Incidental Mutation 'R6376:Nrp2'
| ID |
514943 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nrp2
|
| Ensembl Gene |
ENSMUSG00000025969 |
| Gene Name |
neuropilin 2 |
| Synonyms |
1110048P06Rik, NP-2, Npn-2, NP2, Npn2 |
| MMRRC Submission |
044526-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.958)
|
| Stock # |
R6376 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
62742476-62857851 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 62758176 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 54
(N54S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109794
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000027112]
[ENSMUST00000063594]
[ENSMUST00000075144]
[ENSMUST00000102822]
[ENSMUST00000114155]
[ENSMUST00000114157]
|
| AlphaFold |
O35375 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000027112
AA Change: N54S
PolyPhen 2
Score 0.652 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000027112
Gene: ENSMUSG00000025969
AA Change: N54S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
CUB
|
28 |
142 |
3.4e-45 |
SMART |
|
CUB
|
149 |
267 |
1.04e-40 |
SMART |
|
FA58C
|
276 |
427 |
1.63e-45 |
SMART |
|
FA58C
|
433 |
592 |
9.33e-14 |
SMART |
|
MAM
|
641 |
802 |
2.31e-60 |
SMART |
|
Pfam:DUF3481
|
822 |
906 |
1.4e-35 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000063594
AA Change: N54S
PolyPhen 2
Score 0.652 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000069379
Gene: ENSMUSG00000025969
AA Change: N54S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
CUB
|
28 |
142 |
3.4e-45 |
SMART |
|
CUB
|
149 |
267 |
1.04e-40 |
SMART |
|
FA58C
|
276 |
427 |
1.63e-45 |
SMART |
|
FA58C
|
433 |
592 |
9.33e-14 |
SMART |
|
MAM
|
641 |
802 |
2.31e-60 |
SMART |
|
low complexity region
|
816 |
831 |
N/A |
INTRINSIC |
|
Pfam:DUF3481
|
839 |
923 |
1.6e-25 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000075144
AA Change: N54S
PolyPhen 2
Score 0.652 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000074642
Gene: ENSMUSG00000025969
AA Change: N54S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
CUB
|
28 |
142 |
3.4e-45 |
SMART |
|
CUB
|
149 |
267 |
1.04e-40 |
SMART |
|
FA58C
|
276 |
427 |
1.63e-45 |
SMART |
|
FA58C
|
433 |
592 |
9.33e-14 |
SMART |
|
MAM
|
641 |
802 |
2.31e-60 |
SMART |
|
Pfam:DUF3481
|
827 |
911 |
2.3e-25 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102822
AA Change: N54S
PolyPhen 2
Score 0.008 (Sensitivity: 0.96; Specificity: 0.76)
|
| SMART Domains |
Protein: ENSMUSP00000099886
Gene: ENSMUSG00000025969
AA Change: N54S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
CUB
|
28 |
142 |
3.4e-45 |
SMART |
|
CUB
|
149 |
267 |
1.04e-40 |
SMART |
|
FA58C
|
276 |
427 |
1.63e-45 |
SMART |
|
FA58C
|
433 |
592 |
9.33e-14 |
SMART |
|
MAM
|
641 |
802 |
2.31e-60 |
SMART |
|
Pfam:DUF3481
|
822 |
906 |
2.3e-25 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000114155
AA Change: N54S
PolyPhen 2
Score 0.652 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000109792
Gene: ENSMUSG00000025969
AA Change: N54S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
CUB
|
28 |
142 |
3.4e-45 |
SMART |
|
CUB
|
149 |
267 |
1.04e-40 |
SMART |
|
FA58C
|
276 |
427 |
1.63e-45 |
SMART |
|
FA58C
|
433 |
592 |
9.33e-14 |
SMART |
|
MAM
|
641 |
802 |
2.31e-60 |
SMART |
|
