Incidental Mutation 'FR4449:Cul9'
| ID |
511547 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cul9
|
| Ensembl Gene |
ENSMUSG00000040327 |
| Gene Name |
cullin 9 |
| Synonyms |
Parc, 1810035I07Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.227)
|
| Stock # |
FR4449 ()
|
| Quality Score |
167.468 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
46811535-46857314 bp(-) (GRCm39) |
| Type of Mutation |
small insertion (1 aa in frame mutation) |
| DNA Base Change (assembly) |
TCC to TCCGCC
at 46811782 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138418
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046497]
[ENSMUST00000066026]
[ENSMUST00000182485]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000046497
|
| SMART Domains |
Protein: ENSMUSP00000045283
Gene: ENSMUSG00000040658
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nuc_deoxyrib_tr
|
12 |
144 |
3.8e-21 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000066026
|
| SMART Domains |
Protein: ENSMUSP00000067736
Gene: ENSMUSG00000040327
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
46 |
61 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
131 |
N/A |
INTRINSIC |
|
low complexity region
|
345 |
357 |
N/A |
INTRINSIC |
|
Pfam:Cul7
|
367 |
441 |
1e-35 |
PFAM |
|
low complexity region
|
447 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
525 |
540 |
N/A |
INTRINSIC |
|
low complexity region
|
845 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
873 |
880 |
N/A |
INTRINSIC |
|
APC10
|
1166 |
1325 |
1.97e-56 |
SMART |
|
low complexity region
|
1437 |
1450 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1578 |
N/A |
INTRINSIC |
|
low complexity region
|
1646 |
1671 |
N/A |
INTRINSIC |
|
Cullin_Nedd8
|
1867 |
1950 |
7.55e-6 |
SMART |
|
Blast:RING
|
2074 |
2122 |
2e-13 |
BLAST |
|
IBR
|
2144 |
2207 |
8.99e-14 |
SMART |
|
IBR
|
2228 |
2283 |
4.66e-2 |
SMART |
|
low complexity region
|
2503 |
2520 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000181301
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182315
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182485
|
| SMART Domains |
Protein: ENSMUSP00000138418
Gene: ENSMUSG00000040327
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
46 |
61 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
131 |
N/A |
INTRINSIC |
|
low complexity region
|
345 |
357 |
N/A |
INTRINSIC |
|
Pfam:Cul7
|
367 |
442 |
1.4e-33 |
PFAM |
|
low complexity region
|
447 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
525 |
540 |
N/A |
INTRINSIC |
|
low complexity region
|
845 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
873 |
880 |
N/A |
INTRINSIC |
|
APC10
|
1166 |
1325 |
1.97e-56 |
SMART |
|
low complexity region
|
1437 |
1450 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1578 |
N/A |
INTRINSIC |
|
low complexity region
|
1646 |
1671 |
N/A |
INTRINSIC |
|
Cullin_Nedd8
|
1867 |
1950 |
7.55e-6 |
SMART |
|
Blast:RING
|
2074 |
2122 |
3e-13 |
BLAST |
|
IBR
|
2144 |
2207 |
8.99e-14 |
SMART |
|
IBR
|
2228 |
2283 |
4.66e-2 |
SMART |
|
coiled coil region
|
2461 |
2497 |
N/A |
INTRINSIC |
|
low complexity region
|
2513 |
2530 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182530
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183078
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183312
