Incidental Mutation 'R6478:Umodl1'
| ID |
516941 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| MMRRC Submission |
044610-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6478 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
31173614-31229684 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 31178129 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 35
(Y35C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000110202
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066554
AA Change: Y35C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
AA Change: Y35C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066981
AA Change: Y35C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
AA Change: Y35C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000114555
AA Change: Y35C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
AA Change: Y35C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.7134 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 97.8%
- 20x: 93.3%
|
| Validation Efficiency |
95% (75/79) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aatk |
T |
A |
11: 119,901,817 (GRCm39) |
S803C |
probably benign |
Het |
| Abcc9 |
C |
T |
6: 142,625,034 (GRCm39) |
A454T |
probably damaging |
Het |
| Abr |
T |
C |
11: 76,343,158 (GRCm39) |
E565G |
probably damaging |
Het |
| Adam33 |
C |
A |
2: 130,893,266 (GRCm39) |
R753L |
probably benign |
Het |
| Adgre1 |
A |
G |
17: 57,708,955 (GRCm39) |
T49A |
possibly damaging |
Het |
| Ankra2 |
A |
T |
13: 98,404,950 (GRCm39) |
H153L |
probably damaging |
Het |
| Ankrd26 |
T |
G |
6: 118,488,599 (GRCm39) |
E1353D |
probably benign |
Het |
| Ankrd52 |
T |
G |
10: 128,215,200 (GRCm39) |
|
probably null |
Het |
| Arhgef10l |
T |
A |
4: 140,270,068 (GRCm39) |
T619S |
possibly damaging |
Het |
| Armh4 |
A |
G |
14: 50,010,789 (GRCm39) |
V306A |
possibly damaging |
Het |
| Asgr1 |
T |
C |
11: 69,947,720 (GRCm39) |
V130A |
possibly damaging |
Het |
| Atg10 |
C |
A |
13: 91,085,466 (GRCm39) |
C161F |
probably damaging |
Het |
| Atm |
A |
T |
9: 53,401,554 (GRCm39) |
N1438K |
probably damaging |
Het |
| BC107364 |
T |
A |
3: 96,343,322 (GRCm39) |
|
probably null |
Het |
| Bcar3 |
G |
T |
3: 122,220,225 (GRCm39) |
A41S |
probably benign |
Het |
| Btbd6 |
A |
G |
12: 112,940,932 (GRCm39) |
|
probably benign |
Het |
| Cchcr1 |
A |
G |
17: 35,835,600 (GRCm39) |
T318A |
possibly damaging |
Het |
| Celsr1 |
A |
T |
15: 85,809,719 (GRCm39) |
I2221N |
probably damaging |
Het |
| Cept1 |
C |
T |
3: 106,440,761 (GRCm39) |
W48* |
probably null |
Het |
| Cfap161 |
T |
A |
7: 83,442,484 (GRCm39) |
I85L |
probably benign |
Het |
| Clasp1 |
A |
T |
1: 118,439,910 (GRCm39) |
R640* |
probably null |
Het |
| Col5a1 |
T |
A |
2: 27,842,448 (GRCm39) |
I441N |
unknown |
Het |
| Col9a1 |
C |
A |
1: 24,224,486 (GRCm39) |
L223I |
unknown |
Het |
| Dnah2 |
T |
C |
11: 69,406,836 (GRCm39) |
D223G |
probably benign |
Het |
| Dnah8 |
G |
A |
17: 30,967,542 (GRCm39) |
D2585N |
probably benign |
Het |
| Dpy19l1 |
A |
T |
9: 24,361,992 (GRCm39) |
M129K |
possibly damaging |
Het |
| Ecpas |
A |
T |
4: 58,810,785 (GRCm39) |
I1524N |
probably damaging |
Het |
| Fcgbpl1 |
C |
G |
7: 27,854,798 (GRCm39) |
P1808R |
probably damaging |
Het |
| Fcrl1 |
C |
A |
3: 87,296,946 (GRCm39) |
H318Q |
probably benign |
Het |
| Fer1l5 |
A |
G |
1: 36,441,612 (GRCm39) |
N609S |
probably damaging |
Het |
| Fkbp4 |
C |
T |
6: 128,410,194 (GRCm39) |
E256K |
probably damaging |
Het |
| Fsip2 |
A |
G |
2: 82,820,430 (GRCm39) |
T5388A |
possibly damaging |
Het |
| Glrx |
G |
A |
13: 75,995,418 (GRCm39) |
|
probably null |
Het |
| Gm7356 |
A |
T |
17: 14,221,726 (GRCm39) |
M101K |
probably damaging |
Het |
| Gstp2 |
A |
T |
19: 4,090,499 (GRCm39) |
I162N |
probably benign |
Het |
| Hectd3 |
A |
C |
4: 116,856,783 (GRCm39) |
K443N |
probably damaging |
Het |
| Hmcn1 |
T |
A |
1: 150,540,535 (GRCm39) |
R2925W |
probably damaging |
Het |
| Hspa1a |
G |
T |
17: 35,189,282 (GRCm39) |
N540K |
probably damaging |
Het |
| Ints6 |
A |
T |
14: 62,938,235 (GRCm39) |
M649K |
probably benign |
Het |
