Incidental Mutation 'R6463:Cadps2'
| ID |
517681 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cadps2
|
| Ensembl Gene |
ENSMUSG00000017978 |
| Gene Name |
Ca2+-dependent activator protein for secretion 2 |
| Synonyms |
Caps2, cpd2, A230044C21Rik |
| MMRRC Submission |
045324-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6463 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
23262773-23839421 bp(-) (GRCm38) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
A to T
at 23323334 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Stop codon
at position 1016
(L1016*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125972
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000018122]
[ENSMUST00000069074]
[ENSMUST00000115358]
[ENSMUST00000115361]
[ENSMUST00000125350]
[ENSMUST00000142913]
[ENSMUST00000163871]
[ENSMUST00000166458]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000018122
AA Change: L1045*
|
| SMART Domains |
Protein: ENSMUSP00000018122
Gene: ENSMUSG00000017978
AA Change: L1045*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
65 |
N/A |
INTRINSIC |
|
low complexity region
|
114 |
126 |
N/A |
INTRINSIC |
|
coiled coil region
|
265 |
285 |
N/A |
INTRINSIC |
|
C2
|
369 |
467 |
1.51e-1 |
SMART |
|
PH
|
492 |
596 |
2.94e-11 |
SMART |
|
DUF1041
|
801 |
902 |
1.14e-52 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000069074
AA Change: L1038*
|
| SMART Domains |
Protein: ENSMUSP00000064876
Gene: ENSMUSG00000017978
AA Change: L1038*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
65 |
N/A |
INTRINSIC |
|
low complexity region
|
114 |
126 |
N/A |
INTRINSIC |
|
coiled coil region
|
265 |
285 |
N/A |
INTRINSIC |
|
C2
|
369 |
467 |
1.51e-1 |
SMART |
|
PH
|
492 |
596 |
2.94e-11 |
SMART |
|
DUF1041
|
801 |
895 |
5.54e-51 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000115358
AA Change: L1005*
|
| SMART Domains |
Protein: ENSMUSP00000111015
Gene: ENSMUSG00000017978
AA Change: L1005*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
65 |
N/A |
INTRINSIC |
|
low complexity region
|
114 |
126 |
N/A |
INTRINSIC |
|
coiled coil region
|
265 |
285 |
N/A |
INTRINSIC |
|
C2
|
369 |
467 |
1.51e-1 |
SMART |
|
PH
|
492 |
596 |
2.94e-11 |
SMART |
|
DUF1041
|
801 |
902 |
1.14e-52 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000115361
AA Change: L995*
|
| SMART Domains |
Protein: ENSMUSP00000111018
Gene: ENSMUSG00000017978
AA Change: L995*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
65 |
N/A |
INTRINSIC |
|
low complexity region
|
114 |
126 |
N/A |
INTRINSIC |
|
coiled coil region
|
265 |
285 |
N/A |
INTRINSIC |
|
C2
|
369 |
467 |
1.51e-1 |
SMART |
|
PH
|
492 |
596 |
2.94e-11 |
SMART |
|
DUF1041
|
801 |
892 |
1.9e-49 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000125350
AA Change: L640*
|
| SMART Domains |
Protein: ENSMUSP00000115866
Gene: ENSMUSG00000017978
AA Change: L640*
| Domain | Start | End | E-Value | Type |
|---|
|
C2
|
14 |
112 |
1.51e-1 |
SMART |
|
PH
|
137 |
241 |
2.94e-11 |
SMART |
|
DUF1041
|
446 |
537 |
1.9e-49 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000142913
AA Change: L1016*
|
| SMART Domains |
Protein: ENSMUSP00000138167
Gene: ENSMUSG00000017978
AA Change: L1016*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
22 |
39 |
N/A |
INTRINSIC |
|
low complexity region
|
85 |
97 |
N/A |
INTRINSIC |
|
coiled coil region
|
236 |
256 |
N/A |
INTRINSIC |
|
C2
|
340 |
438 |
1.51e-1 |
SMART |
|
PH
|
463 |
567 |
2.94e-11 |
SMART |
|
DUF1041
|
772 |
873 |
