Mutagenetix > Incidental Mutation

Incidental Mutation 'R6429:Rreb1'

518444

Institutional Source

Beutler Lab

Gene Symbol

Rreb1

Ensembl Gene

ENSMUSG00000039087

Gene Name

ras responsive element binding protein 1

Synonyms

1110037N09Rik, B930013M22Rik

MMRRC Submission

044567-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.953) question?

Stock #

R6429 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

37778400-37952005 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to G at 37932129 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Alanine at position 1155 (S1155A)

Ref Sequence

ENSEMBL: ENSMUSP00000121211 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000037232] [ENSMUST00000110237] [ENSMUST00000110238] [ENSMUST00000124373] [ENSMUST00000128570] [ENSMUST00000149745]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000037232
AA Change: S1155A

PolyPhen 2 Score 0.029 (Sensitivity: 0.95; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000049265
Gene: ENSMUSG00000039087
AA Change: S1155A

Domain	Start	End	E-Value	Type
ZnF_C2H2	66	88	5.14e-3	SMART
ZnF_C2H2	97	119	6.42e-4	SMART
ZnF_C2H2	125	147	3.49e-5	SMART
low complexity region	156	175	N/A	INTRINSIC
ZnF_C2H2	206	228	1.01e-1	SMART
ZnF_C2H2	233	256	3.78e-1	SMART
ZnF_C2H2	314	336	2.05e-2	SMART
ZnF_C2H2	641	663	2.71e-2	SMART
ZnF_C2H2	669	691	2.27e-4	SMART
ZnF_C2H2	697	720	5.81e-2	SMART
ZnF_C2H2	751	773	9.44e-2	SMART
ZnF_C2H2	788	811	2.14e0	SMART
low complexity region	916	927	N/A	INTRINSIC
low complexity region	968	977	N/A	INTRINSIC
low complexity region	995	1003	N/A	INTRINSIC
low complexity region	1032	1062	N/A	INTRINSIC
low complexity region	1071	1083	N/A	INTRINSIC
low complexity region	1119	1146	N/A	INTRINSIC
low complexity region	1154	1171	N/A	INTRINSIC
ZnF_C2H2	1251	1273	1.5e-4	SMART
ZnF_C2H2	1279	1302	1.01e-1	SMART
low complexity region	1324	1339	N/A	INTRINSIC
low complexity region	1370	1403	N/A	INTRINSIC
ZnF_C2H2	1454	1476	6.13e-1	SMART
low complexity region	1501	1516	N/A	INTRINSIC
low complexity region	1535	1548	N/A	INTRINSIC
ZnF_C2H2	1574	1596	2.24e-3	SMART
ZnF_C2H2	1602	1624	4.47e-3	SMART
low complexity region	1636	1651	N/A	INTRINSIC
low complexity region	1692	1714	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000110237
AA Change: S1155A

PolyPhen 2 Score 0.029 (Sensitivity: 0.95; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000105866
Gene: ENSMUSG00000039087
AA Change: S1155A

Domain	Start	End	E-Value	Type
ZnF_C2H2	66	88	5.14e-3	SMART
ZnF_C2H2	97	119	6.42e-4	SMART
ZnF_C2H2	125	147	3.49e-5	SMART
low complexity region	156	175	N/A	INTRINSIC
ZnF_C2H2	206	228	1.01e-1	SMART
ZnF_C2H2	233	256	3.78e-1	SMART
ZnF_C2H2	314	336	2.05e-2	SMART
ZnF_C2H2	641	663	2.71e-2	SMART
ZnF_C2H2	669	691	2.27e-4	SMART
ZnF_C2H2	697	720	5.81e-2	SMART
ZnF_C2H2	751	773	9.44e-2	SMART
ZnF_C2H2	788	811	2.14e0	SMART
low complexity region	916	927	N/A	INTRINSIC
low complexity region	968	977	N/A	INTRINSIC
low complexity region	995	1003	N/A	INTRINSIC
low complexity region	1032	1062	N/A	INTRINSIC
low complexity region	1071	1083	N/A	INTRINSIC
low complexity region	1119	1146	N/A	INTRINSIC
low complexity region	1154	1171	N/A	INTRINSIC
ZnF_C2H2	1251	1273	1.5e-4	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000110238
AA Change: S1155A

PolyPhen 2 Score 0.029 (Sensitivity: 0.95; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000105867
Gene: ENSMUSG00000039087
AA Change: S1155A

