Incidental Mutation 'R6377:Clip1'
| ID |
515039 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clip1
|
| Ensembl Gene |
ENSMUSG00000049550 |
| Gene Name |
CAP-GLY domain containing linker protein 1 |
| Synonyms |
Rsn, CLIP-170, 4631429H07Rik, restin, Clip 170, 1110007I12Rik, Clip50, cytoplasmic linker protein 50 |
| MMRRC Submission |
044527-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6377 (G1)
|
| Quality Score |
192.009 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
123715857-123822527 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 123741717 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1053
(V1053A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000068241
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000031382]
[ENSMUST00000063905]
[ENSMUST00000111561]
[ENSMUST00000111564]
[ENSMUST00000111566]
|
| AlphaFold |
Q922J3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000031382
AA Change: V1179A
PolyPhen 2
Score 0.259 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000031382
Gene: ENSMUSG00000049550
AA Change: V1179A
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
451 |
N/A |
INTRINSIC |
|
coiled coil region
|
474 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
581 |
620 |
N/A |
INTRINSIC |
|
coiled coil region
|
652 |
1352 |
N/A |
INTRINSIC |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1375 |
1392 |
5.8e-9 |
PFAM |
|
ZnF_C2HC
|
1417 |
1433 |
1.45e0 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000063905
AA Change: V1053A
PolyPhen 2
Score 0.500 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000068241
Gene: ENSMUSG00000049550
AA Change: V1053A
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1075 |
N/A |
INTRINSIC |
|
coiled coil region
|
1115 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1256 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1300 |
1316 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111561
AA Change: V1168A
PolyPhen 2
Score 0.190 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000107186
Gene: ENSMUSG00000049550
AA Change: V1168A
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1341 |
N/A |
INTRINSIC |
|
low complexity region
|
1351 |
1362 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1406 |
1422 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111564
AA Change: V1057A
PolyPhen 2
Score 0.153 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000107190
Gene: ENSMUSG00000049550
AA Change: V1057A
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1230 |
N/A |
INTRINSIC |
|
low complexity region
|
1240 |
1251 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1295 |
1311 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111566
AA Change: V1133A
PolyPhen 2
Score 0.044 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000107192
Gene: ENSMUSG00000049550
AA Change: V1133A
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1316 |
1327 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1371 |
1387 |
1.45e0 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000125340
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133545
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000137363
AA Change: V805A
|
| SMART Domains |
Protein: ENSMUSP00000121425
Gene: ENSMUSG00000049550
AA Change: V805A
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
2 |
31 |
2.59e0 |
SMART |
|
low complexity region
|
39 |
57 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
84 |
N/A |
INTRINSIC |
|
coiled coil region
|
101 |
276 |
N/A |
INTRINSIC |
|
coiled coil region
|
322 |
361 |
N/A |
INTRINSIC |
|
coiled coil region
|
393 |
980 |
N/A |
INTRINSIC |
|
low complexity region
|
991 |
1002 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1004 |
1021 |
4.2e-9 |
PFAM |
|
ZnF_C2HC
|
1046 |
1062 |
1.45e0 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000137602
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154432
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000154672
AA Change: V980A
|
| SMART Domains |
Protein: ENSMUSP00000122064
Gene: ENSMUSG00000049550
AA Change: V980A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
43 |
59 |
N/A |
INTRINSIC |
|
low complexity region
|
165 |
176 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
352 |
375 |
1.56e-8 |
PROSPERO |
|
internal_repeat_3
|
358 |
377 |
5.32e-6 |
PROSPERO |
|
