Incidental Mutation 'R6394:Zmynd8'
| ID |
515921 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zmynd8
|
| Ensembl Gene |
ENSMUSG00000039671 |
| Gene Name |
zinc finger, MYND-type containing 8 |
| Synonyms |
ZMYND8, RACK7, 1110013E22Rik, 2010005I16Rik, Prkcbp1, 3632413B07Rik |
| MMRRC Submission |
044543-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R6394 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
165626072-165740896 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
C to A
at 165687943 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Stop codon
at position 126
(E126*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136211
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000018050]
[ENSMUST00000088113]
[ENSMUST00000099084]
[ENSMUST00000109262]
[ENSMUST00000109266]
[ENSMUST00000109269]
[ENSMUST00000136842]
[ENSMUST00000153655]
[ENSMUST00000170272]
[ENSMUST00000177633]
|
| AlphaFold |
A2A484 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000018050
AA Change: E131*
|
| SMART Domains |
Protein: ENSMUSP00000018050
Gene: ENSMUSG00000039671
AA Change: E131*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
23 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
56 |
N/A |
INTRINSIC |
|
PHD
|
90 |
131 |
2.23e-11 |
SMART |
|
BROMO
|
147 |
254 |
1.77e-17 |
SMART |
|
Pfam:PWWP
|
275 |
349 |
4e-12 |
PFAM |
|
Pfam:DUF3544
|
412 |
624 |
9.8e-112 |
PFAM |
|
internal_repeat_2
|
640 |
701 |
9.06e-5 |
PROSPERO |
|
low complexity region
|
770 |
805 |
N/A |
INTRINSIC |
|
low complexity region
|
853 |
868 |
N/A |
INTRINSIC |
|
low complexity region
|
875 |
887 |
N/A |
INTRINSIC |
|
coiled coil region
|
916 |
978 |
N/A |
INTRINSIC |
|
Pfam:zf-MYND
|
988 |
1022 |
2.2e-7 |
PFAM |
|
low complexity region
|
1055 |
1075 |
N/A |
INTRINSIC |
|
low complexity region
|
1142 |
1156 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000088113
AA Change: E126*
|
| SMART Domains |
Protein: ENSMUSP00000085436
Gene: ENSMUSG00000039671
AA Change: E126*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
43 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
76 |
N/A |
INTRINSIC |
|
PHD
|
85 |
126 |
2.23e-11 |
SMART |
|
BROMO
|
142 |
249 |
1.77e-17 |
SMART |
|
Pfam:PWWP
|
271 |
346 |
2.7e-11 |
PFAM |
|
Pfam:DUF3544
|
408 |
617 |
2.1e-102 |
PFAM |
|
internal_repeat_2
|
635 |
696 |
4.2e-5 |
PROSPERO |
|
low complexity region
|
765 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
848 |
863 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
882 |
N/A |
INTRINSIC |
|
coiled coil region
|
911 |
973 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1070 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000099084
AA Change: E106*
|
| SMART Domains |
Protein: ENSMUSP00000096683
Gene: ENSMUSG00000039671
AA Change: E106*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
23 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
56 |
N/A |
INTRINSIC |
|
PHD
|
65 |
106 |
2.23e-11 |
SMART |
|
BROMO
|
122 |
229 |
1.77e-17 |
SMART |
|
Pfam:PWWP
|
250 |
324 |
4.1e-12 |
PFAM |
|
Pfam:DUF3544
|
387 |
599 |
1e-111 |
PFAM |
|
internal_repeat_2
|
615 |
676 |
4.95e-5 |
PROSPERO |
|
low complexity region
|
745 |
780 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
844 |
N/A |
INTRINSIC |
|
low complexity region
|
880 |
895 |
N/A |
