Mutagenetix > Incidental Mutation

Incidental Mutation 'R6416:Dst'

517908

Institutional Source

Beutler Lab

Gene Symbol

Dst

Ensembl Gene

ENSMUSG00000026131

Gene Name

dystonin

Synonyms

BPAG1-n, ah, athetoid, bullous pemphigoid antigen 1, A830042E19Rik, Macf2, nmf339, Bpag1, nmf203, bullous pemphigoid antigen 1, BPAG1, Bpag, 2310001O04Rik

MMRRC Submission

044558-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.269) question?

Stock #

R6416 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

33908225-34308661 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 34116128 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Methionine at position 85 (K85M)

Ref Sequence

ENSEMBL: ENSMUSP00000110756 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000097785] [ENSMUST00000097786] [ENSMUST00000115104] [ENSMUST00000182314] [ENSMUST00000182697] [ENSMUST00000183034] [ENSMUST00000187486]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000097785
AA Change: K85M

PolyPhen 2 Score 0.969 (Sensitivity: 0.77; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000095392
Gene: ENSMUSG00000026131
AA Change: K85M

Domain	Start	End	E-Value	Type
CH	37	136	1.62e-28	SMART
CH	153	250	3.72e-19	SMART
PDB:2ODU\|A	261	479	1e-42	PDB
low complexity region	520	545	N/A	INTRINSIC
SPEC	602	699	8.64e-9	SMART
SPEC	702	802	2.94e-11	SMART
Blast:SPEC	809	973	4e-73	BLAST
coiled coil region	1095	1132	N/A	INTRINSIC
Blast:SPEC	1176	1285	6e-63	BLAST
SPEC	1292	1421	4.11e0	SMART
SPEC	1439	1538	4.66e0	SMART
PLEC	1537	1581	9.05e-3	SMART
PLEC	1582	1619	2.7e0	SMART
PLEC	1657	1694	2.23e0	SMART
PLEC	1695	1732	4.25e1	SMART
PLEC	1735	1770	1.39e2	SMART
PLEC	1771	1808	7.4e-8	SMART
PLEC	1811	1846	5.8e-1	SMART
PLEC	1847	1884	2.71e1	SMART
PLEC	1886	1922	4.66e0	SMART
low complexity region	2294	2307	N/A	INTRINSIC
low complexity region	2366	2381	N/A	INTRINSIC
low complexity region	2477	2491	N/A	INTRINSIC
low complexity region	2566	2593	N/A	INTRINSIC
low complexity region	2661	2675	N/A	INTRINSIC
low complexity region	2793	2799	N/A	INTRINSIC
low complexity region	2839	2847	N/A	INTRINSIC
low complexity region	3046	3057	N/A	INTRINSIC
low complexity region	3294	3314	N/A	INTRINSIC
SPEC	3321	3427	5.36e-1	SMART
low complexity region	3515	3527	N/A	INTRINSIC
low complexity region	3548	3558	N/A	INTRINSIC
SPEC	3569	3678	2.19e-1	SMART
internal_repeat_7	3771	3811	5.09e-5	PROSPERO
SPEC	3852	3971	1.75e-9	SMART
SPEC	3978	4084	3.7e-8	SMART
SPEC	4091	4190	4.56e-8	SMART
SPEC	4200	4299	3.78e0	SMART
low complexity region	4372	4388	N/A	INTRINSIC
SPEC	4447	4552	1.98e-8	SMART
SPEC	4559	4663	3.62e-11	SMART
SPEC	4673	4773	1.65e-5	SMART
SPEC	4780	4882	7.75e-11	SMART
SPEC	4889	4989	2.3e-4	SMART
SPEC	4999	5098	3.01e0	SMART
SPEC	5105	5208	2.74e-2	SMART
SPEC	5215	5319	2.46e-4	SMART
SPEC	5326	5428	1.27e-15	SMART
SPEC	5435	5537	1.54e-14	SMART
SPEC	5544	5646	8.07e-2	SMART
SPEC	5653	5755	3.67e-12	SMART
SPEC	5762	5863	1.97e-12	SMART
SPEC	5870	5976	4.19e-7	SMART
SPEC	5983	6085	2.06e-15	SMART
SPEC	6092	6195	2.89e-10	SMART
SPEC	6202	6304	2.61e-26	SMART
SPEC	6311	6413	5.31e-18	SMART
SPEC	6420	6522	1.25e-14	SMART
SPEC	6529	6632	9.1e-17	SMART
SPEC	6639	6740	9.3e-23	SMART
SPEC	6747	6849	5.43e-15	SMART
SPEC	6859	6989	1.5e-8	SMART
EFh	7023	7051	4.12e-3	SMART
EFh	7059	7087	1.25e-2	SMART
GAS2	7098	7176	3.08e-51	SMART
low complexity region	7224	7242	N/A	INTRINSIC
low complexity region	7252	7264	N/A	INTRINSIC
low complexity region	7313	7336	N/A	INTRINSIC
PDB:3GJO\|H	7364	7393	9e-10	PDB

Predicted Effect

probably damaging
Transcript: ENSMUST00000097786
AA Change: K85M

PolyPhen 2 Score 0.969 (Sensitivity: 0.77; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000095393
Gene: ENSMUSG00000026131
AA Change: K85M

Domain	Start	End	E-Value	Type
CH	37	136	1.62e-28	SMART
CH	153	250	3.72e-19	SMART
PDB:2ODU\|A	261	479	6e-43	PDB
low complexity region	520	545	N/A	INTRINSIC
SPEC	602	699	8.64e-9	SMART
SPEC	702	802	2.94e-11	SMART
Blast:SPEC	809	973	2e-73	BLAST
coiled coil region	1095	1132	N/A	INTRINSIC
Blast:SPEC	1176	1285	2e-62	BLAST
SPEC	1292	1421	4.11e0	SMART
SPEC	1439	1538	4.66e0	SMART
SPEC	1555	1664	2.19e-1	SMART
internal_repeat_6	1757	1797	1.18e-5	PROSPERO
SPEC	1838	1957	1.75e-9	SMART
SPEC	1964	2070	3.7e-8	SMART
SPEC	2077	2176	4.56e-8	SMART
SPEC	2186	2285	3.78e0	SMART
low complexity region	2358	2374	N/A	INTRINSIC
SPEC	2433	2538	1.98e-8	SMART
SPEC	2545	2649	3.62e-11	SMART
SPEC	2659	2759	1.65e-5	SMART
SPEC	2766	2868	7.75e-11	SMART
SPEC	2875	2975	2.3e-4	SMART
SPEC	2985	3084	3.01e0	SMART
SPEC	3091	3194	2.74e-2	SMART
SPEC	3201	3305	2.46e-4	SMART
SPEC	3312	3414	1.27e-15	SMART
SPEC	3421	3523	1.54e-14	SMART
SPEC	3530	3632	8.07e-2	SMART
SPEC	3639	3741	3.67e-12	SMART
SPEC	3748	3849	1.97e-12	SMART
SPEC	3856	3962	4.19e-7	SMART
SPEC	3969	4071	2.06e-15	SMART
SPEC	4078	4181	2.89e-10	SMART
SPEC	4188	4290	2.61e-26	SMART
SPEC	4297	4399	5.31e-18	SMART
SPEC	4406	4508	1.25e-14	SMART
SPEC	4515	4618	9.1e-17	SMART
SPEC	4625	4726	9.3e-23	SMART
SPEC	4733	4835	5.43e-15	SMART
SPEC	4845	4975	1.5e-8	SMART
EFh	5009	5037	4.12e-3	SMART
EFh	5045	5073	1.25e-2	SMART
GAS2	5084	5162	3.08e-51	SMART
low complexity region	5210	5228	N/A	INTRINSIC
low complexity region	5238	5250	N/A	INTRINSIC
low complexity region	5299	5322	N/A	INTRINSIC
PDB:3GJO\|H	5350	5379	1e-9	PDB

Predicted Effect

probably damaging
Transcript: ENSMUST00000115104
AA Change: K85M

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000110756
Gene: ENSMUSG00000026131
AA Change: K85M

