Incidental Mutation 'FR4737:Abcb4'
ID 511627
Institutional Source Beutler Lab
Gene Symbol Abcb4
Ensembl Gene ENSMUSG00000042476
Gene Name ATP-binding cassette, sub-family B (MDR/TAP), member 4
Synonyms Pgy-2, Mdr2, Pgy2, mdr-2
Accession Numbers

Ncbi RefSeq: NM_008830; MGI: 97569

Essential gene? Non essential (E-score: 0.000) question?
Stock # FR4737 ()
Quality Score 172.457
Status Not validated
Chromosome 5
Chromosomal Location 8893717-8959231 bp(+) (GRCm38)
Type of Mutation small deletion (1 aa in frame mutation)
DNA Base Change (assembly) GAAA to G at 8896597 bp (GRCm38)
Zygosity Homozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000142425 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000003717] [ENSMUST00000196067]
AlphaFold P21440
Predicted Effect probably benign
Transcript: ENSMUST00000003717
SMART Domains Protein: ENSMUSP00000003717
Gene: ENSMUSG00000042476

DomainStartEndE-ValueType
Pfam:ABC_membrane 54 342 2e-94 PFAM
AAA 418 610 3.97e-20 SMART
Pfam:ABC_membrane 708 982 6.3e-77 PFAM
AAA 1058 1246 4.49e-19 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000196067
SMART Domains Protein: ENSMUSP00000142425
Gene: ENSMUSG00000042476

DomainStartEndE-ValueType
Pfam:ABC_membrane 54 344 2.4e-95 PFAM
AAA 418 610 6.2e-22 SMART
Pfam:ABC_membrane 708 882 1.6e-37 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000197458
Coding Region Coverage
  • 1x: 99.8%
  • 3x: 99.6%
  • 10x: 98.8%
  • 20x: 97.0%
Validation Efficiency
MGI Phenotype Strain: 1857236
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for targeted mutations that inactivate the gene are unable to secrete phospholipids into bile, leading to progressive hepatic disease, with an end stage of 3 months. [provided by MGI curators]
Allele List at MGI

All alleles(3) : Targeted(3)

Other mutations in this stock
Total: 211 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700001K19Rik TCT TCTCCT 12: 110,668,448 (GRCm38) probably benign Het
2010300C02Rik T A 1: 37,625,035 (GRCm38) E594V probably benign Homo
2010300C02Rik C A 1: 37,625,036 (GRCm38) E594* probably null Homo
4930402H24Rik CC CCTGC 2: 130,770,752 (GRCm38) probably benign Het
4932415D10Rik TTCA T 10: 82,285,469 (GRCm38) probably benign Homo
4932438A13Rik TTATTAT TTATTATTATTATTACTATTAT 3: 37,050,754 (GRCm38) probably benign Het
A630001G21Rik CTGTT CT 1: 85,723,135 (GRCm38) probably benign Homo
Abcb11 C A 2: 69,243,518 (GRCm38) R1221L probably damaging Homo
Ahdc1 CT CTCGT 4: 133,062,759 (GRCm38) probably benign Homo
Alpk3 TCT TCTACT 7: 81,077,762 (GRCm38) probably benign Het
Amfr C G 8: 94,005,159 (GRCm38) G30R probably damaging Homo
Ankrd35 GC GCTAC 3: 96,683,849 (GRCm38) probably benign Homo