|
| Coding Region Coverage |
- 1x: 99.7%
- 3x: 99.5%
- 10x: 98.3%
- 20x: 95.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased body weight, increased incidence of tumors, and decreased cellular sensitivity to radiation-induced apoptosis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 128 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Akap9 |
GGTATTGCATTTCTTATCT |
G |
5: 4,031,214 (GRCm39) |
|
probably benign |
Homo |
| Amfr |
C |
G |
8: 94,731,787 (GRCm39) |
G30R |
probably damaging |
Homo |
| Anxa7 |
C |
T |
14: 20,519,479 (GRCm39) |
G113E |
probably damaging |
Homo |
| Apc |
AGC |
AGCCAATAACGC |
18: 34,415,058 (GRCm39) |
|
probably benign |
Het |
| Apc |
AATAAAGC |
AATAAAGCCGATAAAGC |
18: 34,415,053 (GRCm39) |
|
probably benign |
Het |
| Apol6 |
TTT |
TTTGATT |
15: 76,935,643 (GRCm39) |
|
probably null |
Homo |
| Arid1b |
CGG |
CGGTGG |
17: 5,045,864 (GRCm39) |
|
probably benign |
Het |
| B430218F22Rik |
CGGCG |
CGGCGATGGCG |
13: 118,523,387 (GRCm39) |
|
probably benign |
Homo |
| Blm |
CCTCCTCCTCCTCCTCCTCCTCCT |
CCTCCTCCTCCTTCTCCTCCTCCTCCTCCTCCTCCT |
7: 80,162,656 (GRCm39) |
|
probably benign |
Het |
| Brd2 |
CTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
CAAAAAAAAAAAAAAA |
17: 34,335,310 (GRCm39) |
|
probably benign |
Het |
| Btnl10 |
AAG |
AAGGAG |
11: 58,814,754 (GRCm39) |
|
probably benign |
Homo |
| Cacna1a |
ACC |
ACCCCC |
8: 85,365,343 (GRCm39) |
|
probably benign |
Het |
| Cacna1a |
ACC |
ACCGCC |
8: 85,365,352 (GRCm39) |
|
probably benign |
Het |
| Cacna1a |
ACC |
ACCCCC |
8: 85,365,349 (GRCm39) |
|
probably benign |
Het |
| Calhm1 |
TGGC |
TGGCTGTGGCTGCGGC |
19: 47,129,713 (GRCm39) |
|
probably benign |
Het |
| Ccdc15 |
C |
CTTTAT |
9: 37,226,454 (GRCm39) |
|
probably null |
Het |
| Ccdc85c |
CCG |
CCGACG |
12: 108,240,875 (GRCm39) |
|
probably benign |
Het |
| Ccnk |
TTCCCAC |
T |
12: 108,168,766 (GRCm39) |
|
probably benign |
Het |
| Cdhr2 |
AGTC |
AGTCGTC |
13: 54,873,737 (GRCm39) |
|
probably benign |
Homo |
| Cdk15 |
A |
ATCTAAAAGG |
1: 59,296,982 (GRCm39) |
|
probably benign |
Homo |
| Cdx1 |
GCTG |
GCTGCTCCTG |
18: 61,152,953 (GRCm39) |
|
probably benign |
Het |
| Cfap46 |
T |
C |
7: 139,218,711 (GRCm39) |
|
probably benign |
Homo |
| Cgref1 |
TTC |
TTCGTC |
5: 31,091,120 (GRCm39) |
|
probably benign |
Het |
| Cgref1 |
CTT |
CTTATT |
5: 31,091,122 (GRCm39) |
|
probably null |
Homo |
| Cluh |
G |
GACTGAA |
11: 74,560,358 (GRCm39) |
|
probably benign |
Het |
| Cntnap1 |
AGCCCC |
AGCCCCCGCCCC |
11: 101,080,395 (GRCm39) |
|
probably benign |
Het |
| Cntnap1 |
AGCC |
AGCCCCCGCC |
11: 101,080,419 (GRCm39) |
|
probably benign |
Het |
| Cpne1 |
CCTACT |
CCT |
2: 155,915,422 (GRCm39) |
|
probably benign |
Homo |
| Cracdl |
T |
A |
1: 37,664,116 (GRCm39) |
E594V |
probably benign |
Homo |
| Cracdl |
C |
A |
1: 37,664,117 (GRCm39) |
E594* |
probably null |
Homo |
| Cttnbp2 |
CTGCTG |
CTGCTGTTGCTG |
6: 18,367,461 (GRCm39) |
|
probably benign |
Het |
| Dbr1 |
AGGAGG |
AGGAGGGGGAGG |
9: 99,465,727 (GRCm39) |
|
probably benign |
Het |
| Dbr1 |
AGGAGG |
AGGAGGCGGAGG |
9: 99,465,739 (GRCm39) |
|
probably benign |
Het |
| Dbr1 |
GGAGGA |
GGAGGAAGAGGA |
9: 99,465,749 (GRCm39) |
|
probably benign |
Het |
| Dhx8 |
CG |
CGAGACAG |
11: 101,629,020 (GRCm39) |
|
probably benign |
Homo |
| Dhx8 |
CG |
CGAGACAG |
11: 101,629,032 (GRCm39) |
