Mutagenetix > Incidental Mutation

Incidental Mutation 'FR4976:Kmt2c'

511839

Institutional Source

Beutler Lab

Gene Symbol

Kmt2c

Ensembl Gene

ENSMUSG00000038056

Gene Name

lysine (K)-specific methyltransferase 2C

Synonyms

Mll3, E330008K23Rik, HALR

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

FR4976 ()

Quality Score

214.458

Status

Not validated

Chromosome

Chromosomal Location

25271798-25498783 bp(-) (GRCm38)

Type of Mutation

small insertion (2 aa in frame mutation)

DNA Base Change (assembly)

TGCTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCT to TGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCT at 25315763 bp (GRCm38)

Zygosity

Homozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000134442 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000045291] [ENSMUST00000173073]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000045291

SMART Domains

Protein: ENSMUSP00000043874
Gene: ENSMUSG00000038056

Domain	Start	End	E-Value	Type
low complexity region	9	32	N/A	INTRINSIC
AT_hook	34	46	9.68e-1	SMART
low complexity region	73	87	N/A	INTRINSIC
PHD	283	330	2.56e-2	SMART
C1	329	384	5.45e-1	SMART
PHD	342	388	4.19e-7	SMART
RING	343	387	1.45e-1	SMART
PHD	389	435	4.77e-11	SMART
RING	390	434	1.46e0	SMART
PHD	465	517	8.25e-6	SMART
low complexity region	776	789	N/A	INTRINSIC
AT_hook	898	910	1.41e2	SMART
PHD	953	1002	2.89e-10	SMART
RING	954	1001	4.74e0	SMART
C1	994	1045	8.38e-2	SMART
PHD	1003	1049	1.05e-12	SMART
PHD	1080	1131	2.08e-2	SMART
low complexity region	1189	1201	N/A	INTRINSIC
low complexity region	1337	1348	N/A	INTRINSIC
low complexity region	1394	1406	N/A	INTRINSIC
low complexity region	1431	1442	N/A	INTRINSIC
low complexity region	1520	1539	N/A	INTRINSIC
low complexity region	1557	1570	N/A	INTRINSIC
HMG	1639	1703	2.64e-3	SMART
low complexity region	1708	1724	N/A	INTRINSIC
coiled coil region	1745	1789	N/A	INTRINSIC
low complexity region	1847	1860	N/A	INTRINSIC
low complexity region	1864	1891	N/A	INTRINSIC
internal_repeat_3	1893	2084	1.27e-14	PROSPERO
internal_repeat_3	2123	2306	1.27e-14	PROSPERO
low complexity region	2336	2348	N/A	INTRINSIC
low complexity region	2375	2394	N/A	INTRINSIC
low complexity region	2427	2440	N/A	INTRINSIC
low complexity region	2516	2527	N/A	INTRINSIC
low complexity region	2696	2720	N/A	INTRINSIC
low complexity region	2723	2742	N/A	INTRINSIC
low complexity region	2930	2943	N/A	INTRINSIC
coiled coil region	3048	3075	N/A	INTRINSIC
low complexity region	3156	3165	N/A	INTRINSIC
low complexity region	3173	3195	N/A	INTRINSIC
coiled coil region	3226	3270	N/A	INTRINSIC
low complexity region	3277	3290	N/A	INTRINSIC
coiled coil region	3389	3427	N/A	INTRINSIC
low complexity region	3460	3486	N/A	INTRINSIC
low complexity region	3597	3611	N/A	INTRINSIC
low complexity region	3649	3667	N/A	INTRINSIC
low complexity region	3769	3783	N/A	INTRINSIC
low complexity region	3822	3827	N/A	INTRINSIC
low complexity region	3860	3869	N/A	INTRINSIC
low complexity region	3887	3904	N/A	INTRINSIC
low complexity region	3994	4009	N/A	INTRINSIC
low complexity region	4015	4038	N/A	INTRINSIC
low complexity region	4293	4309	N/A	INTRINSIC
low complexity region	4412	4419	N/A	INTRINSIC
PHD	4454	4500	2.94e-2	SMART
RING	4455	4499	8.1e0	SMART
FYRN	4554	4597	1.18e-21	SMART
FYRC	4603	4690	4.54e-32	SMART
SET	4764	4886	3.17e-34	SMART
PostSET	4888	4904	1.82e-6	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000173073

SMART Domains

Protein: ENSMUSP00000134442
Gene: ENSMUSG00000038056

Domain	Start	End	E-Value	Type
low complexity region	9	32	N/A	INTRINSIC
AT_hook	34	46	9.68e-1	SMART
low complexity region	73	87	N/A	INTRINSIC
PHD	283	330	2.56e-2	SMART
C1	329	384	5.45e-1	SMART
PHD	342	388	4.19e-7	SMART
RING	343	387	1.45e-1	SMART
PHD	389	435	4.77e-11	SMART
RING	390	434	1.46e0	SMART
PHD	465	517	8.25e-6	SMART
low complexity region	776	789	N/A	INTRINSIC
AT_hook	858	870	1.41e2	SMART
PHD	913	962	2.89e-10	SMART
RING	914	961	4.74e0	SMART
C1	954	1005	8.38e-2	SMART
PHD	963	1009	1.05e-12	SMART
PHD	1040	1091	2.08e-2	SMART
low complexity region	1149	1161	N/A	INTRINSIC
low complexity region	1297	1308	N/A	INTRINSIC
low complexity region	1354	1366	N/A	INTRINSIC
low complexity region	1445	1464	N/A	INTRINSIC
low complexity region	1482	1495	N/A	INTRINSIC
HMG	1564	1628	2.64e-3	SMART
low complexity region	1633	1649	N/A	INTRINSIC
coiled coil region	1670	1714	N/A	INTRINSIC