INTRINSIC |
|
low complexity region
|
902 |
914 |
N/A |
INTRINSIC |
|
coiled coil region
|
943 |
1005 |
N/A |
INTRINSIC |
|
Pfam:zf-MYND
|
1015 |
1049 |
2.3e-7 |
PFAM |
|
low complexity region
|
1082 |
1102 |
N/A |
INTRINSIC |
|
low complexity region
|
1169 |
1183 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000109262
AA Change: E106*
|
| SMART Domains |
Protein: ENSMUSP00000104885
Gene: ENSMUSG00000039671
AA Change: E106*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
23 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
56 |
N/A |
INTRINSIC |
|
PHD
|
65 |
106 |
2.23e-11 |
SMART |
|
BROMO
|
122 |
229 |
1.77e-17 |
SMART |
|
Pfam:PWWP
|
250 |
324 |
1.2e-12 |
PFAM |
|
Pfam:DUF3544
|
387 |
460 |
3.1e-29 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000109266
AA Change: E151*
|
| SMART Domains |
Protein: ENSMUSP00000104889
Gene: ENSMUSG00000039671
AA Change: E151*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
11 |
N/A |
INTRINSIC |
|
low complexity region
|
43 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
76 |
N/A |
INTRINSIC |
|
PHD
|
110 |
151 |
2.23e-11 |
SMART |
|
BROMO
|
167 |
274 |
1.77e-17 |
SMART |
|
Pfam:PWWP
|
295 |
369 |
4.1e-12 |
PFAM |
|
Pfam:DUF3544
|
432 |
644 |
1e-111 |
PFAM |
|
internal_repeat_2
|
660 |
721 |
8.36e-5 |
PROSPERO |
|
low complexity region
|
790 |
825 |
N/A |
INTRINSIC |
|
low complexity region
|
873 |
888 |
N/A |
INTRINSIC |
|
low complexity region
|
895 |
907 |
N/A |
INTRINSIC |
|
coiled coil region
|
936 |
998 |
N/A |
INTRINSIC |
|
Pfam:zf-MYND
|
1008 |
1042 |
2.3e-7 |
PFAM |
|
low complexity region
|
1075 |
1095 |
N/A |
INTRINSIC |
|
low complexity region
|
1162 |
1176 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000109269
AA Change: E135*
|
| SMART Domains |
Protein: ENSMUSP00000104892
Gene: ENSMUSG00000039671
AA Change: E135*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
27 |
38 |
N/A |
INTRINSIC |
|
low complexity region
|
41 |
60 |
N/A |
INTRINSIC |
|
PHD
|
94 |
135 |
2.23e-11 |
SMART |
|
BROMO
|
151 |
258 |
1.77e-17 |
SMART |
|
Pfam:PWWP
|
280 |
355 |
6.6e-11 |
PFAM |
|
Pfam:DUF3544
|
417 |
626 |
2.6e-102 |
PFAM |
|
internal_repeat_2
|
644 |
705 |
6.15e-5 |
PROSPERO |
|
low complexity region
|
774 |
809 |
N/A |
INTRINSIC |
|
low complexity region
|
848 |
873 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
924 |
N/A |
INTRINSIC |
|
low complexity region
|
931 |
943 |
N/A |
INTRINSIC |
|
coiled coil region
|
972 |
1034 |
N/A |
INTRINSIC |
|
low complexity region
|
1111 |
1131 |
N/A |
INTRINSIC |
|
low complexity region
|
1198 |
1212 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000136842
AA Change: E137*
|
| SMART Domains |
Protein: ENSMUSP00000120631
Gene: ENSMUSG00000039671
AA Change: E137*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
54 |
65 |
N/A |
INTRINSIC |
|
low complexity region
|
68 |
87 |
N/A |
INTRINSIC |
|
PHD
|
96 |
137 |
2.23e-11 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000153655
AA Change: E126*
|
| SMART Domains |
Protein: ENSMUSP00000120932
Gene: ENSMUSG00000039671
AA Change: E126*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
4 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
43 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
76 |
N/A |
INTRINSIC |
|
PHD
|
85 |
126 |
2.23e-11 |
SMART |
|