|
probably benign |
Het |
| Dhx8 |
G |
GAGACCC |
11: 101,629,033 (GRCm39) |
|
probably benign |
Het |
| Dhx8 |
AGACCG |
AGACCGTGACCG |
11: 101,629,010 (GRCm39) |
|
probably benign |
Homo |
| Dhx8 |
AGACCGGGACCGGGACCGGGACCGGGAC |
AGACCGGGACCGGGAC |
11: 101,629,016 (GRCm39) |
|
probably benign |
Het |
| Dspp |
CGACAGCAGTGACAGCAGCGACAGCAGCGACAGCAGTGACAGCAG |
CGACAGCAGCGACAGCAGCGACAGCAGTGACAGCAG |
5: 104,326,254 (GRCm39) |
|
probably benign |
Het |
| Dusp10 |
G |
T |
1: 183,769,253 (GRCm39) |
C73F |
probably damaging |
Homo |
| Erich3 |
GA |
GAGAA |
3: 154,469,150 (GRCm39) |
|
probably benign |
Homo |
| Ermn |
CTT |
CTTGTT |
2: 57,938,086 (GRCm39) |
|
probably benign |
Het |
| Fgd6 |
GGAT |
G |
10: 93,880,182 (GRCm39) |
|
probably benign |
Homo |
| G530012D18Rik |
GAGAGAGAGAGAGAGAGACAGAGA |
GAGAGA |
1: 85,504,901 (GRCm39) |
|
probably benign |
Homo |
| Gar1 |
GCCGCCTCCGCC |
GCCGCC |
3: 129,624,353 (GRCm39) |
|
probably benign |
Homo |
| Gatad2b |
AGAC |
A |
3: 90,249,224 (GRCm39) |
|
probably benign |
Het |
| Gigyf2 |
C |
T |
1: 87,356,307 (GRCm39) |
|
probably benign |
Het |
| Gm16519 |
A |
AGAT |
17: 71,236,333 (GRCm39) |
|
probably benign |
Homo |
| Gm4340 |
AGC |
AGCGGC |
10: 104,031,946 (GRCm39) |
|
probably benign |
Het |
| Gm4340 |
GCA |
GCATCA |
10: 104,031,947 (GRCm39) |
|
probably benign |
Het |
| Gm4340 |
AGC |
AGCGGC |
10: 104,031,943 (GRCm39) |
|
probably benign |
Het |
| Gpatch11 |
AGGAAG |
AGGAAGCGGAAG |
17: 79,149,597 (GRCm39) |
|
probably benign |
Het |
| Gpatch11 |
GAAGAG |
GAAGAGCAAGAG |
17: 79,149,605 (GRCm39) |
|
probably benign |
Het |
| Gpatch11 |
GG |
GGCAGACG |
17: 79,149,610 (GRCm39) |
|
probably benign |
Het |
| Hoxa10 |
T |
A |
6: 52,211,166 (GRCm39) |
Q250L |
possibly damaging |
Homo |
| Igkv12-89 |
GCA |
GCAGCAGCAACA |
6: 68,812,264 (GRCm39) |
|
probably benign |
Homo |
| Igsf10 |
G |
A |
3: 59,226,531 (GRCm39) |
R2381C |
probably damaging |
Homo |
| Il17rd |
GGC |
GGCAGC |
14: 26,804,635 (GRCm39) |
|
probably benign |
Het |
| Ints5 |
G |
A |
19: 8,874,594 (GRCm39) |
R851Q |
probably benign |
Het |
| Isg20l2 |
AGA |
AGAGGA |
3: 87,839,020 (GRCm39) |
|
probably benign |
Het |
| Kcng4 |
G |
T |
8: 120,360,258 (GRCm39) |
Y39* |
probably null |
Homo |
| Kifc5b |
A |
C |
17: 27,143,191 (GRCm39) |
E321A |
probably benign |
Het |
| Klra2 |
TCCACAG |
TCCACAGAAACCCACAG |
6: 131,198,809 (GRCm39) |
|
probably null |
Homo |
| Kmt2b |
TCCTCC |
TCCTCCCCCTCC |
7: 30,285,794 (GRCm39) |
|
probably benign |
Het |
| Kmt2b |
CCTCCT |
CCTCCTGCTCCT |
7: 30,285,786 (GRCm39) |
|
probably benign |
Het |
| Kmt2b |
TCCTCC |
TCCTCCACCTCC |
7: 30,285,791 (GRCm39) |
|
probably benign |
Het |
| Krt10 |
ACC |
ACCACCTCC |
11: 99,280,093 (GRCm39) |
|
probably benign |
Het |
| Las1l |
GA |
GAGAA |
X: 94,984,438 (GRCm39) |
|
probably benign |
Het |
| Lce1m |
AC |
ACTGCTGCTGCCGC |
3: 92,925,459 (GRCm39) |
|
probably benign |
Het |
| Leo1 |
GTACCATGCA |
G |
9: 75,357,855 (GRCm39) |
|
probably benign |
Het |
| Lkaaear1 |
CA |
CATCTCCAGCTCTA |
2: 181,339,364 (GRCm39) |
|
probably benign |
Het |
| Maml2 |
ACAGCAGCAGCAACAGCAGCAGCAGCAGCA |
ACAGCAACAGCAGCAGCAGCAGCA |
9: 13,532,752 (GRCm39) |
|
probably benign |
Homo |
| Med12l |
CAG |
CAGTAG |
3: 59,183,384 (GRCm39) |
|
probably null |
Het |
| Mgat4e |
GTCGTAGTCATCGT |
GTCGT |
1: 134,468,735 (GRCm39) |
|
probably benign |