1.14e-52 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156986
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000163871
AA Change: L1045*
|
| SMART Domains |
Protein: ENSMUSP00000128905
Gene: ENSMUSG00000017978
AA Change: L1045*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
65 |
N/A |
INTRINSIC |
|
low complexity region
|
114 |
126 |
N/A |
INTRINSIC |
|
coiled coil region
|
265 |
285 |
N/A |
INTRINSIC |
|
C2
|
369 |
467 |
1.51e-1 |
SMART |
|
PH
|
492 |
596 |
2.94e-11 |
SMART |
|
DUF1041
|
801 |
902 |
7.2e-50 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000166458
AA Change: L1016*
|
| SMART Domains |
Protein: ENSMUSP00000125972
Gene: ENSMUSG00000017978
AA Change: L1016*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
85 |
97 |
N/A |
INTRINSIC |
|
coiled coil region
|
236 |
256 |
N/A |
INTRINSIC |
|
C2
|
340 |
438 |
1.51e-1 |
SMART |
|
PH
|
463 |
567 |
2.94e-11 |
SMART |
|
DUF1041
|
772 |
873 |
1.05e-51 |
SMART |
|
| Meta Mutation Damage Score |
0.9752 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 97.8%
- 20x: 92.4%
|
| Validation Efficiency |
100% (51/51) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
PHENOTYPE: Mice homozygous for a null allele exhibit defects in cerebellum, Purkinje cell and interneuron morphology, paired-pulse facilitation, and behaviors including emotional behavior, vestibuoocular reflex, circadium and sleep patterns, social investigation and nurturing behavior. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 48 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700009N14Rik |
A |
T |
4: 39,450,938 (GRCm38) |
H48L |
probably damaging |
Het |
| Aifm3 |
A |
G |
16: 17,500,789 (GRCm38) |
I185V |
probably benign |
Het |
| Asb7 |
A |
T |
7: 66,660,236 (GRCm38) |
D77E |
probably damaging |
Het |
| Cacna1i |
T |
C |
15: 80,355,758 (GRCm38) |
I336T |
probably damaging |
Het |
| Cep63 |
C |
A |
9: 102,596,155 (GRCm38) |
M504I |
probably benign |
Het |
| Chpf2 |
G |
T |
5: 24,589,526 (GRCm38) |
L231F |
probably damaging |
Het |
| Cnot10 |
T |
C |
9: 114,625,902 (GRCm38) |
Y221C |
probably damaging |
Het |
| Col3a1 |
G |
A |
1: 45,342,205 (GRCm38) |
|
probably benign |
Het |
| Csl |
T |
C |
10: 99,759,098 (GRCm38) |
D35G |
probably damaging |
Het |
| Csmd3 |
T |
C |
15: 47,676,479 (GRCm38) |
Y2286C |
probably damaging |
Het |
| Dbt |
A |
G |
3: 116,539,760 (GRCm38) |
E293G |
possibly damaging |
Het |
| Ddx31 |
T |
A |
2: 28,847,513 (GRCm38) |
|
probably null |
Het |
| Dnm1 |
T |
C |
2: 32,309,591 (GRCm38) |
|
probably benign |
Het |
| Elfn1 |
A |
G |
5: 139,972,285 (GRCm38) |
Y348C |
probably damaging |
Het |
| Enpp5 |
G |
A |
17: 44,085,264 (GRCm38) |
G356S |
probably damaging |
Het |
| Epha5 |
T |
A |
5: 84,106,710 (GRCm38) |
I657F |
probably damaging |
Het |
| Fbp1 |
A |
G |
13: 62,865,010 (GRCm38) |
F123S |
possibly damaging |
Het |
| Hkdc1 |
T |
C |
10: 62,393,702 (GRCm38) |
N732S |
probably damaging |
Het |
| Itfg1 |
A |
G |
8: 85,736,151 (GRCm38) |
S448P |
probably benign |
Het |
| Itprid1 |
A |
G |
6: 55,968,678 (GRCm38) |
R795G |
probably benign |
Het |
| Izumo2 |
A |
G |
7: 44,709,074 (GRCm38) |
K84R |
probably benign |
Het |
| Kbtbd3 |
A |
G |
9: 4,316,921 (GRCm38) |
Y24C |
probably benign |
Het |
| Kif1b |
T |
C |
4: 149,192,596 (GRCm38) |
M1337V |
probably benign |
Het |
| Mdn1 |
T |
C |
4: 32,773,308 (GRCm38) |
L5489P |
probably damaging |
Het |
| Mettl2 |
G |
A |
11: 105,132,581 (GRCm38) |
|
probably null |
Het |
| Mtr |
T |
C |
13: 12,216,866 (GRCm38) |
T651A |
probably benign |
Het |
| Naglu |
A |
G |