Domain	Start	End	E-Value	Type
ZnF_C2H2	66	88	5.14e-3	SMART
ZnF_C2H2	97	119	6.42e-4	SMART
ZnF_C2H2	125	147	3.49e-5	SMART
low complexity region	156	175	N/A	INTRINSIC
ZnF_C2H2	206	228	1.01e-1	SMART
ZnF_C2H2	233	256	3.78e-1	SMART
ZnF_C2H2	314	336	2.05e-2	SMART
ZnF_C2H2	641	663	2.71e-2	SMART
ZnF_C2H2	669	691	2.27e-4	SMART
ZnF_C2H2	697	720	5.81e-2	SMART
ZnF_C2H2	751	773	9.44e-2	SMART
ZnF_C2H2	788	811	2.14e0	SMART
low complexity region	916	927	N/A	INTRINSIC
low complexity region	968	977	N/A	INTRINSIC
low complexity region	995	1003	N/A	INTRINSIC
low complexity region	1032	1062	N/A	INTRINSIC
low complexity region	1071	1083	N/A	INTRINSIC
low complexity region	1119	1146	N/A	INTRINSIC
low complexity region	1154	1171	N/A	INTRINSIC
ZnF_C2H2	1251	1273	1.5e-4	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000124268

Predicted Effect

probably benign
Transcript: ENSMUST00000124373

Predicted Effect

probably benign
Transcript: ENSMUST00000128570
AA Change: S1155A

PolyPhen 2 Score 0.029 (Sensitivity: 0.95; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000115599
Gene: ENSMUSG00000039087
AA Change: S1155A

Domain	Start	End	E-Value	Type
ZnF_C2H2	66	88	5.14e-3	SMART
ZnF_C2H2	97	119	6.42e-4	SMART
ZnF_C2H2	125	147	3.49e-5	SMART
low complexity region	156	175	N/A	INTRINSIC
ZnF_C2H2	206	228	1.01e-1	SMART
ZnF_C2H2	233	256	3.78e-1	SMART
ZnF_C2H2	314	336	2.05e-2	SMART
ZnF_C2H2	641	663	2.71e-2	SMART
ZnF_C2H2	669	691	2.27e-4	SMART
ZnF_C2H2	697	720	5.81e-2	SMART
ZnF_C2H2	751	773	9.44e-2	SMART
ZnF_C2H2	788	811	2.14e0	SMART
low complexity region	916	927	N/A	INTRINSIC
low complexity region	968	977	N/A	INTRINSIC
low complexity region	995	1003	N/A	INTRINSIC
low complexity region	1032	1062	N/A	INTRINSIC
low complexity region	1071	1083	N/A	INTRINSIC
low complexity region	1119	1146	N/A	INTRINSIC
low complexity region	1154	1171	N/A	INTRINSIC
ZnF_C2H2	1251	1273	1.5e-4	SMART
ZnF_C2H2	1279	1302	1.01e-1	SMART
low complexity region	1324	1339	N/A	INTRINSIC
low complexity region	1370	1403	N/A	INTRINSIC
ZnF_C2H2	1454	1476	6.13e-1	SMART
low complexity region	1501	1516	N/A	INTRINSIC
low complexity region	1535	1548	N/A	INTRINSIC
ZnF_C2H2	1574	1596	2.24e-3	SMART
ZnF_C2H2	1602	1624	4.47e-3	SMART
low complexity region	1636	1651	N/A	INTRINSIC
low complexity region	1692	1714	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000149745
AA Change: S1155A

PolyPhen 2 Score 0.029 (Sensitivity: 0.95; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000121211
Gene: ENSMUSG00000039087
AA Change: S1155A

Domain	Start	End	E-Value	Type
ZnF_C2H2	66	88	5.14e-3	SMART
ZnF_C2H2	97	119	6.42e-4	SMART
ZnF_C2H2	125	147	3.49e-5	SMART
low complexity region	156	175	N/A	INTRINSIC
ZnF_C2H2	206	228	1.01e-1	SMART
ZnF_C2H2	233	256	3.78e-1	SMART
ZnF_C2H2	314	336	2.05e-2	SMART
ZnF_C2H2	641	663	2.71e-2	SMART
ZnF_C2H2	669	691	2.27e-4	SMART
ZnF_C2H2	697	720	5.81e-2	SMART
ZnF_C2H2	751	773	9.44e-2	SMART
ZnF_C2H2	788	811	2.14e0	SMART
low complexity region	916	927	N/A	INTRINSIC
low complexity region	968	977	N/A	INTRINSIC
low complexity region	995	1003	N/A	INTRINSIC
low complexity region	1032	1062	N/A	INTRINSIC
low complexity region	1071	1083	N/A	INTRINSIC
low complexity region	1119	1146	N/A	INTRINSIC
low complexity region	1154	1171	N/A	INTRINSIC
ZnF_C2H2	1251	1273	1.5e-4	SMART

Coding Region Coverage

1x: 99.9%
3x: 99.5%
10x: 97.6%
20x: 92.6%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Allele List at MGI