Homo |
| Mn1 |
GCA |
GCAACA |
5: 111,567,576 (GRCm39) |
|
probably benign |
Het |
| Morn4 |
AGGCAGTGAG |
AGGCAGTGAGTCTGGCAGTGAG |
19: 42,064,548 (GRCm39) |
|
probably benign |
Het |
| Nat8f2 |
T |
A |
6: 85,844,668 (GRCm39) |
L231F |
possibly damaging |
Homo |
| Noc2l |
C |
CTGA |
4: 156,324,558 (GRCm39) |
|
probably benign |
Het |
| Nrg3 |
T |
TAGACAC |
14: 38,119,228 (GRCm39) |
|
probably benign |
Het |
| Or8b41 |
A |
G |
9: 38,054,484 (GRCm39) |
I13V |
probably benign |
Homo |
| Piezo1 |
G |
A |
8: 123,222,308 (GRCm39) |
R503W |
probably damaging |
Homo |
| Pih1d2 |
CTCTTGCGAGGATC |
CTC |
9: 50,532,927 (GRCm39) |
|
probably null |
Homo |
| Pik3ap1 |
G |
GGAA |
19: 41,270,385 (GRCm39) |
|
probably benign |
Het |
| Ppp1r3f |
C |
A |
X: 7,426,575 (GRCm39) |
G562V |
probably damaging |
Homo |
| Ptms |
TTC |
TTCGTC |
6: 124,891,422 (GRCm39) |
|
probably benign |
Het |
| Ptpn23 |
G |
T |
9: 110,216,701 (GRCm39) |
P1052T |
probably benign |
Homo |
| Qrich2 |
AACT |
A |
11: 116,347,025 (GRCm39) |
|
probably benign |
Homo |
| Raet1d |
A |
ATATCCTCTCTGG |
10: 22,246,814 (GRCm39) |
|
probably benign |
Het |
| Rbm33 |
AGCAGCAGCAGCACCAGCCGCAGCAGCAGCA |
AGCAGCAGCAGCA |
5: 28,599,166 (GRCm39) |
|
probably benign |
Homo |
| Rrbp1 |
TGCTTCTCAAAGGTGGCTGCCTTGGCTTC |
TGCTTC |
2: 143,809,376 (GRCm39) |
|
probably null |
Het |
| Sbp |
CAACAAAGATGCTGA |
CAACAAAGATGCTGAGAACAAAGATGCTGA |
17: 24,164,338 (GRCm39) |
|
probably benign |
Het |
| Setd1a |
G |
A |
7: 127,384,498 (GRCm39) |
|
probably benign |
Het |
| Sfswap |
CCCACTCAG |
CCCACTCAGTCCACTCAG |
5: 129,646,812 (GRCm39) |
|
probably benign |
Het |
| Sfswap |
CCACTCAGC |
CCACTCAGCTCACTCAGC |
5: 129,646,813 (GRCm39) |
|
probably benign |
Het |
| Sh3pxd2b |
T |
TGTCTGC |
11: 32,373,065 (GRCm39) |
|
probably benign |
Homo |
| Six3 |
CGG |
CGGGGG |
17: 85,928,790 (GRCm39) |
|
probably benign |
Het |
| Slc12a1 |
C |
CTTTGGCCACAACACG |
2: 124,996,136 (GRCm39) |
|
probably benign |
Homo |
| Slc26a8 |
CTCTCTG |
C |
17: 28,857,290 (GRCm39) |
|
probably benign |
Het |
| Spata31h1 |
TTCAGT |
TT |
10: 82,121,303 (GRCm39) |
|
probably null |
Homo |
| Srebf2 |
G |
T |
15: 82,069,536 (GRCm39) |
A693S |
probably damaging |
Homo |
| Sry |
ACTG |
ACTGCTG |
Y: 2,662,818 (GRCm39) |
|
probably benign |
Het |
| Sry |
TGCTG |
TGCTGCTG |
Y: 2,662,832 (GRCm39) |
|
probably benign |
Homo |
| Ston1 |
G |
A |
17: 88,942,953 (GRCm39) |
V120M |
probably benign |
Homo |
| Supt20 |
CAGCAG |
CAGCAGGAGCAG |
3: 54,635,070 (GRCm39) |
|
probably benign |
Het |
| Tbl3 |
TG |
TGTGG |
17: 24,921,518 (GRCm39) |
|
probably benign |
Homo |
| Tctn3 |
AG |
AGAAGCCG |
19: 40,595,646 (GRCm39) |
|
probably benign |
Het |
| Tesk1 |
CCC |
CCCACC |
4: 43,447,002 (GRCm39) |
|
probably benign |
Homo |
| Tmc2 |
T |
G |
2: 130,082,116 (GRCm39) |
V433G |
probably damaging |
Het |
| Tmprss13 |
G |
A |
9: 45,239,856 (GRCm39) |
A55T |
unknown |
Het |
| Tnfaip8 |
ACACACACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC |
AC |
18: 50,179,906 (GRCm39) |
|
probably null |
Homo |
| Tob1 |
CAG |
CAGAAG |
11: 94,105,294 (GRCm39) |
|
probably benign |
Het |
| Tob1 |
AGC |
AGCCGC |
11: 94,105,301 (GRCm39) |
|
probably benign |
Het |
| Tpsab1 |
TTGCACCTCCT |
TT |
17: 25,562,756 (GRCm39) |
|
probably benign |
Homo |
| Triobp |
GTC |
GTCTTC |
15: 78,877,589 (GRCm39) |
|
probably benign |