Domain	Start	End	E-Value	Type
CH	37	136	1.62e-28	SMART
CH	153	250	3.72e-19	SMART
PDB:2ODU\|A	261	479	1e-42	PDB
low complexity region	520	545	N/A	INTRINSIC
SPEC	602	699	8.64e-9	SMART
SPEC	702	802	2.94e-11	SMART
Blast:SPEC	809	973	4e-73	BLAST
coiled coil region	1095	1132	N/A	INTRINSIC
Blast:SPEC	1176	1285	6e-63	BLAST
SPEC	1292	1421	4.11e0	SMART
SPEC	1439	1538	4.66e0	SMART
PLEC	1537	1581	9.05e-3	SMART
PLEC	1582	1619	2.7e0	SMART
PLEC	1657	1694	2.23e0	SMART
PLEC	1695	1732	4.25e1	SMART
PLEC	1735	1770	1.39e2	SMART
PLEC	1771	1808	7.4e-8	SMART
PLEC	1811	1846	5.8e-1	SMART
PLEC	1847	1884	2.71e1	SMART
PLEC	1886	1922	4.66e0	SMART
low complexity region	2294	2307	N/A	INTRINSIC
low complexity region	2366	2381	N/A	INTRINSIC
low complexity region	2477	2491	N/A	INTRINSIC
low complexity region	2566	2593	N/A	INTRINSIC
low complexity region	2661	2675	N/A	INTRINSIC
low complexity region	2793	2799	N/A	INTRINSIC
low complexity region	2839	2847	N/A	INTRINSIC
low complexity region	3046	3057	N/A	INTRINSIC
low complexity region	3294	3314	N/A	INTRINSIC
SPEC	3321	3427	5.36e-1	SMART
low complexity region	3515	3527	N/A	INTRINSIC
low complexity region	3548	3558	N/A	INTRINSIC
SPEC	3569	3678	2.19e-1	SMART
internal_repeat_7	3771	3811	5.08e-5	PROSPERO
SPEC	3852	3971	1.75e-9	SMART
SPEC	3978	4084	3.7e-8	SMART
SPEC	4091	4190	4.56e-8	SMART
SPEC	4200	4299	3.78e0	SMART
low complexity region	4372	4388	N/A	INTRINSIC
SPEC	4447	4552	1.98e-8	SMART
SPEC	4559	4663	3.62e-11	SMART
SPEC	4673	4773	1.65e-5	SMART
SPEC	4780	4882	7.75e-11	SMART
SPEC	4889	4989	2.3e-4	SMART
SPEC	4999	5098	3.01e0	SMART
SPEC	5105	5208	2.74e-2	SMART
SPEC	5215	5319	2.46e-4	SMART
SPEC	5326	5428	1.27e-15	SMART
SPEC	5435	5537	1.54e-14	SMART
SPEC	5544	5646	8.07e-2	SMART
SPEC	5653	5755	3.67e-12	SMART
SPEC	5762	5863	1.97e-12	SMART
SPEC	5870	5976	4.19e-7	SMART
SPEC	5983	6085	2.06e-15	SMART
SPEC	6092	6195	2.89e-10	SMART
SPEC	6202	6304	2.61e-26	SMART
SPEC	6311	6413	5.31e-18	SMART
SPEC	6420	6522	1.25e-14	SMART
SPEC	6529	6632	9.1e-17	SMART
SPEC	6639	6740	9.3e-23	SMART
SPEC	6747	6849	5.43e-15	SMART
SPEC	6859	6989	1.5e-8	SMART
EFh	7023	7051	4.12e-3	SMART
EFh	7059	7087	1.25e-2	SMART
GAS2	7098	7176	3.85e-52	SMART
low complexity region	7200	7218	N/A	INTRINSIC
low complexity region	7228	7240	N/A	INTRINSIC
low complexity region	7326	7349	N/A	INTRINSIC
PDB:3GJO\|H	7377	7406	9e-10	PDB

Predicted Effect

possibly damaging
Transcript: ENSMUST00000182314
AA Change: K133M

PolyPhen 2 Score 0.857 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000142098
Gene: ENSMUSG00000026131
AA Change: K133M

Domain	Start	End	E-Value	Type
low complexity region	19	33	N/A	INTRINSIC
CH	85	184	8.1e-31	SMART
Pfam:CH	202	272	7.9e-5	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000182410

Predicted Effect

possibly damaging
Transcript: ENSMUST00000182697
AA Change: K125M

PolyPhen 2 Score 0.953 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000141811
Gene: ENSMUSG00000026131
AA Change: K125M

Domain	Start	End	E-Value	Type
low complexity region	11	25	N/A	INTRINSIC
CH	77	176	8.1e-31	SMART
Pfam:CH	194	264	7.5e-5	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000183034
AA Change: K263M

PolyPhen 2 Score 0.976 (Sensitivity: 0.76; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000138308
Gene: ENSMUSG00000026131
AA Change: K263M

Domain	Start	End	E-Value	Type
transmembrane domain	13	35	N/A	INTRINSIC
low complexity region	82	92	N/A	INTRINSIC
low complexity region	149	163	N/A	INTRINSIC
CH	215	314	1.62e-28	SMART
CH	331	428	3.72e-19	SMART
PDB:2ODU\|A	439	657	1e-42	PDB
low complexity region	698	723	N/A	INTRINSIC
SPEC	780	877	8.64e-9	SMART
SPEC	880	980	2.94e-11	SMART
Blast:SPEC	987	1151	5e-73	BLAST
coiled coil region	1273	1310	N/A	INTRINSIC
Blast:SPEC	1354	1463	8e-63	BLAST
SPEC	1470	1599	4.11e0	SMART
SPEC	1617	1716	4.66e0	SMART
PLEC	1715	1759	9.05e-3	SMART
PLEC	1760	1797	2.7e0	SMART
PLEC	1835	1872	2.23e0	SMART
PLEC	1873	1910	4.25e1	SMART
PLEC	1913	1948	1.39e2	SMART
PLEC	1949	1986	7.4e-8	SMART
PLEC	1989	2024	5.8e-1	SMART
PLEC	2025	2062	2.71e1	SMART
PLEC	2064	2100	4.66e0	SMART
low complexity region	2472	2485	N/A	INTRINSIC
low complexity region	2544	2559	N/A	INTRINSIC
low complexity region	2655	2669	N/A	INTRINSIC
low complexity region	2744	2771	N/A	INTRINSIC
low complexity region	2839	2853	N/A	INTRINSIC
low complexity region	2971	2977	N/A	INTRINSIC
low complexity region	3017	3025	N/A	INTRINSIC
low complexity region	3224	3235	N/A	INTRINSIC
low complexity region	3472	3492	N/A	INTRINSIC
SPEC	3499	3605	5.36e-1	SMART
low complexity region	3693	3705	N/A	INTRINSIC
low complexity region	3726	3736	N/A	INTRINSIC
SPEC	3747	3856	2.19e-1	SMART
internal_repeat_12	3949	3989	5.99e-5	PROSPERO
SPEC	4030	4149	1.75e-9	SMART
SPEC	4156	4262	3.7e-8	SMART
SPEC	4269	4368	4.56e-8	SMART
SPEC	4378	4477	3.78e0	SMART
low complexity region	4550	4566	N/A	INTRINSIC
SPEC	4625	4730	1.98e-8	SMART
SPEC	4737	4841	3.62e-11	SMART
SPEC	4851	4951	1.65e-5	SMART
SPEC	4958	5060	7.75e-11	SMART
SPEC	5067	5167	2.3e-4	SMART
SPEC	5177	5276	3.01e0	SMART
SPEC	5283	5386	2.74e-2	SMART
SPEC	5393	5497	2.46e-4	SMART
SPEC	5504	5606	1.27e-15	SMART
SPEC	5613	5715	1.69e-11	SMART
SPEC	5722	5824	9.33e-5	SMART
SPEC	5831	5933	8.07e-2	SMART
SPEC	5940	6042	3.67e-12	SMART
SPEC	6049	6150	1.97e-12	SMART
SPEC	6157	6263	4.19e-7	SMART
SPEC	6270	6372	2.06e-15	SMART
SPEC	6379	6482	2.89e-10	SMART
SPEC	6489	6591	2.61e-26	SMART
SPEC	6598	6700	5.31e-18	SMART
SPEC	6707	6809	1.25e-14	SMART
SPEC	6816	6919	9.1e-17	SMART
SPEC	6926	7027	9.3e-23	SMART
SPEC	7034	7136	5.43e-15	SMART
SPEC	7146	7276	1.5e-8	SMART
EFh	7310	7338	4.12e-3	SMART
EFh	7346	7374	1.25e-2	SMART
GAS2	7385	7463	3.08e-51	SMART
low complexity region	7511	7529	N/A	INTRINSIC
low complexity region	7539	7551	N/A	INTRINSIC
low complexity region	7637	7660	N/A	INTRINSIC
PDB:3GJO\|H	7688	7717	9e-10	PDB

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000183331

Predicted Effect

probably damaging
Transcript: ENSMUST00000187486
AA Change: K125M

PolyPhen 2 Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000140560
Gene: ENSMUSG00000026131
AA Change: K125M

Domain	Start	End	E-Value	Type
low complexity region	11	25	N/A	INTRINSIC
CH	77	176	8.1e-31	SMART
CH	193	290	1.8e-21	SMART
PDB:2ODU\|A	301	519	1e-43	PDB
SCOP:d1hcia1	308	423	4e-39	SMART
low complexity region	560	585	N/A	INTRINSIC
SPEC	642	739	5.4e-11	SMART
SPEC	742	842	1.8e-13	SMART
Blast:SPEC	849	1013	3e-73	BLAST
coiled coil region	1135	1172	N/A	INTRINSIC
Blast:SPEC	1216	1325	2e-62	BLAST
SPEC	1332	1461	2.6e-2	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000198033