Coding Region Coverage

1x: 99.8%
3x: 99.6%
10x: 98.7%
20x: 96.9%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele display partial embryonic lethality, delayed eyelid opening, postnatal growth retardation, impaired fertility in both sexes, and decreased proliferation of cultured mouse embryonic fibroblasts. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 222 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700001K19Rik	TTC	TTCATC	12: 110,668,447 (GRCm38)		probably benign	Het
1700001K19Rik	TTC	TTCGTC	12: 110,668,450 (GRCm38)		probably benign	Het
2010300C02Rik	T	A	1: 37,625,035 (GRCm38)	E594V	probably benign	Homo
2010300C02Rik	C	A	1: 37,625,036 (GRCm38)	E594*	probably null	Homo
2010300C02Rik	A	G	1: 37,625,102 (GRCm38)	S47P	probably damaging	Homo
4930402H24Rik	C	CTCG	2: 130,770,753 (GRCm38)		probably benign	Het
4930402H24Rik	TCC	TCCACC	2: 130,770,742 (GRCm38)		probably benign	Het
4930402H24Rik	TCC	TCCCCC	2: 130,770,739 (GRCm38)		probably benign	Het
Abt1	TTCTTGCT	TT	13: 23,423,711 (GRCm38)		probably benign	Het
AI837181	GGC	GGCCGC	19: 5,425,229 (GRCm38)		probably benign	Het
Akap12	AAA	AAACAA	10: 4,353,837 (GRCm38)		probably benign	Het
Alg1	GCTCACTCAC	GCTCAC	16: 5,244,561 (GRCm38)		probably null	Homo
Alg9	G	GCGA	9: 50,775,431 (GRCm38)		probably benign	Het
Amfr	GCC	GCCGGCGCGAGCTCC	8: 94,012,292 (GRCm38)		probably benign	Het
Anapc2	TGGCGGTGGCGGCGGCGGCGGCGGCGGCGG	TGGCGGCGGCGGCGGCGG	2: 25,272,532 (GRCm38)		probably benign	Het
Anxa7	C	T	14: 20,469,411 (GRCm38)	G113E	probably damaging	Homo
Apc	CCAATAAAG	CCAATAAAGTCAATAAAG	18: 34,281,998 (GRCm38)		probably benign	Het
Apc	AATAAAGC	AATAAAGCCTATAAAGC	18: 34,282,000 (GRCm38)		probably benign	Het
Apc	AAGC	AAGCCAATATAGC	18: 34,282,004 (GRCm38)		probably null	Het
Atad3a	C	A	4: 155,753,939 (GRCm38)	R207L	probably damaging	Homo
BC051142	AGC	AGCGGC	17: 34,460,061 (GRCm38)		probably benign	Het
BC051142	AGC	AGCGGC	17: 34,460,058 (GRCm38)		probably benign	Het
Blm	ACCT	ACCTCCCT	7: 80,463,767 (GRCm38)		probably benign	Homo
Blm	TCCTCCTCCTCCTCCTCCTCCTCC	TCCTCCTCCTCCACCTCCTCCTCCTCCTCCTCCTCC	7: 80,512,907 (GRCm38)		probably benign	Het
Bmp5	GAGGAGT	G	9: 75,776,375 (GRCm38)		probably benign	Homo
Bpifa6	A	T	2: 153,986,376 (GRCm38)	Q134L	probably benign	Homo
Bpifa6	A	T	2: 153,986,398 (GRCm38)	R141S	probably benign	Homo
Btnl10	AGA	AGAGGA	11: 58,923,929 (GRCm38)		probably benign	Homo
Cacna1a	ACC	ACCGCC	8: 84,638,717 (GRCm38)		probably benign	Het
Cacna1a	ACC	ACCTCC	8: 84,638,726 (GRCm38)		probably benign	Het
Calhm1	TGGCTGTGGCTG	TGGCTGTGGCTGCGGCTGTGGCTG	19: 47,141,262 (GRCm38)		probably benign	Het
Catsper2	ATCGTCGTCGTC	ATCGTCGTCGTCGTC	2: 121,397,795 (GRCm38)		probably benign	Het
Catsper2	CAT	CATTAT	2: 121,397,782 (GRCm38)		probably benign	Het
Catsper2	TGTC	TGTCGTC	2: 121,397,779 (GRCm38)		probably benign	Homo
Catsper2	C	CTTTTACTTTTTT	2: 121,397,542 (GRCm38)		probably benign	Homo
Ccdc170	ACCGCC	ACCGCCGCC	10: 4,561,008 (GRCm38)		probably benign	Het
Ccdc170	ACC	ACCGCC	10: 4,561,023 (GRCm38)		probably benign	Het
Ccdc170	AC	ACCTC	10: 4,561,029 (GRCm38)		probably benign	Het
Ccnk	TTCCCAC	T	12: 108,202,507 (GRCm38)		probably benign	Het
Cdx1	GGGCTGC	GGGCTGCGGCTGC	18: 61,019,867 (GRCm38)		probably benign	Het
Cdx1	GCTGCT	GCTGCTTCTGCT	18: 61,019,869 (GRCm38)		probably benign	Het
Cep112	G	GCTCT	11: 108,425,352 (GRCm38)		probably benign	Het
Cep89	GACT	G	7: 35,409,641 (GRCm38)		probably benign	Het
Cfap46	CCTTCT	CCTTCTTCT	7: 139,638,930 (GRCm38)		probably benign	Homo
Chd4	GC	GCTCCCTC	6: 125,122,131 (GRCm38)		probably benign	Homo
Cluh	GCCTGA	GCCTGAACCTGA	11: 74,669,520 (GRCm38)		probably benign	Het
Cnpy3	CCT	CCTACT	17: 46,736,747 (GRCm38)		probably null	Het
Cntnap1	A	ACCCCCC	11: 101,189,569 (GRCm38)		probably benign	Het
