Incidental Mutation 'IGL01145:Gm5868'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5868
Ensembl Gene ENSMUSG00000060204
Gene Namepredicted gene 5868
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.373) question?
Stock #IGL01145
Quality Score
Chromosomal Location72581638-72587551 bp(-) (GRCm38)
Type of Mutationcritical splice donor site (2 bp from exon)
DNA Base Change (assembly) A to T at 72586204 bp
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000031124 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000031124] [ENSMUST00000073528]
Predicted Effect probably null
Transcript: ENSMUST00000031124
SMART Domains Protein: ENSMUSP00000031124
Gene: ENSMUSG00000060204

transmembrane domain 20 42 N/A INTRINSIC
transmembrane domain 54 76 N/A INTRINSIC
transmembrane domain 91 113 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000073528
SMART Domains Protein: ENSMUSP00000073221
Gene: ENSMUSG00000063935

zf-3CxxC 262 347 5.2e-24 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 35 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acan A C 7: 79,099,282 D1267A probably damaging Het
AI314180 A C 4: 58,811,501 D1467E probably null Het
Ankrd44 A G 1: 54,762,259 probably null Het
Arap3 T C 18: 37,989,179 M619V probably benign Het
C8b A T 4: 104,780,580 Y83F probably benign Het
Capn15 A G 17: 25,963,050 V595A probably damaging Het
Cbx1 A T 11: 96,801,566 D93V probably benign Het
Cyp2c66 G T 19: 39,170,961 E285D probably benign Het
Dkk4 T A 8: 22,625,386 V84D probably damaging Het
Dnah17 T A 11: 118,047,173 I3343F possibly damaging Het
Dus3l T C 17: 56,767,627 probably benign Het
Eif6 A G 2: 155,826,435 probably benign Het
Eya3 A G 4: 132,709,995 I389V probably damaging Het
Gm5916 A T 9: 36,120,702 D95E unknown Het
Gucy2d T A 7: 98,449,963 S329T probably benign Het
Hook3 C T 8: 26,059,344 M157I probably benign Het
Iapp C A 6: 142,303,364 R48S probably damaging Het
Ints11 A G 4: 155,885,126 Y153C probably damaging Het
Layn G A 9: 51,074,046 T62I probably benign Het
Llgl2 A G 11: 115,853,805 H876R probably benign Het
Lrp4 T C 2: 91,487,051 I840T probably damaging Het
Myo9a T A 9: 59,855,375 F796L probably benign Het
Naip1 A G 13: 100,409,121 S1300P probably benign Het
Nfat5 T A 8: 107,367,215 I602N probably damaging Het
Omt2a T C 9: 78,312,956 M64V probably benign Het
Pcnx T C 12: 81,992,035 S2025P probably damaging Het
Pemt A G 11: 59,983,467 L62P probably damaging Het
Polrmt A G 10: 79,741,137 V399A probably benign Het
Rasgrp4 T C 7: 29,151,473 S77P possibly damaging Het
Rrm2b G A 15: 37,944,560 P111L probably damaging Het
Thap12 A G 7: 98,712,903 *121W probably null Het
Tnik A G 3: 28,604,167 probably benign Het
Trio G A 15: 27,818,167 probably benign Het
Zfhx4 A G 3: 5,245,347 E930G probably damaging Het
Zfp335 G T 2: 164,907,502 T299K probably benign Het
Other mutations in Gm5868
AlleleSourceChrCoordTypePredicted EffectPPH Score
R2318:Gm5868 UTSW 5 72586295 missense probably benign 0.00
R4096:Gm5868 UTSW 5 72586366 missense probably damaging 1.00
R7002:Gm5868 UTSW 5 72586420 critical splice acceptor site probably null
Z1177:Gm5868 UTSW 5 72586346 missense probably benign 0.01
Posted On2013-06-21