Anxa7 C T 14: 20,469,411 (GRCm38) G113E probably damaging Homo
Apc CAATAAAGC CAATAAAGCTAATAAAGC 18: 34,281,999 (GRCm38) probably benign Homo
Apol6 GTTT GTTTCTTT 15: 77,051,442 (GRCm38) probably null Homo
Arpc1b GGTGGC GGTGGCGTGGC 5: 145,126,787 (GRCm38) probably null Het
AY358078 C T 14: 51,805,698 (GRCm38) S281L unknown Homo
BC051142 CAG CAGAAG 17: 34,460,051 (GRCm38) probably benign Het
BC051142 GCA GCATCA 17: 34,460,068 (GRCm38) probably benign Het
Blm ACCTGC ACCTGCCTGC 7: 80,463,771 (GRCm38) probably null Het
Blm T TACCA 7: 80,463,774 (GRCm38) probably null Het
Blzf1 TTGT TT 1: 164,303,917 (GRCm38) probably null Homo
Btnl10 A AAGG 11: 58,923,931 (GRCm38) probably benign Homo
Cacna1a ACC ACCCCC 8: 84,638,726 (GRCm38) probably benign Homo
Cacna1a ACC ACCGCC 8: 84,638,720 (GRCm38) probably benign Het
Catsper2 TTC TTCTTTTACTTTGTC 2: 121,397,540 (GRCm38) probably benign Homo
Ccdc170 AC ACCCC 10: 4,561,029 (GRCm38) probably benign Het
Ccdc170 ACC ACCTCC 10: 4,561,023 (GRCm38) probably benign Het
Ccdc73 TAAG T 2: 104,991,840 (GRCm38) probably benign Homo
Ccnk TTCCCAC T 12: 108,202,507 (GRCm38) probably benign Het
Cdan1 A C 2: 120,724,971 (GRCm38) V763G probably damaging Het
Cdk6 A G 5: 3,344,211 (GRCm38) probably benign Het
Cdx1 GCTGCT GCTGCTTCTGCT 18: 61,019,878 (GRCm38) probably benign Het
Cdx1 TGCTGC TGCTGCCGCTGC 18: 61,019,874 (GRCm38) probably benign Het
Cfap46 CCTTCT CCTTCTTCT 7: 139,638,930 (GRCm38) probably benign Homo
Chd4 GC GCTCCCCC 6: 125,122,131 (GRCm38) probably benign Homo
Cluh CC CCTGAGGC 11: 74,669,533 (GRCm38) probably benign Het
Cluh GAGCCT GAGCCTAAGCCT 11: 74,669,524 (GRCm38) probably benign Het
Cluh CCCCGAGCC CCCCGAGCCCGAGCC 11: 74,669,514 (GRCm38) probably benign Het
Cluh AGCCTG AGCCTGCGCCTG 11: 74,669,519 (GRCm38) probably benign Het
Cntnap1 CCCAGC CCCAGCGCCAGC 11: 101,189,590 (GRCm38) probably benign Het
Cntnap1 GCCCCA GCCCCACCCCCA 11: 101,189,582 (GRCm38) probably benign Het
Cntnap1 GCCCCA GCCCCAACCCCA 11: 101,189,576 (GRCm38) probably benign Het
Cntnap1 AGCCCC AGCCCCCGCCCC 11: 101,189,569 (GRCm38) probably benign Het
Cul9 CTC CTCTTC 17: 46,500,858 (GRCm38) probably benign Het
Cul9 CTCTTC CTCTTCTTC 17: 46,500,846 (GRCm38) probably benign Het
Cyth2 C A 7: 45,813,042 (GRCm38) S102I possibly damaging Het
Dbr1 AGGAGG AGGAGGCGGAGG 9: 99,583,686 (GRCm38) probably benign Het
Dbr1 GGAGG GGAGGACGAGG 9: 99,583,699 (GRCm38) probably benign Het
Dhx8 GAGACC GAGACCCAGACC 11: 101,738,189 (GRCm38) probably benign Homo
Dhx8 CGAGAC CGAGACGGAGAC 11: 101,738,182 (GRCm38) probably benign Homo
Dhx8 GACCGA GACCGATACCGA 11: 101,738,179 (GRCm38) probably benign Homo
Dnah8 ACTGCCCCT ACT 17: 30,635,465 (GRCm38) probably benign Het
Dnah8 CCTCCCG C 17: 30,635,477 (GRCm38) probably benign Homo