Het |
| Ubtf |
CCT |
CCTACT |
11: 102,197,774 (GRCm39) |
|
probably null |
Het |
| Vps13b |
G |
T |
15: 35,847,103 (GRCm39) |
A2629S |
probably damaging |
Homo |
| Xpnpep3 |
G |
C |
15: 81,311,623 (GRCm39) |
D110H |
possibly damaging |
Het |
| Zc3h13 |
CGAGATGTG |
CGAGATGTGTGAGATGTG |
14: 75,561,041 (GRCm39) |
|
probably null |
Homo |
| Zfhx3 |
GCAACAGCA |
GCAACAGCAACAACAGCA |
8: 109,682,726 (GRCm39) |
|
probably benign |
Homo |
| Zfp26 |
C |
A |
9: 20,349,842 (GRCm39) |
A241S |
probably benign |
Homo |
| Zfp335 |
CTC |
CTCATC |
2: 164,749,397 (GRCm39) |
|
probably benign |
Het |
| Zfp335 |
CTCT |
CTCTTCT |
2: 164,749,403 (GRCm39) |
|
probably benign |
Het |
| Zfp598 |
ACCACC |
ACCACCTCCACC |
17: 24,899,750 (GRCm39) |
|
probably benign |
Het |
| Zfp598 |
ACCACC |
ACCACCCCCACC |
17: 24,899,759 (GRCm39) |
|
probably benign |
Het |
| Zfp831 |
TCC |
TCCACC |
2: 174,487,264 (GRCm39) |
|
probably benign |
Het |
| Zfp831 |
CTC |
CTCGTC |
2: 174,487,275 (GRCm39) |
|
probably benign |
Het |
| Zfp978 |
G |
T |
4: 147,475,401 (GRCm39) |
S316I |
probably benign |
Het |
|
| Other mutations in Cul9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00087:Cul9
|
APN |
17 |
46,836,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00330:Cul9
|
APN |
17 |
46,821,767 (GRCm39) |
splice site |
probably benign |
|
|
IGL00726:Cul9
|
APN |
17 |
46,839,022 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01020:Cul9
|
APN |
17 |
46,849,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01358:Cul9
|
APN |
17 |
46,849,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01410:Cul9
|
APN |
17 |
46,839,572 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01781:Cul9
|
APN |
17 |
46,850,230 (GRCm39) |
missense |
probably benign |
|
|
IGL01873:Cul9
|
APN |
17 |
46,813,378 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02117:Cul9
|
APN |
17 |
46,851,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02300:Cul9
|
APN |
17 |
46,831,958 (GRCm39) |
splice site |
probably benign |
|
|
IGL02426:Cul9
|
APN |
17 |
46,834,184 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02427:Cul9
|
APN |
17 |
46,813,558 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02496:Cul9
|
APN |
17 |
46,851,302 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL03008:Cul9
|
APN |
17 |
46,813,623 (GRCm39) |
splice site |
probably benign |
|
|
IGL03059:Cul9
|
APN |
17 |
46,849,913 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03302:Cul9
|
APN |
17 |
46,837,566 (GRCm39) |
missense |
probably damaging |
0.98 |
|
bottlenose
|
UTSW |
17 |
46,811,770 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
flipper
|
UTSW |
17 |
46,836,818 (GRCm39) |
missense |
probably benign |
0.05 |
|
orca
|
UTSW |
17 |
46,836,061 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4340:Cul9
|
UTSW |
17 |
46,811,779 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Cul9
|
UTSW |
17 |
46,811,784 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Cul9
|
UTSW |
17 |
46,811,772 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Cul9
|
UTSW |
17 |
46,811,779 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Cul9
|
UTSW |
17 |
46,811,776 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Cul9
|
UTSW |
17 |
46,811,774 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Cul9
|
UTSW |
17 |
46,811,782 (GRCm39) |