internal_repeat_1
|
450 |
473 |
1.56e-8 |
PROSPERO |
|
internal_repeat_3
|
544 |
563 |
5.32e-6 |
PROSPERO |
|
internal_repeat_2
|
553 |
575 |
2.88e-7 |
PROSPERO |
|
low complexity region
|
735 |
744 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
781 |
803 |
2.88e-7 |
PROSPERO |
|
low complexity region
|
819 |
830 |
N/A |
INTRINSIC |
|
low complexity region
|
962 |
977 |
N/A |
INTRINSIC |
|
low complexity region
|
1081 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1110 |
1121 |
N/A |
INTRINSIC |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0580 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.4%
- 20x: 97.8%
|
| Validation Efficiency |
94% (59/63) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a targeted allele display reduced male fertility and teratozoospermia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 63 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ankib1 |
A |
G |
5: 3,743,855 (GRCm39) |
S812P |
possibly damaging |
Het |
| Atp2c2 |
A |
G |
8: 120,453,093 (GRCm39) |
E159G |
probably benign |
Het |
| Atrn |
A |
G |
2: 130,821,889 (GRCm39) |
I861V |
probably damaging |
Het |
| Cngb1 |
C |
A |
8: 95,975,608 (GRCm39) |
G629C |
probably damaging |
Het |
| Cntn5 |
A |
T |
9: 9,743,657 (GRCm39) |
F540Y |
probably damaging |
Het |
| Cpb1 |
A |
C |
3: 20,329,748 (GRCm39) |
|
probably null |
Het |
| Cyp4a14 |
A |
G |
4: 115,353,280 (GRCm39) |
Y11H |
probably benign |
Het |
| Dact2 |
A |
G |
17: 14,419,450 (GRCm39) |
S103P |
probably damaging |
Het |
| Dcstamp |
A |
T |
15: 39,618,317 (GRCm39) |
Y242F |
probably benign |
Het |
| Drd3 |
G |
T |
16: 43,641,670 (GRCm39) |
G329* |
probably null |
Het |
| Duxf1 |
T |
C |
10: 58,059,494 (GRCm39) |
|
probably benign |
Het |
| Dysf |
T |
A |
6: 83,985,945 (GRCm39) |
S17T |
probably benign |
Het |
| Eno1 |
A |
T |
4: 150,333,009 (GRCm39) |
K366N |
possibly damaging |
Het |
| Ffar2 |
C |
T |
7: 30,518,971 (GRCm39) |
V190I |
probably benign |
Het |
| Fkbp15 |
T |
C |
4: 62,242,429 (GRCm39) |
T508A |
probably damaging |
Het |
| Fndc1 |
A |
G |
17: 7,988,567 (GRCm39) |
V1165A |
unknown |
Het |
| Foxj3 |
A |
T |
4: 119,430,945 (GRCm39) |
|
probably null |
Het |
| Gabarap |
T |
C |
11: 69,882,630 (GRCm39) |
|
probably null |
Het |
| Gm19410 |
T |
A |
8: 36,270,736 (GRCm39) |
L1221* |
probably null |
Het |
| Gpat2 |
G |
C |
2: 127,273,838 (GRCm39) |
G294R |
possibly damaging |
Het |
| Igf1r |
A |
T |
7: 67,850,998 (GRCm39) |
Y931F |
probably benign |
Het |
| Il23r |
A |
T |
6: 67,400,636 (GRCm39) |
S565T |
probably damaging |
Het |
| Ipo8 |
A |
T |
6: 148,717,995 (GRCm39) |
Y209* |
probably null |
Het |
| Jph2 |
C |
T |
2: 163,181,632 (GRCm39) |
G511R |
probably benign |
Het |
| Khdrbs1 |
C |
A |
4: 129,635,890 (GRCm39) |
D22Y |
probably damaging |
Het |
| Kif5b |
A |
T |
18: 6,212,562 (GRCm39) |
L754Q |
probably damaging |
Het |
| Ksr1 |
C |
T |
11: 78,927,320 (GRCm39) |
|
probably null |
Het |
| L3mbtl4 |
G |
T |
17: 69,084,918 (GRCm39) |
V610F |
probably benign |
Het |
| Lars2 |
A |
G |
9: 123,283,825 (GRCm39) |
T698A |
probably benign |
Het |
| Lonp1 |
A |
G |
17: 56,928,961 (GRCm39) |
V267A |
possibly damaging |
Het |
| Loxhd1 |
T |
A |
18: 77,468,128 (GRCm39) |
D925E |
probably damaging |
Het |
| Lsg1 |
A |
G |
16: 30,393,386 (GRCm39) |
L187P |
possibly damaging |
Het |
| Mki67 |
A |
T |
7: 135,298,050 (GRCm39) |
V2328E |
possibly damaging |
Het |
| Mlh3 |
A |
G |
12: 85,315,271 (GRCm39) |
I305T |
probably damaging |
Het |
| Mtbp |
A |
G |
15: 55,421,016 (GRCm39) |
M1V |
probably null |
Het |
| Myadml2 |
C |
A |
11: 120,538,538 (GRCm39) |
C99F |
probably benign |
Het |
| Ncbp1 |
A |
G |
4: 46,150,703 (GRCm39) |
Y185C |
probably damaging |
Het |
| Ndufaf7 |
A |
T |
17: 79,250,739 (GRCm39) |
Q222L |
probably null |
Het |
| Nlrp4b |
A |
T |
7: 10,449,339 (GRCm39) |
Y147F |
probably benign |
Het |
| Or4c11c |
C |
T |
2: 88,661,613 (GRCm39) |
R51* |
probably null |
Het |
| Pet100 |
T |
C |
8: 3,672,370 (GRCm39) |
V15A |
probably benign |
Het |
| Pot1a |
A |
G |
6: 25,778,869 (GRCm39) |
V75A |
probably benign |
Het |
| Ptprs |
A |
T |
17: 56,725,935 (GRCm39) |
M1043K |
probably damaging |
Het |
| Rnf31 |
A |
G |
14: 55,832,984 (GRCm39) |
T413A |
probably damaging |
Het |
| Rsf1 |
ATGGCG |
ATGGCGACGGTGGCG |
7: 97,229,111 (GRCm39) |
|
probably benign |
Homo |
| Rsf1 |
CG |
CGACGGCGGTG |
7: 97,229,115 (GRCm39) |