Dnajb5 AGGTG A 4: 42,957,126 (GRCm38) probably null Het
Dusp10 G T 1: 184,037,056 (GRCm38) C73F probably damaging Homo
E4f1 CCG CCGACG 17: 24,455,192 (GRCm38) probably benign Homo
Eif3a TTA TTATTATA 19: 60,775,289 (GRCm38) probably benign Het
Fam81b TTC TTCGTC 13: 76,271,319 (GRCm38) probably benign Het
Fbxo22 G A 9: 55,209,382 (GRCm38) R56H probably damaging Het
Fcgr1 CTTCT C 3: 96,284,504 (GRCm38) probably null Het
Fcgr1 T C 3: 96,287,094 (GRCm38) D159G probably benign Homo
Fmn1 CCTCCT CCTCCTACTCCT 2: 113,525,778 (GRCm38) probably benign Het
Fmn1 CC CCCCCTGC 2: 113,525,781 (GRCm38) probably benign Het
Fmn1 CC CCTCCTTC 2: 113,525,784 (GRCm38) probably benign Het
G530012D18Rik GA GACAGAGATA 1: 85,577,178 (GRCm38) probably null Het
Gli3 G A 13: 15,644,357 (GRCm38) R248H probably damaging Het
Gm16503 G A 4: 147,541,253 (GRCm38) G68E unknown Het
Gm19345 GGATGGCAGGTG GG 7: 19,857,602 (GRCm38) probably null Het
Gm4340 AG AGCGG 10: 104,196,100 (GRCm38) probably benign Het
Gm4340 AGC AGCTGC 10: 104,196,097 (GRCm38) probably benign Het
Gm4340 GCA GCAACA 10: 104,196,077 (GRCm38) probably benign Het
Gm6309 C T 5: 146,168,183 (GRCm38) V307I probably benign Het
Gpatch11 AGGAA AGGAAGCGGAA 17: 78,842,180 (GRCm38) probably benign Het
Gpatch11 AAGAGG AAGAGGCAGAGG 17: 78,842,171 (GRCm38) probably benign Het
Hoxa10 T A 6: 52,234,186 (GRCm38) Q250L possibly damaging Homo
Hrh1 T C 6: 114,481,123 (GRCm38) I455T possibly damaging Het
Hspa1b GCGCC GC 17: 34,957,129 (GRCm38) probably benign Homo
Iba57 GAAA GAAAAA 11: 59,161,505 (GRCm38) probably null Homo
Igf1r TGGAGC TGGAGCTGGAGAGGGAGC 7: 68,226,181 (GRCm38) probably benign Het
Il17rd CGG CGGAGG 14: 27,082,680 (GRCm38) probably benign Het
Il2 AGGTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTG AGCTGCTGCTGCTGCTGCTGCTGCTG 3: 37,125,764 (GRCm38) probably benign Het
Il2 TGG TGGGGCTTGAAGCGG 3: 37,125,828 (GRCm38) probably benign Het
Kcng4 G T 8: 119,633,519 (GRCm38) Y39* probably null Homo
Klra2 G GAAATCCACAT 6: 131,221,852 (GRCm38) probably null Het
Kmt2b TCCTCC TCCTCCCCCTCC 7: 30,586,366 (GRCm38) probably benign Het
Kmt2b CCTCCT CCTCCTTCTCCT 7: 30,586,367 (GRCm38) probably benign Het
Kmt2b CCTCCT CCTCCTGCTCCT 7: 30,586,370 (GRCm38) probably benign Het
Kmt2b TCCTCC TCCTCCCCCTCC 7: 30,586,378 (GRCm38) probably benign Het
Krt10 TCC TCCTCCACC 11: 99,389,279 (GRCm38) probably benign Homo
Krt10 TCCTCC TCCTCCGCCTCC 11: 99,389,273 (GRCm38) probably benign Het
Krt10 TCCGCC TCCGCCGCC 11: 99,386,197 (GRCm38) probably benign Homo
Krtap28-10 TCCCACA TCCCACACCCACA 1: 83,042,123 (GRCm38) probably benign Homo
Krtap4-2 A ACAC 11: 99,635,013 (GRCm38) probably benign Het
Krtap9-3 AC ACAGGTGTCGC 11: 99,598,004 (GRCm38) probably benign Het