small insertion |
probably benign |
|
|
R0012:Cul9
|
UTSW |
17 |
46,849,436 (GRCm39) |
missense |
probably benign |
0.26 |
|
R0079:Cul9
|
UTSW |
17 |
46,848,589 (GRCm39) |
nonsense |
probably null |
|
|
R0143:Cul9
|
UTSW |
17 |
46,837,336 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R0390:Cul9
|
UTSW |
17 |
46,839,515 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0401:Cul9
|
UTSW |
17 |
46,852,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0529:Cul9
|
UTSW |
17 |
46,831,394 (GRCm39) |
splice site |
probably benign |
|
|
R0815:Cul9
|
UTSW |
17 |
46,848,748 (GRCm39) |
splice site |
probably null |
|
|
R0863:Cul9
|
UTSW |
17 |
46,848,748 (GRCm39) |
splice site |
probably null |
|
|
R0972:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1173:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1216:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1217:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1261:Cul9
|
UTSW |
17 |
46,836,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1278:Cul9
|
UTSW |
17 |
46,811,775 (GRCm39) |
small deletion |
probably benign |
|
|
R1281:Cul9
|
UTSW |
17 |
46,822,460 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1349:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1372:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1403:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1403:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1405:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1405:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1467:Cul9
|
UTSW |
17 |
46,836,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1467:Cul9
|
UTSW |
17 |
46,836,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1482:Cul9
|
UTSW |
17 |
46,819,473 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1491:Cul9
|
UTSW |
17 |
46,849,490 (GRCm39) |
nonsense |
probably null |
|
|
R1618:Cul9
|
UTSW |
17 |
46,836,818 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1641:Cul9
|
UTSW |
17 |
46,854,486 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1679:Cul9
|
UTSW |
17 |
46,832,082 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1771:Cul9
|
UTSW |
17 |
46,848,738 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1803:Cul9
|
UTSW |
17 |
46,814,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2020:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2046:Cul9
|
UTSW |
17 |
46,854,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2056:Cul9
|
UTSW |
17 |
46,854,298 (GRCm39) |
missense |
probably benign |
|
|
R2088:Cul9
|
UTSW |
17 |
46,837,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2415:Cul9
|
UTSW |
17 |
46,854,364 (GRCm39) |
missense |
probably benign |
|
|
R2925:Cul9
|
UTSW |
17 |
46,821,907 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2964:Cul9
|
UTSW |
17 |
46,813,154 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2965:Cul9
|
UTSW |
17 |
46,813,154 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3690:Cul9
|
UTSW |
17 |
46,814,957 (GRCm39) |
splice site |
probably null |
|
|
R3847:Cul9
|
UTSW |
17 |
46,836,061 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4437:Cul9
|
UTSW |
17 |
46,813,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4470:Cul9
|
UTSW |
17 |
46,849,262 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4540:Cul9