|
probably benign |
Het |
| Rubcnl |
A |
T |
14: 75,287,635 (GRCm39) |
|
probably null |
Het |
| Ryr3 |
A |
T |
2: 112,462,530 (GRCm39) |
C4839S |
probably damaging |
Het |
| Scai |
A |
C |
2: 38,992,340 (GRCm39) |
D379E |
probably benign |
Het |
| Scd2 |
G |
T |
19: 44,288,198 (GRCm39) |
G197* |
probably null |
Het |
| Sdr39u1 |
A |
C |
14: 56,135,166 (GRCm39) |
I259S |
probably benign |
Het |
| Slco1a5 |
A |
T |
6: 142,187,906 (GRCm39) |
|
probably null |
Het |
| Sp1 |
A |
T |
15: 102,339,318 (GRCm39) |
T733S |
probably benign |
Het |
| Tecta |
A |
G |
9: 42,255,051 (GRCm39) |
S1711P |
probably damaging |
Het |
| Tedc1 |
G |
T |
12: 113,124,975 (GRCm39) |
W240L |
probably damaging |
Het |
| Trarg1 |
T |
C |
11: 76,571,355 (GRCm39) |
S124P |
probably damaging |
Het |
| Trim50 |
A |
G |
5: 135,382,454 (GRCm39) |
K102R |
probably benign |
Het |
| Utrn |
A |
G |
10: 12,619,827 (GRCm39) |
Y278H |
probably damaging |
Het |
| Vinac1 |
T |
A |
2: 128,878,731 (GRCm39) |
D1065V |
unknown |
Het |
| Vmn2r109 |
A |
C |
17: 20,784,796 (GRCm39) |
|
probably null |
Het |
| Zbed5 |
T |
C |
5: 129,932,210 (GRCm39) |
S720P |
possibly damaging |
Het |
| Zc3h3 |
A |
G |
15: 75,711,304 (GRCm39) |
S386P |
probably damaging |
Het |
| Zscan4-ps1 |
C |
T |
7: 10,802,418 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Clip1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Clip1
|
APN |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01067:Clip1
|
APN |
5 |
123,768,867 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01524:Clip1
|
APN |
5 |
123,717,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01632:Clip1
|
APN |
5 |
123,755,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01798:Clip1
|
APN |
5 |
123,721,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01874:Clip1
|
APN |
5 |
123,741,729 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL01908:Clip1
|
APN |
5 |
123,761,270 (GRCm39) |
splice site |
probably benign |
|
|
IGL02120:Clip1
|
APN |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02309:Clip1
|
APN |
5 |
123,755,763 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02555:Clip1
|
APN |
5 |
123,759,857 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03027:Clip1
|
APN |
5 |
123,759,919 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL03336:Clip1
|
APN |
5 |
123,791,633 (GRCm39) |
nonsense |
probably null |
|
|
IGL03365:Clip1
|
APN |
5 |
123,721,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02802:Clip1
|
UTSW |
5 |
123,769,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4812001:Clip1
|
UTSW |
5 |
123,768,738 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0254:Clip1
|
UTSW |
5 |
123,755,395 (GRCm39) |
splice site |
probably benign |
|
|
R0401:Clip1
|
UTSW |
5 |
123,791,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0530:Clip1
|
UTSW |
5 |
123,778,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0744:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0833:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1116:Clip1
|
UTSW |
5 |
123,717,554 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1182:Clip1
|
UTSW |
5 |
123,785,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1656:Clip1
|
UTSW |
5 |
123,768,466 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1700:Clip1
|
UTSW |
5 |
123,768,433 (GRCm39) |
missense |
probably benign |
|
|
R1889:Clip1
|
UTSW |
5 |
123,791,559 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1975:Clip1
|
UTSW |
5 |
123,761,281 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2406:Clip1
|
UTSW |
5 |
123,741,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3545:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3548:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3911:Clip1
|
UTSW |
5 |
123,728,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Clip1
|
UTSW |
5 |
123,755,892 (GRCm39) |
unclassified |
probably benign |
|
|
R4660:Clip1
|
UTSW |
5 |
123,717,437 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4784:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4785:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Clip1
|
UTSW |
5 |
123,769,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4831:Clip1
|
UTSW |
5 |
123,721,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4951:Clip1
|
UTSW |
5 |
123,768,408 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4960:Clip1