11: 101,077,351 (GRCm38) |
|
probably null |
Het |
| Nkx6-1 |
G |
T |
5: 101,659,476 (GRCm38) |
H347N |
probably damaging |
Het |
| Ntpcr |
A |
G |
8: 125,736,104 (GRCm38) |
E20G |
probably benign |
Het |
| Oas2 |
T |
C |
5: 120,734,981 (GRCm38) |
R670G |
probably null |
Het |
| Or10h1 |
G |
A |
17: 33,199,638 (GRCm38) |
V197I |
probably benign |
Het |
| Or2ag16 |
C |
G |
7: 106,752,801 (GRCm38) |
E196Q |
probably benign |
Het |
| Or4p8 |
T |
C |
2: 88,897,118 (GRCm38) |
I160V |
probably benign |
Het |
| Phldb2 |
A |
C |
16: 45,774,993 (GRCm38) |
V902G |
probably benign |
Het |
| Rdh7 |
T |
C |
10: 127,885,781 (GRCm38) |
R209G |
probably benign |
Het |
| Slc13a3 |
A |
C |
2: 165,445,653 (GRCm38) |
L127R |
probably damaging |
Het |
| Slc6a20b |
T |
A |
9: 123,604,949 (GRCm38) |
I275F |
possibly damaging |
Het |
| St3gal1 |
A |
G |
15: 67,111,346 (GRCm38) |
V187A |
possibly damaging |
Het |
| Tmx4 |
T |
C |
2: 134,620,639 (GRCm38) |
Y124C |
probably damaging |
Het |
| Trh |
A |
T |
6: 92,242,843 (GRCm38) |
M164K |
possibly damaging |
Het |
| Trhr |
A |
G |
15: 44,197,585 (GRCm38) |
N167S |
probably benign |
Het |
| Ttll7 |
G |
A |
3: 146,931,582 (GRCm38) |
R490Q |
possibly damaging |
Het |
| Uck1 |
T |
C |
2: 32,258,655 (GRCm38) |
N100S |
probably benign |
Het |
| Ucp3 |
A |
T |
7: 100,480,269 (GRCm38) |
T104S |
probably benign |
Het |
| Vmn2r28 |
T |
A |
7: 5,486,436 (GRCm38) |
H468L |
probably benign |
Het |
| Xaf1 |
G |
A |
11: 72,308,638 (GRCm38) |
R67H |
probably benign |
Het |
| Ypel4 |
T |
C |
2: 84,736,743 (GRCm38) |
|
probably benign |
Het |
| Zfp687 |
A |
G |
3: 95,010,784 (GRCm38) |
I559T |
probably damaging |
Het |
|
| Other mutations in Cadps2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01014:Cadps2
|
APN |
6 |
23,496,874 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
IGL01105:Cadps2
|
APN |
6 |
23,321,700 (GRCm38) |
splice site |
probably benign |
|
|
IGL01317:Cadps2
|
APN |
6 |
23,314,173 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
IGL01409:Cadps2
|
APN |
6 |
23,587,441 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01477:Cadps2
|
APN |
6 |
23,263,673 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01620:Cadps2
|
APN |
6 |
23,587,462 (GRCm38) |
missense |
probably benign |
0.19 |
|
IGL01674:Cadps2
|
APN |
6 |
23,355,852 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01675:Cadps2
|
APN |
6 |
23,382,905 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01895:Cadps2
|
APN |
6 |
23,427,275 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02095:Cadps2
|
APN |
6 |
23,427,310 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02200:Cadps2
|
APN |
6 |
23,385,528 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02380:Cadps2
|
APN |
6 |
23,287,732 (GRCm38) |
missense |
probably benign |
0.11 |
|
IGL02680:Cadps2
|
APN |
6 |
23,838,896 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02814:Cadps2
|
APN |
6 |
23,321,707 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02940:Cadps2
|
APN |
6 |
23,496,809 (GRCm38) |
missense |
probably benign |
0.08 |
|
IGL03061:Cadps2
|
APN |
6 |
23,287,660 (GRCm38) |
splice site |
probably null |
|
|
IGL03233:Cadps2
|
APN |
6 |
23,263,601 (GRCm38) |
missense |
probably benign |
0.10 |
|
R0193:Cadps2
|
UTSW |
6 |
23,599,440 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0389:Cadps2
|
UTSW |
6 |
23,321,782 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R0571:Cadps2
|
UTSW |
6 |
23,583,412 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0595:Cadps2
|
UTSW |
6 |