Coding Region Coverage

1x: 100.0%
3x: 99.8%
10x: 98.4%
20x: 94.6%

Validation Efficiency

99% (67/68)

MGI Phenotype

PHENOTYPE: Mutations in this gene produce peripheral nervous system demyelination resulting in impaired muscle function and shorter lifespan. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 68 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310061N02Rik	C	A	16: 88,707,891 (GRCm38)	R6L	unknown	Het
Anxa11	A	G	14: 25,874,270 (GRCm38)	Q235R	possibly damaging	Het
Ap2b1	T	A	11: 83,308,239 (GRCm38)	M1K	probably null	Het
Atl2	G	A	17: 79,850,223 (GRCm38)	T563I	probably benign	Het
Azin1	A	T	15: 38,492,343 (GRCm38)	S307R	possibly damaging	Het
Ccdc153	A	G	9: 44,245,780 (GRCm38)	T118A	probably benign	Het
Chac1	G	A	2: 119,353,534 (GRCm38)	V206I	probably damaging	Het
Chrm3	A	G	13: 9,877,662 (GRCm38)	V446A	probably benign	Het
Cped1	T	C	6: 22,123,649 (GRCm38)	F467S	probably damaging	Het
Csmd3	G	A	15: 48,673,560 (GRCm38)	P82L	probably damaging	Het
Ddx60	C	T	8: 61,998,681 (GRCm38)	H1202Y	probably benign	Het
Ddx60	T	A	8: 61,977,950 (GRCm38)	S840T	probably benign	Het
Dnah8	T	A	17: 30,765,635 (GRCm38)	N3102K	probably benign	Het
Ehbp1l1	T	C	19: 5,718,757 (GRCm38)	I839M	probably benign	Het
Fam184b	T	A	5: 45,537,653 (GRCm38)	M750L	probably benign	Het
Frem2	T	C	3: 53,572,378 (GRCm38)	T1965A	probably benign	Het
Ftl1	A	T	7: 45,459,210 (GRCm38)	D41E	probably benign	Het
Garem2	G	A	5: 30,116,737 (GRCm38)	W698*	probably null	Het
Glt8d2	T	C	10: 82,652,906 (GRCm38)	Y283C	probably damaging	Het
Hars1	T	C	18: 36,773,590 (GRCm38)	E109G	possibly damaging	Het
Hspb9	T	C	11: 100,714,210 (GRCm38)	S121P	probably damaging	Het
Hus1b	A	T	13: 30,947,205 (GRCm38)	L157Q	probably damaging	Het
Hykk	A	G	9: 54,946,359 (GRCm38)	M322V	probably benign	Het
Igkv4-61	C	A	6: 69,417,154 (GRCm38)	A31S	possibly damaging	Het
Il17f	T	A	1: 20,777,907 (GRCm38)	M116L	probably benign	Het
Kif22	T	C	7: 127,028,932 (GRCm38)	K9E	possibly damaging	Het
Krt90	T	C	15: 101,559,244 (GRCm38)	E233G	probably benign	Het
Lipg	T	C	18: 74,957,236 (GRCm38)	M81V	probably benign	Het
Mocos	C	T	18: 24,701,456 (GRCm38)	S850L	probably damaging	Het
Mug2	T	A	6: 122,082,754 (GRCm38)	S1364T	probably damaging	Het
Neb	A	T	2: 52,185,328 (GRCm38)	N208K	probably benign	Het
Oca2	G	T	7: 56,328,767 (GRCm38)	R561L	probably benign	Het
Olfm5	A	G	7: 104,154,053 (GRCm38)	L401P	probably damaging	Het
Or12d17	T	A	17: 37,467,080 (GRCm38)	Y291*	probably null	Het
Or2t49	T	C	11: 58,502,340 (GRCm38)	D72G	probably damaging	Het
Or4a39	C	A	2: 89,406,522 (GRCm38)	A186S	possibly damaging	Het
Or7g16	G	A	9: 18,815,892 (GRCm38)	T134M	probably benign	Het
Or8g33	T	A	9: 39,426,891 (GRCm38)	Y60F	probably damaging	Het
Oxgr1	T	C	14: 120,022,448 (GRCm38)	N116D	probably damaging	Het
Pcdha11	G	T	18: 37,012,169 (GRCm38)		probably null	Het
Pi4ka	T	C	16: 17,358,322 (GRCm38)	I418V	probably benign	Het
Pih1d2	T	C	9: 50,618,609 (GRCm38)	V62A	probably benign	Het
Pkib	T	A	10: 57,728,138 (GRCm38)	V46E	probably damaging	Het
Pum1	A	G	4: 130,728,287 (GRCm38)		probably null	Het
Rbak	G	T	5: 143,176,552 (GRCm38)	Q19K	possibly damaging	Het
Sema3c	A	G	5: 17,576,961 (GRCm38)	T32A	probably damaging	Het
Shprh	T	C	10: 11,167,873 (GRCm38)	W835R	probably damaging	Het
Sis	T	G	3: 72,911,854 (GRCm38)	K1456N	probably damaging	Het
Slc4a4	A	T	5: 89,179,729 (GRCm38)	N675I	probably benign	Het
Slc8a3	C	A	12: 81,315,627 (GRCm38)	M139I	probably damaging	Het
Sorcs3	T	C	19: 48,802,759 (GRCm38)	F1182S	probably damaging	Het
St8sia2	A	T	7: 73,971,921 (GRCm38)	I96N	probably damaging	Het
Stx19	T	C	16: 62,822,057 (GRCm38)	S79P	probably damaging	Het
Tecta	C	T	9: 42,375,267 (GRCm38)	V698M	probably damaging	Het
Timm22	T	C	11: 76,411,139 (GRCm38)	S150P	probably damaging	Het
Tjp1	C	T	7: 65,313,205 (GRCm38)	D995N	possibly damaging	Het
Tmem135	T	A	7: 89,147,794 (GRCm38)	T365S	probably benign	Het
Tmem174	T	C	13: 98,636,981 (GRCm38)	T114A	probably benign	Het
Tnc	A	G	4: 64,007,816 (GRCm38)	I909T	probably benign	Het
Trcg1	A	G	9: 57,241,330 (GRCm38)	I62V	possibly damaging	Het
Tulp1	A	T	17: 28,356,031 (GRCm38)	*487K	probably null	Het
Unc79	T	A	12: 103,131,646 (GRCm38)	V1826E	possibly damaging	Het
Vmn2r13	A	T	5: 109,174,116 (GRCm38)	N238K	probably damaging	Het
Vmn2r22	T	A	6: 123,637,738 (GRCm38)	N298Y	probably damaging	Het
Vmn2r23	T	A	6: 123,712,902 (GRCm38)	F246I	probably damaging	Het
Vps9d1	A	C	8: 123,248,639 (GRCm38)	V194G	probably damaging	Het
Zfp260	A	T	7: 30,104,810 (GRCm38)	H45L	possibly damaging	Het
Zfp846	A	T	9: 20,593,720 (GRCm38)	H292L	possibly damaging	Het