Las1l GAG GAGCAG X: 95,940,829 (GRCm38) probably benign Het
Las1l AGG AGGCGG X: 95,940,827 (GRCm38) probably benign Het
Las1l AGG AGGGGG X: 95,940,821 (GRCm38) probably benign Het
Lrit3 TGC TGCAGC 3: 129,788,806 (GRCm38) probably benign Het
Lrit3 GCT GCTTCT 3: 129,788,810 (GRCm38) probably benign Het
Lrit3 AC ACATTC 3: 129,803,913 (GRCm38) probably null Homo
Luzp1 A AGGTGGCCTCTTCAGT 4: 136,543,196 (GRCm38) probably benign Het
Mamld1 GCA GCAACA X: 71,118,839 (GRCm38) probably benign Het
Mamld1 AGC AGCCGC X: 71,118,835 (GRCm38) probably benign Het
Mapk8ip3 G A 17: 24,902,119 (GRCm38) probably null Homo
Mbd1 TGTCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC TATCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC 18: 74,273,573 (GRCm38) probably benign Het
Nat8f2 T A 6: 85,867,686 (GRCm38) L231F possibly damaging Homo
Nfxl1 CC CCGGGGAC 5: 72,559,121 (GRCm38) probably benign Het
Noc2l GGTAG GG 4: 156,241,501 (GRCm38) probably benign Homo
Noc2l CTG CTGTTG 4: 156,240,095 (GRCm38) probably benign Het
Noc2l GCT GCTTCT 4: 156,240,094 (GRCm38) probably benign Het
Nxpe5 C T 5: 138,229,934 (GRCm38) probably benign Het
Olfr1038-ps CAG CAGAG 2: 86,122,760 (GRCm38) probably null Homo
Olfr418 GGGCTGCTTGTGGCAAT G 1: 173,270,630 (GRCm38) probably null Het
Olfr568 CT CTAATTGCCTT 7: 102,877,233 (GRCm38) probably benign Homo
Olfr644 G C 7: 104,071,292 (GRCm38) probably benign Homo
Olfr890 A G 9: 38,143,188 (GRCm38) I13V probably benign Homo
Osmr C CTCA 15: 6,837,706 (GRCm38) probably null Homo
Patl2 C CTGA 2: 122,126,145 (GRCm38) probably benign Het
Patl2 GC GCTAC 2: 122,126,144 (GRCm38) probably null Het
Patl2 CTG CTGTTG 2: 122,126,136 (GRCm38) probably benign Het
Pdik1l GTTTTTGTTTT GTTTTTGTTTTTTTTTTGTTTT 4: 134,279,367 (GRCm38) probably null Homo
Pdik1l ACCACC ACCACCCCCACC 4: 134,279,506 (GRCm38) probably benign Het
Phc1 GCTG GCTGCTTCTG 6: 122,323,598 (GRCm38) probably benign Het
Piezo1 G A 8: 122,495,569 (GRCm38) R503W probably damaging Homo
Pitrm1 TTTTA T 13: 6,560,596 (GRCm38) probably benign Homo
Pkdrej TG TGGGAGCG 15: 85,819,680 (GRCm38) probably benign Homo
Pla2g4e AGGG A 2: 120,244,724 (GRCm38) probably benign Homo
Plekhs1 AC ACCTCCCCCGAGCC 19: 56,479,863 (GRCm38) probably benign Het
Pnmal1 CCTCATGATGCACCTGCTTCAACATC CCTCATGATGCACCTGCTTCAACATCTCATGATGCACCTGCTTCAACATC 7: 16,961,425 (GRCm38) probably benign Homo
Pnmal2 TGGA T 7: 16,946,006 (GRCm38) probably benign Het
Ppp1r3f C A X: 7,560,336 (GRCm38) G562V probably damaging Homo
Prr13 CTC CTCATC 15: 102,462,173 (GRCm38) probably benign Het
Prss41 CACA C 17: 23,844,097 (GRCm38) probably benign Het
Prtg GTAAC G 9: 72,857,081 (GRCm38) probably benign Het