Pfam:DUF3481
|
817 |
901 |
9.4e-36 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000114157
AA Change: N54S
PolyPhen 2
Score 0.652 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000109794
Gene: ENSMUSG00000025969
AA Change: N54S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
CUB
|
28 |
142 |
3.4e-45 |
SMART |
|
CUB
|
149 |
267 |
1.04e-40 |
SMART |
|
FA58C
|
276 |
427 |
1.63e-45 |
SMART |
|
FA58C
|
433 |
592 |
9.33e-14 |
SMART |
|
MAM
|
641 |
802 |
2.31e-60 |
SMART |
|
low complexity region
|
821 |
836 |
N/A |
INTRINSIC |
|
Pfam:DUF3481
|
844 |
928 |
2.4e-25 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000126344
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000189205
|
| Meta Mutation Damage Score |
0.0924 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.4%
- 20x: 97.8%
|
| Validation Efficiency |
100% (81/81) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Nullizygous mice may exhibit pre- or postnatal lethality, reduced fertility, hydrocephalus, aberrant sensory innervation, reduced interneuron count, seizure susceptibility and abnormal lymphangiogenesis. Homozygotes for a gene trap allele show abnormal neuronal development and axonal trajectories. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930550C14Rik |
A |
T |
9: 53,339,456 (GRCm39) |
E106D |
probably damaging |
Het |
| A830018L16Rik |
A |
T |
1: 11,868,718 (GRCm39) |
N333Y |
probably damaging |
Het |
| Abca4 |
T |
A |
3: 121,917,309 (GRCm39) |
M1007K |
possibly damaging |
Het |
| Accsl |
T |
A |
2: 93,687,343 (GRCm39) |
I495F |
probably damaging |
Het |
| Acsl3 |
T |
C |
1: 78,674,182 (GRCm39) |
S373P |
possibly damaging |
Het |
| Adam7 |
A |
G |
14: 68,742,546 (GRCm39) |
I689T |
possibly damaging |
Het |
| Akap11 |
G |
A |
14: 78,752,336 (GRCm39) |
T179I |
probably damaging |
Het |
| Ankmy1 |
T |
C |
1: 92,816,187 (GRCm39) |
K309R |
possibly damaging |
Het |
| Apaf1 |
A |
T |
10: 90,859,673 (GRCm39) |
I824N |
probably damaging |
Het |
| Apc2 |
T |
A |
10: 80,148,488 (GRCm39) |
C1152S |
probably damaging |
Het |
| Arhgap17 |
C |
A |
7: 122,899,727 (GRCm39) |
W409L |
probably damaging |
Het |
| Arhgef15 |
T |
C |
11: 68,845,796 (GRCm39) |
I19V |
unknown |
Het |
| Arnt |
C |
A |
3: 95,397,936 (GRCm39) |
P573H |
probably damaging |
Het |
| Arvcf |
G |
A |
16: 18,223,882 (GRCm39) |
G932R |
probably damaging |
Het |
| Atg4a-ps |
C |
T |
3: 103,553,044 (GRCm39) |
W99* |
probably null |
Het |
| Atp13a5 |
T |
A |
16: 29,056,004 (GRCm39) |
D1052V |
probably benign |
Het |
| Atp2b4 |
T |
C |
1: 133,642,797 (GRCm39) |
T1103A |
probably damaging |
Het |
| B4galnt4 |
C |
A |
7: 140,647,335 (GRCm39) |
Q362K |
possibly damaging |
Het |
| Cd320 |
T |
A |
17: 34,066,491 (GRCm39) |
N90K |
probably benign |
Het |
| Cep170b |
A |
T |
12: 112,698,502 (GRCm39) |
I87F |
probably damaging |
Het |
| Coq3 |
T |
G |
4: 21,900,486 (GRCm39) |
C238G |
probably benign |
Het |
| Cpa5 |
A |
T |
6: 30,614,044 (GRCm39) |
Q62L |
probably benign |
Het |
| Ctsg |
A |
T |
14: 56,339,110 (GRCm39) |
C49* |
probably null |
Het |
| Cul9 |
T |
C |
17: 46,819,489 (GRCm39) |
T2000A |
probably damaging |
Het |
| Dedd |
C |
T |
1: 171,167,790 (GRCm39) |
P155S |
probably benign |
Het |
| Dnah1 |
A |
G |
14: 30,997,565 (GRCm39) |
S2598P |
probably damaging |
Het |