BROMO
|
142 |
249 |
1.77e-17 |
SMART |
|
Pfam:PWWP
|
270 |
344 |
3.5e-12 |
PFAM |
|
Pfam:DUF3544
|
407 |
480 |
6.7e-29 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000170272
AA Change: E106*
|
| SMART Domains |
Protein: ENSMUSP00000128680
Gene: ENSMUSG00000039671
AA Change: E106*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
23 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
56 |
N/A |
INTRINSIC |
|
PHD
|
65 |
106 |
2.23e-11 |
SMART |
|
BROMO
|
122 |
229 |
1.77e-17 |
SMART |
|
Pfam:PWWP
|
250 |
324 |
1.1e-11 |
PFAM |
|
Pfam:DUF3544
|
387 |
599 |
1.9e-111 |
PFAM |
|
internal_repeat_2
|
615 |
676 |
7.92e-5 |
PROSPERO |
|
low complexity region
|
745 |
780 |
N/A |
INTRINSIC |
|
low complexity region
|
828 |
843 |
N/A |
INTRINSIC |
|
low complexity region
|
850 |
862 |
N/A |
INTRINSIC |
|
coiled coil region
|
891 |
953 |
N/A |
INTRINSIC |
|
Pfam:zf-MYND
|
963 |
997 |
1.1e-6 |
PFAM |
|
low complexity region
|
1030 |
1050 |
N/A |
INTRINSIC |
|
low complexity region
|
1117 |
1131 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000177633
AA Change: E126*
|
| SMART Domains |
Protein: ENSMUSP00000136211
Gene: ENSMUSG00000039671
AA Change: E126*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
43 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
76 |
N/A |
INTRINSIC |
|
PHD
|
85 |
126 |
2.23e-11 |
SMART |
|
BROMO
|
142 |
249 |
1.77e-17 |
SMART |
|
Pfam:PWWP
|
270 |
344 |
9.6e-12 |
PFAM |
|
Pfam:DUF3544
|
407 |
619 |
1.8e-111 |
PFAM |
|
internal_repeat_2
|
635 |
696 |
6.45e-5 |
PROSPERO |
|
low complexity region
|
765 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
848 |
863 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
882 |
N/A |
INTRINSIC |
|
coiled coil region
|
911 |
973 |
N/A |
INTRINSIC |
|
Pfam:zf-MYND
|
983 |
1017 |
6.7e-7 |
PFAM |
|
low complexity region
|
1050 |
1070 |
N/A |
INTRINSIC |
|
low complexity region
|
1137 |
1151 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000152682
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000149369
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139202
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139907
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.2%
- 20x: 97.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Akap11 |
A |
T |
14: 78,760,029 (GRCm39) |
|
probably null |
Het |
| Alpi |
T |
A |
1: 87,028,428 (GRCm39) |
Y154F |
possibly damaging |
Het |
| Als2 |
A |
T |
1: 59,206,356 (GRCm39) |
F1635I |
probably damaging |
Het |
| Anxa1 |
C |
T |
19: 20,361,213 (GRCm39) |
V60M |
probably damaging |
Het |
| Atp10b |
A |
G |
11: 43,116,464 (GRCm39) |
Y937C |
probably damaging |
Het |
| Brd4 |
C |
A |
17: 32,443,121 (GRCm39) |
E167* |
probably null |
Het |
| Cacna1h |
G |
A |
17: 25,606,455 (GRCm39) |
T1048I |
probably benign |
Het |
| Ccdc113 |
A |
G |
8: 96,283,820 (GRCm39) |
D298G |
probably benign |
Het |
| Cfap100 |
T |
A |
6: 90,394,605 (GRCm39) |
N74I |
possibly damaging |
Het |
| Chd8 |
A |
T |
14: 52,440,042 (GRCm39) |
H4Q |
possibly damaging |
Het |
| Clcn1 |
A |
G |
6: 42,284,524 (GRCm39) |
T621A |
possibly damaging |
Het |
| Clcn1 |
A |
G |
6: 42,290,172 (GRCm39) |
T843A |
possibly damaging |
Het |
| Clcn3 |
C |
T |
8: 61,394,325 (GRCm39) |
R68Q |
probably damaging |
Het |
| Dcaf13 |
T |
A |
15: 39,007,132 (GRCm39) |
N355K |