Ptk2b C T 14: 66,173,849 (GRCm38) R411Q possibly damaging Homo
Ptms C CTTG 6: 124,914,461 (GRCm38) probably benign Homo
Ptms TTC TTCGTC 6: 124,914,459 (GRCm38) probably benign Homo
Ptms TCT TCTGCT 6: 124,914,457 (GRCm38) probably benign Homo
Ptpn23 G T 9: 110,387,633 (GRCm38) P1052T probably benign Homo
Rab3il1 C A 19: 10,033,751 (GRCm38) A264E probably damaging Homo
Rbm6 GCTGT G 9: 107,782,755 (GRCm38) probably null Homo
Rtbdn GGC GGCAGCTGC 8: 84,956,177 (GRCm38) probably benign Het
Rtbdn CGGC CGGCAGGGGC 8: 84,956,176 (GRCm38) probably benign Het
Rtbdn AGCG AGCGTCCGCG 8: 84,956,168 (GRCm38) probably benign Het
Rtbdn TAG TAGGGGCAG 8: 84,956,161 (GRCm38) probably benign Het
Sbp G GCTGACAACAAAGATC 17: 23,945,389 (GRCm38) probably benign Het
Sbp CAAAG CAAAGCTGCTGACAAAAAAG 17: 23,945,382 (GRCm38) probably benign Het
Setd1a GTGGTAGTG GTGGTAGTGTTGGTAGTG 7: 127,785,312 (GRCm38) probably benign Het
Sfswap GCCCACTC GCCCACTCATCCCACTC 5: 129,569,756 (GRCm38) probably benign Het
Six3 CGG CGGGGG 17: 85,621,368 (GRCm38) probably benign Het
Six3 CGG CGGGGG 17: 85,621,365 (GRCm38) probably benign Het
Six3 GGC GGCAGC 17: 85,621,363 (GRCm38) probably benign Het
Six3 CGG CGGGGG 17: 85,621,362 (GRCm38) probably benign Het
Six3 GCG GCGCCG 17: 85,621,358 (GRCm38) probably benign Het
Six3 GGC GGCAGC 17: 85,621,357 (GRCm38) probably benign Het
Slc12a1 ACC ACCTTTGGCCACAACTCC 2: 125,154,214 (GRCm38) probably benign Homo
Smarca2 CAGCAGCAGCAGCAGCAGCA CAGCAGCAGCAGCAGCAGCAGCAGCA 19: 26,630,999 (GRCm38) probably benign Homo
Spaca1 TCGCTC TCGCTCGCGCTC 4: 34,049,836 (GRCm38) probably benign Het
Spag1 TTC TTCGTC 15: 36,197,733 (GRCm38) probably benign Het
Spag17 AGG AGGCGG 3: 100,056,257 (GRCm38) probably benign Het
Srebf2 G T 15: 82,185,335 (GRCm38) A693S probably damaging Homo
Srpk2 T C 5: 23,545,196 (GRCm38) probably null Homo
Sry AACTGCT A Y: 2,663,195 (GRCm38) probably benign Het
Sry TGG TGGGGG Y: 2,662,838 (GRCm38) probably benign Homo
Sry GTG GTGTTG Y: 2,662,837 (GRCm38) probably benign Homo
St5 CACCACACTGGGGCAGCCCACACTGGGGCAG CCCCACACTGGGGCAG 7: 109,556,921 (GRCm38) probably benign Het
Stard9 C CTAAGGGACTAGTAGG 2: 120,696,085 (GRCm38) probably benign Het
Supt20 GCAGCA GCAGCAACAGCA 3: 54,727,657 (GRCm38) probably benign Het
Supt20 CAGCAG CAGCAGAAGCAG 3: 54,727,661 (GRCm38) probably benign Het
Supt20 CAGCAG CAGCAGGAGCAG 3: 54,727,658 (GRCm38) probably benign Het
Tcof1 GGGTA G 18: 60,828,650 (GRCm38) probably benign Homo
Tdpoz3 A C 3: 93,826,674 (GRCm38) N219H probably benign Het
Tesk1 C CCCCG 4: 43,447,004 (GRCm38) probably null Homo
Tob1 CACA CACAACA 11: 94,214,451 (GRCm38) probably benign Het
Tob1 GCA GCAACA 11: 94,214,464 (GRCm38) probably benign Het
Tob1 A AGCC 11: 94,214,478 (GRCm38) probably benign Het