Other mutations in Dst

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00233:Dst	APN	1	34,251,839 (GRCm38)	missense	probably damaging	1.00
IGL00309:Dst	APN	1	34,160,652 (GRCm38)	missense	probably damaging	1.00
IGL00334:Dst	APN	1	34,166,292 (GRCm38)	missense	probably damaging	1.00
IGL00470:Dst	APN	1	34,188,962 (GRCm38)	missense	probably damaging	1.00
IGL00481:Dst	APN	1	34,169,329 (GRCm38)	splice site	probably benign
IGL00499:Dst	APN	1	34,290,423 (GRCm38)	missense	probably damaging	0.99
IGL00803:Dst	APN	1	34,164,124 (GRCm38)	missense	possibly damaging	0.89
IGL00850:Dst	APN	1	34,306,624 (GRCm38)	missense	probably damaging	1.00
IGL00957:Dst	APN	1	34,228,407 (GRCm38)	missense	probably benign	0.27
IGL00975:Dst	APN	1	34,188,312 (GRCm38)	missense	possibly damaging	0.86
IGL00984:Dst	APN	1	34,256,320 (GRCm38)	missense	probably damaging	1.00
IGL01284:Dst	APN	1	34,163,928 (GRCm38)	missense	probably damaging	1.00
IGL01393:Dst	APN	1	34,167,625 (GRCm38)	missense	possibly damaging	0.91
IGL01397:Dst	APN	1	34,257,744 (GRCm38)	missense	probably damaging	1.00
IGL01399:Dst	APN	1	34,117,517 (GRCm38)	missense	probably benign	0.41
IGL01412:Dst	APN	1	34,242,620 (GRCm38)	missense	probably benign	0.21
IGL01527:Dst	APN	1	34,247,653 (GRCm38)	missense	probably damaging	1.00
IGL01537:Dst	APN	1	34,275,320 (GRCm38)	missense	probably damaging	1.00
IGL01618:Dst	APN	1	34,188,909 (GRCm38)	nonsense	probably null
IGL01636:Dst	APN	1	34,215,569 (GRCm38)	missense	probably damaging	1.00
IGL01642:Dst	APN	1	34,189,389 (GRCm38)	missense	probably damaging	1.00
IGL01672:Dst	APN	1	34,225,693 (GRCm38)	missense	probably damaging	1.00
IGL01685:Dst	APN	1	34,170,452 (GRCm38)	missense	probably damaging	0.99
IGL01694:Dst	APN	1	34,188,160 (GRCm38)	missense	probably benign	0.13
IGL01777:Dst	APN	1	34,199,397 (GRCm38)	missense	probably benign	0.07
IGL01800:Dst	APN	1	34,262,092 (GRCm38)	missense	probably damaging	1.00
IGL01811:Dst	APN	1	34,164,092 (GRCm38)	missense	probably damaging	1.00
IGL01960:Dst	APN	1	34,290,489 (GRCm38)	missense	probably damaging	1.00
IGL02031:Dst	APN	1	34,189,917 (GRCm38)	missense	possibly damaging	0.95
IGL02103:Dst	APN	1	34,190,118 (GRCm38)	missense	possibly damaging	0.90
IGL02121:Dst	APN	1	34,228,657 (GRCm38)	missense	probably damaging	1.00
IGL02315:Dst	APN	1	34,198,665 (GRCm38)	missense	probably damaging	1.00
IGL02317:Dst	APN	1	34,295,163 (GRCm38)	missense	probably damaging	1.00
IGL02469:Dst	APN	1	34,188,828 (GRCm38)	missense	probably damaging	1.00
IGL02492:Dst	APN	1	34,152,193 (GRCm38)	splice site	probably benign
IGL02510:Dst	APN	1	34,229,251 (GRCm38)	splice site	probably null
IGL02522:Dst	APN	1	34,250,700 (GRCm38)	splice site	probably benign
IGL02540:Dst	APN	1	34,135,204 (GRCm38)	missense	probably damaging	1.00
IGL02588:Dst	APN	1	34,117,484 (GRCm38)	missense	probably damaging	1.00
IGL02676:Dst	APN	1	34,307,587 (GRCm38)	missense	probably damaging	1.00
IGL02688:Dst	APN	1	34,195,952 (GRCm38)	missense	probably damaging	1.00
IGL02700:Dst	APN	1	34,262,120 (GRCm38)	missense	probably damaging	1.00
IGL02794:Dst	APN	1	34,270,829 (GRCm38)	missense	probably damaging	1.00
IGL02823:Dst	APN	1	34,192,083 (GRCm38)	missense	possibly damaging	0.83
IGL02935:Dst	APN	1	34,186,845 (GRCm38)	nonsense	probably null
IGL02940:Dst	APN	1	34,289,587 (GRCm38)	missense	probably benign	0.36
IGL02994:Dst	APN	1	34,229,252 (GRCm38)	splice site	probably benign
IGL02996:Dst	APN	1	34,188,398 (GRCm38)	missense	possibly damaging	0.93
IGL02998:Dst	APN	1	34,268,275 (GRCm38)	missense	probably damaging	1.00
IGL03027:Dst	APN	1	34,186,025 (GRCm38)	missense	possibly damaging	0.51
IGL03033:Dst	APN	1	34,169,745 (GRCm38)	splice site	probably benign
IGL03099:Dst	APN	1	34,275,781 (GRCm38)	missense	probably damaging	1.00
IGL03119:Dst	APN	1	34,161,062 (GRCm38)	missense	probably damaging	1.00
IGL03121:Dst	APN	1	34,217,803 (GRCm38)	splice site	probably benign
IGL03132:Dst	APN	1	34,256,641 (GRCm38)	missense	probably benign	0.06
IGL03220:Dst	APN	1	34,185,995 (GRCm38)	missense	probably damaging	0.99
IGL03230:Dst	APN	1	34,184,052 (GRCm38)	nonsense	probably null
IGL03245:Dst	APN	1	34,211,148 (GRCm38)	splice site	probably null
IGL03380:Dst	APN	1	34,257,800 (GRCm38)	missense	probably damaging	1.00
Doodle	UTSW	1	34,208,558 (GRCm38)	nonsense	probably null
dyssed	UTSW	1	34,256,353 (GRCm38)	critical splice donor site	probably null
gobble	UTSW	1	34,165,155 (GRCm38)	critical splice donor site	probably null
Phelps	UTSW	1	34,223,795 (GRCm38)	splice site	probably null
tinsel	UTSW	1	34,164,167 (GRCm38)	missense	probably damaging	1.00
Wastable	UTSW	1	34,295,289 (GRCm38)	missense	probably damaging	1.00
E0370:Dst	UTSW	1	34,249,471 (GRCm38)	splice site	probably benign
FR4304:Dst	UTSW	1	34,200,964 (GRCm38)	missense	probably damaging	0.99
G1citation:Dst	UTSW	1	34,275,674 (GRCm38)	missense	probably damaging	0.99
IGL02799:Dst	UTSW	1	34,179,849 (GRCm38)	missense	possibly damaging	0.92
R0006:Dst	UTSW	1	34,228,918 (GRCm38)	missense	probably benign	0.30
R0006:Dst	UTSW	1	34,228,918 (GRCm38)	missense	probably benign	0.30
R0023:Dst	UTSW	1	34,189,119 (GRCm38)	missense	probably damaging	1.00
R0023:Dst	UTSW	1	34,189,119 (GRCm38)	missense	probably damaging	1.00
R0024:Dst	UTSW	1	34,189,119 (GRCm38)	missense	probably damaging	1.00
R0027:Dst	UTSW	1	34,189,119 (GRCm38)	missense	probably damaging	1.00
R0049:Dst	UTSW	1	34,275,781 (GRCm38)	missense	probably damaging	1.00
R0053:Dst	UTSW	1	34,294,550 (GRCm38)	splice site	probably null
R0053:Dst	UTSW	1	34,294,550 (GRCm38)	splice site	probably null
R0058:Dst	UTSW	1	34,006,224 (GRCm38)	missense	possibly damaging	0.93
R0066:Dst	UTSW	1	34,189,553 (GRCm38)	missense	possibly damaging	0.67
R0066:Dst	UTSW	1	34,189,553 (GRCm38)	missense	possibly damaging	0.67
R0085:Dst	UTSW	1	34,229,187 (GRCm38)	missense	probably damaging	1.00
R0125:Dst	UTSW	1	34,270,903 (GRCm38)	missense	probably damaging	1.00
R0152:Dst	UTSW	1	34,189,119 (GRCm38)	missense	probably damaging	1.00
R0165:Dst	UTSW	1	34,154,646 (GRCm38)	splice site	probably benign
R0172:Dst	UTSW	1	34,270,854 (GRCm38)	missense	probably damaging	1.00
R0207:Dst	UTSW	1	34,186,935 (GRCm38)	missense	probably benign	0.02
R0219:Dst	UTSW	1	34,303,478 (GRCm38)	missense	probably damaging	0.99
R0349:Dst	UTSW	1	34,199,553 (GRCm38)	missense	probably benign	0.12
R0386:Dst	UTSW	1	34,217,836 (GRCm38)	missense	probably damaging	1.00