23,321,704 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0620:Cadps2
|
UTSW |
6 |
23,583,396 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0723:Cadps2
|
UTSW |
6 |
23,287,698 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0831:Cadps2
|
UTSW |
6 |
23,321,740 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R0836:Cadps2
|
UTSW |
6 |
23,328,776 (GRCm38) |
splice site |
probably benign |
|
|
R0942:Cadps2
|
UTSW |
6 |
23,263,562 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1099:Cadps2
|
UTSW |
6 |
23,599,479 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1120:Cadps2
|
UTSW |
6 |
23,838,794 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1216:Cadps2
|
UTSW |
6 |
23,583,473 (GRCm38) |
splice site |
probably benign |
|
|
R1575:Cadps2
|
UTSW |
6 |
23,429,218 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1780:Cadps2
|
UTSW |
6 |
23,320,932 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1924:Cadps2
|
UTSW |
6 |
23,688,858 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1944:Cadps2
|
UTSW |
6 |
23,599,480 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1956:Cadps2
|
UTSW |
6 |
23,287,686 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1986:Cadps2
|
UTSW |
6 |
23,323,380 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2045:Cadps2
|
UTSW |
6 |
23,839,122 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R2146:Cadps2
|
UTSW |
6 |
23,838,999 (GRCm38) |
intron |
probably benign |
|
|
R2147:Cadps2
|
UTSW |
6 |
23,838,999 (GRCm38) |
intron |
probably benign |
|
|
R2148:Cadps2
|
UTSW |
6 |
23,838,999 (GRCm38) |
intron |
probably benign |
|
|
R2150:Cadps2
|
UTSW |
6 |
23,838,999 (GRCm38) |
intron |
probably benign |
|
|
R2219:Cadps2
|
UTSW |
6 |
23,410,832 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2264:Cadps2
|
UTSW |
6 |
23,323,340 (GRCm38) |
missense |
probably benign |
0.15 |
|
R2338:Cadps2
|
UTSW |
6 |
23,838,978 (GRCm38) |
splice site |
probably benign |
|
|
R3861:Cadps2
|
UTSW |
6 |
23,355,861 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3898:Cadps2
|
UTSW |
6 |
23,528,126 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3982:Cadps2
|
UTSW |
6 |
23,263,531 (GRCm38) |
utr 3 prime |
probably benign |
|
|
R4213:Cadps2
|
UTSW |
6 |
23,599,463 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4384:Cadps2
|
UTSW |
6 |
23,412,988 (GRCm38) |
missense |
probably benign |
0.18 |
|
R4432:Cadps2
|
UTSW |
6 |
23,626,738 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4609:Cadps2
|
UTSW |
6 |
23,587,579 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4806:Cadps2
|
UTSW |
6 |
23,688,860 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4977:Cadps2
|
UTSW |
6 |
23,599,479 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5174:Cadps2
|
UTSW |
6 |
23,287,743 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5267:Cadps2
|
UTSW |
6 |
23,626,668 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R5389:Cadps2
|
UTSW |
6 |
23,329,104 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5737:Cadps2
|
UTSW |
6 |
23,328,805 (GRCm38) |
missense |
probably benign |
0.28 |
|
R6074:Cadps2
|
UTSW |
6 |
23,626,671 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6254:Cadps2
|
UTSW |
6 |
23,329,163 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R6323:Cadps2
|
UTSW |
6 |
23,263,578 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6907:Cadps2
|
UTSW |
6 |
23,599,506 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6940:Cadps2
|
UTSW |
6 |