Cntnap1	CCCAGC	CCCAGCACCAGC	11: 101,189,572 (GRCm38)		probably benign	Het
Cntnap1	CCAGCC	CCAGCCTCAGCC	11: 101,189,585 (GRCm38)		probably benign	Het
Cntnap1	GCCCCA	GCCCCACCCCCA	11: 101,189,588 (GRCm38)		probably benign	Het
Col4a3	CGTTTTTTTTTTTTTTTT	C	1: 82,718,906 (GRCm38)		probably null	Het
Cpne1	AGA	AGAGAGA	2: 156,072,025 (GRCm38)		probably null	Homo
Ctsm	AGTG	AGTGGGTG	13: 61,537,836 (GRCm38)		probably null	Homo
Cttnbp2	GCTGCT	GCTGCTCCTGCT	6: 18,367,461 (GRCm38)		probably benign	Het
Cttnbp2	GCTGCT	GCTGCTTCTGCT	6: 18,367,467 (GRCm38)		probably benign	Het
Cul9	TCC	TCCCCC	17: 46,500,856 (GRCm38)		probably benign	Het
Cul9	CTTC	CTTCTTC	17: 46,500,848 (GRCm38)		probably benign	Het
Cul9	TCC	TCCCCC	17: 46,500,853 (GRCm38)		probably benign	Het
Cul9	TCC	TCCGCC	17: 46,500,850 (GRCm38)		probably benign	Het
Cybrd1	GAAT	G	2: 71,138,511 (GRCm38)		probably benign	Homo
Dbr1	AGGAGG	AGGAGGCGGAGG	9: 99,583,689 (GRCm38)		probably benign	Het
Dbr1	AGGAGG	AGGAGGCGGAGG	9: 99,583,692 (GRCm38)		probably benign	Het
Dbr1	AGG	AGGAGGCGG	9: 99,583,701 (GRCm38)		probably benign	Het
Dbr1	GG	GGAGGAAG	9: 99,583,702 (GRCm38)		probably benign	Het
Dcaf8	C	T	1: 172,172,856 (GRCm38)	H194Y	probably damaging	Homo
Dnajc19	AC	ACGC	3: 34,057,994 (GRCm38)		probably null	Het
Dthd1	GAC	GACTAC	5: 62,843,024 (GRCm38)		probably benign	Homo
Dusp10	G	T	1: 184,037,056 (GRCm38)	C73F	probably damaging	Homo
Eif3a	A	ATTTTT	19: 60,775,291 (GRCm38)		probably benign	Homo
Ermn	CTT	CTTGTT	2: 58,048,080 (GRCm38)		probably benign	Het
Ermn	TC	TCTAC	2: 58,048,088 (GRCm38)		probably benign	Het
Fam45a	ACTC	ACTCCTC	19: 60,814,618 (GRCm38)		probably benign	Homo
Fam45a	T	TTCA	19: 60,814,622 (GRCm38)		probably benign	Homo
Fbxo38	TGCAGC	TGC	18: 62,515,347 (GRCm38)		probably benign	Het
Frem3	CT	CTTGT	8: 80,615,241 (GRCm38)		probably benign	Homo
Fsip2	TTTTT	TTTTTGTTTT	2: 82,984,362 (GRCm38)		probably benign	Het
Fsip2	TT	TTTTTCT	2: 82,984,365 (GRCm38)		probably benign	Het
Gabre	T	TGAGGCC	X: 72,270,422 (GRCm38)		probably benign	Homo
Gabre	AGGCT	AGGCTGCGGCT	X: 72,270,418 (GRCm38)		probably benign	Homo
Gm10800	A	AC	2: 98,667,033 (GRCm38)		probably null	Homo
Gm14393	T	G	2: 175,061,820 (GRCm38)	N98T	probably benign	Het
Gm16503	G	A	4: 147,541,253 (GRCm38)	G68E	unknown	Het
Gm28040	TG	TGGCACCTTTCGAG	1: 133,327,323 (GRCm38)		probably benign	Homo
Gm4340	AGC	AGCCGC	10: 104,196,079 (GRCm38)		probably benign	Het
Gm6309	C	T	5: 146,168,183 (GRCm38)	V307I	probably benign	Het
Gm7534	TG	TGCCG	4: 134,202,630 (GRCm38)		probably benign	Homo
Golga5	G	A	12: 102,475,660 (GRCm38)		probably null	Homo
Gpatch11	GAAGAG	GAAGAGCAAGAG	17: 78,842,170 (GRCm38)		probably benign	Het
Gpatch11	AAGAGG	AAGAGGCAGAGG	17: 78,842,171 (GRCm38)		probably benign	Het
Gpatch11	AGAGGA	AGAGGATGAGGA	17: 78,842,172 (GRCm38)		probably benign	Het
Gpatch11	GAGGAA	GAGGAATAGGAA	17: 78,842,173 (GRCm38)		probably null	Het
Gpatch11	AGGAA	AGGAAGTGGAA	17: 78,842,180 (GRCm38)		probably benign	Het
H2-K1	GTTT	G	17: 33,997,042 (GRCm38)		probably benign	Homo
Hcn1	GCAGC	GCAGCGACAGC	13: 117,975,808 (GRCm38)		probably benign	Homo
Hoxa10	T	A	6: 52,234,186 (GRCm38)	Q250L	possibly damaging	Homo
Igf1r	C	CTGGAGATGGAGA	7: 68,226,186 (GRCm38)		probably benign	Het
Igf1r	TGGAGC	TGGAGCTGGAGAGGGAGC	7: 68,226,181 (GRCm38)		probably benign	Het
Il17rd	CGG	CGGTGG	14: 27,082,677 (GRCm38)		probably benign	Het
Il2	GG	GGGGCTTGAAGTAG	3: 37,125,829 (GRCm38)		probably benign	Het
Ipo9	TCC	TCCCCC	1: 135,386,281 (GRCm38)		probably benign	Het
Iqcc	T	TGTCAGCCTCCTTGTACCC	4: 129,616,676 (GRCm38)		probably benign	Het
Isg20l2	AAG	AAGTAG	3: 87,931,715 (GRCm38)		probably null	Het
Kcng4	G	T	8: 119,633,519 (GRCm38)	Y39*	probably null	Homo
Kmt2b	CCTCCT	CCTCCTGCTCCT	7: 30,586,373 (GRCm38)		probably benign	Het
Kmt2b	TCCTCC	TCCTCCACCTCC	7: 30,586,366 (GRCm38)		probably benign	Het