|
UTSW |
17 |
46,814,015 (GRCm39) |
missense |
probably null |
0.98 |
|
R4555:Cul9
|
UTSW |
17 |
46,812,755 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4604:Cul9
|
UTSW |
17 |
46,841,072 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4646:Cul9
|
UTSW |
17 |
46,849,943 (GRCm39) |
nonsense |
probably null |
|
|
R4799:Cul9
|
UTSW |
17 |
46,811,770 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R4822:Cul9
|
UTSW |
17 |
46,840,977 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4964:Cul9
|
UTSW |
17 |
46,849,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4965:Cul9
|
UTSW |
17 |
46,849,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5027:Cul9
|
UTSW |
17 |
46,811,708 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5185:Cul9
|
UTSW |
17 |
46,836,758 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5237:Cul9
|
UTSW |
17 |
46,854,393 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5278:Cul9
|
UTSW |
17 |
46,821,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5361:Cul9
|
UTSW |
17 |
46,811,775 (GRCm39) |
small deletion |
probably benign |
|
|
R5455:Cul9
|
UTSW |
17 |
46,821,772 (GRCm39) |
splice site |
probably null |
|
|
R5592:Cul9
|
UTSW |
17 |
46,831,517 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5597:Cul9
|
UTSW |
17 |
46,813,591 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R5613:Cul9
|
UTSW |
17 |
46,814,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6122:Cul9
|
UTSW |
17 |
46,832,854 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6135:Cul9
|
UTSW |
17 |
46,832,379 (GRCm39) |
missense |
probably benign |
|
|
R6352:Cul9
|
UTSW |
17 |
46,822,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6376:Cul9
|
UTSW |
17 |
46,819,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6868:Cul9
|
UTSW |
17 |
46,833,109 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6898:Cul9
|
UTSW |
17 |
46,821,952 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7090:Cul9
|
UTSW |
17 |
46,811,765 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7193:Cul9
|
UTSW |
17 |
46,849,423 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7221:Cul9
|
UTSW |
17 |
46,839,491 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7291:Cul9
|
UTSW |
17 |
46,851,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7320:Cul9
|
UTSW |
17 |
46,821,835 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7348:Cul9
|
UTSW |
17 |
46,821,919 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7463:Cul9
|
UTSW |
17 |
46,831,402 (GRCm39) |
splice site |
probably null |
|
|
R7480:Cul9
|
UTSW |
17 |
46,848,738 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7573:Cul9
|
UTSW |
17 |
46,830,836 (GRCm39) |
missense |
probably benign |
|
|
R7582:Cul9
|
UTSW |
17 |
46,821,905 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7605:Cul9
|
UTSW |
17 |
46,852,658 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7684:Cul9
|
UTSW |
17 |
46,820,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7830:Cul9
|
UTSW |
17 |
46,851,237 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7834:Cul9
|
UTSW |
17 |
46,836,630 (GRCm39) |
splice site |
probably null |
|
|
R8131:Cul9
|
UTSW |
17 |
46,822,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8192:Cul9
|
UTSW |
17 |
46,849,273 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8231:Cul9
