,082 (GRCm38)		probably benign	Het
Gm5114	T	C	7: 39,411,105 (GRCm38)	R107G	probably benign	Het
Gm5114	A	C	7: 39,411,106 (GRCm38)	H106Q	probably benign	Het
Gm9573	T	G	17: 35,622,121 (GRCm38)		probably benign	Homo
H2-Q4	G	A	17: 35,380,405 (GRCm38)	D155N	probably damaging	Het
H2-T10	TGTTTCCCACTG	T	17: 36,120,281 (GRCm38)		probably null	Het
Hist1h1t	GAGAA	GA	13: 23,695,920 (GRCm38)		probably benign	Homo
Ifi203	C	T	1: 173,928,328 (GRCm38)		probably benign	Het
Ifi208	ATGGTG	ATG	1: 173,677,698 (GRCm38)		probably benign	Homo
Ighv5-9	C	T	12: 113,661,877 (GRCm38)	S82N	probably benign	Homo
Il17rd	CGG	CGGTGG	14: 27,082,680 (GRCm38)		probably benign	Het
Il2	AGTGG	AGTGGGGCTTGAGGTGG	3: 37,125,826 (GRCm38)		probably benign	Het
Ipo9	TCC	TCCGCC	1: 135,386,275 (GRCm38)		probably benign	Het
Ipo9	CCT	CCTACT	1: 135,386,279 (GRCm38)		probably null	Het
Isg20l2	AAG	AAGCAG	3: 87,931,712 (GRCm38)		probably benign	Homo
Kmt2b	TCCTCC	TCCTCCCCCTCC	7: 30,586,363 (GRCm38)		probably benign	Het
Kmt2c	TGCTGCTG	TGCTGCTGCTGCTG	5: 25,315,766 (GRCm38)		probably benign	Homo
Krt10	CGCC	CGCCGCC	11: 99,386,199 (GRCm38)		probably benign	Het
Krt10	CCTCCT	CCTCCTACTCCT	11: 99,389,274 (GRCm38)		probably benign	Het
Las1l	GAG	GAGCAG	X: 95,940,820 (GRCm38)		probably benign	Het
Las1l	AGG	AGGCGG	X: 95,940,821 (GRCm38)		probably benign	Het
Lkaaear1	GCTCCAGCTCCAGCTCCAGCTCCA	GCTCCAGCTCCATCTCCAGCTCCAGCTCCAGCTCCA	2: 181,697,579 (GRCm38)		probably benign	Het
Lrch1	A	T	14: 74,819,565 (GRCm38)	C241S	possibly damaging	Het
Lrit3	G	GCTT	3: 129,788,819 (GRCm38)		probably benign	Het
Maml2	GCAGCAGCAACAGCAGCA	GCAGCAGCA	9: 13,621,459 (GRCm38)		probably benign	Homo
Mast4	T	TTTC	13: 102,734,862 (GRCm38)		probably benign	Het
Med12l	AGC	AGCGGC	3: 59,275,982 (GRCm38)		probably benign	Het
Noc2l	TGC	TGCAGC	4: 156,240,096 (GRCm38)		probably benign	Het
Nrg3	G	GACATTT	14: 38,397,273 (GRCm38)		probably benign	Homo
Olfr635	TCC	TCCC	7: 103,979,903 (GRCm38)		probably null	Het
Padi3	TCTCAC	TC	4: 140,792,972 (GRCm38)		probably benign	Homo
Park2	G	A	17: 11,854,763 (GRCm38)	V323M	probably damaging	Het
Patl2	GCT	GCTTCT	2: 122,126,135 (GRCm38)		probably benign	Het
Pdik1l	TTTT	TTTTGTTTTTGGTTT	4: 134,279,374 (GRCm38)		probably null	Homo
Pik3c2g	AG	AGAGGG	6: 139,635,656 (GRCm38)		probably null	Homo
Plekhs1	T	TTCAGACCTCCCC	19: 56,479,858 (GRCm38)		probably benign	Het
Prkd3	G	T	17: 78,975,820 (GRCm38)		probably null	Homo
Prr13	TCC	TCCCCC	15: 102,462,177 (GRCm38)		probably benign	Homo
Prrc2b	G	A	2: 32,221,167 (GRCm38)	A1852T	probably damaging	Homo