R0389:Dst	UTSW	1	34,294,550 (GRCm38)	splice site	probably null
R0395:Dst	UTSW	1	34,189,119 (GRCm38)	missense	probably damaging	1.00
R0423:Dst	UTSW	1	34,278,035 (GRCm38)	missense	possibly damaging	0.95
R0443:Dst	UTSW	1	34,294,550 (GRCm38)	splice site	probably null
R0472:Dst	UTSW	1	34,266,960 (GRCm38)	critical splice donor site	probably null
R0490:Dst	UTSW	1	34,307,368 (GRCm38)	nonsense	probably null
R0513:Dst	UTSW	1	34,219,531 (GRCm38)	splice site	probably benign
R0539:Dst	UTSW	1	34,189,119 (GRCm38)	missense	probably damaging	1.00
R0562:Dst	UTSW	1	34,227,981 (GRCm38)	missense	probably damaging	1.00
R0569:Dst	UTSW	1	34,293,427 (GRCm38)	missense	probably damaging	1.00
R0600:Dst	UTSW	1	34,189,119 (GRCm38)	missense	probably damaging	1.00
R0608:Dst	UTSW	1	34,290,356 (GRCm38)	splice site	probably null
R0609:Dst	UTSW	1	34,266,960 (GRCm38)	critical splice donor site	probably null
R0630:Dst	UTSW	1	34,199,473 (GRCm38)	missense	probably damaging	0.98
R0630:Dst	UTSW	1	34,193,450 (GRCm38)	missense	probably benign	0.05
R0632:Dst	UTSW	1	34,271,413 (GRCm38)	missense	probably damaging	1.00
R0713:Dst	UTSW	1	34,189,119 (GRCm38)	missense	probably damaging	1.00
R0724:Dst	UTSW	1	34,188,677 (GRCm38)	missense	probably benign	0.00
R0761:Dst	UTSW	1	34,182,767 (GRCm38)	missense	probably benign	0.33
R0801:Dst	UTSW	1	34,170,389 (GRCm38)	missense	probably damaging	0.99
R0829:Dst	UTSW	1	34,163,220 (GRCm38)	missense	probably damaging	1.00
R0939:Dst	UTSW	1	34,244,383 (GRCm38)	missense	probably damaging	1.00
R0945:Dst	UTSW	1	34,271,419 (GRCm38)	missense	probably damaging	1.00
R0992:Dst	UTSW	1	34,199,536 (GRCm38)	missense	probably damaging	0.97
R1018:Dst	UTSW	1	34,194,093 (GRCm38)	missense	probably damaging	1.00
R1077:Dst	UTSW	1	34,164,167 (GRCm38)	missense	probably damaging	1.00
R1079:Dst	UTSW	1	34,186,863 (GRCm38)	missense	possibly damaging	0.86
R1127:Dst	UTSW	1	34,275,277 (GRCm38)	missense	probably damaging	1.00
R1129:Dst	UTSW	1	34,199,554 (GRCm38)	missense	probably benign	0.28
R1141:Dst	UTSW	1	34,188,696 (GRCm38)	missense	possibly damaging	0.85
R1167:Dst	UTSW	1	34,223,858 (GRCm38)	missense	probably damaging	1.00
R1195:Dst	UTSW	1	34,211,154 (GRCm38)	missense	probably damaging	1.00
R1195:Dst	UTSW	1	34,211,154 (GRCm38)	missense	probably damaging	1.00
R1195:Dst	UTSW	1	34,211,154 (GRCm38)	missense	probably damaging	1.00
R1333:Dst	UTSW	1	34,228,347 (GRCm38)	missense	probably damaging	1.00
R1352:Dst	UTSW	1	34,229,248 (GRCm38)	critical splice donor site	probably null
R1365:Dst	UTSW	1	34,188,194 (GRCm38)	missense	probably benign	0.02
R1382:Dst	UTSW	1	34,268,833 (GRCm38)	missense	probably damaging	0.99
R1389:Dst	UTSW	1	34,211,232 (GRCm38)	missense	probably damaging	1.00
R1394:Dst	UTSW	1	34,165,155 (GRCm38)	critical splice donor site	probably null
R1395:Dst	UTSW	1	34,165,155 (GRCm38)	critical splice donor site	probably null
R1435:Dst	UTSW	1	34,113,945 (GRCm38)	missense	probably damaging	1.00
R1450:Dst	UTSW	1	34,212,259 (GRCm38)	missense	probably damaging	0.99
R1450:Dst	UTSW	1	34,188,395 (GRCm38)	missense	probably damaging	1.00
R1453:Dst	UTSW	1	34,189,446 (GRCm38)	missense	possibly damaging	0.85
R1479:Dst	UTSW	1	34,264,515 (GRCm38)	splice site	probably null
R1483:Dst	UTSW	1	34,252,998 (GRCm38)	missense	probably damaging	1.00
R1491:Dst	UTSW	1	34,154,594 (GRCm38)	missense	probably damaging	0.99
R1536:Dst	UTSW	1	34,260,372 (GRCm38)	splice site	probably benign
R1551:Dst	UTSW	1	34,192,212 (GRCm38)	missense	probably benign	0.01
R1573:Dst	UTSW	1	34,201,231 (GRCm38)	missense	probably damaging	1.00
R1614:Dst	UTSW	1	34,275,263 (GRCm38)	missense	probably damaging	1.00
R1615:Dst	UTSW	1	34,199,371 (GRCm38)	missense	probably damaging	1.00
R1645:Dst	UTSW	1	34,225,722 (GRCm38)	missense	probably damaging	1.00
R1655:Dst	UTSW	1	34,282,576 (GRCm38)	nonsense	probably null
R1663:Dst	UTSW	1	34,163,385 (GRCm38)	missense	probably damaging	1.00
R1674:Dst	UTSW	1	34,223,795 (GRCm38)	splice site	probably null
R1702:Dst	UTSW	1	34,167,340 (GRCm38)	missense	probably damaging	1.00
R1707:Dst	UTSW	1	34,167,646 (GRCm38)	missense	probably damaging	1.00
R1747:Dst	UTSW	1	34,160,709 (GRCm38)	missense	probably damaging	1.00
R1760:Dst	UTSW	1	34,228,603 (GRCm38)	missense	probably damaging	1.00
R1773:Dst	UTSW	1	34,291,899 (GRCm38)	missense	probably damaging	0.99
R1793:Dst	UTSW	1	34,152,471 (GRCm38)	nonsense	probably null
R1842:Dst	UTSW	1	34,164,119 (GRCm38)	missense	probably null	0.98
R1869:Dst	UTSW	1	34,252,832 (GRCm38)	missense	probably damaging	0.99
R1879:Dst	UTSW	1	34,188,843 (GRCm38)	missense	probably benign	0.15
R1883:Dst	UTSW	1	34,189,308 (GRCm38)	missense	possibly damaging	0.74
R1912:Dst	UTSW	1	34,291,850 (GRCm38)	missense	probably damaging	1.00
R1920:Dst	UTSW	1	34,161,029 (GRCm38)	missense	probably damaging	0.99
R1921:Dst	UTSW	1	34,161,029 (GRCm38)	missense	probably damaging	0.99
R1943:Dst	UTSW	1	34,228,369 (GRCm38)	missense	possibly damaging	0.67
R1958:Dst	UTSW	1	34,163,721 (GRCm38)	missense	probably damaging	1.00
R1962:Dst	UTSW	1	34,191,016 (GRCm38)	missense	possibly damaging	0.47
R1991:Dst	UTSW	1	34,190,258 (GRCm38)	missense	probably benign	0.11
R1998:Dst	UTSW	1	34,256,347 (GRCm38)	missense	probably damaging	1.00
R2001:Dst	UTSW	1	34,184,063 (GRCm38)	missense	probably damaging	0.97
R2007:Dst	UTSW	1	34,226,012 (GRCm38)	splice site	probably benign
R2021:Dst	UTSW	1	34,166,291 (GRCm38)	missense	possibly damaging	0.70
R2022:Dst	UTSW	1	34,166,291 (GRCm38)	missense	possibly damaging	0.70
R2035:Dst	UTSW	1	34,271,413 (GRCm38)	missense	probably damaging	1.00
R2077:Dst	UTSW	1	34,211,170 (GRCm38)	missense	probably damaging	1.00
R2103:Dst	UTSW	1	34,190,258 (GRCm38)	missense	probably benign	0.11
R2111:Dst	UTSW	1	34,169,178 (GRCm38)	missense	probably damaging	1.00
R2112:Dst	UTSW	1	34,169,178 (GRCm38)	missense	probably damaging	1.00
R2113:Dst	UTSW	1	34,275,236 (GRCm38)	missense	probably damaging	0.97
R2201:Dst	UTSW	1	34,195,921 (GRCm38)	missense	possibly damaging	0.60
R2214:Dst	UTSW	1	34,271,401 (GRCm38)	missense	probably damaging	1.00
R2219:Dst	UTSW	1	34,170,433 (GRCm38)	missense	probably damaging	1.00
R2233:Dst	UTSW	1	34,274,262 (GRCm38)	missense	probably damaging	1.00
R2267:Dst	UTSW	1	34,295,466 (GRCm38)	missense	probably damaging	1.00
R2290:Dst	UTSW	1	34,229,200 (GRCm38)	missense	probably damaging	1.00