Kmt2b	CCTCCT	CCTCCTACTCCT	7: 30,586,364 (GRCm38)		probably null	Het
Kmt2b	CTCCTC	CTCCTCGTCCTC	7: 30,586,362 (GRCm38)		probably benign	Het
Kmt2b	TCCTCC	TCCTCCCCCTCC	7: 30,586,360 (GRCm38)		probably benign	Het
Krtap9-3	AC	ACAGGTGCCTC	11: 99,598,004 (GRCm38)		probably benign	Homo
Las1l	AGG	AGGGGG	X: 95,940,827 (GRCm38)		probably benign	Het
Las1l	GA	GAGAA	X: 95,940,832 (GRCm38)		probably benign	Het
Las1l	A	AGGC	X: 95,940,833 (GRCm38)		probably benign	Het
Lce1m	TGCCAC	TGCCACTGCTGCAGCCAC	3: 93,018,148 (GRCm38)		probably benign	Het
Leo1	GGTACCATGCAG	GG	9: 75,450,572 (GRCm38)		probably benign	Het
Lrit3	CATA	CATAAATA	3: 129,803,910 (GRCm38)		probably benign	Homo
Lrmp	CACATTG	CACATTGAGGACATTG	6: 145,173,785 (GRCm38)		probably benign	Homo
Mamld1	GCA	GCAACA	X: 71,118,818 (GRCm38)		probably benign	Het
Mamld1	GCAACA	GCAACAACA	X: 71,118,812 (GRCm38)		probably benign	Het
Mast4	GGACAAGCTGTGAGTTGGGGAACCCGGGAG	GG	13: 102,739,247 (GRCm38)		probably null	Homo
Mast4	TGG	TGGGGGCGG	13: 102,736,312 (GRCm38)		probably benign	Het
Med12l	GCA	GCACCA	3: 59,275,977 (GRCm38)		probably benign	Het
Mn1	CAG	CAGAAG	5: 111,419,702 (GRCm38)		probably benign	Het
Morf4l2	T	C	X: 136,733,622 (GRCm38)	K286E	probably benign	Het
Msantd4	A	T	9: 4,384,937 (GRCm38)	I221F	possibly damaging	Homo
Mup21	TT	TTTTTATATACT	4: 62,149,350 (GRCm38)		probably benign	Het
Nacad	A	ACCAGGG	11: 6,599,749 (GRCm38)		probably benign	Het
Nacad	TCAGGG	TCAGGGACAGGG	11: 6,599,756 (GRCm38)		probably benign	Het
Nacad	C	CAGGGTA	11: 6,599,763 (GRCm38)		probably benign	Het
Nars	CCACTCAC	CCAC	18: 64,510,445 (GRCm38)		probably benign	Homo
Ndufc2	C	T	7: 97,400,274 (GRCm38)	P29L	probably damaging	Het
Nkx2-6	C	T	14: 69,175,229 (GRCm38)	T282M	probably damaging	Homo
Noc2l	CTG	CTGGTG	4: 156,240,098 (GRCm38)		probably benign	Het
Noc2l	AGGC	AGGCGGC	4: 156,240,092 (GRCm38)		probably benign	Homo
Nolc1	CAG	CAGAAGCAGAAG	19: 46,081,356 (GRCm38)		probably benign	Het
Nolc1	AGC	AGCAGCAGCGGC	19: 46,081,375 (GRCm38)		probably benign	Het
Olfr313	T	A	11: 58,817,440 (GRCm38)	V144D	possibly damaging	Homo
Olfr418	GGGCTGCTTGTGGCAAT	G	1: 173,270,630 (GRCm38)		probably null	Het
Olfr547	A	AAACCG	7: 102,535,681 (GRCm38)		probably null	Homo
Olfr585	T	TTAC	7: 103,098,309 (GRCm38)		probably benign	Homo
Olfr624	AG	AGAGG	7: 103,670,966 (GRCm38)		probably benign	Homo
Patl2	C	CTGA	2: 122,126,145 (GRCm38)		probably benign	Het
Patl2	CTG	CTGGTG	2: 122,126,139 (GRCm38)		probably benign	Het
Patl2	GCT	GCTTCT	2: 122,126,141 (GRCm38)		probably benign	Het
Patl2	GC	GCTTC	2: 122,126,144 (GRCm38)		probably benign	Het
Pdik1l	ACCACC	ACCACCCCCACC	4: 134,279,506 (GRCm38)		probably benign	Homo
Phc1	TG	TGCTGCGG	6: 122,323,600 (GRCm38)		probably benign	Het
Phf3	ACTGCCGCTCCCGCTCC	AC	1: 30,805,023 (GRCm38)		probably benign	Het
Pick1	TTC	TTCTC	15: 79,255,946 (GRCm38)		probably null	Homo
Piezo1	G	A	8: 122,495,569 (GRCm38)	R503W	probably damaging	Homo
Pik3ap1	AG	AGGGG	19: 41,281,945 (GRCm38)		probably benign	Homo
Pik3c2g	AGAGG	AGAGGGAGG	6: 139,635,654 (GRCm38)		probably null	Homo
Pitrm1	TTTTA	T	13: 6,560,596 (GRCm38)		probably benign	Homo
Pogz	GTAAT	G	3: 94,874,695 (GRCm38)		probably benign	Het
Ppp1r3f	C	A	X: 7,560,336 (GRCm38)	G562V	probably damaging	Homo
Ppp2r5c	G	T	12: 110,540,738 (GRCm38)		probably null	Homo
Prag1	CCGC	CCGCCGC	8: 36,103,883 (GRCm38)		probably benign	Homo
Prr13	CTC	CTCTTC	15: 102,462,176 (GRCm38)		probably benign	Homo
Prr13	CACT	CACTACT	15: 102,462,171 (GRCm38)		probably benign	Homo
Ptms	TCT	TCTCCT	6: 124,914,454 (GRCm38)		probably benign	Homo
Ptpn23	G	T	9: 110,387,633 (GRCm38)	P1052T	probably benign	Homo
Raph1	GG	GGGGG	1: 60,489,267 (GRCm38)		probably benign	Homo
Rpa1	TGCTGCC	T	11: 75,318,519 (GRCm38)		probably benign	Het
Rpgrip1	GGAAGAAGA	GGA	14: 52,149,544 (GRCm38)		probably benign	Het