Ptms	CTT	CTTTTT	6: 124,914,458 (GRCm38)		probably benign	Homo
Rtl1	TTCCTCTTCCTCCTC	TTCCTC	12: 109,591,198 (GRCm38)		probably benign	Homo
Scaf4	TGCGGC	TGC	16: 90,229,854 (GRCm38)		probably benign	Homo
Serac1	T	A	17: 6,070,808 (GRCm38)	K70N	probably damaging	Homo
Six3	CGG	CGGTGG	17: 85,621,368 (GRCm38)		probably benign	Het
Sry	GTG	GTGCTG	Y: 2,662,837 (GRCm38)		probably benign	Homo
Stard8	GGAAGA	GGAAGAAGA	X: 99,066,505 (GRCm38)		probably benign	Het
Supt20	TTCAGCA	TTCAGCATCAGCA	3: 54,727,647 (GRCm38)		probably benign	Het
Supt20	AGCAGC	AGCAGCGGCAGC	3: 54,727,662 (GRCm38)		probably benign	Het
Supt20	CAGCAG	CAGCAGTAGCAG	3: 54,727,664 (GRCm38)		probably null	Het
Sytl1	CTCT	C	4: 133,256,993 (GRCm38)		probably benign	Homo
Tcof1	AGC	AGCGGC	18: 60,835,742 (GRCm38)		probably benign	Het
Tdpoz2	T	TCA	3: 93,651,615 (GRCm38)		probably null	Homo
Tert	GCC	GCCAAGGGTTCC	13: 73,648,302 (GRCm38)		probably benign	Homo
Tfeb	GCA	GCAACA	17: 47,786,094 (GRCm38)		probably benign	Het
Tnfaip8	ACACACACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC	AC	18: 50,046,839 (GRCm38)		probably null	Homo
Tnfrsf9	T	TGCC	4: 150,934,395 (GRCm38)		probably benign	Homo
Tob1	GCA	GCAACA	11: 94,214,464 (GRCm38)		probably benign	Het
Tob1	CA	CAGTA	11: 94,214,477 (GRCm38)		probably null	Het
Trav15-2-dv6-2	GGGAG	GGGAGGAG	14: 53,649,750 (GRCm38)		probably benign	Homo
Triobp	TCGTCG	TCGTCGTCG	15: 78,993,387 (GRCm38)		probably benign	Homo
Tsen2	AGG	AGGGGG	6: 115,560,069 (GRCm38)		probably benign	Het
Ubtf	TCC	TCCGCC	11: 102,306,956 (GRCm38)		probably benign	Het
Ubtf	CTCGTCGTC	CTCGTCGTCGTC	11: 102,306,958 (GRCm38)		probably benign	Het
Vars	TGG	TGGAGTCCTGGGCGG	17: 35,015,989 (GRCm38)		probably benign	Homo
Vmn1r171	C	T	7: 23,632,680 (GRCm38)	A110V	probably benign	Het
Vmn2r31	G	T	7: 7,384,608 (GRCm38)	Q655K	probably damaging	Het
Vmn2r87	C	T	10: 130,478,714 (GRCm38)	M334I	probably benign	Homo
Zc3h13	CG	CGAGATGTGTG	14: 75,323,610 (GRCm38)		probably benign	Het
Zc3h13	AGATGTGCG	AGATGTGCGGGATGTGCG	14: 75,323,603 (GRCm38)		probably benign	Het
Zfp282	GGC	GGCCGC	6: 47,904,797 (GRCm38)		probably benign	Het
Zfp384	AGGC	AGGCCCAGGCCCCGGC	6: 125,036,493 (GRCm38)		probably benign	Het
Zfp459	TGA	TGAGCGA	13: 67,408,274 (GRCm38)		probably null	Homo
Zfp462	CCACC	CCACCTCAGCCACAGTCACC	4: 55,009,758 (GRCm38)		probably benign	Het
Zfp462	GCCACC	GCCACCTCAGCCACAACCACC	4: 55,009,757 (GRCm38)		probably benign	Het
Zfp598	CACCAC	CACCACAACCAC	17: 24,680,775 (GRCm38)		probably benign	Het
Zfp831	CCT	CCTGCT	2: 174,645,481 (GRCm38)		probably benign	Het

