Incidental Mutation 'IGL01146:1810009J06Rik'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 1810009J06Rik
Ensembl Gene ENSMUSG00000094808
Gene NameRIKEN cDNA 1810009J06 gene
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.162) question?
Stock #IGL01146
Quality Score
Chromosomal Location40964754-40968435 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 40966283 bp
Amino Acid Change Isoleucine to Threonine at position 54 (I54T)
Ref Sequence ENSEMBL: ENSMUSP00000075935 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000076638]
Predicted Effect probably damaging
Transcript: ENSMUST00000076638
AA Change: I54T

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000075935
Gene: ENSMUSG00000094808
AA Change: I54T

Tryp_SPc 23 240 4.94e-97 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4921501E09Rik A G 17: 33,065,383 L815S possibly damaging Het
4930402H24Rik C T 2: 130,770,671 probably null Het
Acss2 T C 2: 155,562,037 V701A possibly damaging Het
Adam6a A T 12: 113,544,220 Y71F probably damaging Het
Arhgef37 A T 18: 61,518,010 I148N possibly damaging Het
Bhlhe40 T C 6: 108,664,940 S282P possibly damaging Het
Bmp2 A T 2: 133,561,300 Q257L probably benign Het
C2cd4d A G 3: 94,364,463 probably benign Het
Calcr T A 6: 3,700,144 Y316F possibly damaging Het
Ccdc186 T C 19: 56,809,317 E274G probably damaging Het
Cdc34b G T 11: 94,742,594 D207Y probably benign Het
Chst5 C T 8: 111,890,682 C102Y probably damaging Het
Cnbd2 T A 2: 156,312,614 probably benign Het
Dnm1l T C 16: 16,314,325 D549G probably benign Het
Gm4847 T A 1: 166,634,952 D323V probably damaging Het
Gm9843 G A 16: 76,403,367 noncoding transcript Het
Gopc A G 10: 52,358,867 V120A probably benign Het
Kmt2c T G 5: 25,308,512 M3095L probably damaging Het
Man1a T C 10: 53,907,519 E629G possibly damaging Het
Pde4b T A 4: 102,255,263 S12T possibly damaging Het
Phf2 A T 13: 48,819,607 L391Q unknown Het
Plekha7 G A 7: 116,157,473 probably benign Het
Pmpcb T A 5: 21,740,478 probably benign Het
Poc1a T C 9: 106,305,304 Y285H probably benign Het
Polr1e T C 4: 45,031,369 L387S probably damaging Het
Prr9 A T 3: 92,123,197 C45* probably null Het
Rnf157 T C 11: 116,350,086 H393R probably benign Het
Rps6ka4 A G 19: 6,831,128 F554L probably damaging Het
Sez6l A G 5: 112,428,409 S861P probably damaging Het
Sh3tc2 G T 18: 61,989,511 D448Y probably damaging Het
Smg6 T G 11: 74,930,428 Y508* probably null Het
Sult6b2 C T 6: 142,804,308 G28D probably benign Het
Traf2 C A 2: 25,524,919 C303F probably benign Het
Other mutations in 1810009J06Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00741:1810009J06Rik APN 6 40964834 splice site probably benign
IGL00952:1810009J06Rik APN 6 40964799 missense probably benign 0.00
IGL02815:1810009J06Rik APN 6 40964795 missense probably benign
R1543:1810009J06Rik UTSW 6 40968204 missense probably damaging 1.00
R1708:1810009J06Rik UTSW 6 40964798 missense probably benign
R1964:1810009J06Rik UTSW 6 40968207 missense probably damaging 1.00
R5786:1810009J06Rik UTSW 6 40968188 missense probably damaging 1.00
R6611:1810009J06Rik UTSW 6 40966779 missense probably benign 0.09
R7057:1810009J06Rik UTSW 6 40968247 missense probably benign 0.00
Posted On2013-06-21