Rpgrip1	GGA	GGATGA	14: 52,149,394 (GRCm38)		probably benign	Het
Rps19	AGCGG	AG	7: 24,888,996 (GRCm38)		probably benign	Homo
Rsf1	G	GACC	7: 97,579,909 (GRCm38)		probably benign	Homo
Serpina3m	A	G	12: 104,358,623 (GRCm38)		probably null	Homo
Setd1a	TGGTGGTGGT	TGGTGGTGGTGGTGGTGGT	7: 127,785,307 (GRCm38)		probably benign	Homo
Setd1a	TAGTGGTGG	TAGTGGTGGGAGTGGTGG	7: 127,785,316 (GRCm38)		probably benign	Het
Sfswap	ACTCAGCCC	ACTCAGCCCCCTCAGCCC	5: 129,569,751 (GRCm38)		probably benign	Het
Sh3pxd2b	CCTGTG	CCTGTGTCTGTG	11: 32,423,055 (GRCm38)		probably benign	Het
Sh3pxd2b	GCCTGT	GCCTGTGCCTGT	11: 32,423,060 (GRCm38)		probably benign	Homo
Shroom4	GCAGCAACA	GCA	X: 6,624,074 (GRCm38)		probably benign	Het
Six3	CG	CGGGG	17: 85,621,371 (GRCm38)		probably benign	Het
Six3	GCG	GCGTCG	17: 85,621,358 (GRCm38)		probably benign	Het
Skint8	C	T	4: 111,938,902 (GRCm38)	L258F	probably benign	Homo
Smoc2	AGTT	A	17: 14,401,562 (GRCm38)		probably benign	Homo
Smpx	CCCCCA	C	X: 157,720,924 (GRCm38)		probably benign	Homo
Snx1	TC	TCTGC	9: 66,104,929 (GRCm38)		probably benign	Homo
Snx1	C	CTTT	9: 66,104,930 (GRCm38)		probably benign	Homo
Sp110	CT	CTAAT	1: 85,587,489 (GRCm38)		probably benign	Het
Spaca1	GCTCTC	GCTCTCCCTCTC	4: 34,049,844 (GRCm38)		probably benign	Het
Spaca1	CGCTCT	CGCTCTTGCTCT	4: 34,049,849 (GRCm38)		probably benign	Het
Spag17	GGA	GGACGA	3: 100,056,255 (GRCm38)		probably benign	Het
Spag17	AGG	AGGTGG	3: 100,056,254 (GRCm38)		probably benign	Het
Srebf2	G	T	15: 82,185,335 (GRCm38)	A693S	probably damaging	Homo
Sry	T	TGGG	Y: 2,662,841 (GRCm38)		probably benign	Homo
Stard8	AGG	AGGTGG	X: 99,066,513 (GRCm38)		probably benign	Het
Stard8	AGG	AGGTGG	X: 99,066,525 (GRCm38)		probably benign	Het
Stk10	CCCA	C	11: 32,614,520 (GRCm38)		probably benign	Homo
Tap2	ACTG	ACTGCTG	17: 34,205,699 (GRCm38)		probably benign	Homo
Tbc1d5	G	C	17: 50,799,931 (GRCm38)	H532Q	probably benign	Homo
Tbc1d5	C	G	17: 50,799,943 (GRCm38)	Q528H	probably benign	Homo
Tfeb	GCA	GCAACA	17: 47,786,094 (GRCm38)		probably benign	Het
Tmcc1	G	A	6: 116,193,380 (GRCm38)		probably benign	Homo
Tob1	AGC	AGCCGC	11: 94,214,472 (GRCm38)		probably benign	Het
Tpsab1	TTGCACCTCCT	TT	17: 25,343,782 (GRCm38)		probably benign	Het
Trav15-2-dv6-2	G	GAAC	14: 53,649,757 (GRCm38)		probably benign	Homo
Trav15-2-dv6-2	GAA	GAATAA	14: 53,649,754 (GRCm38)		probably null	Het
Trim16	GTGA	GTGATGA	11: 62,820,689 (GRCm38)		probably benign	Homo
Tsen2	AGG	AGGCGG	6: 115,560,066 (GRCm38)		probably benign	Homo
Ubtf	TC	TCCGC	11: 102,306,959 (GRCm38)		probably benign	Het
Vmn1r124	G	T	7: 21,259,936 (GRCm38)	Q228K	possibly damaging	Het
Vmn1r71	A	C	7: 10,748,121 (GRCm38)	S147R	probably benign	Homo
Vmn2r99	G	A	17: 19,394,285 (GRCm38)	G756R	probably damaging	Homo
Vps13b	G	T	15: 35,846,957 (GRCm38)	A2629S	probably damaging	Homo
Wdr75	AAATAA	AAA	1: 45,823,404 (GRCm38)		probably benign	Homo
Zfp111	T	G	7: 24,199,037 (GRCm38)	K383T	probably damaging	Homo
Zfp111	A	ATCG	7: 24,199,807 (GRCm38)		probably benign	Homo
Zfp26	C	A	9: 20,438,546 (GRCm38)	A241S	probably benign	Homo
Zfp282	CGG	CGGTGG	6: 47,904,790 (GRCm38)		probably benign	Het
Zfp335	TCC	TCCACC	2: 164,907,478 (GRCm38)		probably benign	Het
Zfp335	CTC	CTCTTC	2: 164,907,474 (GRCm38)		probably benign	Het
Zfp459	A	AGTGG	13: 67,408,276 (GRCm38)		probably null	Homo
Zfp459	GA	GAGTTA	13: 67,408,275 (GRCm38)		probably null	Homo
Zfp459	TGA	TGAGAGA	13: 67,408,274 (GRCm38)		probably null	Homo
Zfp462	CC	CCTCAGCCACAGCCATC	4: 55,009,761 (GRCm38)		probably benign	Het
Zfp462	ACC	ACCTCAGCCACAGCCGCC	4: 55,009,760 (GRCm38)		probably benign	Het
Zfp598	ACCACC	ACCACCCCCACC	17: 24,680,782 (GRCm38)		probably benign	Het
Zfp598	CCACAGGC	CC	17: 24,679,372 (GRCm38)		probably benign	Het
Zfp683	AG	AGGGG	4: 134,058,879 (GRCm38)		probably benign	Homo

