Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01099:Vmn1r85'

51531

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r85

Ensembl Gene

ENSMUSG00000070817

Gene Name

vomeronasal 1 receptor 85

Synonyms

V1rj3

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.056) question?

Stock #

IGL01099

Quality Score

Status

Chromosome

Chromosomal Location

12818216-12819142 bp(-) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

T to A at 12818461 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Stop codon at position 228 (K228*)

Ref Sequence

ENSEMBL: ENSMUSP00000148178 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094829] [ENSMUST00000209822]

AlphaFold

Q8VIB8

Predicted Effect

probably null
Transcript: ENSMUST00000094829
AA Change: K228*

SMART Domains

Protein: ENSMUSP00000092424
Gene: ENSMUSG00000070817
AA Change: K228*

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	296	8.4e-18	PFAM
Pfam:V1R	24	298	2.5e-36	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000209822
AA Change: K228*

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 55 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca8a	G	A	11: 109,965,031 (GRCm39)		probably benign	Het
Adam28	A	G	14: 68,874,778 (GRCm39)		probably null	Het
Adcy10	A	G	1: 165,367,411 (GRCm39)	I560M	probably benign	Het
Alpl	G	A	4: 137,470,624 (GRCm39)		probably benign	Het
Ank1	G	A	8: 23,598,265 (GRCm39)	G753D	probably damaging	Het
Arhgef28	A	T	13: 98,090,480 (GRCm39)		probably benign	Het
Bmp7	A	T	2: 172,717,055 (GRCm39)	C329S	probably damaging	Het
Capn13	T	C	17: 73,658,504 (GRCm39)	D188G	probably damaging	Het
Car10	G	A	11: 93,469,516 (GRCm39)	E164K	possibly damaging	Het
Cfhr1	T	A	1: 139,475,497 (GRCm39)		probably benign	Het
Col11a1	C	T	3: 113,905,690 (GRCm39)	R562*	probably null	Het
Colec12	C	T	18: 9,848,826 (GRCm39)	R335C	probably damaging	Het
Cyb561d2	C	T	9: 107,417,488 (GRCm39)		probably null	Het
Epb41l3	A	G	17: 69,517,188 (GRCm39)	D72G	possibly damaging	Het
Etl4	T	C	2: 20,811,922 (GRCm39)	L1335P	probably benign	Het
F5	T	G	1: 164,021,903 (GRCm39)	N1459K	probably damaging	Het
Fam161a	T	C	11: 22,965,894 (GRCm39)		probably benign	Het
Flnc	G	A	6: 29,433,617 (GRCm39)	V54M	probably damaging	Het
Fndc3b	T	C	3: 27,517,966 (GRCm39)	I607V	probably benign	Het
Fscb	A	G	12: 64,518,875 (GRCm39)	S864P	unknown	Het
Glod4	T	A	11: 76,130,376 (GRCm39)	K36*	probably null	Het
Gm6619	G	A	6: 131,467,393 (GRCm39)	R86Q	possibly damaging	Het
Gm7052	T	C	17: 22,258,706 (GRCm39)		probably benign	Het
Gyg1	A	T	3: 20,205,211 (GRCm39)	M119K	probably benign	Het
Ifit2	A	T	19: 34,550,702 (GRCm39)	I81F	probably damaging	Het
Insr	T	C	8: 3,308,682 (GRCm39)	Y118C	probably damaging	Het
Katnip	T	A	7: 125,464,492 (GRCm39)	H1286Q	probably damaging	Het
Kcnh3	T	C	15: 99,137,617 (GRCm39)	S771P	probably benign	Het
Kndc1	C	A	7: 139,500,700 (GRCm39)	H688Q	probably damaging	Het
Mybpc2	A	G	7: 44,165,591 (GRCm39)	C330R	probably damaging	Het
Naa50	A	T	16: 43,976,832 (GRCm39)	N23I	probably damaging	Het
Nt5el	A	T	13: 105,245,868 (GRCm39)	H143L	probably benign	Het
Or55b4	T	A	7: 102,133,685 (GRCm39)	D214V	probably damaging	Het
Or5a1	A	G	19: 12,097,240 (GRCm39)	S279P	probably damaging	Het
Or8b48	T	C	9: 38,493,373 (GRCm39)	S267P	probably benign	Het
Or8c16	T	C	9: 38,131,039 (GRCm39)	S307P	probably benign	Het
Pfkp	A	T	13: 6,653,426 (GRCm39)		probably benign	Het
Phlda2	G	A	7: 143,055,876 (GRCm39)		probably null	Het
Plxnd1	C	A	6: 115,946,906 (GRCm39)	V823L	probably benign	Het
Prpf40a	T	A	2: 53,031,847 (GRCm39)	H794L	probably benign	Het
Ripor2	A	T	13: 24,885,190 (GRCm39)	H436L	probably benign	Het
Rnf138	T	A	18: 21,153,970 (GRCm39)	C159S	possibly damaging	Het
Scn7a	A	T	2: 66,514,582 (GRCm39)	V1064D	probably damaging	Het
Slc12a2	T	A	18: 58,039,092 (GRCm39)	C557*	probably null	Het
Slc1a6	T	C	10: 78,624,831 (GRCm39)	S79P	possibly damaging	Het
Snapin	G	A	3: 90,397,909 (GRCm39)		probably benign	Het
Tdp1	A	T	12: 99,881,704 (GRCm39)		probably benign	Het
Tigar	G	T	6: 127,065,108 (GRCm39)	A180E	probably benign	Het
Trav6-2	A	T	14: 52,905,122 (GRCm39)	T48S	probably benign	Het
Ttn	A	G	2: 76,558,776 (GRCm39)	Y29702H	probably damaging	Het
Ush1c	A	G	7: 45,854,686 (GRCm39)	S689P	probably damaging	Het
Vmn1r40	A	T	6: 89,691,578 (GRCm39)	I132F	probably damaging	Het
Wdr33	C	A	18: 32,039,842 (GRCm39)		probably benign	Het
Ybx2	A	T	11: 69,831,556 (GRCm39)	Q136L	probably damaging	Het
Ypel1	T	A	16: 16,909,076 (GRCm39)	M368L	probably damaging	Het