Trav15-2-dv6-2 G GAAA 14: 53,649,757 (GRCm38) probably benign Homo
Trav15-2-dv6-2 AG AGAGG 14: 53,649,756 (GRCm38) probably benign Homo
Trim63 GAGT G 4: 134,327,725 (GRCm38) probably benign Het
Tsen2 G GAGA 6: 115,560,077 (GRCm38) probably benign Het
Ttf2 TC TCCCC 3: 100,963,160 (GRCm38) probably benign Homo
Tusc1 ACCGCC ACCGCCCCCGCC 4: 93,335,313 (GRCm38) probably benign Homo
Ubqlnl TGAG T 7: 104,149,835 (GRCm38) probably benign Homo
Ubtf TCC TCCACC 11: 102,306,950 (GRCm38) probably benign Het
Ubtf CCT CCTACT 11: 102,306,948 (GRCm38) probably null Het
Vps13b G T 15: 35,846,957 (GRCm38) A2629S probably damaging Homo
Wasf3 G T 5: 146,470,250 (GRCm38) R460L probably damaging Het
Zc3h13 TGCGAGATG TGCGAGATGAGCGAGATG 14: 75,323,599 (GRCm38) probably benign Homo
Zc3h13 ATGTGCGAG ATGTGCGAGGTGTGCGAG 14: 75,323,596 (GRCm38) probably benign Homo
Zfhx3 GCA GCAACAGCACCA 8: 108,956,103 (GRCm38) probably benign Het
Zfhx3 AGCA AGCAACAGACGCA 8: 108,956,102 (GRCm38) probably benign Het
Zfhx3 GCAACA GCAACAACAACAACA 8: 108,956,088 (GRCm38) probably benign Het
Zfp111 TCA TCAACA 7: 24,199,805 (GRCm38) probably benign Homo
Zfp112 CATGA CATGATGA 7: 24,125,407 (GRCm38) probably benign Homo
Zfp26 C A 9: 20,438,546 (GRCm38) A241S probably benign Homo
Zfp282 CGG CGGGGG 6: 47,904,799 (GRCm38) probably benign Het
Zfp282 CGG CGGGGG 6: 47,904,790 (GRCm38) probably benign Het
Zfp335 TC TCCCC 2: 164,907,484 (GRCm38) probably benign Het
Zfp335 TCC TCCGCC 2: 164,907,475 (GRCm38) probably benign Het
Zfp335 CTC CTCGTC 2: 164,907,474 (GRCm38) probably benign Het
Zfp462 CCACC CCACCTCAGCCACAGTCACC 4: 55,009,758 (GRCm38) probably benign Het
Zfp462 ACC ACCTCAGCCACAGTCGCC 4: 55,009,760 (GRCm38) probably benign Het
Zfp598 AC ACCACCGC 17: 24,680,791 (GRCm38) probably benign Het
Zfp598 ACCACC ACCACCGCCACC 17: 24,680,782 (GRCm38) probably benign Het
Zfp598 ACCACC ACCACCCCCACC 17: 24,680,776 (GRCm38) probably benign Het
Zfp831 TC TCCGC 2: 174,645,483 (GRCm38) probably benign Het
Zfp831 CTC CTCATC 2: 174,645,476 (GRCm38) probably benign Het
Zfp831 TCC TCCCCC 2: 174,645,471 (GRCm38) probably benign Het
Zfp93 CAGGCATAG CAG 7: 24,275,389 (GRCm38) probably benign Homo
Zscan10 TGACG TG 17: 23,609,445 (GRCm38) probably benign Homo
Other mutations in Abcb4
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00570:Abcb4 APN 5 8,950,073 (GRCm38) missense probably benign 0.02
IGL00663:Abcb4 APN 5 8,927,916 (GRCm38) missense probably damaging 1.00
IGL00671:Abcb4 APN 5 8,930,745 (GRCm38) nonsense probably null
IGL00822:Abcb4 APN 5 8,950,046 (GRCm38) missense probably benign
IGL01080:Abcb4 APN 5 8,934,258 (GRCm38) missense probably damaging 1.00
IGL01152:Abcb4 APN 5 8,950,678 (GRCm38) missense probably benign 0.19