|
UTSW |
17 |
46,831,427 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8248:Cul9
|
UTSW |
17 |
46,840,940 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8504:Cul9
|
UTSW |
17 |
46,814,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8550:Cul9
|
UTSW |
17 |
46,830,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8716:Cul9
|
UTSW |
17 |
46,838,840 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8769:Cul9
|
UTSW |
17 |
46,832,828 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8893:Cul9
|
UTSW |
17 |
46,811,775 (GRCm39) |
small deletion |
probably benign |
|
|
R8904:Cul9
|
UTSW |
17 |
46,831,427 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8936:Cul9
|
UTSW |
17 |
46,839,528 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8972:Cul9
|
UTSW |
17 |
46,854,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9003:Cul9
|
UTSW |
17 |
46,836,001 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9012:Cul9
|
UTSW |
17 |
46,854,447 (GRCm39) |
missense |
probably benign |
|
|
R9056:Cul9
|
UTSW |
17 |
46,854,696 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9071:Cul9
|
UTSW |
17 |
46,837,379 (GRCm39) |
missense |
probably benign |
|
|
R9162:Cul9
|
UTSW |
17 |
46,837,529 (GRCm39) |
missense |
probably benign |
0.32 |
|
R9476:Cul9
|
UTSW |
17 |
46,821,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9526:Cul9
|
UTSW |
17 |
46,841,026 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9563:Cul9
|
UTSW |
17 |
46,820,897 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9568:Cul9
|
UTSW |
17 |
46,831,044 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9610:Cul9
|
UTSW |
17 |
46,830,823 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9611:Cul9
|
UTSW |
17 |
46,830,823 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9705:Cul9
|
UTSW |
17 |
46,854,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9765:Cul9
|
UTSW |
17 |
46,850,224 (GRCm39) |
missense |
probably benign |
0.18 |
|
RF011:Cul9
|
UTSW |
17 |
46,811,774 (GRCm39) |
small insertion |
probably benign |
|
|
RF016:Cul9
|
UTSW |
17 |
46,811,789 (GRCm39) |
nonsense |
probably null |
|
|
RF026:Cul9
|
UTSW |
17 |
46,811,795 (GRCm39) |
nonsense |
probably null |
|
|
RF027:Cul9
|
UTSW |
17 |
46,811,774 (GRCm39) |
small insertion |
probably benign |
|
|
RF030:Cul9
|
UTSW |
17 |
46,811,795 (GRCm39) |
small insertion |
probably benign |
|
|
RF033:Cul9
|
UTSW |
17 |
46,811,780 (GRCm39) |
small insertion |
probably benign |
|
|
RF039:Cul9
|
UTSW |
17 |
46,811,780 (GRCm39) |
small insertion |
probably benign |
|
|
RF041:Cul9
|
UTSW |
17 |
46,811,780 (GRCm39) |
nonsense |
probably null |
|
|
RF042:Cul9
|
UTSW |
17 |
46,851,541 (GRCm39) |
frame shift |
probably null |
|
|
RF057:Cul9
|
UTSW |
17 |
46,811,789 (GRCm39) |
nonsense |
probably null |
|
|
Z1176:Cul9
|
UTSW |
17 |
46,831,511 (GRCm39) |
nonsense |
probably null |
|
|
Z1176:Cul9
|
UTSW |
17 |
46,831,502 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Cul9
|
UTSW |
17 |
46,848,723 (GRCm39) |
missense |
probably benign |
0.14 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAACAGAAGGTGCTTCAGACAC -3'
(R):5'- TGCAGAGTCCCTCAGTAGAG -3'
Sequencing Primer
(F):5'- TGCTTCAGACACTGGGAATC -3'
(R):5'- AGAGTCCCTCAGTAGAGACCCG -3'
|
| Posted On |
2018-04-05 |
Incidental Mutation