Incidental Mutation 'IGL01105:Slc35f3'
ID51773
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Slc35f3
Ensembl Gene ENSMUSG00000057060
Gene Namesolute carrier family 35, member F3
SynonymsB230375D17Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.172) question?
Stock #IGL01105
Quality Score
Status
Chromosome8
Chromosomal Location126298558-126395482 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to A at 126298814 bp
ZygosityHeterozygous
Amino Acid Change Proline to Glutamine at position 10 (P10Q)
Ref Sequence ENSEMBL: ENSMUSP00000104390 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000108759]
Predicted Effect probably damaging
Transcript: ENSMUST00000108759
AA Change: P10Q

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000104390
Gene: ENSMUSG00000057060
AA Change: P10Q

DomainStartEndE-ValueType
low complexity region 25 49 N/A INTRINSIC
Pfam:EamA 67 223 3.2e-7 PFAM
Pfam:SLC35F 145 374 3.2e-6 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ace T A 11: 105,972,059 V302E probably damaging Het
Ahcy T C 2: 155,067,361 D86G probably benign Het
Antxr2 G T 5: 98,004,943 probably benign Het
Cadps2 A G 6: 23,321,700 probably benign Het
Cdhr4 C T 9: 107,995,861 probably benign Het
Cdkn2c C T 4: 109,661,626 V44I probably damaging Het
Chodl T C 16: 78,941,263 Y40H probably damaging Het
Heatr3 A G 8: 88,161,893 D391G probably benign Het
Hephl1 T C 9: 15,089,024 T311A possibly damaging Het
Itpr1 G A 6: 108,381,333 S620N probably benign Het
Kank1 T A 19: 25,424,316 S1096T possibly damaging Het
Kank3 G A 17: 33,817,401 G81E probably damaging Het
Krtap9-5 A G 11: 99,948,633 I53M unknown Het
Limk2 G A 11: 3,355,475 probably benign Het
Lrig2 G A 3: 104,464,168 R382* probably null Het
Mamdc2 T A 19: 23,331,002 D512V probably benign Het
March1 A T 8: 66,418,877 T353S possibly damaging Het
Mrc2 A G 11: 105,328,741 D312G probably damaging Het
Myh9 C T 15: 77,781,478 M627I probably benign Het
Nipa2 A T 7: 55,933,445 I184N probably damaging Het
Npy1r A G 8: 66,704,776 K246R probably benign Het
Pank4 C T 4: 154,972,465 probably benign Het
Pcdh12 T A 18: 38,275,347 E1035D probably damaging Het
Pias2 T A 18: 77,133,156 D362E probably damaging Het
Pkd1l3 G T 8: 109,662,241 V1872L possibly damaging Het
Postn T G 3: 54,362,710 I70S probably damaging Het
Ppef2 A G 5: 92,249,196 S107P possibly damaging Het
Prl3c1 T C 13: 27,202,425 V131A probably benign Het
Qsox2 A G 2: 26,209,685 V609A probably benign Het
Rhebl1 C A 15: 98,878,498 E139D probably benign Het
Ryr3 A G 2: 112,751,805 S2848P probably damaging Het
Scd2 T A 19: 44,298,058 I109N probably benign Het
Sim1 A G 10: 50,981,534 H460R probably damaging Het
Slf1 T C 13: 77,100,912 probably benign Het
Stk10 G T 11: 32,577,740 V163L probably benign Het
Tssk6 A G 8: 69,902,812 T169A probably benign Het
Usp28 T A 9: 49,010,250 V256E probably damaging Het
Vmn2r77 A T 7: 86,811,664 I733F probably damaging Het
Other mutations in Slc35f3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00687:Slc35f3 APN 8 126382164 missense probably benign 0.02
IGL00956:Slc35f3 APN 8 126382224 missense probably damaging 1.00
IGL01710:Slc35f3 APN 8 126389161 missense probably benign 0.00
IGL01771:Slc35f3 APN 8 126389212 missense probably benign 0.00
IGL02254:Slc35f3 APN 8 126389123 missense probably damaging 1.00
IGL02610:Slc35f3 APN 8 126321217 missense probably damaging 1.00
R1666:Slc35f3 UTSW 8 126389221 missense probably damaging 0.98
R2510:Slc35f3 UTSW 8 126298706 start gained probably benign
R2520:Slc35f3 UTSW 8 126394573 missense possibly damaging 0.81
R3807:Slc35f3 UTSW 8 126389239 missense probably damaging 1.00
R4644:Slc35f3 UTSW 8 126321070 missense possibly damaging 0.87
R4675:Slc35f3 UTSW 8 126321196 nonsense probably null
R4976:Slc35f3 UTSW 8 126389281 splice site probably null
R5037:Slc35f3 UTSW 8 126389272 missense probably damaging 0.99
R5225:Slc35f3 UTSW 8 126391107 missense probably damaging 0.98
R5259:Slc35f3 UTSW 8 126389133 missense probably damaging 1.00
R5856:Slc35f3 UTSW 8 126321080 missense probably benign 0.07
R5925:Slc35f3 UTSW 8 126389207 missense probably benign 0.24
R6254:Slc35f3 UTSW 8 126321094 missense possibly damaging 0.96
R6748:Slc35f3 UTSW 8 126394638 nonsense probably null
R6785:Slc35f3 UTSW 8 126394459 missense probably benign 0.02
R7002:Slc35f3 UTSW 8 126389034 critical splice acceptor site unknown
R7291:Slc35f3 UTSW 8 126394558 missense probably benign 0.02
R7411:Slc35f3 UTSW 8 126389038 critical splice acceptor site unknown
R7456:Slc35f3 UTSW 8 126389040 critical splice acceptor site unknown
X0067:Slc35f3 UTSW 8 126382323 missense probably damaging 0.99
Posted On2013-06-21