Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01147:Vmn1r158'

51665

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r158

Ensembl Gene

ENSMUSG00000094700

Gene Name

vomeronasal 1 receptor 158

Synonyms

Gm16455

Accession Numbers

Is this an essential gene?

Possibly non essential (E-score: 0.426) question?

Stock #

IGL01147

Quality Score

Status

Chromosome

Chromosomal Location

22789859-22790782 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 22790779 bp

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 2 (S2P)

Ref Sequence

ENSEMBL: ENSMUSP00000133990 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000174643]

Predicted Effect

probably benign
Transcript: ENSMUST00000174643
AA Change: S2P

PolyPhen 2 Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)

SMART Domains

Protein: ENSMUSP00000133990
Gene: ENSMUSG00000094700
AA Change: S2P

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	298	2.9e-15	PFAM
Pfam:7tm_1	39	290	5.5e-9	PFAM
Pfam:V1R	41	298	3.2e-17	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 36 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc3	A	G	11: 94,343,785		probably benign	Het
Aen	G	A	7: 78,907,302	M299I	probably damaging	Het
Cdh1	C	A	8: 106,660,884	T472K	probably damaging	Het
Cfap206	C	T	4: 34,721,562	S162N	probably damaging	Het
Cfap57	A	T	4: 118,589,001	V688E	probably damaging	Het
Cfp	G	A	X: 20,928,742	R155C	probably damaging	Het
Chst7	T	C	X: 20,060,752	I346T	probably damaging	Het
Crybg2	G	A	4: 134,089,264		probably null	Het
Ctsc	T	A	7: 88,302,271	V242D	possibly damaging	Het
Cyp27b1	C	T	10: 127,050,386	T312I	possibly damaging	Het
D6Wsu163e	A	G	6: 126,944,852	D80G	possibly damaging	Het
Enpp3	G	T	10: 24,774,907	T777K	probably damaging	Het
H2-M1	T	A	17: 36,671,307	H134L	possibly damaging	Het
Heatr1	T	C	13: 12,437,912	S2105P	probably damaging	Het
Herc2	T	C	7: 56,156,949	S2388P	probably benign	Het
Igkv6-23	A	G	6: 70,260,938		probably benign	Het
Il1rapl2	C	T	X: 138,220,576		probably benign	Het
Itpka	T	C	2: 119,742,773	L132P	probably benign	Het
Jak3	T	C	8: 71,683,403	S616P	probably benign	Het
Kcnj11	T	C	7: 46,098,769	K377E	probably benign	Het
Map4k3	A	T	17: 80,636,718		probably null	Het
Parp1	T	C	1: 180,589,580	I643T	probably damaging	Het
Phf3	T	C	1: 30,804,169	D1903G	probably damaging	Het
Picalm	G	T	7: 90,177,592	S416I	probably benign	Het
Pkn2	T	C	3: 142,829,009	N285S	probably benign	Het
Sh3gl2	A	C	4: 85,347,196		probably benign	Het
Smpd1	C	A	7: 105,555,736	T274K	probably damaging	Het
Snap91	G	A	9: 86,798,558	T424M	probably benign	Het
Sox13	T	A	1: 133,393,135	T46S	probably benign	Het
Syne1	G	A	10: 5,052,691	Q8075*	probably null	Het
Trio	T	C	15: 27,881,320	E555G	probably damaging	Het
Upf3b	T	C	X: 37,096,933	E298G	probably damaging	Het
Vmn1r6	T	A	6: 57,002,641	L74H	probably damaging	Het
Vwa2	T	C	19: 56,901,634	S224P	probably damaging	Het
Wbp1l	T	A	19: 46,644,369	V36E	probably damaging	Het
Zfp367	A	G	13: 64,135,439	S300P	probably damaging	Het

Other mutations in Vmn1r158

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R1173:Vmn1r158	UTSW	7	22790445	missense	probably benign	0.19
R1574:Vmn1r158	UTSW	7	22790347	missense	probably damaging	1.00
R1574:Vmn1r158	UTSW	7	22790347	missense	probably damaging	1.00
R1725:Vmn1r158	UTSW	7	22790647	missense	probably benign	0.08
R1777:Vmn1r158	UTSW	7	22790430	missense	probably damaging	1.00
R1813:Vmn1r158	UTSW	7	22790718	missense	probably damaging	1.00
R1896:Vmn1r158	UTSW	7	22790718	missense	probably damaging	1.00
R2077:Vmn1r158	UTSW	7	22790390	missense	probably benign	0.03
R3749:Vmn1r158	UTSW	7	22790214	missense	probably damaging	1.00
R4872:Vmn1r158	UTSW	7	22790754	missense	possibly damaging	0.94
R5238:Vmn1r158	UTSW	7	22790374	missense	probably benign
R6500:Vmn1r158	UTSW	7	22790653	missense	possibly damaging	0.89
R6511:Vmn1r158	UTSW	7	22790691	missense	probably benign	0.00
R6581:Vmn1r158	UTSW	7	22790040	missense	possibly damaging	0.69
R6751:Vmn1r158	UTSW	7	22789881	missense	probably damaging	0.96
R7168:Vmn1r158	UTSW	7	22790676	missense	possibly damaging	0.82
R7337:Vmn1r158	UTSW	7	22790224	missense	probably benign	0.00
R7747:Vmn1r158	UTSW	7	22790300	missense	probably benign	0.15
R7902:Vmn1r158	UTSW	7	22790008	missense	possibly damaging	0.67
R8328:Vmn1r158	UTSW	7	22790062	missense	probably damaging	1.00
R8400:Vmn1r158	UTSW	7	22789880	nonsense	probably null
Z1177:Vmn1r158	UTSW	7	22790458	missense	possibly damaging	0.46

Posted On

2013-06-21