probably benign |
Het |
| Dnah6 |
A |
T |
6: 73,132,401 (GRCm39) |
C1100* |
probably null |
Het |
| Dync2h1 |
A |
T |
9: 7,168,331 (GRCm39) |
V428E |
probably damaging |
Het |
| E230025N22Rik |
T |
C |
18: 36,819,839 (GRCm39) |
E317G |
probably damaging |
Het |
| Eml2 |
G |
A |
7: 18,935,088 (GRCm39) |
V432I |
probably damaging |
Het |
| Evc2 |
C |
A |
5: 37,535,619 (GRCm39) |
D431E |
probably damaging |
Het |
| Gcm2 |
T |
G |
13: 41,263,373 (GRCm39) |
T20P |
probably damaging |
Het |
| Gdf9 |
A |
G |
11: 53,327,524 (GRCm39) |
Y160C |
probably damaging |
Het |
| Gm8220 |
A |
G |
14: 44,523,134 (GRCm39) |
|
probably benign |
Het |
| Gpalpp1 |
A |
T |
14: 76,344,852 (GRCm39) |
S44T |
possibly damaging |
Het |
| Grip2 |
T |
C |
6: 91,764,182 (GRCm39) |
Y134C |
probably damaging |
Het |
| Hephl1 |
A |
G |
9: 14,985,397 (GRCm39) |
F753S |
probably benign |
Het |
| Herc1 |
A |
G |
9: 66,302,341 (GRCm39) |
T727A |
probably damaging |
Het |
| Herc2 |
A |
G |
7: 55,865,729 (GRCm39) |
E4232G |
probably damaging |
Het |
| Ifi207 |
A |
G |
1: 173,556,581 (GRCm39) |
L726P |
probably benign |
Het |
| Itga11 |
T |
A |
9: 62,642,548 (GRCm39) |
|
probably null |
Het |
| Jrkl |
A |
C |
9: 13,245,495 (GRCm39) |
Y55* |
probably null |
Het |
| Kif13a |
C |
T |
13: 46,905,931 (GRCm39) |
V671M |
possibly damaging |
Het |
| Kif18b |
A |
G |
11: 102,805,236 (GRCm39) |
V303A |
probably damaging |
Het |
| Klhl29 |
A |
T |
12: 5,144,830 (GRCm39) |
C423* |
probably null |
Het |
| Klhl29 |
T |
C |
12: 5,187,720 (GRCm39) |
S215G |
probably benign |
Het |
| Lamp5 |
A |
G |
2: 135,902,929 (GRCm39) |
D216G |
possibly damaging |
Het |
| Leo1 |
T |
A |
9: 75,352,752 (GRCm39) |
D98E |
probably benign |
Het |
| Map3k3 |
T |
C |
11: 106,039,709 (GRCm39) |
V283A |
probably benign |
Het |
| Med12l |
A |
G |
3: 59,142,508 (GRCm39) |
K902E |
probably damaging |
Het |
| Mmp1b |
C |
A |
9: 7,386,316 (GRCm39) |
D202Y |
probably benign |
Het |
| Muc21 |
A |
T |
17: 35,931,058 (GRCm39) |
|
probably benign |
Het |
| Onecut3 |
A |
G |
10: 80,331,847 (GRCm39) |
I336V |
probably damaging |
Het |
| Oprl1 |
C |
T |
2: 181,360,795 (GRCm39) |
R257C |
probably damaging |
Het |
| Or10g9 |
T |
C |
9: 39,912,001 (GRCm39) |
Q174R |
probably benign |
Het |
| Or10h1 |
G |
A |
17: 33,418,487 (GRCm39) |
G155D |
probably damaging |
Het |
| Or4c11b |
C |
T |
2: 88,625,296 (GRCm39) |
T190I |
probably benign |
Het |
| Or56b1 |
T |
A |
7: 104,284,909 (GRCm39) |
N9K |
possibly damaging |
Het |
| Or56b1 |
T |
C |
7: 104,285,234 (GRCm39) |
S118P |
possibly damaging |
Het |
| Or5p64 |
C |
T |
7: 107,854,970 (GRCm39) |
R125H |
possibly damaging |
Het |
| Or6c69 |
G |
T |
10: 129,747,789 (GRCm39) |
D119E |
probably damaging |
Het |
| Osbpl6 |
T |
C |
2: 76,386,298 (GRCm39) |
V207A |
probably benign |
Het |
| Pde3a |
A |
T |
6: 141,433,237 (GRCm39) |
H756L |
probably damaging |
Het |
| Peg10 |
T |
TCCG |
6: 4,756,451 (GRCm39) |
|
probably benign |
Het |
| Phyh |
A |
G |
2: 4,940,814 (GRCm39) |
D238G |
probably benign |
Het |
| Pnliprp2 |
T |
A |
19: 58,750,030 (GRCm39) |
N92K |
probably benign |
Het |
| Pole3 |
T |
C |
4: 62,442,263 (GRCm39) |
|
probably benign |
Het |
| Ppm1d |
T |
C |
11: 85,230,498 (GRCm39) |
V372A |
probably benign |
Het |
| Prpf40a |
A |
T |
2: 53,034,890 (GRCm39) |
I766N |
probably damaging |
