Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01134:Cyp2g1'

51630

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cyp2g1

Ensembl Gene

ENSMUSG00000049685

Gene Name

cytochrome P450, family 2, subfamily g, polypeptide 1

Synonyms

Accession Numbers

Is this an essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01134

Quality Score

Status

Chromosome

Chromosomal Location

26808892-26821205 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 26809831 bp

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Serine at position 110 (N110S)

Ref Sequence

ENSEMBL: ENSMUSP00000047150 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000040944]

Predicted Effect

probably benign
Transcript: ENSMUST00000040944
AA Change: N110S

PolyPhen 2 Score 0.048 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000047150
Gene: ENSMUSG00000049685
AA Change: N110S

Domain	Start	End	E-Value	Type
low complexity region	12	23	N/A	INTRINSIC
Pfam:p450	34	491	4e-150	PFAM

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for disruptions in this gene display an essentially normal phenotype. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110038F14Rik	G	A	15: 76,950,275	V124I	probably damaging	Het
Acaca	T	G	11: 84,251,279	H637Q	probably benign	Het
Aen	G	A	7: 78,907,302	M299I	probably damaging	Het
Akap6	C	A	12: 52,937,217	A848E	probably damaging	Het
Cxxc4	A	G	3: 134,240,659	I334V	probably null	Het
Cyp2b13	T	A	7: 26,081,700	I179N	probably damaging	Het
Cyp2d40	C	A	15: 82,760,901	A183S	unknown	Het
F5	A	T	1: 164,191,979	R674S	possibly damaging	Het
Fnip2	G	T	3: 79,512,503	Y155*	probably null	Het
Fut9	G	T	4: 25,620,446	Q123K	probably benign	Het
Gda	A	G	19: 21,417,065	S143P	probably damaging	Het
Gpr162	T	C	6: 124,858,857		probably null	Het
Hsf2bp	A	G	17: 31,987,404	L251S	probably damaging	Het
Hsh2d	A	T	8: 72,193,531	D24V	probably damaging	Het
Htr1f	T	A	16: 64,926,138	T264S	probably benign	Het
Med12l	G	A	3: 59,042,275	E151K	possibly damaging	Het
Mgat3	C	A	15: 80,212,176	N401K	probably benign	Het
Mmp27	T	G	9: 7,573,297	M130R	probably benign	Het
Mroh2b	T	A	15: 4,915,152	S412T	probably benign	Het
Mrps9	A	G	1: 42,903,397	I338M	probably damaging	Het
Mtmr4	C	T	11: 87,604,067	T395M	probably damaging	Het
Nlrp9b	A	G	7: 20,023,187	I116M	probably benign	Het
Nqo1	T	C	8: 107,388,955	D230G	probably benign	Het
Pcnx2	C	T	8: 125,863,150	V795I	probably benign	Het
Pde8a	G	A	7: 81,319,078	R449Q	possibly damaging	Het
Scn9a	A	G	2: 66,504,968	Y1226H	probably damaging	Het
Sema3e	A	G	5: 14,252,770	R770G	probably damaging	Het
Smr2	T	C	5: 88,108,519	S19P	probably damaging	Het
Trank1	T	C	9: 111,391,781	S2529P	probably benign	Het
Uspl1	T	A	5: 149,204,293	F367L	probably damaging	Het
Vps41	A	G	13: 18,866,150	S838G	probably benign	Het
Ythdf2	A	T	4: 132,205,478	F124I	probably damaging	Het

Other mutations in Cyp2g1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01137:Cyp2g1	APN	7	26814259	missense	possibly damaging	0.87
IGL02052:Cyp2g1	APN	7	26814294	splice site	probably benign
IGL02338:Cyp2g1	APN	7	26814804	splice site	probably benign
IGL02452:Cyp2g1	APN	7	26811446	missense	probably benign	0.28
IGL02523:Cyp2g1	APN	7	26819187	missense	probably damaging	1.00
IGL03165:Cyp2g1	APN	7	26809776	missense	possibly damaging	0.94
IGL03230:Cyp2g1	APN	7	26819403	missense	probably damaging	1.00
PIT4472001:Cyp2g1	UTSW	7	26814194	missense	probably benign	0.28
R0106:Cyp2g1	UTSW	7	26814182	missense	probably damaging	1.00
R0106:Cyp2g1	UTSW	7	26814182	missense	probably damaging	1.00
R0380:Cyp2g1	UTSW	7	26814295	splice site	probably benign
R0697:Cyp2g1	UTSW	7	26814727	nonsense	probably null
R0830:Cyp2g1	UTSW	7	26814791	missense	probably benign	0.00
R1660:Cyp2g1	UTSW	7	26809682	critical splice acceptor site	probably null
R2093:Cyp2g1	UTSW	7	26819433	missense	probably benign	0.35
R2131:Cyp2g1	UTSW	7	26820710	missense	probably damaging	0.99
R4606:Cyp2g1	UTSW	7	26814154	missense	possibly damaging	0.80
R5030:Cyp2g1	UTSW	7	26820801	missense	probably benign	0.06
R5574:Cyp2g1	UTSW	7	26820740	missense	possibly damaging	0.81
R5877:Cyp2g1	UTSW	7	26816640	missense	possibly damaging	0.80
R6745:Cyp2g1	UTSW	7	26814179	missense	probably damaging	1.00
R7040:Cyp2g1	UTSW	7	26820759	missense	probably damaging	0.99
R7223:Cyp2g1	UTSW	7	26814632	missense	probably damaging	0.98
X0067:Cyp2g1	UTSW	7	26820762	missense	possibly damaging	0.70

Posted On

2013-06-21