|
UTSW |
5 |
123,792,066 (GRCm39) |
nonsense |
probably null |
|
|
R5014:Clip1
|
UTSW |
5 |
123,755,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5116:Clip1
|
UTSW |
5 |
123,768,770 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5212:Clip1
|
UTSW |
5 |
123,768,744 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5238:Clip1
|
UTSW |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5318:Clip1
|
UTSW |
5 |
123,751,147 (GRCm39) |
unclassified |
probably benign |
|
|
R5372:Clip1
|
UTSW |
5 |
123,768,303 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5701:Clip1
|
UTSW |
5 |
123,751,366 (GRCm39) |
unclassified |
probably benign |
|
|
R5734:Clip1
|
UTSW |
5 |
123,753,217 (GRCm39) |
unclassified |
probably benign |
|
|
R5757:Clip1
|
UTSW |
5 |
123,765,460 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6024:Clip1
|
UTSW |
5 |
123,753,152 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6160:Clip1
|
UTSW |
5 |
123,751,604 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6177:Clip1
|
UTSW |
5 |
123,751,897 (GRCm39) |
unclassified |
probably benign |
|
|
R6183:Clip1
|
UTSW |
5 |
123,780,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6436:Clip1
|
UTSW |
5 |
123,779,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6471:Clip1
|
UTSW |
5 |
123,778,612 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6766:Clip1
|
UTSW |
5 |
123,752,827 (GRCm39) |
unclassified |
probably benign |
|
|
R7015:Clip1
|
UTSW |
5 |
123,751,675 (GRCm39) |
unclassified |
probably benign |
|
|
R7094:Clip1
|
UTSW |
5 |
123,761,333 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7143:Clip1
|
UTSW |
5 |
123,791,673 (GRCm39) |
missense |
probably benign |
|
|
R7222:Clip1
|
UTSW |
5 |
123,749,904 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7233:Clip1
|
UTSW |
5 |
123,749,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Clip1
|
UTSW |
5 |
123,751,328 (GRCm39) |
missense |
|
|
|
R7249:Clip1
|
UTSW |
5 |
123,741,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7283:Clip1
|
UTSW |
5 |
123,751,857 (GRCm39) |
missense |
|
|
|
R7295:Clip1
|
UTSW |
5 |
123,765,419 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7447:Clip1
|
UTSW |
5 |
123,791,696 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7458:Clip1
|
UTSW |
5 |
123,778,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7483:Clip1
|
UTSW |
5 |
123,755,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7516:Clip1
|
UTSW |
5 |
123,721,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7619:Clip1
|
UTSW |
5 |
123,752,342 (GRCm39) |
missense |
|
|
|
R7831:Clip1
|
UTSW |
5 |
123,751,342 (GRCm39) |
missense |
|
|
|
R7897:Clip1
|
UTSW |
5 |
123,760,861 (GRCm39) |
missense |
probably benign |
|
|
R8155:Clip1
|
UTSW |
5 |
123,751,699 (GRCm39) |
missense |
|
|
|
R8157:Clip1
|
UTSW |
5 |
123,768,782 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8232:Clip1
|
UTSW |
5 |
123,785,981 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8396:Clip1
|
UTSW |
5 |
123,780,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8446:Clip1
|
UTSW |
5 |
123,794,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8486:Clip1
|
UTSW |
5 |
123,752,770 (GRCm39) |
unclassified |
probably benign |
|
|
R8511:Clip1
|
UTSW |
5 |
123,791,969 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8731:Clip1
|
UTSW |
5 |
123,752,756 (GRCm39) |
missense |
|
|
|
R8889:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8892:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9058:Clip1
|
UTSW |
5 |
123,752,645 (GRCm39) |
missense |
|
|
|
R9106:Clip1
|
UTSW |
5 |
123,753,223 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9212:Clip1
|
UTSW |
5 |
123,721,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9217:Clip1
|
UTSW |
5 |
123,717,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9223:Clip1
|
UTSW |
5 |
123,784,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9325:Clip1
|
UTSW |
5 |
123,751,186 (GRCm39) |
missense |
|
|
|
R9752:Clip1
|
UTSW |
5 |
123,760,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Clip1
|
UTSW |
5 |
123,755,413 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TATAGCCGTGTGCATCCCTG -3'
(R):5'- TAGATCTTATCAGGCACGTGAC -3'
Sequencing Primer
(F):5'- TGCATCCCTGGAAGCAAAG -3'
(R):5'- AGGCACGTGACCCAGATCTATTTTC -3'
|
| Posted On |
2018-05-04 |
Incidental Mutation