Incidental Mutation 'IGL01062:Vmn1r10'
ID51228
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r10
Ensembl Gene ENSMUSG00000115181
Gene Namevomeronasal 1 receptor 10
SynonymsV1rc1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.154) question?
Stock #IGL01062
Quality Score
Status
Chromosome6
Chromosomal Location57109454-57115035 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 57113836 bp
ZygosityHeterozygous
Amino Acid Change Serine to Glycine at position 138 (S138G)
Ref Sequence ENSEMBL: ENSMUSP00000154213 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000176073] [ENSMUST00000228270]
Predicted Effect possibly damaging
Transcript: ENSMUST00000176073
AA Change: S138G

PolyPhen 2 Score 0.698 (Sensitivity: 0.86; Specificity: 0.92)
SMART Domains Protein: ENSMUSP00000134901
Gene: ENSMUSG00000115181
AA Change: S138G

DomainStartEndE-ValueType
Pfam:V1R 28 293 4.1e-55 PFAM
Predicted Effect possibly damaging
Transcript: ENSMUST00000228270
AA Change: S138G

PolyPhen 2 Score 0.698 (Sensitivity: 0.86; Specificity: 0.92)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1110017D15Rik T A 4: 41,511,433 E93D probably damaging Het
Aen G A 7: 78,907,302 M299I probably damaging Het
Amer3 A G 1: 34,586,739 K20E probably damaging Het
Arhgap31 A G 16: 38,601,456 L1416P probably damaging Het
Avpr1a G A 10: 122,449,529 C242Y probably damaging Het
Bclaf3 T C X: 159,553,419 Y281H probably benign Het
Cdc14a T A 3: 116,274,712 probably benign Het
Cfap206 C T 4: 34,721,562 S162N probably damaging Het
Cntn4 T C 6: 106,618,278 probably benign Het
Cyp3a44 T A 5: 145,794,339 D217V possibly damaging Het
Eprs A G 1: 185,379,615 E274G probably benign Het
Ercc6l2 G T 13: 63,847,454 Q354H probably null Het
Glb1l A T 1: 75,201,238 I392N probably damaging Het
Gm3173 T C 14: 4,514,887 probably null Het
Grasp A G 15: 101,228,896 probably benign Het
Hadh C T 3: 131,240,991 V219M probably damaging Het
Hspb9 A G 11: 100,713,935 H29R possibly damaging Het
Iqgap3 G T 3: 88,110,122 V240L probably benign Het
Jmjd1c T C 10: 67,226,715 S1616P probably damaging Het
Knl1 A G 2: 119,076,980 I1662V probably benign Het
Mapre3 A G 5: 30,864,896 I236V probably benign Het
Med17 T C 9: 15,279,621 E58G probably benign Het
Myh6 T C 14: 54,952,292 E1099G probably damaging Het
Myt1 T A 2: 181,797,729 V348D probably damaging Het
Nat10 A T 2: 103,743,048 I368N probably damaging Het
Nol6 T C 4: 41,118,205 I811V probably benign Het
Oas1d C A 5: 120,919,064 Y244* probably null Het
Olfr49 A T 14: 54,282,724 M57K probably damaging Het
Osbpl1a A G 18: 12,905,075 V273A probably benign Het
Pigw T C 11: 84,877,943 R187G probably benign Het
Plekhg5 G A 4: 152,108,496 D603N probably damaging Het
Ptprk T C 10: 28,580,418 V1058A probably damaging Het
Robo4 G A 9: 37,406,000 S537N probably benign Het
Rptn T A 3: 93,397,182 F607L probably benign Het
Sall1 A G 8: 89,033,344 V44A probably damaging Het
Sh3bp4 C A 1: 89,143,960 Q177K probably benign Het
Srrt C A 5: 137,296,307 G779V probably damaging Het
Tex21 T C 12: 76,198,944 D526G probably benign Het
Tmem57 A T 4: 134,833,297 V125E probably damaging Het
Ttc37 T A 13: 76,155,462 L1225* probably null Het
Yars2 C T 16: 16,306,542 R338* probably null Het
Zfp454 T C 11: 50,874,206 E22G probably benign Het
Zzef1 T A 11: 72,874,969 C1441S probably benign Het
Other mutations in Vmn1r10
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL03255:Vmn1r10 APN 6 57113926 missense probably benign 0.05
IGL03393:Vmn1r10 APN 6 57114057 nonsense probably null
R0310:Vmn1r10 UTSW 6 57113501 missense probably damaging 0.97
R2271:Vmn1r10 UTSW 6 57114103 missense probably damaging 1.00
R2411:Vmn1r10 UTSW 6 57114139 missense probably benign 0.14
R3700:Vmn1r10 UTSW 6 57114302 missense probably benign 0.05
R3731:Vmn1r10 UTSW 6 57113734 missense probably damaging 0.99
R4805:Vmn1r10 UTSW 6 57113617 missense possibly damaging 0.94
R4922:Vmn1r10 UTSW 6 57113826 missense probably damaging 0.99
R5697:Vmn1r10 UTSW 6 57113489 missense probably damaging 1.00
R5936:Vmn1r10 UTSW 6 57114317 missense probably benign 0.01
R6119:Vmn1r10 UTSW 6 57114233 missense probably benign 0.01
R7107:Vmn1r10 UTSW 6 57113630 missense possibly damaging 0.90
R7531:Vmn1r10 UTSW 6 57113939 missense possibly damaging 0.90
R7635:Vmn1r10 UTSW 6 57114041 missense probably benign 0.00
R7860:Vmn1r10 UTSW 6 57113701 missense probably benign 0.19
R7943:Vmn1r10 UTSW 6 57113701 missense probably benign 0.19
Posted On2013-06-21