Het |
| Prr5 |
T |
A |
15: 84,583,925 (GRCm39) |
V175E |
probably damaging |
Het |
| Prss59 |
A |
T |
6: 40,898,726 (GRCm39) |
L174* |
probably null |
Het |
| Ptprq |
T |
A |
10: 107,478,804 (GRCm39) |
K1280* |
probably null |
Het |
| Rbp2 |
T |
A |
9: 98,389,873 (GRCm39) |
V95E |
possibly damaging |
Het |
| Rictor |
T |
C |
15: 6,798,790 (GRCm39) |
F346L |
possibly damaging |
Het |
| Rsf1 |
ATGGCG |
ATGGCGACGGTGGCG |
7: 97,229,111 (GRCm39) |
|
probably benign |
Homo |
| Scn10a |
T |
A |
9: 119,490,386 (GRCm39) |
I519F |
probably benign |
Het |
| Setd5 |
T |
G |
6: 113,092,505 (GRCm39) |
V295G |
probably damaging |
Het |
| Shcbp1 |
A |
T |
8: 4,786,176 (GRCm39) |
M642K |
probably damaging |
Het |
| Slc13a3 |
C |
T |
2: 165,276,017 (GRCm39) |
G243E |
probably damaging |
Het |
| Smg9 |
T |
C |
7: 24,121,732 (GRCm39) |
Y498H |
probably damaging |
Het |
| Sox5 |
T |
C |
6: 143,987,039 (GRCm39) |
D175G |
probably damaging |
Het |
| Stard7 |
A |
G |
2: 127,126,161 (GRCm39) |
D71G |
probably damaging |
Het |
| Stxbp5 |
A |
T |
10: 9,774,975 (GRCm39) |
Y59* |
probably null |
Het |
| Supt6 |
G |
A |
11: 78,121,891 (GRCm39) |
R254C |
probably damaging |
Het |
| Syne2 |
C |
T |
12: 76,037,269 (GRCm39) |
T3817I |
probably benign |
Het |
| Tas2r124 |
T |
A |
6: 132,732,039 (GRCm39) |
I116N |
probably damaging |
Het |
| Trim9 |
T |
A |
12: 70,301,987 (GRCm39) |
E550D |
possibly damaging |
Het |
| Vmn2r50 |
A |
G |
7: 9,774,253 (GRCm39) |
S548P |
probably damaging |
Het |
| Zswim9 |
A |
T |
7: 12,994,889 (GRCm39) |
S422R |
probably damaging |
Het |
|
| Other mutations in Zmynd8 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01288:Zmynd8
|
APN |
2 |
165,654,734 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01311:Zmynd8
|
APN |
2 |
165,647,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02317:Zmynd8
|
APN |
2 |
165,662,492 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02548:Zmynd8
|
APN |
2 |
165,675,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02798:Zmynd8
|
APN |
2 |
165,694,070 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL02933:Zmynd8
|
APN |
2 |
165,670,238 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
cain
|
UTSW |
2 |
165,699,973 (GRCm39) |
critical splice donor site |
probably null |
|
|
F5770:Zmynd8
|
UTSW |
2 |
165,654,314 (GRCm39) |
nonsense |
probably null |
|
|
I1329:Zmynd8
|
UTSW |
2 |
165,670,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0031:Zmynd8
|
UTSW |
2 |
165,662,618 (GRCm39) |
splice site |
probably benign |
|
|
R0267:Zmynd8
|
UTSW |
2 |
165,670,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0608:Zmynd8
|
UTSW |
2 |
165,629,078 (GRCm39) |
splice site |
probably null |
|
|
R1663:Zmynd8
|
UTSW |
2 |
165,649,805 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2212:Zmynd8
|
UTSW |
2 |
165,657,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3412:Zmynd8
|
UTSW |
2 |
165,657,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3413:Zmynd8
|
UTSW |
2 |
165,657,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3749:Zmynd8
|
UTSW |
2 |
165,647,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3820:Zmynd8
|
UTSW |
2 |
165,657,381 (GRCm39) |
nonsense |
probably null |
|
|
R3836:Zmynd8
|
UTSW |
2 |
165,700,019 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3957:Zmynd8