R2323:Dst	UTSW	1	34,228,437 (GRCm38)	missense	possibly damaging	0.93
R2424:Dst	UTSW	1	34,167,060 (GRCm38)	missense	probably damaging	1.00
R2426:Dst	UTSW	1	34,192,812 (GRCm38)	missense	probably benign	0.03
R2495:Dst	UTSW	1	34,199,373 (GRCm38)	missense	probably damaging	0.99
R2507:Dst	UTSW	1	34,188,417 (GRCm38)	missense	possibly damaging	0.85
R2507:Dst	UTSW	1	34,011,909 (GRCm38)	missense	probably damaging	0.98
R2510:Dst	UTSW	1	34,212,286 (GRCm38)	missense	probably benign
R2831:Dst	UTSW	1	34,275,292 (GRCm38)	missense	probably damaging	1.00
R2929:Dst	UTSW	1	34,167,062 (GRCm38)	nonsense	probably null
R3033:Dst	UTSW	1	34,152,285 (GRCm38)	missense	probably damaging	0.99
R3121:Dst	UTSW	1	34,289,648 (GRCm38)	missense	probably damaging	1.00
R3424:Dst	UTSW	1	34,198,505 (GRCm38)	splice site	probably benign
R3437:Dst	UTSW	1	34,190,222 (GRCm38)	missense	probably damaging	1.00
R3699:Dst	UTSW	1	34,213,074 (GRCm38)	splice site	probably benign
R3739:Dst	UTSW	1	34,268,894 (GRCm38)	splice site	probably benign
R3796:Dst	UTSW	1	34,181,915 (GRCm38)	missense	probably benign	0.15
R3847:Dst	UTSW	1	34,212,319 (GRCm38)	missense	probably damaging	1.00
R3848:Dst	UTSW	1	34,212,319 (GRCm38)	missense	probably damaging	1.00
R3849:Dst	UTSW	1	34,212,319 (GRCm38)	missense	probably damaging	1.00
R3850:Dst	UTSW	1	34,189,274 (GRCm38)	nonsense	probably null
R3850:Dst	UTSW	1	34,212,319 (GRCm38)	missense	probably damaging	1.00
R3873:Dst	UTSW	1	34,289,620 (GRCm38)	missense	probably damaging	1.00
R3875:Dst	UTSW	1	34,171,247 (GRCm38)	missense	probably damaging	1.00
R3973:Dst	UTSW	1	34,011,898 (GRCm38)	missense	probably benign	0.34
R4014:Dst	UTSW	1	34,191,282 (GRCm38)	nonsense	probably null
R4043:Dst	UTSW	1	34,190,684 (GRCm38)	missense	probably benign	0.03
R4057:Dst	UTSW	1	34,186,054 (GRCm38)	splice site	probably benign
R4074:Dst	UTSW	1	34,228,461 (GRCm38)	missense	probably damaging	0.97
R4074:Dst	UTSW	1	34,192,269 (GRCm38)	missense	probably benign	0.20
R4075:Dst	UTSW	1	34,192,269 (GRCm38)	missense	probably benign	0.20
R4076:Dst	UTSW	1	34,192,269 (GRCm38)	missense	probably benign	0.20
R4206:Dst	UTSW	1	34,212,247 (GRCm38)	missense	probably damaging	1.00
R4230:Dst	UTSW	1	34,195,828 (GRCm38)	missense	probably benign	0.04
R4242:Dst	UTSW	1	34,006,216 (GRCm38)	missense	possibly damaging	0.88
R4273:Dst	UTSW	1	34,192,340 (GRCm38)	missense	possibly damaging	0.72
R4366:Dst	UTSW	1	34,251,878 (GRCm38)	missense	probably damaging	1.00
R4370:Dst	UTSW	1	34,251,728 (GRCm38)	frame shift	probably null
R4379:Dst	UTSW	1	34,227,975 (GRCm38)	missense	probably benign	0.07
R4379:Dst	UTSW	1	34,163,235 (GRCm38)	missense	probably damaging	1.00
R4380:Dst	UTSW	1	34,163,235 (GRCm38)	missense	probably damaging	1.00
R4381:Dst	UTSW	1	34,163,235 (GRCm38)	missense	probably damaging	1.00
R4423:Dst	UTSW	1	34,188,393 (GRCm38)	missense	possibly damaging	0.76
R4427:Dst	UTSW	1	34,181,460 (GRCm38)	missense	probably benign	0.19
R4456:Dst	UTSW	1	34,190,719 (GRCm38)	missense	probably benign	0.06
R4469:Dst	UTSW	1	34,191,842 (GRCm38)	missense	probably benign	0.02
R4502:Dst	UTSW	1	34,247,691 (GRCm38)	missense	probably damaging	0.99
R4503:Dst	UTSW	1	34,262,253 (GRCm38)	critical splice donor site	probably null
R4545:Dst	UTSW	1	34,188,738 (GRCm38)	missense	probably damaging	0.99
R4610:Dst	UTSW	1	34,169,856 (GRCm38)	missense	probably damaging	1.00
R4633:Dst	UTSW	1	34,170,434 (GRCm38)	missense	probably damaging	1.00
R4675:Dst	UTSW	1	34,275,703 (GRCm38)	missense	possibly damaging	0.94
R4687:Dst	UTSW	1	34,201,123 (GRCm38)	missense	probably damaging	1.00
R4739:Dst	UTSW	1	34,191,147 (GRCm38)	missense	probably benign	0.01
R4751:Dst	UTSW	1	34,191,884 (GRCm38)	missense	probably benign	0.21
R4754:Dst	UTSW	1	34,212,309 (GRCm38)	missense	probably damaging	1.00
R4771:Dst	UTSW	1	34,249,484 (GRCm38)	missense	probably damaging	1.00
R4819:Dst	UTSW	1	33,968,835 (GRCm38)	missense	probably benign	0.03
R4830:Dst	UTSW	1	34,198,505 (GRCm38)	splice site	probably null
R4839:Dst	UTSW	1	34,190,862 (GRCm38)	missense	probably damaging	0.96
R4845:Dst	UTSW	1	34,193,127 (GRCm38)	missense	probably benign	0.02
R4904:Dst	UTSW	1	34,169,798 (GRCm38)	missense	probably damaging	0.99
R4932:Dst	UTSW	1	34,228,683 (GRCm38)	missense	possibly damaging	0.47
R4934:Dst	UTSW	1	34,208,588 (GRCm38)	missense	probably damaging	1.00
R4952:Dst	UTSW	1	34,271,422 (GRCm38)	missense	probably damaging	1.00
R4961:Dst	UTSW	1	33,968,823 (GRCm38)	missense	possibly damaging	0.53
R4976:Dst	UTSW	1	34,195,969 (GRCm38)	nonsense	probably null
R4980:Dst	UTSW	1	34,256,288 (GRCm38)	missense	probably damaging	1.00
R5011:Dst	UTSW	1	34,250,647 (GRCm38)	missense	probably damaging	1.00
R5013:Dst	UTSW	1	34,250,647 (GRCm38)	missense	probably damaging	1.00
R5059:Dst	UTSW	1	34,163,346 (GRCm38)	missense	possibly damaging	0.70
R5074:Dst	UTSW	1	34,295,263 (GRCm38)	missense	probably damaging	1.00
R5114:Dst	UTSW	1	34,202,559 (GRCm38)	missense	probably damaging	0.98
R5119:Dst	UTSW	1	34,195,969 (GRCm38)	nonsense	probably null
R5182:Dst	UTSW	1	34,179,086 (GRCm38)	missense	probably benign
R5236:Dst	UTSW	1	34,164,417 (GRCm38)	missense	probably damaging	1.00
R5240:Dst	UTSW	1	34,208,558 (GRCm38)	nonsense	probably null
R5254:Dst	UTSW	1	34,177,931 (GRCm38)	nonsense	probably null
R5275:Dst	UTSW	1	34,180,148 (GRCm38)	missense	probably benign	0.13
R5281:Dst	UTSW	1	34,257,782 (GRCm38)	missense	probably benign	0.29
R5299:Dst	UTSW	1	34,135,092 (GRCm38)	missense	probably damaging	1.00
R5316:Dst	UTSW	1	34,223,848 (GRCm38)	missense	probably damaging	0.97
R5319:Dst	UTSW	1	34,225,977 (GRCm38)	missense	possibly damaging	0.95
R5425:Dst	UTSW	1	34,179,750 (GRCm38)	missense	probably benign	0.00
R5443:Dst	UTSW	1	34,228,539 (GRCm38)	missense	probably damaging	1.00
R5522:Dst	UTSW	1	34,257,873 (GRCm38)	missense	possibly damaging	0.46
R5537:Dst	UTSW	1	34,189,878 (GRCm38)	missense	probably benign	0.25
R5548:Dst	UTSW	1	34,189,328 (GRCm38)	missense	probably benign
R5557:Dst	UTSW	1	34,282,586 (GRCm38)	missense	probably damaging	1.00
R5597:Dst	UTSW	1	34,192,713 (GRCm38)	missense	probably benign	0.07
R5623:Dst	UTSW	1	34,190,133 (GRCm38)	missense	possibly damaging	0.56
R5630:Dst	UTSW	1	34,188,785 (GRCm38)	frame shift	probably null
R5660:Dst	UTSW	1	34,282,493 (GRCm38)	missense	probably damaging	1.00
R5730:Dst	UTSW	1	34,117,526 (GRCm38)	splice site	probably null