| Dnah14 |
C |
T |
1: 181,433,459 (GRCm39) |
P379S |
possibly damaging |
Het |
| Dync2h1 |
A |
T |
9: 7,165,703 (GRCm39) |
S519R |
probably benign |
Het |
| Eea1 |
A |
G |
10: 95,874,660 (GRCm39) |
S1192G |
probably benign |
Het |
| Eif5b |
T |
C |
1: 38,084,760 (GRCm39) |
I869T |
probably damaging |
Het |
| Elavl4 |
C |
A |
4: 110,112,651 (GRCm39) |
|
probably benign |
Het |
| Eml2 |
G |
A |
7: 18,935,088 (GRCm39) |
V432I |
probably damaging |
Het |
| Ets2 |
G |
A |
16: 95,520,037 (GRCm39) |
R421H |
probably damaging |
Het |
| Exoc3l2 |
G |
A |
7: 19,203,635 (GRCm39) |
A76T |
possibly damaging |
Het |
| Fam89b |
T |
C |
19: 5,778,757 (GRCm39) |
Y144C |
probably damaging |
Het |
| Greb1 |
T |
C |
12: 16,749,580 (GRCm39) |
E1082G |
probably damaging |
Het |
| Gtf3a |
A |
T |
5: 146,890,798 (GRCm39) |
|
probably null |
Het |
| Hoxc12 |
C |
A |
15: 102,845,524 (GRCm39) |
F79L |
possibly damaging |
Het |
| Hspb8 |
G |
T |
5: 116,547,491 (GRCm39) |
L164I |
probably damaging |
Het |
| Ina |
C |
T |
19: 47,003,564 (GRCm39) |
A124V |
probably benign |
Het |
| Inhbb |
T |
A |
1: 119,345,411 (GRCm39) |
I293F |
probably damaging |
Het |
| Itpr3 |
A |
G |
17: 27,314,449 (GRCm39) |
Y633C |
possibly damaging |
Het |
| Jag2 |
C |
T |
12: 112,872,949 (GRCm39) |
V1102I |
probably benign |
Het |
| Kalrn |
A |
T |
16: 33,796,361 (GRCm39) |
F1138Y |
probably benign |
Het |
| Large2 |
T |
A |
2: 92,200,853 (GRCm39) |
|
probably benign |
Het |
| Lats2 |
A |
G |
14: 57,959,966 (GRCm39) |
S177P |
probably benign |
Het |
| Lims2 |
G |
A |
18: 32,087,515 (GRCm39) |
R124H |
possibly damaging |
Het |
| Lrp2 |
T |
A |
2: 69,313,787 (GRCm39) |
T2315S |
probably benign |
Het |
| Lrrc4c |
A |
C |
2: 97,459,391 (GRCm39) |
T6P |
probably benign |
Het |
| Lrrk2 |
T |
C |
15: 91,626,469 (GRCm39) |
L1171S |
possibly damaging |
Het |
| Man2b2 |
A |
T |
5: 36,978,378 (GRCm39) |
M302K |
probably damaging |
Het |
| Mocos |
G |
A |
18: 24,834,542 (GRCm39) |
G860R |
possibly damaging |
Het |
| Mylk3 |
T |
A |
8: 86,085,571 (GRCm39) |
D258V |
possibly damaging |
Het |
| Nkx1-2 |
C |
T |
7: 132,201,240 (GRCm39) |
D6N |
probably damaging |
Het |
| Nt5el |
T |
C |
13: 105,256,473 (GRCm39) |
I514T |
possibly damaging |
Het |
| Or2d2 |
A |
G |
7: 106,727,848 (GRCm39) |
F251L |
probably benign |
Het |
| Pacsin1 |
A |
T |
17: 27,926,879 (GRCm39) |
T195S |
probably benign |
Het |
| Pank4 |
T |
C |
4: 155,056,693 (GRCm39) |
|
probably null |
Het |
| Pdgfra |
A |
T |
5: 75,327,180 (GRCm39) |
M126L |
probably benign |
Het |
| Podxl |
T |
A |
6: 31,505,432 (GRCm39) |
T204S |
probably benign |
Het |
| Pole |
G |
A |
5: 110,484,240 (GRCm39) |
D2175N |
probably damaging |
Het |
| Pramel16 |
C |
T |
4: 143,677,267 (GRCm39) |
G104E |
probably benign |
Het |
| Prkdc |
A |
G |
16: 15,587,749 (GRCm39) |
K2545E |
probably benign |
Het |
| Prodh |
T |
C |
16: 17,897,849 (GRCm39) |
I183V |
probably benign |
Het |
| Ptch1 |
T |
C |
13: 63,691,422 (GRCm39) |
D277G |
possibly damaging |
Het |
| Rapgef5 |
G |
A |
12: 117,684,988 (GRCm39) |
V246M |
probably damaging |
Het |
| Rubcnl |
A |
G |
14: 75,269,834 (GRCm39) |
N164S |
probably benign |
Het |
| Samd4 |
A |
T |
14: 47,290,419 (GRCm39) |
L175F |
probably damaging |
Het |
| Scart1 |
G |
A |
7: 139,808,642 (GRCm39) |
G851D |
probably damaging |