Other mutations in Kmt2c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00436:Kmt2c	APN	5	25,281,261 (GRCm38)	missense	probably damaging	0.99
IGL00694:Kmt2c	APN	5	25,293,161 (GRCm38)	missense	probably damaging	0.99
IGL00780:Kmt2c	APN	5	25,311,051 (GRCm38)	missense	probably benign	0.00
IGL00811:Kmt2c	APN	5	25,374,533 (GRCm38)	missense	possibly damaging	0.75
IGL00885:Kmt2c	APN	5	25,409,171 (GRCm38)	missense	possibly damaging	0.80
IGL00948:Kmt2c	APN	5	25,377,161 (GRCm38)	missense	probably benign	0.08
IGL00959:Kmt2c	APN	5	25,276,229 (GRCm38)	missense	probably damaging	1.00
IGL01022:Kmt2c	APN	5	25,302,701 (GRCm38)	unclassified	probably benign
IGL01146:Kmt2c	APN	5	25,308,512 (GRCm38)	missense	probably damaging	0.96
IGL01154:Kmt2c	APN	5	25,284,399 (GRCm38)	missense	probably damaging	1.00
IGL01434:Kmt2c	APN	5	25,409,308 (GRCm38)	missense	probably damaging	1.00
IGL01464:Kmt2c	APN	5	25,352,244 (GRCm38)	missense	possibly damaging	0.90
IGL01525:Kmt2c	APN	5	25,329,441 (GRCm38)	splice site	probably benign
IGL01530:Kmt2c	APN	5	25,313,500 (GRCm38)	missense	probably benign	0.08
IGL01550:Kmt2c	APN	5	25,281,276 (GRCm38)	missense	probably damaging	1.00
IGL01598:Kmt2c	APN	5	25,273,666 (GRCm38)	makesense	probably null
IGL01598:Kmt2c	APN	5	25,354,771 (GRCm38)	missense	probably damaging	1.00
IGL01608:Kmt2c	APN	5	25,354,811 (GRCm38)	missense	probably damaging	0.97
IGL01663:Kmt2c	APN	5	25,310,670 (GRCm38)	missense	probably damaging	1.00
IGL01707:Kmt2c	APN	5	25,300,098 (GRCm38)	missense	probably damaging	1.00
IGL01714:Kmt2c	APN	5	25,313,400 (GRCm38)	missense	probably benign
IGL01784:Kmt2c	APN	5	25,313,526 (GRCm38)	missense	probably damaging	1.00
IGL01813:Kmt2c	APN	5	25,290,804 (GRCm38)	missense	possibly damaging	0.82
IGL01825:Kmt2c	APN	5	25,310,596 (GRCm38)	missense	probably damaging	1.00
IGL01834:Kmt2c	APN	5	25,395,455 (GRCm38)	missense	probably benign	0.05
IGL02072:Kmt2c	APN	5	25,405,432 (GRCm38)	missense	possibly damaging	0.96
IGL02159:Kmt2c	APN	5	25,311,343 (GRCm38)	missense	probably benign	0.18
IGL02303:Kmt2c	APN	5	25,310,157 (GRCm38)	missense	probably damaging	0.96
IGL02417:Kmt2c	APN	5	25,373,020 (GRCm38)	missense	probably benign
IGL02578:Kmt2c	APN	5	25,366,200 (GRCm38)	intron	probably benign
IGL02811:Kmt2c	APN	5	25,315,028 (GRCm38)	nonsense	probably null
IGL02943:Kmt2c	APN	5	25,290,823 (GRCm38)	missense	probably damaging	1.00
IGL03000:Kmt2c	APN	5	25,284,172 (GRCm38)	missense	probably damaging	1.00
IGL03040:Kmt2c	APN	5	25,310,352 (GRCm38)	missense	probably benign
IGL03076:Kmt2c	APN	5	25,299,151 (GRCm38)	nonsense	probably null
IGL03088:Kmt2c	APN	5	25,299,804 (GRCm38)	missense	probably damaging	0.99
IGL03131:Kmt2c	APN	5	25,315,361 (GRCm38)	missense	probably benign	0.00
FR4304:Kmt2c	UTSW	5	25,315,766 (GRCm38)	small insertion	probably benign
PIT4520001:Kmt2c	UTSW	5	25,315,666 (GRCm38)	missense	probably benign	0.12
PIT4585001:Kmt2c	UTSW	5	25,315,106 (GRCm38)	missense	probably benign	0.21
R0313:Kmt2c	UTSW	5	25,344,930 (GRCm38)	missense	probably damaging	1.00
R0374:Kmt2c	UTSW	5	25,309,708 (GRCm38)	missense	probably damaging	1.00
R0411:Kmt2c	UTSW	5	25,375,957 (GRCm38)	missense	probably damaging	1.00
R0422:Kmt2c	UTSW	5	25,315,664 (GRCm38)	missense	probably benign
R0453:Kmt2c	UTSW	5	25,354,747 (GRCm38)	missense	probably damaging	1.00
R0616:Kmt2c	UTSW	5	25,299,252 (GRCm38)	missense	probably benign
R0619:Kmt2c	UTSW	5	25,298,916 (GRCm38)	missense	probably benign	0.21
R0671:Kmt2c	UTSW	5	25,404,365 (GRCm38)	missense	probably damaging	1.00
R0736:Kmt2c	UTSW	5	25,295,434 (GRCm38)	missense	probably benign
R0745:Kmt2c	UTSW	5	25,359,698 (GRCm38)	splice site	probably null
R0760:Kmt2c	UTSW	5	25,353,317 (GRCm38)	missense	possibly damaging	0.68
R0784:Kmt2c	UTSW	5	25,310,895 (GRCm38)	missense	probably benign	0.00
R0882:Kmt2c	UTSW	5	25,295,607 (GRCm38)	missense	possibly damaging	0.90
R0893:Kmt2c	UTSW	5	25,351,270 (GRCm38)	splice site	probably benign
R0942:Kmt2c	UTSW	5	25,315,303 (GRCm38)	missense	probably benign	0.10
R1110:Kmt2c	UTSW	5	25,314,362 (GRCm38)	missense	probably benign	0.01
R1137:Kmt2c	UTSW	5	25,310,983 (GRCm38)	missense	possibly damaging	0.80
R1255:Kmt2c	UTSW	5	25,351,153 (GRCm38)	missense	probably damaging	1.00
R1300:Kmt2c	UTSW	5	25,405,454 (GRCm38)	missense	probably damaging	0.99
R1497:Kmt2c	UTSW	5	25,314,515 (GRCm38)	missense	possibly damaging	0.80
R1594:Kmt2c	UTSW	5	25,314,878 (GRCm38)	missense	probably benign	0.01
R1611:Kmt2c	UTSW	5	25,359,311 (GRCm38)	critical splice donor site	probably null
R1617:Kmt2c	UTSW	5	25,375,927 (GRCm38)	missense	probably benign	0.01
R1720:Kmt2c	UTSW	5	25,299,184 (GRCm38)	missense	probably benign	0.05
R1723:Kmt2c	UTSW	5	25,315,005 (GRCm38)	missense	probably damaging	1.00
R1724:Kmt2c	UTSW	5	25,315,005 (GRCm38)	missense	probably damaging	1.00
R1726:Kmt2c	UTSW	5	25,315,005 (GRCm38)	missense	probably damaging	1.00
R1736:Kmt2c	UTSW	5	25,290,527 (GRCm38)	missense	probably damaging	1.00
R1778:Kmt2c	UTSW	5	25,372,974 (GRCm38)	missense	probably benign	0.02
R1809:Kmt2c	UTSW	5	25,284,192 (GRCm38)	missense	probably damaging	1.00