Other mutations in Vmn1r85

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01520:Vmn1r85	APN	7	12,819,081 (GRCm39)	missense	probably damaging	1.00
IGL01803:Vmn1r85	APN	7	12,818,496 (GRCm39)	missense	probably damaging	0.98
IGL02285:Vmn1r85	APN	7	12,818,711 (GRCm39)	missense	probably damaging	1.00
IGL02852:Vmn1r85	APN	7	12,819,010 (GRCm39)	missense	possibly damaging	0.70
IGL03012:Vmn1r85	APN	7	12,818,692 (GRCm39)	missense	probably benign	0.01
R0391:Vmn1r85	UTSW	7	12,818,515 (GRCm39)	missense	probably benign	0.01
R0655:Vmn1r85	UTSW	7	12,818,650 (GRCm39)	missense	probably damaging	1.00
R1142:Vmn1r85	UTSW	7	12,818,481 (GRCm39)	missense	probably benign	0.01
R1452:Vmn1r85	UTSW	7	12,818,808 (GRCm39)	missense	probably damaging	1.00
R1942:Vmn1r85	UTSW	7	12,818,668 (GRCm39)	missense	possibly damaging	0.83
R3760:Vmn1r85	UTSW	7	12,818,932 (GRCm39)	missense	probably damaging	0.96
R4783:Vmn1r85	UTSW	7	12,818,788 (GRCm39)	missense	probably damaging	1.00
R4785:Vmn1r85	UTSW	7	12,818,788 (GRCm39)	missense	probably damaging	1.00
R5373:Vmn1r85	UTSW	7	12,818,255 (GRCm39)	nonsense	probably null
R6021:Vmn1r85	UTSW	7	12,818,616 (GRCm39)	missense	probably benign	0.00
R6035:Vmn1r85	UTSW	7	12,818,854 (GRCm39)	missense	probably damaging	1.00
R6035:Vmn1r85	UTSW	7	12,818,854 (GRCm39)	missense	probably damaging	1.00
R6834:Vmn1r85	UTSW	7	12,818,571 (GRCm39)	missense	probably damaging	1.00
R7340:Vmn1r85	UTSW	7	12,819,073 (GRCm39)	missense	probably damaging	1.00
R7346:Vmn1r85	UTSW	7	12,818,964 (GRCm39)	missense	probably damaging	0.99
R7836:Vmn1r85	UTSW	7	12,818,698 (GRCm39)	missense	probably benign	0.06
R7896:Vmn1r85	UTSW	7	12,818,448 (GRCm39)	missense	probably benign	0.22
R9090:Vmn1r85	UTSW	7	12,818,942 (GRCm39)	nonsense	probably null
R9271:Vmn1r85	UTSW	7	12,818,942 (GRCm39)	nonsense	probably null
R9354:Vmn1r85	UTSW	7	12,818,725 (GRCm39)	missense	probably damaging	1.00
R9713:Vmn1r85	UTSW	7	12,818,458 (GRCm39)	missense	probably damaging	1.00
R9779:Vmn1r85	UTSW	7	12,818,308 (GRCm39)	missense	probably benign	0.02

Posted On

2013-06-21