| Katnb1 |
T |
C |
8: 95,822,084 (GRCm39) |
V270A |
possibly damaging |
Het |
| Kctd3 |
A |
G |
1: 188,704,561 (GRCm39) |
S737P |
probably benign |
Het |
| Klra10 |
T |
C |
6: 130,249,507 (GRCm39) |
|
probably null |
Het |
| Lmtk3 |
A |
G |
7: 45,448,013 (GRCm39) |
D1353G |
unknown |
Het |
| Lrrk1 |
A |
G |
7: 65,912,481 (GRCm39) |
V1693A |
probably damaging |
Het |
| Mpnd |
A |
T |
17: 56,316,575 (GRCm39) |
I85F |
probably damaging |
Het |
| Myo3b |
A |
G |
2: 70,179,304 (GRCm39) |
T1173A |
probably benign |
Het |
| Myof |
G |
A |
19: 37,892,279 (GRCm39) |
P1158L |
probably damaging |
Het |
| Naip2 |
A |
C |
13: 100,298,549 (GRCm39) |
S496A |
probably benign |
Het |
| Ncor2 |
A |
G |
5: 125,187,069 (GRCm39) |
|
probably benign |
Het |
| Npepps |
C |
T |
11: 97,149,099 (GRCm39) |
|
probably null |
Het |
| Opn5 |
T |
A |
17: 42,891,640 (GRCm39) |
I266F |
probably benign |
Het |
| Or4a74 |
T |
G |
2: 89,439,790 (GRCm39) |
I219L |
probably damaging |
Het |
| P2rx4 |
A |
G |
5: 122,845,763 (GRCm39) |
D16G |
probably damaging |
Het |
| Padi2 |
G |
T |
4: 140,644,948 (GRCm39) |
V61L |
probably benign |
Het |
| Pkd1l1 |
G |
A |
11: 8,813,911 (GRCm39) |
T1480I |
probably benign |
Het |
| Plcb1 |
T |
C |
2: 135,177,371 (GRCm39) |
S568P |
probably damaging |
Het |
| Rassf10 |
A |
G |
7: 112,554,914 (GRCm39) |
E505G |
probably damaging |
Het |
| Rcan2 |
A |
G |
17: 44,147,225 (GRCm39) |
E21G |
probably benign |
Het |
| Rhob |
G |
T |
12: 8,549,585 (GRCm39) |
C16* |
probably null |
Het |
| Ryr3 |
T |
C |
2: 112,490,413 (GRCm39) |
N3807S |
probably damaging |
Het |
| Sass6 |
T |
A |
3: 116,415,046 (GRCm39) |
N519K |
probably benign |
Het |
| Slco1a8 |
A |
T |
6: 141,939,368 (GRCm39) |
N208K |
possibly damaging |
Het |
| Smad9 |
A |
T |
3: 54,689,864 (GRCm39) |
D28V |
probably damaging |
Het |
| Spmip8 |
A |
T |
8: 96,047,894 (GRCm39) |
|
probably null |
Het |
| Tex14 |
G |
T |
11: 87,405,199 (GRCm39) |
G704C |
probably benign |
Het |
| Tmc3 |
A |
G |
7: 83,271,524 (GRCm39) |
N892S |
probably benign |
Het |
| Tnfaip2 |
T |
A |
12: 111,412,097 (GRCm39) |
L166Q |
probably damaging |
Het |
| Triml2 |
A |
G |
8: 43,638,165 (GRCm39) |
|
probably null |
Het |
| Trio |
A |
G |
15: 27,856,193 (GRCm39) |
V666A |
probably benign |
Het |
| Tshz2 |
G |
T |
2: 169,726,584 (GRCm39) |
L393F |
probably damaging |
Het |
| Ttn |
T |
G |
2: 76,672,115 (GRCm39) |
|
probably benign |
Het |
| Tubb5 |
A |
G |
17: 36,146,734 (GRCm39) |
Y159H |
probably damaging |
Het |
| Utp4 |
T |
C |
8: 107,631,078 (GRCm39) |
|
probably null |
Het |
| Vmn1r60 |
A |
T |
7: 5,547,864 (GRCm39) |
C79S |
probably damaging |
Het |
| Wnt5b |
T |
C |
6: 119,410,751 (GRCm39) |
T230A |
probably damaging |
Het |
| Zfp618 |
A |
T |
4: 63,050,943 (GRCm39) |
I575F |
probably damaging |
Het |
| Zmym6 |
G |
T |
4: 127,017,176 (GRCm39) |
V894L |
possibly damaging |
Het |
| Zpbp |
T |
C |
11: 11,412,318 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,227,724 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
31,215,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
31,215,233 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
31,217,800 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
31,215,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
31,201,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
31,192,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
31,206,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
31,205,091 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
31,187,415 (GRCm39) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
31,217,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
31,208,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
31,205,473 (GRCm39) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
31,215,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
31,203,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0831:Umodl1
|
UTSW |
17 |
31,215,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1078:Umodl1
|
UTSW |
17 |
31,178,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,221,772 (GRCm39) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