Other mutations in Ticrr

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00087:Ticrr	APN	7	79,677,283 (GRCm38)	missense	probably damaging	1.00
IGL00596:Ticrr	APN	7	79,677,293 (GRCm38)	missense	probably damaging	1.00
IGL01327:Ticrr	APN	7	79,694,461 (GRCm38)	missense	probably benign	0.00
IGL01525:Ticrr	APN	7	79,682,449 (GRCm38)	missense	probably damaging	1.00
IGL01565:Ticrr	APN	7	79,694,548 (GRCm38)	missense	probably benign
IGL01936:Ticrr	APN	7	79,694,549 (GRCm38)	missense	probably benign	0.11
IGL02160:Ticrr	APN	7	79,694,019 (GRCm38)	missense	probably benign	0.29
IGL02246:Ticrr	APN	7	79,675,328 (GRCm38)	missense	probably damaging	1.00
IGL02487:Ticrr	APN	7	79,683,021 (GRCm38)	missense	possibly damaging	0.86
IGL02593:Ticrr	APN	7	79,695,466 (GRCm38)	missense	probably damaging	0.99
IGL02970:Ticrr	APN	7	79,695,171 (GRCm38)	missense	probably benign	0.01
PIT4305001:Ticrr	UTSW	7	79,679,023 (GRCm38)	missense	possibly damaging	0.95
PIT4791001:Ticrr	UTSW	7	79,669,638 (GRCm38)	missense	possibly damaging	0.92
R0016:Ticrr	UTSW	7	79,693,792 (GRCm38)	missense	probably benign	0.01
R0062:Ticrr	UTSW	7	79,667,906 (GRCm38)	missense	probably benign	0.01
R0062:Ticrr	UTSW	7	79,667,906 (GRCm38)	missense	probably benign	0.01
R0067:Ticrr	UTSW	7	79,677,410 (GRCm38)	missense	probably damaging	1.00
R0067:Ticrr	UTSW	7	79,677,410 (GRCm38)	missense	probably damaging	1.00
R0362:Ticrr	UTSW	7	79,677,340 (GRCm38)	missense	probably damaging	1.00
R0482:Ticrr	UTSW	7	79,694,488 (GRCm38)	missense	probably damaging	0.99
R0595:Ticrr	UTSW	7	79,695,563 (GRCm38)	missense	possibly damaging	0.94
R1118:Ticrr	UTSW	7	79,693,953 (GRCm38)	missense	probably benign	0.23
R1119:Ticrr	UTSW	7	79,693,953 (GRCm38)	missense	probably benign	0.23
R1572:Ticrr	UTSW	7	79,681,824 (GRCm38)	missense	probably damaging	1.00
R1658:Ticrr	UTSW	7	79,695,549 (GRCm38)	missense	possibly damaging	0.57
R1757:Ticrr	UTSW	7	79,679,046 (GRCm38)	nonsense	probably null
R1757:Ticrr	UTSW	7	79,675,323 (GRCm38)	missense	probably damaging	0.99
R1862:Ticrr	UTSW	7	79,695,207 (GRCm38)	missense	probably damaging	1.00
R1869:Ticrr	UTSW	7	79,679,135 (GRCm38)	missense	probably damaging	1.00
R1938:Ticrr	UTSW	7	79,675,394 (GRCm38)	missense	probably damaging	0.98
R1966:Ticrr	UTSW	7	79,694,735 (GRCm38)	nonsense	probably null
R2006:Ticrr	UTSW	7	79,694,073 (GRCm38)	missense	possibly damaging	0.93
R2178:Ticrr	UTSW	7	79,665,685 (GRCm38)	missense	probably benign	0.12
R3404:Ticrr	UTSW	7	79,694,791 (GRCm38)	missense	probably benign	0.06
R3405:Ticrr	UTSW	7	79,694,791 (GRCm38)	missense	probably benign	0.06
R3941:Ticrr	UTSW	7	79,693,697 (GRCm38)	intron	probably benign
R3950:Ticrr	UTSW	7	79,682,069 (GRCm38)	missense	probably damaging	1.00
R3951:Ticrr	UTSW	7	79,682,069 (GRCm38)	missense	probably damaging	1.00
R3952:Ticrr	UTSW	7	79,682,069 (GRCm38)	missense	probably damaging	1.00
R4967:Ticrr	UTSW	7	79,660,410 (GRCm38)	missense	probably damaging	0.99
R4972:Ticrr	UTSW	7	79,669,668 (GRCm38)	missense	probably damaging	0.98
R5259:Ticrr	UTSW	7	79,694,723 (GRCm38)	missense	probably benign	0.01