|
UTSW |
2 |
165,654,395 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4379:Zmynd8
|
UTSW |
2 |
165,649,858 (GRCm39) |
splice site |
probably null |
|
|
R4526:Zmynd8
|
UTSW |
2 |
165,649,527 (GRCm39) |
intron |
probably benign |
|
|
R4739:Zmynd8
|
UTSW |
2 |
165,647,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4838:Zmynd8
|
UTSW |
2 |
165,681,954 (GRCm39) |
nonsense |
probably null |
|
|
R4932:Zmynd8
|
UTSW |
2 |
165,676,871 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4933:Zmynd8
|
UTSW |
2 |
165,676,871 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4997:Zmynd8
|
UTSW |
2 |
165,634,736 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5652:Zmynd8
|
UTSW |
2 |
165,649,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5741:Zmynd8
|
UTSW |
2 |
165,681,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6008:Zmynd8
|
UTSW |
2 |
165,684,707 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6242:Zmynd8
|
UTSW |
2 |
165,740,867 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6332:Zmynd8
|
UTSW |
2 |
165,680,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6772:Zmynd8
|
UTSW |
2 |
165,649,521 (GRCm39) |
missense |
probably benign |
0.35 |
|
R6970:Zmynd8
|
UTSW |
2 |
165,717,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6986:Zmynd8
|
UTSW |
2 |
165,675,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7229:Zmynd8
|
UTSW |
2 |
165,699,973 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7266:Zmynd8
|
UTSW |
2 |
165,649,492 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R7296:Zmynd8
|
UTSW |
2 |
165,681,929 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7642:Zmynd8
|
UTSW |
2 |
165,654,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Zmynd8
|
UTSW |
2 |
165,684,751 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7821:Zmynd8
|
UTSW |
2 |
165,723,000 (GRCm39) |
intron |
probably benign |
|
|
R8135:Zmynd8
|
UTSW |
2 |
165,654,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8828:Zmynd8
|
UTSW |
2 |
165,654,466 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9128:Zmynd8
|
UTSW |
2 |
165,700,058 (GRCm39) |
start codon destroyed |
probably null |
|
|
R9200:Zmynd8
|
UTSW |
2 |
165,682,005 (GRCm39) |
missense |
probably benign |
|
|
R9345:Zmynd8
|
UTSW |
2 |
165,654,668 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9478:Zmynd8
|
UTSW |
2 |
165,649,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9626:Zmynd8
|
UTSW |
2 |
165,654,268 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9649:Zmynd8
|
UTSW |
2 |
165,680,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9759:Zmynd8
|
UTSW |
2 |
165,680,746 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
V7580:Zmynd8
|
UTSW |
2 |
165,654,314 (GRCm39) |
nonsense |
probably null |
|
|
V7581:Zmynd8
|
UTSW |
2 |
165,654,314 (GRCm39) |
nonsense |
probably null |
|
|
V7583:Zmynd8
|
UTSW |
2 |
165,654,314 (GRCm39) |
nonsense |
probably null |
|
|
Z1088:Zmynd8
|
UTSW |
2 |
165,670,091 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Zmynd8
|
UTSW |
2 |
165,670,108 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCTTTCCAAGAGCTGCCC -3'
(R):5'- GTCCGTTTTACTATATGAAGCAGCC -3'
Sequencing Primer
(F):5'- TTCCAAGAGCTGCCCCACTG -3'
(R):5'- TTTACTATATGAAGCAGCCACTCAC -3'
|
| Posted On |
2018-05-04 |
Incidental Mutation