31,205,478 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1459:Umodl1
|
UTSW |
17 |
31,201,232 (GRCm39) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
31,178,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
31,206,942 (GRCm39) |
missense |
probably benign |
|
|
R1757:Umodl1
|
UTSW |
17 |
31,227,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1781:Umodl1
|
UTSW |
17 |
31,187,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Umodl1
|
UTSW |
17 |
31,201,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
31,211,128 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
31,211,062 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
31,211,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
31,208,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,221,837 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
31,203,763 (GRCm39) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
31,178,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
31,207,039 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4684:Umodl1
|
UTSW |
17 |
31,217,088 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4769:Umodl1
|
UTSW |
17 |
31,202,976 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4887:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4888:Umodl1
|
UTSW |
17 |
31,218,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
31,205,055 (GRCm39) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
31,205,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
31,203,066 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
31,199,333 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
31,201,263 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
31,213,761 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
31,215,256 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,221,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
31,201,325 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
31,205,121 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6702:Umodl1
|
UTSW |
17 |
31,205,273 (GRCm39) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
31,218,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
31,201,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
31,201,318 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7219:Umodl1
|
UTSW |
17 |
31,201,236 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7231:Umodl1
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7234:Umodl1
|
UTSW |
17 |
31,205,595 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7392:Umodl1
|
UTSW |
17 |
31,201,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7401:Umodl1
|
UTSW |
17 |
31,217,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
31,173,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
31,205,430 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
31,178,125 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
31,192,666 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
31,205,361 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
31,192,770 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
31,190,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
31,203,806 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
31,202,958 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
31,192,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
31,178,147 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9270:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9341:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
31,215,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9569:Umodl1
|
UTSW |
17 |
31,217,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9615:Umodl1
|
UTSW |
17 |
31,217,152 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
31,178,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACACTAGGACTGTTGGGCTG -3'
(R):5'- GTGACTCACACAGAACGCAGTAG -3'
Sequencing Primer
(F):5'- GGTTCTAGGGCCCATTCAACAGTAG -3'
(R):5'- ACAGCAGTCGGTCACATTCCTG -3'
|
| Posted On |
2018-05-21 |
Incidental Mutation