Incidental Mutation 'IGL01093:Zfp9'
| ID |
51295 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp9
|
| Ensembl Gene |
ENSMUSG00000072623 |
| Gene Name |
zinc finger protein 9 |
| Synonyms |
Zfp-9, Krox-4, 1810048F22Rik |
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.399)
|
| Stock # |
IGL01093
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
6 |
| Chromosomal Location |
118438911-118456281 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 118442800 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Threonine
at position 99
(A99T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123810
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000161170]
|
| AlphaFold |
Q8BIS1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161170
AA Change: A99T
PolyPhen 2
Score 0.145 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000123810
Gene: ENSMUSG00000072623
AA Change: A99T
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
8 |
68 |
2.26e-31 |
SMART |
|
ZnF_C2H2
|
117 |
139 |
1.82e-3 |
SMART |
|
ZnF_C2H2
|
144 |
166 |
4.17e-3 |
SMART |
|
ZnF_C2H2
|
172 |
194 |
5.99e-4 |
SMART |
|
ZnF_C2H2
|
200 |
222 |
2.79e-4 |
SMART |
|
ZnF_C2H2
|
228 |
250 |
1.56e-2 |
SMART |
|
ZnF_C2H2
|
256 |
278 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
284 |
306 |
7.9e-4 |
SMART |
|
ZnF_C2H2
|
312 |
334 |
2.75e-3 |
SMART |
|
ZnF_C2H2
|
340 |
362 |
5.14e-3 |
SMART |
|
ZnF_C2H2
|
368 |
390 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
396 |
418 |
1.6e-4 |
SMART |
|
ZnF_C2H2
|
424 |
446 |
9.08e-4 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000204066
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 29 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Akr1c21 |
C |
T |
13: 4,631,139 (GRCm39) |
|
probably benign |
Het |
| Alpk2 |
A |
G |
18: 65,482,400 (GRCm39) |
L69P |
probably damaging |
Het |
| C3 |
G |
T |
17: 57,530,949 (GRCm39) |
P384Q |
probably damaging |
Het |
| Cobll1 |
T |
C |
2: 64,928,581 (GRCm39) |
E953G |
probably damaging |
Het |
| Dnaaf9 |
T |
C |
2: 130,619,156 (GRCm39) |
T281A |
probably benign |
Het |
| Dnmt1 |
C |
T |
9: 20,821,081 (GRCm39) |
E1269K |
possibly damaging |
Het |
| Dync2h1 |
T |
C |
9: 7,145,611 (GRCm39) |
R1012G |
probably benign |
Het |
| Fbxw24 |
T |
A |
9: 109,434,041 (GRCm39) |
Q423L |
probably benign |
Het |
| Flg2 |
T |
C |
3: 93,109,678 (GRCm39) |
S569P |
unknown |
Het |
| Ier5 |
A |
G |
1: 154,975,139 (GRCm39) |
I13T |
probably damaging |
Het |
| Kat6a |
A |
G |
8: 23,429,337 (GRCm39) |
D1564G |
possibly damaging |
Het |
| Lcn5 |
T |
C |
2: 25,550,729 (GRCm39) |
V139A |
probably benign |
Het |
| Naca |
A |
G |
10: 127,883,982 (GRCm39) |
S2138G |
probably damaging |
Het |
| Or1j15 |
T |
G |
2: 36,458,838 (GRCm39) |
V76G |
probably damaging |
Het |
| Or5p59 |
T |
A |
7: 107,702,851 (GRCm39) |
S112T |
probably benign |
Het |
| Or5w14 |
T |
G |
2: 87,541,477 (GRCm39) |
M258L |
possibly damaging |
Het |
| Or6c66 |
A |
C |
10: 129,461,432 (GRCm39) |
F166C |
probably damaging |
Het |
| Or6c74 |
A |
G |
10: 129,869,761 (GRCm39) |
T89A |
probably benign |
Het |
| Pcdhgb8 |
A |
G |
18: 37,958,089 (GRCm39) |
T813A |
probably damaging |
Het |
| Pkd1l1 |
T |
C |
11: 8,851,345 (GRCm39) |
T696A |
probably benign |
Het |
| Rif1 |
T |
G |
2: 51,985,960 (GRCm39) |
H648Q |
probably damaging |
Het |
| Secisbp2l |
C |
A |
2: 125,582,245 (GRCm39) |
K1070N |
probably benign |
Het |
| Spock3 |
G |
A |
8: 63,801,993 (GRCm39) |
R327Q |
probably benign |
Het |
| Trpm2 |
A |
G |
10: 77,768,114 (GRCm39) |
I795T |
probably benign |
Het |
| Ube4b |
T |
C |
4: 149,414,726 (GRCm39) |
I1128V |
probably benign |
Het |
| Vmn1r225 |
A |
T |
17: 20,723,081 (GRCm39) |
D174V |
probably damaging |
Het |
| Xpnpep3 |
T |
A |
15: 81,320,969 (GRCm39) |
Y283N |
possibly damaging |
Het |
| Zfp944 |
A |
G |
17: 22,562,615 (GRCm39) |
|
probably benign |
Het |
| Zscan4c |
G |
A |
7: 10,743,544 (GRCm39) |
C381Y |
probably benign |
Het |
|
| Other mutations in Zfp9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00336:Zfp9
|
APN |
6 |
118,441,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01512:Zfp9
|
APN |
6 |
118,444,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0491:Zfp9
|
UTSW |
6 |
118,442,163 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1716:Zfp9
|
UTSW |
6 |
118,441,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1858:Zfp9
|
UTSW |
6 |
118,442,021 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4088:Zfp9
|
UTSW |
6 |
118,441,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4490:Zfp9
|
UTSW |
6 |
118,442,273 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4627:Zfp9
|
UTSW |
6 |
118,441,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4951:Zfp9
|
UTSW |
6 |
118,441,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5344:Zfp9
|
UTSW |
6 |
118,442,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5594:Zfp9
|
UTSW |
6 |
118,442,000 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6198:Zfp9
|
UTSW |
6 |
118,454,282 (GRCm39) |
start codon destroyed |
probably null |
|
|
R6682:Zfp9
|
UTSW |
6 |
118,444,202 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6986:Zfp9
|
UTSW |
6 |
118,441,426 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7147:Zfp9
|
UTSW |
6 |
118,441,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7799:Zfp9
|
UTSW |
6 |
118,441,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7921:Zfp9
|
UTSW |
6 |
118,442,032 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R7934:Zfp9
|
UTSW |
6 |
118,441,847 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8111:Zfp9
|
UTSW |
6 |
118,441,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8369:Zfp9
|
UTSW |
6 |
118,441,353 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8916:Zfp9
|
UTSW |
6 |
118,442,223 (GRCm39) |
nonsense |
probably null |
|
|
R9660:Zfp9
|
UTSW |
6 |
118,443,851 (GRCm39) |
missense |
probably benign |
|
|
R9728:Zfp9
|
UTSW |
6 |
118,443,851 (GRCm39) |
missense |
probably benign |
|
|
| Posted On |
2013-06-21 |
Incidental Mutation