R5272:Ticrr	UTSW	7	79,669,605 (GRCm38)	missense	probably benign	0.44
R5374:Ticrr	UTSW	7	79,690,942 (GRCm38)	nonsense	probably null
R5480:Ticrr	UTSW	7	79,660,809 (GRCm38)	missense	probably damaging	1.00
R5568:Ticrr	UTSW	7	79,695,296 (GRCm38)	nonsense	probably null
R5568:Ticrr	UTSW	7	79,689,967 (GRCm38)	critical splice donor site	probably null
R5588:Ticrr	UTSW	7	79,679,105 (GRCm38)	missense	probably damaging	1.00
R5698:Ticrr	UTSW	7	79,679,133 (GRCm38)	missense	probably benign
R5879:Ticrr	UTSW	7	79,696,690 (GRCm38)	missense	probably benign	0.12
R5980:Ticrr	UTSW	7	79,660,955 (GRCm38)	missense	probably damaging	0.99
R6128:Ticrr	UTSW	7	79,693,968 (GRCm38)	missense	probably damaging	1.00
R6277:Ticrr	UTSW	7	79,694,696 (GRCm38)	missense	probably benign	0.00
R6335:Ticrr	UTSW	7	79,694,283 (GRCm38)	splice site	probably null
R6866:Ticrr	UTSW	7	79,693,957 (GRCm38)	missense	possibly damaging	0.47
R6905:Ticrr	UTSW	7	79,665,850 (GRCm38)	missense	probably benign	0.00
R6923:Ticrr	UTSW	7	79,691,853 (GRCm38)	missense	probably damaging	0.98
R6962:Ticrr	UTSW	7	79,665,897 (GRCm38)	missense	possibly damaging	0.84
R7232:Ticrr	UTSW	7	79,693,742 (GRCm38)	missense	probably damaging	0.96
R7285:Ticrr	UTSW	7	79,660,862 (GRCm38)	missense	possibly damaging	0.93
R7385:Ticrr	UTSW	7	79,691,849 (GRCm38)	missense	possibly damaging	0.93
R7426:Ticrr	UTSW	7	79,693,986 (GRCm38)	missense	probably benign
R7583:Ticrr	UTSW	7	79,696,739 (GRCm38)	nonsense	probably null
R7749:Ticrr	UTSW	7	79,679,096 (GRCm38)	missense	possibly damaging	0.94
R7863:Ticrr	UTSW	7	79,682,012 (GRCm38)	missense	possibly damaging	0.92
R7899:Ticrr	UTSW	7	79,669,485 (GRCm38)	missense	probably benign	0.23
R7935:Ticrr	UTSW	7	79,681,836 (GRCm38)	missense	probably damaging	0.99
R8005:Ticrr	UTSW	7	79,694,048 (GRCm38)	missense	probably damaging	0.98
R8080:Ticrr	UTSW	7	79,684,264 (GRCm38)	splice site	probably null
R8181:Ticrr	UTSW	7	79,660,980 (GRCm38)	missense	possibly damaging	0.92
R8349:Ticrr	UTSW	7	79,694,680 (GRCm38)	missense	probably benign	0.27
R8410:Ticrr	UTSW	7	79,667,675 (GRCm38)	missense	probably damaging	0.98
R8449:Ticrr	UTSW	7	79,694,680 (GRCm38)	missense	probably benign	0.27
R9073:Ticrr	UTSW	7	79,667,931 (GRCm38)	missense	probably benign	0.01
R9090:Ticrr	UTSW	7	79,660,856 (GRCm38)	missense	possibly damaging	0.85
R9271:Ticrr	UTSW	7	79,660,856 (GRCm38)	missense	possibly damaging	0.85
R9287:Ticrr	UTSW	7	79,693,768 (GRCm38)	missense	possibly damaging	0.89
R9368:Ticrr	UTSW	7	79,680,987 (GRCm38)	missense	probably damaging	0.99
R9469:Ticrr	UTSW	7	79,694,763 (GRCm38)	missense	probably benign	0.03
R9502:Ticrr	UTSW	7	79,693,849 (GRCm38)	missense	probably benign
R9614:Ticrr	UTSW	7	79,696,006 (GRCm38)	missense	probably damaging	1.00
R9761:Ticrr	UTSW	7	79,695,565 (GRCm38)	missense	probably damaging	1.00
R9779:Ticrr	UTSW	7	79,679,054 (GRCm38)	missense	probably benign	0.37

Predicted Primers

PCR Primer
(F):5'- GTGTCTGACCCCTATAAGATACTCC -3'
(R):5'- TCTCCGAAGCTTGGATGGTG -3'

Sequencing Primer
(F):5'- TGACCCCTATAAGATACTCCTTCAG -3'
(R):5'- AAGGTGGTATGGGGCAGGTC -3'

Posted On

2018-04-05