Het |
| Scimp |
C |
A |
11: 70,688,893 (GRCm39) |
W41L |
possibly damaging |
Het |
| Scn3a |
T |
A |
2: 65,291,843 (GRCm39) |
K1634N |
possibly damaging |
Het |
| Spta1 |
A |
G |
1: 174,030,888 (GRCm39) |
R957G |
probably benign |
Het |
| Sptlc3 |
T |
A |
2: 139,478,692 (GRCm39) |
N550K |
probably benign |
Het |
| Srebf1 |
T |
C |
11: 60,094,361 (GRCm39) |
N609D |
probably null |
Het |
| Styxl1 |
A |
T |
5: 135,776,664 (GRCm39) |
L164H |
probably benign |
Het |
| Synpo2l |
A |
T |
14: 20,710,702 (GRCm39) |
D865E |
probably damaging |
Het |
| Tnfsf15 |
T |
C |
4: 63,663,267 (GRCm39) |
M19V |
probably damaging |
Het |
| Trappc8 |
G |
C |
18: 20,970,132 (GRCm39) |
R953G |
probably benign |
Het |
| Trav13-1 |
A |
G |
14: 53,782,800 (GRCm39) |
N50S |
probably benign |
Het |
| Trim12a |
T |
C |
7: 103,955,241 (GRCm39) |
K161E |
probably benign |
Het |
| Vipr1 |
C |
A |
9: 121,493,640 (GRCm39) |
N230K |
probably damaging |
Het |
| Xirp1 |
A |
T |
9: 119,847,557 (GRCm39) |
V3E |
probably damaging |
Het |
| Zfp768 |
A |
G |
7: 126,943,892 (GRCm39) |
F82L |
probably benign |
Het |
|
| Other mutations in Nrp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00765:Nrp2
|
APN |
1 |
62,743,410 (GRCm39) |
nonsense |
probably null |
|
|
IGL01912:Nrp2
|
APN |
1 |
62,810,896 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01996:Nrp2
|
APN |
1 |
62,788,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02184:Nrp2
|
APN |
1 |
62,758,099 (GRCm39) |
nonsense |
probably null |
|
|
IGL02682:Nrp2
|
APN |
1 |
62,810,996 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02928:Nrp2
|
APN |
1 |
62,854,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03024:Nrp2
|
APN |
1 |
62,810,893 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Euphorbia
|
UTSW |
1 |
62,801,972 (GRCm39) |
missense |
probably benign |
0.02 |
|
Sabra
|
UTSW |
1 |
62,822,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0068:Nrp2
|
UTSW |
1 |
62,784,536 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0068:Nrp2
|
UTSW |
1 |
62,784,536 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0683:Nrp2
|
UTSW |
1 |
62,783,477 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0789:Nrp2
|
UTSW |
1 |
62,784,609 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1418:Nrp2
|
UTSW |
1 |
62,822,491 (GRCm39) |
nonsense |
probably null |
|
|
R1468:Nrp2
|
UTSW |
1 |
62,777,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Nrp2
|
UTSW |
1 |
62,777,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Nrp2
|
UTSW |
1 |
62,802,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1645:Nrp2
|
UTSW |
1 |
62,824,283 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1677:Nrp2
|
UTSW |
1 |
62,822,479 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1752:Nrp2
|
UTSW |
1 |
62,777,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1840:Nrp2
|
UTSW |
1 |
62,777,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1916:Nrp2
|
UTSW |
1 |
62,801,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Nrp2
|
UTSW |
1 |
62,758,090 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2108:Nrp2
|
UTSW |
1 |
62,783,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2164:Nrp2
|
UTSW |
1 |
62,783,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2216:Nrp2
|
UTSW |
1 |