R1845:Kmt2c	UTSW	5	25,373,436 (GRCm38)	missense	probably benign	0.45
R1895:Kmt2c	UTSW	5	25,315,154 (GRCm38)	missense	probably benign	0.34
R1946:Kmt2c	UTSW	5	25,315,154 (GRCm38)	missense	probably benign	0.34
R1989:Kmt2c	UTSW	5	25,498,544 (GRCm38)	missense	possibly damaging	0.93
R2039:Kmt2c	UTSW	5	25,329,040 (GRCm38)	missense	possibly damaging	0.53
R2049:Kmt2c	UTSW	5	25,285,079 (GRCm38)	missense	probably damaging	1.00
R2079:Kmt2c	UTSW	5	25,352,280 (GRCm38)	missense	possibly damaging	0.82
R2080:Kmt2c	UTSW	5	25,354,717 (GRCm38)	missense	probably damaging	1.00
R2107:Kmt2c	UTSW	5	25,309,824 (GRCm38)	missense	probably benign	0.01
R2186:Kmt2c	UTSW	5	25,287,112 (GRCm38)	missense	probably damaging	1.00
R2395:Kmt2c	UTSW	5	25,315,152 (GRCm38)	missense	probably benign
R2983:Kmt2c	UTSW	5	25,315,757 (GRCm38)	small deletion	probably benign
R3109:Kmt2c	UTSW	5	25,275,735 (GRCm38)	missense	probably damaging	1.00
R3500:Kmt2c	UTSW	5	25,299,479 (GRCm38)	missense	probably benign	0.02
R3738:Kmt2c	UTSW	5	25,405,383 (GRCm38)	missense	probably benign	0.41
R3809:Kmt2c	UTSW	5	25,409,138 (GRCm38)	missense	possibly damaging	0.87
R4088:Kmt2c	UTSW	5	25,287,713 (GRCm38)	missense	probably benign
R4107:Kmt2c	UTSW	5	25,298,920 (GRCm38)	missense	possibly damaging	0.51
R4212:Kmt2c	UTSW	5	25,347,359 (GRCm38)	critical splice donor site	probably null
R4376:Kmt2c	UTSW	5	25,315,326 (GRCm38)	missense	probably benign	0.00
R4377:Kmt2c	UTSW	5	25,315,326 (GRCm38)	missense	probably benign	0.00
R4383:Kmt2c	UTSW	5	25,351,062 (GRCm38)	missense	possibly damaging	0.77
R4435:Kmt2c	UTSW	5	25,314,877 (GRCm38)	missense	possibly damaging	0.63
R4456:Kmt2c	UTSW	5	25,310,212 (GRCm38)	missense	probably benign
R4461:Kmt2c	UTSW	5	25,299,876 (GRCm38)	missense	probably benign	0.00
R4519:Kmt2c	UTSW	5	25,363,477 (GRCm38)	missense	probably damaging	1.00
R4550:Kmt2c	UTSW	5	25,300,174 (GRCm38)	missense	probably damaging	1.00
R4557:Kmt2c	UTSW	5	25,300,315 (GRCm38)	missense	probably damaging	1.00
R4610:Kmt2c	UTSW	5	25,354,384 (GRCm38)	missense	probably damaging	1.00
R4671:Kmt2c	UTSW	5	25,366,177 (GRCm38)	missense	probably damaging	1.00
R4704:Kmt2c	UTSW	5	25,314,027 (GRCm38)	nonsense	probably null
R4781:Kmt2c	UTSW	5	25,443,825 (GRCm38)	missense	probably damaging	1.00
R4844:Kmt2c	UTSW	5	25,315,113 (GRCm38)	missense	probably benign
R4855:Kmt2c	UTSW	5	25,314,557 (GRCm38)	missense	probably benign	0.00
R4919:Kmt2c	UTSW	5	25,314,395 (GRCm38)	missense	possibly damaging	0.80
R4971:Kmt2c	UTSW	5	25,310,872 (GRCm38)	missense	probably benign	0.00
R4983:Kmt2c	UTSW	5	25,295,511 (GRCm38)	missense	possibly damaging	0.51
R5012:Kmt2c	UTSW	5	25,299,712 (GRCm38)	nonsense	probably null
R5033:Kmt2c	UTSW	5	25,314,708 (GRCm38)	missense	probably benign	0.03
R5093:Kmt2c	UTSW	5	25,409,207 (GRCm38)	missense	probably benign	0.17
R5125:Kmt2c	UTSW	5	25,284,381 (GRCm38)	missense	probably damaging	0.99
R5231:Kmt2c	UTSW	5	25,315,473 (GRCm38)	missense	possibly damaging	0.89
R5254:Kmt2c	UTSW	5	25,314,594 (GRCm38)	missense	probably benign	0.01
R5396:Kmt2c	UTSW	5	25,294,734 (GRCm38)	splice site	probably null
R5415:Kmt2c	UTSW	5	25,314,701 (GRCm38)	missense	probably benign	0.21
R5523:Kmt2c	UTSW	5	25,299,339 (GRCm38)	missense	probably benign	0.00
R5554:Kmt2c	UTSW	5	25,294,610 (GRCm38)	missense	probably damaging	1.00
R5701:Kmt2c	UTSW	5	25,314,017 (GRCm38)	missense	probably benign	0.16
R5762:Kmt2c	UTSW	5	25,310,457 (GRCm38)	missense	probably benign	0.01
R5819:Kmt2c	UTSW	5	25,409,132 (GRCm38)	critical splice donor site	probably null
R5838:Kmt2c	UTSW	5	25,284,471 (GRCm38)	missense	probably damaging	1.00
R5912:Kmt2c	UTSW	5	25,347,469 (GRCm38)	missense	possibly damaging	0.80
R5951:Kmt2c	UTSW	5	25,330,803 (GRCm38)	missense	probably benign	0.15
R5988:Kmt2c	UTSW	5	25,311,120 (GRCm38)	missense	probably benign	0.02
R5999:Kmt2c	UTSW	5	25,284,205 (GRCm38)	missense	probably damaging	1.00
R6104:Kmt2c	UTSW	5	25,299,129 (GRCm38)	missense	probably benign
R6254:Kmt2c	UTSW	5	25,349,874 (GRCm38)	missense	possibly damaging	0.94
R6311:Kmt2c	UTSW	5	25,443,818 (GRCm38)	critical splice donor site	probably null
R6329:Kmt2c	UTSW	5	25,315,602 (GRCm38)	missense	probably benign	0.01
R6347:Kmt2c	UTSW	5	25,310,835 (GRCm38)	missense	possibly damaging	0.54
R6364:Kmt2c	UTSW	5	25,309,636 (GRCm38)	missense	probably null	0.99
R6379:Kmt2c	UTSW	5	25,359,341 (GRCm38)	missense	probably damaging	1.00
R6588:Kmt2c	UTSW	5	25,323,789 (GRCm38)	missense	probably damaging	0.99
R6628:Kmt2c	UTSW	5	25,298,928 (GRCm38)	missense	probably benign
R6733:Kmt2c	UTSW	5	25,409,293 (GRCm38)	missense	probably damaging	1.00
R6787:Kmt2c	UTSW	5	25,275,739 (GRCm38)	splice site	probably null
R6816:Kmt2c	UTSW	5	25,405,532 (GRCm38)	splice site	probably null
R6862:Kmt2c	UTSW	5	25,310,517 (GRCm38)	missense	probably damaging	1.00
R7150:Kmt2c	UTSW	5	25,300,362 (GRCm38)	missense	possibly damaging	0.89
R7220:Kmt2c	UTSW	5	25,344,925 (GRCm38)	missense	probably damaging	1.00
R7250:Kmt2c	UTSW	5	25,309,807 (GRCm38)	missense	probably benign	0.00
R7250:Kmt2c	UTSW	5	25,299,491 (GRCm38)	missense	probably damaging	1.00