IGL01329:Abcb4 APN 5 8,894,166 (GRCm38) critical splice donor site probably null
IGL01483:Abcb4 APN 5 8,927,871 (GRCm38) missense probably damaging 0.99
IGL01594:Abcb4 APN 5 8,946,071 (GRCm38) splice site probably null
IGL01785:Abcb4 APN 5 8,915,058 (GRCm38) nonsense probably null
IGL01968:Abcb4 APN 5 8,927,913 (GRCm38) missense probably benign 0.33
IGL02579:Abcb4 APN 5 8,955,537 (GRCm38) missense probably damaging 1.00
IGL02654:Abcb4 APN 5 8,927,826 (GRCm38) missense possibly damaging 0.80
IGL02658:Abcb4 APN 5 8,934,240 (GRCm38) missense probably benign
IGL03229:Abcb4 APN 5 8,940,936 (GRCm38) missense probably damaging 0.97
IGL03335:Abcb4 APN 5 8,935,258 (GRCm38) missense probably benign 0.00
P0014:Abcb4 UTSW 5 8,950,083 (GRCm38) missense probably benign 0.01
R0102:Abcb4 UTSW 5 8,909,194 (GRCm38) missense probably damaging 0.99
R0102:Abcb4 UTSW 5 8,909,194 (GRCm38) missense probably damaging 0.99
R0309:Abcb4 UTSW 5 8,939,835 (GRCm38) missense probably damaging 1.00
R0311:Abcb4 UTSW 5 8,934,243 (GRCm38) missense probably benign
R0420:Abcb4 UTSW 5 8,941,050 (GRCm38) missense probably benign 0.03
R0449:Abcb4 UTSW 5 8,939,885 (GRCm38) nonsense probably null
R0609:Abcb4 UTSW 5 8,947,376 (GRCm38) missense probably damaging 0.96
R1459:Abcb4 UTSW 5 8,918,662 (GRCm38) missense possibly damaging 0.61
R1470:Abcb4 UTSW 5 8,940,968 (GRCm38) missense probably damaging 0.98
R1470:Abcb4 UTSW 5 8,940,968 (GRCm38) missense probably damaging 0.98
R1812:Abcb4 UTSW 5 8,928,578 (GRCm38) critical splice donor site probably null
R1944:Abcb4 UTSW 5 8,930,796 (GRCm38) missense probably damaging 1.00
R2002:Abcb4 UTSW 5 8,905,989 (GRCm38) missense probably benign 0.01
R2256:Abcb4 UTSW 5 8,958,431 (GRCm38) missense probably damaging 1.00
R3116:Abcb4 UTSW 5 8,896,610 (GRCm38) missense possibly damaging 0.86
R4112:Abcb4 UTSW 5 8,936,783 (GRCm38) critical splice acceptor site probably null
R4354:Abcb4 UTSW 5 8,918,771 (GRCm38) missense probably benign 0.44
R4512:Abcb4 UTSW 5 8,928,573 (GRCm38) missense probably damaging 1.00
R4588:Abcb4 UTSW 5 8,947,328 (GRCm38) missense probably benign 0.01
R4628:Abcb4 UTSW 5 8,907,399 (GRCm38) missense probably benign 0.08
R4708:Abcb4 UTSW 5 8,915,125 (GRCm38) missense possibly damaging 0.90
R4714:Abcb4 UTSW 5 8,930,906 (GRCm38) splice site probably null
R4754:Abcb4 UTSW 5 8,910,717 (GRCm38) missense probably damaging 1.00
R4846:Abcb4 UTSW 5 8,935,180 (GRCm38) missense probably benign
R4896:Abcb4 UTSW 5 8,907,267 (GRCm38) missense possibly damaging 0.81
R4944:Abcb4 UTSW 5 8,934,327 (GRCm38) critical splice donor site probably null
R4994:Abcb4 UTSW 5 8,928,524 (GRCm38) missense probably damaging 1.00