R5762:Dst	UTSW	1	34,179,357 (GRCm38)	missense	probably damaging	0.99
R5810:Dst	UTSW	1	34,183,040 (GRCm38)	intron	probably benign
R5816:Dst	UTSW	1	34,179,234 (GRCm38)	missense	probably benign
R5846:Dst	UTSW	1	34,195,861 (GRCm38)	nonsense	probably null
R5874:Dst	UTSW	1	34,179,589 (GRCm38)	missense	probably damaging	0.98
R5899:Dst	UTSW	1	34,295,289 (GRCm38)	missense	probably damaging	1.00
R5923:Dst	UTSW	1	34,181,759 (GRCm38)	missense	probably benign	0.00
R5936:Dst	UTSW	1	34,307,458 (GRCm38)	missense	probably damaging	1.00
R5946:Dst	UTSW	1	34,174,192 (GRCm38)	missense	probably benign	0.01
R5950:Dst	UTSW	1	34,262,060 (GRCm38)	missense	probably damaging	1.00
R5958:Dst	UTSW	1	34,186,050 (GRCm38)	missense	probably damaging	0.97
R5973:Dst	UTSW	1	34,156,857 (GRCm38)	missense	probably damaging	1.00
R5979:Dst	UTSW	1	34,160,372 (GRCm38)	intron	probably benign
R5980:Dst	UTSW	1	34,182,891 (GRCm38)	missense	probably benign	0.34
R5984:Dst	UTSW	1	34,172,263 (GRCm38)	missense	probably benign	0.05
R6000:Dst	UTSW	1	34,212,223 (GRCm38)	missense	possibly damaging	0.92
R6014:Dst	UTSW	1	34,264,834 (GRCm38)	missense	probably damaging	1.00
R6042:Dst	UTSW	1	34,188,972 (GRCm38)	missense	probably damaging	1.00
R6064:Dst	UTSW	1	34,194,051 (GRCm38)	missense	probably damaging	1.00
R6126:Dst	UTSW	1	34,228,183 (GRCm38)	missense	probably damaging	1.00
R6157:Dst	UTSW	1	34,211,172 (GRCm38)	missense	probably damaging	1.00
R6162:Dst	UTSW	1	34,006,237 (GRCm38)	missense	probably damaging	0.99
R6185:Dst	UTSW	1	34,173,080 (GRCm38)	missense	probably damaging	0.99
R6226:Dst	UTSW	1	34,270,874 (GRCm38)	missense	probably damaging	1.00
R6227:Dst	UTSW	1	34,194,540 (GRCm38)	missense	probably benign	0.41
R6232:Dst	UTSW	1	34,188,172 (GRCm38)	missense	probably damaging	1.00
R6259:Dst	UTSW	1	34,182,396 (GRCm38)	missense	probably benign	0.26
R6267:Dst	UTSW	1	34,228,672 (GRCm38)	missense	probably damaging	1.00
R6273:Dst	UTSW	1	34,275,266 (GRCm38)	missense	probably damaging	1.00
R6284:Dst	UTSW	1	34,229,085 (GRCm38)	missense	probably damaging	1.00
R6347:Dst	UTSW	1	34,179,684 (GRCm38)	splice site	probably null
R6365:Dst	UTSW	1	34,191,927 (GRCm38)	missense	probably damaging	1.00
R6385:Dst	UTSW	1	34,307,468 (GRCm38)	missense	possibly damaging	0.85
R6389:Dst	UTSW	1	34,193,184 (GRCm38)	missense	probably damaging	0.99
R6395:Dst	UTSW	1	34,182,690 (GRCm38)	missense	probably benign	0.17
R6467:Dst	UTSW	1	34,295,196 (GRCm38)	missense	probably damaging	1.00
R6470:Dst	UTSW	1	34,295,237 (GRCm38)	missense	probably damaging	1.00
R6477:Dst	UTSW	1	34,208,728 (GRCm38)	splice site	probably null
R6485:Dst	UTSW	1	34,294,529 (GRCm38)	missense	probably damaging	1.00
R6491:Dst	UTSW	1	34,193,012 (GRCm38)	missense	probably benign	0.10
R6525:Dst	UTSW	1	34,163,135 (GRCm38)	missense	probably damaging	1.00
R6533:Dst	UTSW	1	34,303,509 (GRCm38)	missense	probably benign	0.08
R6595:Dst	UTSW	1	34,250,680 (GRCm38)	missense	probably damaging	1.00
R6622:Dst	UTSW	1	34,179,251 (GRCm38)	missense	probably benign	0.22
R6646:Dst	UTSW	1	34,268,807 (GRCm38)	missense	possibly damaging	0.80
R6648:Dst	UTSW	1	34,262,041 (GRCm38)	missense	possibly damaging	0.84
R6700:Dst	UTSW	1	34,256,323 (GRCm38)	missense	probably damaging	1.00
R6743:Dst	UTSW	1	34,270,890 (GRCm38)	missense	probably damaging	1.00
R6761:Dst	UTSW	1	34,214,550 (GRCm38)	missense	probably damaging	1.00
R6766:Dst	UTSW	1	34,294,483 (GRCm38)	missense	probably damaging	1.00
R6768:Dst	UTSW	1	34,181,712 (GRCm38)	missense	probably damaging	0.98
R6810:Dst	UTSW	1	34,212,298 (GRCm38)	missense	probably damaging	1.00
R6815:Dst	UTSW	1	34,228,369 (GRCm38)	missense	possibly damaging	0.67
R6820:Dst	UTSW	1	34,211,256 (GRCm38)	missense	probably damaging	1.00
R6822:Dst	UTSW	1	34,275,674 (GRCm38)	missense	probably damaging	0.99
R6831:Dst	UTSW	1	34,190,684 (GRCm38)	missense	probably benign	0.03
R6874:Dst	UTSW	1	34,289,651 (GRCm38)	missense	probably benign	0.29
R6945:Dst	UTSW	1	34,190,490 (GRCm38)	missense	probably damaging	1.00
R6985:Dst	UTSW	1	34,190,853 (GRCm38)	missense	probably benign	0.08
R6995:Dst	UTSW	1	34,166,234 (GRCm38)	missense	probably damaging	1.00
R7038:Dst	UTSW	1	34,182,798 (GRCm38)	nonsense	probably null
R7043:Dst	UTSW	1	34,257,911 (GRCm38)	missense	probably damaging	0.99
R7070:Dst	UTSW	1	34,275,302 (GRCm38)	missense	probably damaging	1.00
R7097:Dst	UTSW	1	34,169,260 (GRCm38)	missense	probably damaging	1.00
R7139:Dst	UTSW	1	34,299,807 (GRCm38)	missense	probably damaging	0.97
R7144:Dst	UTSW	1	34,152,243 (GRCm38)	missense	probably damaging	1.00
R7145:Dst	UTSW	1	34,189,882 (GRCm38)	missense	probably benign
R7158:Dst	UTSW	1	34,274,285 (GRCm38)	missense	probably benign
R7207:Dst	UTSW	1	34,163,337 (GRCm38)	missense	probably damaging	0.98
R7320:Dst	UTSW	1	34,191,094 (GRCm38)	missense	probably benign
R7324:Dst	UTSW	1	34,006,224 (GRCm38)	missense	possibly damaging	0.93
R7327:Dst	UTSW	1	34,201,405 (GRCm38)	missense	probably damaging	1.00
R7340:Dst	UTSW	1	34,190,729 (GRCm38)	missense	probably benign	0.01
R7358:Dst	UTSW	1	34,191,673 (GRCm38)	missense	probably benign
R7373:Dst	UTSW	1	34,188,391 (GRCm38)	missense	probably benign	0.02
R7376:Dst	UTSW	1	34,192,689 (GRCm38)	missense	probably benign
R7453:Dst	UTSW	1	34,191,358 (GRCm38)	missense	possibly damaging	0.95
R7467:Dst	UTSW	1	34,191,155 (GRCm38)	missense	probably benign	0.00
R7471:Dst	UTSW	1	34,194,570 (GRCm38)	missense	possibly damaging	0.49
R7472:Dst	UTSW	1	34,218,497 (GRCm38)	missense	probably benign	0.02
R7485:Dst	UTSW	1	34,274,189 (GRCm38)	missense	probably benign	0.31
R7504:Dst	UTSW	1	34,201,017 (GRCm38)	missense	probably damaging	1.00
R7516:Dst	UTSW	1	34,170,479 (GRCm38)	missense	probably benign	0.10
R7524:Dst	UTSW	1	34,291,893 (GRCm38)	missense	possibly damaging	0.94
R7528:Dst	UTSW	1	34,294,522 (GRCm38)	missense	probably damaging	1.00
R7560:Dst	UTSW	1	34,182,451 (GRCm38)	missense	possibly damaging	0.92
R7582:Dst	UTSW	1	34,169,883 (GRCm38)	missense	probably damaging	1.00
R7585:Dst	UTSW	1	34,114,015 (GRCm38)	missense	possibly damaging	0.50
R7594:Dst	UTSW	1	34,213,013 (GRCm38)	missense	probably damaging	1.00
R7600:Dst	UTSW	1	34,266,930 (GRCm38)	missense	probably damaging	1.00
R7619:Dst	UTSW	1	34,199,428 (GRCm38)	missense	probably benign	0.02
R7623:Dst	UTSW	1	34,170,436 (GRCm38)	missense	probably damaging	0.99
R7649:Dst	UTSW	1	34,167,697 (GRCm38)	missense	probably benign	0.13