R7402:Kmt2c	UTSW	5	25,395,420 (GRCm38)	missense	probably damaging	1.00
R7465:Kmt2c	UTSW	5	25,302,849 (GRCm38)	missense	probably damaging	1.00
R7467:Kmt2c	UTSW	5	25,308,532 (GRCm38)	missense	probably damaging	1.00
R7491:Kmt2c	UTSW	5	25,284,564 (GRCm38)	missense	probably damaging	0.99
R7549:Kmt2c	UTSW	5	25,414,970 (GRCm38)	missense	possibly damaging	0.95
R7637:Kmt2c	UTSW	5	25,315,095 (GRCm38)	missense	probably damaging	1.00
R7652:Kmt2c	UTSW	5	25,315,719 (GRCm38)	missense	probably benign	0.01
R7714:Kmt2c	UTSW	5	25,375,366 (GRCm38)	missense	probably benign
R7838:Kmt2c	UTSW	5	25,294,699 (GRCm38)	missense	possibly damaging	0.57
R7891:Kmt2c	UTSW	5	25,300,111 (GRCm38)	missense	probably damaging	1.00
R7892:Kmt2c	UTSW	5	25,299,816 (GRCm38)	missense	probably benign	0.18
R7895:Kmt2c	UTSW	5	25,373,176 (GRCm38)	missense	possibly damaging	0.65
R7960:Kmt2c	UTSW	5	25,315,196 (GRCm38)	missense	probably benign	0.01
R7974:Kmt2c	UTSW	5	25,300,563 (GRCm38)	missense	probably damaging	1.00
R7978:Kmt2c	UTSW	5	25,359,678 (GRCm38)	missense	probably benign	0.00
R8011:Kmt2c	UTSW	5	25,351,234 (GRCm38)	missense	probably damaging	0.99
R8021:Kmt2c	UTSW	5	25,287,119 (GRCm38)	missense	possibly damaging	0.88
R8022:Kmt2c	UTSW	5	25,281,680 (GRCm38)	missense	possibly damaging	0.83
R8079:Kmt2c	UTSW	5	25,302,732 (GRCm38)	missense	probably damaging	0.98
R8087:Kmt2c	UTSW	5	25,329,252 (GRCm38)	missense	probably damaging	1.00
R8109:Kmt2c	UTSW	5	25,281,384 (GRCm38)	missense	probably damaging	1.00
R8161:Kmt2c	UTSW	5	25,374,564 (GRCm38)	missense	probably benign	0.00
R8169:Kmt2c	UTSW	5	25,354,687 (GRCm38)	missense	probably damaging	1.00
R8206:Kmt2c	UTSW	5	25,314,539 (GRCm38)	missense	probably damaging	0.98
R8218:Kmt2c	UTSW	5	25,283,106 (GRCm38)	missense	probably damaging	1.00
R8223:Kmt2c	UTSW	5	25,324,218 (GRCm38)	missense	possibly damaging	0.89
R8260:Kmt2c	UTSW	5	25,405,516 (GRCm38)	missense	possibly damaging	0.87
R8330:Kmt2c	UTSW	5	25,304,694 (GRCm38)	missense	probably null	1.00
R8355:Kmt2c	UTSW	5	25,354,501 (GRCm38)	critical splice acceptor site	probably null
R8455:Kmt2c	UTSW	5	25,354,501 (GRCm38)	critical splice acceptor site	probably null
R8508:Kmt2c	UTSW	5	25,314,122 (GRCm38)	missense	probably benign	0.34
R8885:Kmt2c	UTSW	5	25,315,079 (GRCm38)	missense	probably benign	0.34
R8907:Kmt2c	UTSW	5	25,309,611 (GRCm38)	missense	probably damaging	1.00
R8924:Kmt2c	UTSW	5	25,298,887 (GRCm38)	missense	probably benign
R8969:Kmt2c	UTSW	5	25,314,389 (GRCm38)	missense	possibly damaging	0.82
R9019:Kmt2c	UTSW	5	25,283,210 (GRCm38)	missense	probably damaging	1.00
R9035:Kmt2c	UTSW	5	25,319,012 (GRCm38)	missense	probably damaging	1.00
R9074:Kmt2c	UTSW	5	25,284,345 (GRCm38)	missense	probably damaging	1.00
R9125:Kmt2c	UTSW	5	25,284,196 (GRCm38)	missense	possibly damaging	0.86
R9130:Kmt2c	UTSW	5	25,311,104 (GRCm38)	missense	probably benign	0.01
R9171:Kmt2c	UTSW	5	25,281,311 (GRCm38)	missense	probably damaging	1.00
R9235:Kmt2c	UTSW	5	25,299,999 (GRCm38)	missense	probably damaging	1.00
R9288:Kmt2c	UTSW	5	25,349,862 (GRCm38)	missense	probably benign	0.34
R9288:Kmt2c	UTSW	5	25,292,909 (GRCm38)	missense	probably damaging	1.00
R9336:Kmt2c	UTSW	5	25,409,167 (GRCm38)	missense	probably benign	0.06
R9443:Kmt2c	UTSW	5	25,310,047 (GRCm38)	missense	probably damaging	1.00
R9481:Kmt2c	UTSW	5	25,292,909 (GRCm38)	missense	probably damaging	1.00
R9481:Kmt2c	UTSW	5	25,349,862 (GRCm38)	missense	probably benign	0.34
R9526:Kmt2c	UTSW	5	25,281,357 (GRCm38)	missense	probably damaging	1.00
R9653:Kmt2c	UTSW	5	25,302,821 (GRCm38)	missense	probably damaging	1.00
R9729:Kmt2c	UTSW	5	25,284,760 (GRCm38)	missense	probably damaging	1.00
R9731:Kmt2c	UTSW	5	25,372,958 (GRCm38)	missense	probably benign	0.18
R9784:Kmt2c	UTSW	5	25,344,961 (GRCm38)	missense	probably damaging	1.00
RF001:Kmt2c	UTSW	5	25,315,775 (GRCm38)	small insertion	probably benign
RF006:Kmt2c	UTSW	5	25,315,772 (GRCm38)	small insertion	probably benign
RF011:Kmt2c	UTSW	5	25,338,459 (GRCm38)	missense	probably damaging	1.00
RF041:Kmt2c	UTSW	5	25,315,775 (GRCm38)	small insertion	probably benign
RF047:Kmt2c	UTSW	5	25,315,760 (GRCm38)	small insertion	probably benign
RF051:Kmt2c	UTSW	5	25,313,479 (GRCm38)	unclassified	probably benign
RF055:Kmt2c	UTSW	5	25,315,772 (GRCm38)	small insertion	probably benign
RF059:Kmt2c	UTSW	5	25,313,479 (GRCm38)	unclassified	probably benign
RF063:Kmt2c	UTSW	5	25,315,764 (GRCm38)	small insertion	probably benign
X0024:Kmt2c	UTSW	5	25,405,485 (GRCm38)	missense	probably benign	0.26
X0027:Kmt2c	UTSW	5	25,330,887 (GRCm38)	missense	possibly damaging	0.90
Z1176:Kmt2c	UTSW	5	25,354,413 (GRCm38)	missense	probably damaging	1.00
Z1177:Kmt2c	UTSW	5	25,366,197 (GRCm38)	critical splice acceptor site	probably null
Z1177:Kmt2c	UTSW	5	25,300,003 (GRCm38)	missense	probably benign	0.00
Z1177:Kmt2c	UTSW	5	25,295,397 (GRCm38)	critical splice donor site	probably null

Predicted Primers

PCR Primer
(F):5'- AGGTTGTGGTTTGACAAACAC -3'
(R):5'- AGGCATCAATAGGACATAATCTGC -3'

Sequencing Primer
(F):5'- GTGGTTTGACAAACACACCATCTG -3'
(R):5'- TAGGACATAATCTGCTACCTACTGAC -3'

Posted On

2018-04-05