R5022:Abcb4 UTSW 5 8,909,054 (GRCm38) splice site probably null
R5537:Abcb4 UTSW 5 8,955,485 (GRCm38) missense probably damaging 0.98
R5754:Abcb4 UTSW 5 8,934,320 (GRCm38) missense probably benign
R5833:Abcb4 UTSW 5 8,958,314 (GRCm38) missense probably damaging 1.00
R5934:Abcb4 UTSW 5 8,930,806 (GRCm38) missense probably benign 0.18
R6006:Abcb4 UTSW 5 8,946,026 (GRCm38) missense probably damaging 0.99
R6146:Abcb4 UTSW 5 8,896,587 (GRCm38) missense probably benign 0.05
R6183:Abcb4 UTSW 5 8,918,718 (GRCm38) missense probably benign
R6260:Abcb4 UTSW 5 8,934,219 (GRCm38) nonsense probably null
R6561:Abcb4 UTSW 5 8,927,825 (GRCm38) missense probably benign 0.14
R7016:Abcb4 UTSW 5 8,936,843 (GRCm38) missense probably benign 0.35
R7081:Abcb4 UTSW 5 8,934,263 (GRCm38) missense probably benign
R7326:Abcb4 UTSW 5 8,934,226 (GRCm38) missense probably benign 0.00
R7375:Abcb4 UTSW 5 8,918,671 (GRCm38) missense probably benign
R7787:Abcb4 UTSW 5 8,909,220 (GRCm38) missense probably damaging 1.00
R7836:Abcb4 UTSW 5 8,934,203 (GRCm38) missense probably benign
R8128:Abcb4 UTSW 5 8,958,395 (GRCm38) missense probably damaging 1.00
R8350:Abcb4 UTSW 5 8,928,578 (GRCm38) critical splice donor site probably null
R8438:Abcb4 UTSW 5 8,946,120 (GRCm38) critical splice donor site probably null
R8447:Abcb4 UTSW 5 8,907,278 (GRCm38) missense probably damaging 0.97
R8710:Abcb4 UTSW 5 8,955,495 (GRCm38) missense probably damaging 1.00
R8777:Abcb4 UTSW 5 8,939,894 (GRCm38) missense probably benign 0.01
R8777-TAIL:Abcb4 UTSW 5 8,939,894 (GRCm38) missense probably benign 0.01
R8837:Abcb4 UTSW 5 8,936,873 (GRCm38) missense probably damaging 0.99
R8987:Abcb4 UTSW 5 8,927,931 (GRCm38) missense probably benign 0.02
R9098:Abcb4 UTSW 5 8,958,441 (GRCm38) missense probably damaging 1.00
R9167:Abcb4 UTSW 5 8,936,849 (GRCm38) nonsense probably null
R9210:Abcb4 UTSW 5 8,955,591 (GRCm38) missense probably damaging 1.00
R9212:Abcb4 UTSW 5 8,955,591 (GRCm38) missense probably damaging 1.00
R9218:Abcb4 UTSW 5 8,927,960 (GRCm38) missense probably benign 0.20
R9242:Abcb4 UTSW 5 8,899,677 (GRCm38) missense probably damaging 1.00
R9376:Abcb4 UTSW 5 8,958,988 (GRCm38) missense probably damaging 1.00
R9476:Abcb4 UTSW 5 8,927,790 (GRCm38) missense probably damaging 1.00
RF015:Abcb4 UTSW 5 8,896,594 (GRCm38) frame shift probably null
RF047:Abcb4 UTSW 5 8,896,595 (GRCm38) frame shift probably null
Z1176:Abcb4 UTSW 5 8,959,005 (GRCm38) missense probably damaging 1.00
Z1177:Abcb4 UTSW 5 8,939,906 (GRCm38) nonsense probably null
Predicted Primers PCR Primer
(F):5'- CCAGATGTCCTTGTAGTACCTTGG -3'
(R):5'- GCAAACCATAGGCACAAGTG -3'

Sequencing Primer
(F):5'- AGTACCTTGGACAGTTACCTTTG -3'
(R):5'- TGCAACAGAGGCAATCCAGTG -3'
Posted On 2018-04-05