R7654:Dst	UTSW	1	34,228,978 (GRCm38)	missense	probably damaging	1.00
R7654:Dst	UTSW	1	34,228,977 (GRCm38)	missense	probably damaging	1.00
R7661:Dst	UTSW	1	34,256,353 (GRCm38)	critical splice donor site	probably null
R7667:Dst	UTSW	1	34,179,035 (GRCm38)	missense	possibly damaging	0.82
R7677:Dst	UTSW	1	34,169,322 (GRCm38)	critical splice donor site	probably null
R7698:Dst	UTSW	1	34,190,387 (GRCm38)	missense	probably benign	0.02
R7765:Dst	UTSW	1	34,275,694 (GRCm38)	missense	probably damaging	0.97
R7772:Dst	UTSW	1	34,181,388 (GRCm38)	missense	possibly damaging	0.90
R7779:Dst	UTSW	1	34,194,597 (GRCm38)	missense	probably damaging	0.99
R7791:Dst	UTSW	1	34,154,592 (GRCm38)	missense	probably damaging	0.99
R7821:Dst	UTSW	1	34,275,362 (GRCm38)	critical splice donor site	probably null
R7834:Dst	UTSW	1	34,194,105 (GRCm38)	missense	probably benign	0.22
R7935:Dst	UTSW	1	34,290,405 (GRCm38)	missense	probably damaging	1.00
R7940:Dst	UTSW	1	34,167,676 (GRCm38)	missense	possibly damaging	0.94
R7951:Dst	UTSW	1	34,201,186 (GRCm38)	missense	probably benign
R7956:Dst	UTSW	1	34,225,618 (GRCm38)	missense	probably damaging	1.00
R7970:Dst	UTSW	1	34,182,747 (GRCm38)	missense	possibly damaging	0.80
R7982:Dst	UTSW	1	34,182,540 (GRCm38)	missense	possibly damaging	0.89
R8048:Dst	UTSW	1	34,190,636 (GRCm38)	missense	probably benign	0.00
R8052:Dst	UTSW	1	34,284,363 (GRCm38)	missense	probably damaging	1.00
R8094:Dst	UTSW	1	34,188,959 (GRCm38)	missense	possibly damaging	0.76
R8116:Dst	UTSW	1	34,274,180 (GRCm38)	missense	probably benign	0.27
R8127:Dst	UTSW	1	34,178,229 (GRCm38)	missense	probably damaging	1.00
R8139:Dst	UTSW	1	34,191,852 (GRCm38)	missense	probably benign
R8205:Dst	UTSW	1	34,214,604 (GRCm38)	missense	probably damaging	1.00
R8211:Dst	UTSW	1	34,212,451 (GRCm38)	missense	probably damaging	1.00
R8237:Dst	UTSW	1	34,169,793 (GRCm38)	missense	possibly damaging	0.96
R8265:Dst	UTSW	1	34,178,522 (GRCm38)	missense	probably benign	0.13
R8309:Dst	UTSW	1	34,117,511 (GRCm38)	missense	probably damaging	1.00
R8315:Dst	UTSW	1	34,284,420 (GRCm38)	critical splice donor site	probably null
R8469:Dst	UTSW	1	34,229,028 (GRCm38)	missense	probably damaging	1.00
R8474:Dst	UTSW	1	34,169,185 (GRCm38)	missense	probably damaging	1.00
R8502:Dst	UTSW	1	34,167,292 (GRCm38)	missense	probably damaging	1.00
R8534:Dst	UTSW	1	34,190,307 (GRCm38)	missense	probably benign	0.12
R8535:Dst	UTSW	1	34,186,001 (GRCm38)	missense	probably damaging	1.00
R8536:Dst	UTSW	1	34,197,246 (GRCm38)	missense	possibly damaging	0.64
R8542:Dst	UTSW	1	34,192,607 (GRCm38)	missense	possibly damaging	0.61
R8560:Dst	UTSW	1	34,268,889 (GRCm38)	missense	probably damaging	1.00
R8737:Dst	UTSW	1	34,228,669 (GRCm38)	missense	probably benign	0.00
R8742:Dst	UTSW	1	34,212,344 (GRCm38)	missense	probably benign	0.01
R8882:Dst	UTSW	1	34,200,924 (GRCm38)	missense	probably damaging	1.00
R8894:Dst	UTSW	1	34,174,133 (GRCm38)	missense	possibly damaging	0.96
R8973:Dst	UTSW	1	34,228,855 (GRCm38)	missense	probably damaging	1.00
R8977:Dst	UTSW	1	34,247,783 (GRCm38)	missense	probably damaging	0.99
R8985:Dst	UTSW	1	34,249,805 (GRCm38)	missense	probably benign	0.00
R9001:Dst	UTSW	1	34,174,211 (GRCm38)	missense	possibly damaging	0.63
R9005:Dst	UTSW	1	34,228,693 (GRCm38)	missense	probably damaging	0.99
R9013:Dst	UTSW	1	34,178,084 (GRCm38)	missense	possibly damaging	0.46
R9015:Dst	UTSW	1	34,287,256 (GRCm38)	missense	probably benign	0.00
R9018:Dst	UTSW	1	34,196,059 (GRCm38)	missense	probably damaging	0.97
R9023:Dst	UTSW	1	34,114,024 (GRCm38)	critical splice donor site	probably null
R9025:Dst	UTSW	1	34,188,504 (GRCm38)	missense	possibly damaging	0.73
R9052:Dst	UTSW	1	34,197,330 (GRCm38)	nonsense	probably null
R9052:Dst	UTSW	1	34,166,964 (GRCm38)	missense	probably damaging	1.00
R9147:Dst	UTSW	1	34,189,068 (GRCm38)	missense	probably damaging	0.99
R9169:Dst	UTSW	1	34,264,571 (GRCm38)	missense	probably damaging	1.00
R9181:Dst	UTSW	1	34,192,737 (GRCm38)	missense	probably benign
R9224:Dst	UTSW	1	34,291,798 (GRCm38)	missense	probably damaging	1.00
R9245:Dst	UTSW	1	34,189,862 (GRCm38)	missense	probably benign
R9267:Dst	UTSW	1	34,193,064 (GRCm38)	missense	probably benign
R9302:Dst	UTSW	1	34,225,555 (GRCm38)	missense	probably damaging	1.00
R9344:Dst	UTSW	1	34,181,595 (GRCm38)	missense	probably damaging	0.99
R9363:Dst	UTSW	1	34,195,979 (GRCm38)	missense	probably damaging	1.00
R9441:Dst	UTSW	1	34,199,351 (GRCm38)	missense	probably damaging	1.00
R9477:Dst	UTSW	1	34,166,211 (GRCm38)	missense	probably damaging	1.00
R9501:Dst	UTSW	1	34,188,768 (GRCm38)	missense	probably damaging	0.98
R9509:Dst	UTSW	1	33,908,384 (GRCm38)	missense	possibly damaging	0.72
R9572:Dst	UTSW	1	34,211,171 (GRCm38)	missense	probably damaging	1.00
R9598:Dst	UTSW	1	34,113,933 (GRCm38)	missense	possibly damaging	0.79
R9651:Dst	UTSW	1	34,180,377 (GRCm38)	missense	probably benign	0.39
R9652:Dst	UTSW	1	34,180,377 (GRCm38)	missense	probably benign	0.39
R9664:Dst	UTSW	1	34,181,655 (GRCm38)	missense	probably benign	0.33
R9666:Dst	UTSW	1	34,179,866 (GRCm38)	nonsense	probably null
R9707:Dst	UTSW	1	34,189,853 (GRCm38)	missense	probably benign	0.28
R9721:Dst	UTSW	1	34,192,785 (GRCm38)	missense	probably benign
R9727:Dst	UTSW	1	34,275,796 (GRCm38)	missense	probably damaging	1.00
R9781:Dst	UTSW	1	34,178,994 (GRCm38)	missense	probably benign
R9787:Dst	UTSW	1	34,180,443 (GRCm38)	missense	probably benign	0.02
RF014:Dst	UTSW	1	34,247,679 (GRCm38)	missense	probably benign	0.00
X0026:Dst	UTSW	1	34,213,055 (GRCm38)	missense	probably damaging	0.97
X0028:Dst	UTSW	1	34,192,199 (GRCm38)	missense	probably damaging	1.00
X0063:Dst	UTSW	1	34,195,895 (GRCm38)	missense	probably damaging	1.00
X0066:Dst	UTSW	1	34,275,703 (GRCm38)	nonsense	probably null
Z1176:Dst	UTSW	1	34,244,445 (GRCm38)	missense	probably benign	0.02
Z1176:Dst	UTSW	1	34,188,467 (GRCm38)	nonsense	probably null
Z1176:Dst	UTSW	1	34,165,143 (GRCm38)	missense	probably benign	0.00
Z1176:Dst	UTSW	1	34,275,208 (GRCm38)	missense	probably damaging	1.00
Z1177:Dst	UTSW	1	34,194,518 (GRCm38)	missense	probably damaging	0.99
Z1177:Dst	UTSW	1	34,181,232 (GRCm38)	missense	probably benign	0.15

Predicted Primers

PCR Primer
(F):5'- AGAAAAGGCCCCTCATTCTTC -3'
(R):5'- CTCAGTAAAGGCACACGATAATTG -3'

Sequencing Primer
(F):5'- AAGGCCCCTCATTCTTCAAATTCAG -3'
(R):5'- GGCACACGATAATTGACACAGTTCAG -3'

Posted On

2018-05-24