62,802,077 (GRCm39) |
nonsense |
probably null |
|
|
R2679:Nrp2
|
UTSW |
1 |
62,824,237 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4349:Nrp2
|
UTSW |
1 |
62,777,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4351:Nrp2
|
UTSW |
1 |
62,777,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4352:Nrp2
|
UTSW |
1 |
62,777,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4353:Nrp2
|
UTSW |
1 |
62,777,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4811:Nrp2
|
UTSW |
1 |
62,758,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5362:Nrp2
|
UTSW |
1 |
62,808,221 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5387:Nrp2
|
UTSW |
1 |
62,801,972 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5461:Nrp2
|
UTSW |
1 |
62,786,370 (GRCm39) |
nonsense |
probably null |
|
|
R5704:Nrp2
|
UTSW |
1 |
62,824,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6143:Nrp2
|
UTSW |
1 |
62,799,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6303:Nrp2
|
UTSW |
1 |
62,784,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6304:Nrp2
|
UTSW |
1 |
62,784,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6945:Nrp2
|
UTSW |
1 |
62,799,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Nrp2
|
UTSW |
1 |
62,784,663 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7393:Nrp2
|
UTSW |
1 |
62,784,583 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7593:Nrp2
|
UTSW |
1 |
62,758,203 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7881:Nrp2
|
UTSW |
1 |
62,810,990 (GRCm39) |
missense |
probably benign |
0.42 |
|
R7882:Nrp2
|
UTSW |
1 |
62,822,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7948:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7958:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7959:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7960:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7961:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8009:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8012:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8014:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8015:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8068:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8069:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8070:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8071:Nrp2
|
UTSW |
1 |
62,784,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8206:Nrp2
|
UTSW |
1 |
62,786,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8791:Nrp2
|
UTSW |
1 |
62,788,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9090:Nrp2
|
UTSW |
1 |
62,784,670 (GRCm39) |
missense |
probably benign |
0.21 |
|
R9271:Nrp2
|
UTSW |
1 |
62,784,670 (GRCm39) |
missense |
probably benign |
0.21 |
|
R9287:Nrp2
|
UTSW |
1 |
62,835,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9469:Nrp2
|
UTSW |
1 |
62,804,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9646:Nrp2
|
UTSW |
1 |
62,777,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9752:Nrp2
|
UTSW |
1 |
62,851,726 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTCCTGGGTTGCCATAAAAGGTTC -3'
(R):5'- TTTAAGTGGCCCTCTGTGGC -3'
Sequencing Primer
(F):5'- GGGTTGCCATAAAAGGTTCTCAAAC -3'
(R):5'- CTAGGGCCCACAACTGC -3'
|
| Posted On |
2018-05-04 |
Incidental Mutation