23,302,492 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6964:Cadps2
|
UTSW |
6 |
23,583,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7079:Cadps2
|
UTSW |
6 |
23,323,409 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7139:Cadps2
|
UTSW |
6 |
23,410,889 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7156:Cadps2
|
UTSW |
6 |
23,688,956 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7184:Cadps2
|
UTSW |
6 |
23,583,429 (GRCm38) |
missense |
probably benign |
0.18 |
|
R7325:Cadps2
|
UTSW |
6 |
23,409,935 (GRCm38) |
missense |
unknown |
|
|
R7526:Cadps2
|
UTSW |
6 |
23,496,851 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7546:Cadps2
|
UTSW |
6 |
23,626,608 (GRCm38) |
missense |
probably benign |
0.15 |
|
R7772:Cadps2
|
UTSW |
6 |
23,390,446 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7870:Cadps2
|
UTSW |
6 |
23,263,642 (GRCm38) |
missense |
probably benign |
0.14 |
|
R8040:Cadps2
|
UTSW |
6 |
23,412,943 (GRCm38) |
splice site |
probably benign |
|
|
R8048:Cadps2
|
UTSW |
6 |
23,838,863 (GRCm38) |
missense |
probably benign |
0.14 |
|
R8082:Cadps2
|
UTSW |
6 |
23,323,314 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8100:Cadps2
|
UTSW |
6 |
23,838,809 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8115:Cadps2
|
UTSW |
6 |
23,328,898 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8497:Cadps2
|
UTSW |
6 |
23,355,919 (GRCm38) |
missense |
probably benign |
0.27 |
|
R8768:Cadps2
|
UTSW |
6 |
23,382,939 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8783:Cadps2
|
UTSW |
6 |
23,302,304 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R8804:Cadps2
|
UTSW |
6 |
23,496,806 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8832:Cadps2
|
UTSW |
6 |
23,587,537 (GRCm38) |
missense |
possibly damaging |
0.52 |
|
R8848:Cadps2
|
UTSW |
6 |
23,344,257 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8854:Cadps2
|
UTSW |
6 |
23,385,508 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8896:Cadps2
|
UTSW |
6 |
23,410,877 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8910:Cadps2
|
UTSW |
6 |
23,344,224 (GRCm38) |
missense |
probably benign |
0.11 |
|
R8921:Cadps2
|
UTSW |
6 |
23,302,301 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9228:Cadps2
|
UTSW |
6 |
23,688,928 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9297:Cadps2
|
UTSW |
6 |
23,496,888 (GRCm38) |
missense |
probably benign |
|
|
R9318:Cadps2
|
UTSW |
6 |
23,496,888 (GRCm38) |
missense |
probably benign |
|
|
R9348:Cadps2
|
UTSW |
6 |
23,344,263 (GRCm38) |
missense |
probably benign |
0.20 |
|
R9447:Cadps2
|
UTSW |
6 |
23,323,298 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9484:Cadps2
|
UTSW |
6 |
23,626,647 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9492:Cadps2
|
UTSW |
6 |
23,427,239 (GRCm38) |
missense |
probably benign |
|
|
R9630:Cadps2
|
UTSW |
6 |
23,587,572 (GRCm38) |
missense |
probably benign |
0.08 |
|
R9729:Cadps2
|
UTSW |
6 |
23,382,983 (GRCm38) |
missense |
probably benign |
0.28 |
|
Z1176:Cadps2
|
UTSW |
6 |
23,321,801 (GRCm38) |
missense |
probably benign |
0.24 |
|
Z1177:Cadps2
|
UTSW |
6 |
23,838,818 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Cadps2
|
UTSW |
6 |
23,626,695 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Cadps2
|
UTSW |
6 |
23,385,478 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAATTCCATGGTTCCCCAGG -3'
(R):5'- CATTATCACAGAAGGAAAACCAGTG -3'
Sequencing Primer
(F):5'- ATTCCATGGTTCCCCAGGATTAAGG -3'
(R):5'- GGATGGATGTGTGTGGCCC -3'
|
| Posted On |
2018-05-21 |
Incidental Mutation