Other mutations in this stock

Total: 53 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acacb	G	A	5: 114,228,591 (GRCm38)	E1565K	probably damaging	Het
Amy1	T	C	3: 113,569,509 (GRCm38)	N63S	probably damaging	Het
Arhgef15	G	T	11: 68,947,796 (GRCm38)	N591K	probably damaging	Het
AW551984	A	G	9: 39,600,614 (GRCm38)	S34P	probably damaging	Het
C2cd3	A	G	7: 100,432,091 (GRCm38)	D127G	probably damaging	Het
Ccdc87	T	A	19: 4,841,235 (GRCm38)	V585E	probably benign	Het
Cemip2	T	C	19: 21,801,908 (GRCm38)	C361R	probably benign	Het
Cul2	T	C	18: 3,421,345 (GRCm38)	I223T	probably damaging	Het
Dgkq	C	T	5: 108,653,708 (GRCm38)	V495M	probably damaging	Het
Dpp10	A	G	1: 123,367,601 (GRCm38)	I570T	possibly damaging	Het
Dstyk	C	T	1: 132,449,804 (GRCm38)	Q383*	probably null	Het
Emilin2	C	A	17: 71,310,956 (GRCm38)		probably benign	Het
Fnip1	A	G	11: 54,515,567 (GRCm38)	I1163M	probably damaging	Het
Fryl	C	T	5: 73,090,751 (GRCm38)	E1008K	possibly damaging	Het
Gm35315	A	T	5: 110,078,659 (GRCm38)	Y305N	possibly damaging	Het
Grhl3	T	A	4: 135,557,196 (GRCm38)	D195V	probably damaging	Het
Ift56	T	A	6: 38,398,313 (GRCm38)	S250T	possibly damaging	Het
Il33	T	C	19: 29,952,000 (GRCm38)	F41S	probably benign	Het
Il4	A	G	11: 53,613,909 (GRCm38)	S15P	possibly damaging	Het
Inf2	C	T	12: 112,604,256 (GRCm38)	P410S	probably benign	Het
Kalrn	T	A	16: 34,332,164 (GRCm38)	D349V	possibly damaging	Het
Krt4	A	G	15: 101,922,794 (GRCm38)	M224T	probably benign	Het
Lrp2	C	T	2: 69,461,287 (GRCm38)	S3516N	probably damaging	Het
Macf1	A	T	4: 123,401,594 (GRCm38)		probably null	Het
Msr1	G	A	8: 39,615,817 (GRCm38)	P213S	probably damaging	Het
Nptx1	G	T	11: 119,544,721 (GRCm38)	C256*	probably null	Het
Nr1d1	T	C	11: 98,772,014 (GRCm38)	Y51C	probably damaging	Het
Or4c11c	G	A	2: 88,831,525 (GRCm38)	R136Q	probably benign	Het
Panx3	T	C	9: 37,661,165 (GRCm38)	D363G	probably damaging	Het
Pira13	A	T	7: 3,822,346 (GRCm38)	H432Q	possibly damaging	Het
Prkag1	A	G	15: 98,814,523 (GRCm38)	F143L	probably damaging	Het
Ptger4	T	C	15: 5,242,997 (GRCm38)	K72R	possibly damaging	Het
Pvrig	A	G	5: 138,342,050 (GRCm38)	T28A	probably benign	Het
Rhod	C	T	19: 4,426,105 (GRCm38)	C206Y	probably benign	Het
Rngtt	C	A	4: 33,320,606 (GRCm38)	S51*	probably null	Het
Scn9a	A	C	2: 66,526,963 (GRCm38)	I998S	possibly damaging	Het
Sfmbt1	T	A	14: 30,773,911 (GRCm38)	F50L	probably damaging	Het
Six4	A	T	12: 73,103,473 (GRCm38)	V766D	probably damaging	Het
Smpd1	T	C	7: 105,556,928 (GRCm38)	I421T	probably damaging	Het
Son	T	A	16: 91,658,166 (GRCm38)	M1267K	probably benign	Het
Styk1	T	A	6: 131,310,064 (GRCm38)	D156V	possibly damaging	Het
Supt3	A	G	17: 45,119,143 (GRCm38)	E361G	probably benign	Het
Tbx3	T	A	5: 119,674,191 (GRCm38)	Y185*	probably null	Het
Trpm1	A	T	7: 64,268,504 (GRCm38)	T531S	probably benign	Het
Tspan32	T	A	7: 143,018,742 (GRCm38)	W172R	possibly damaging	Het
Urb1	A	T	16: 90,762,430 (GRCm38)		probably null	Het
Vmn2r70	T	A	7: 85,559,068 (GRCm38)	I734F	probably damaging	Het
Vwa7	A	G	17: 35,024,199 (GRCm38)	T618A	probably benign	Het
Wac	T	A	18: 7,920,163 (GRCm38)	V339E	probably damaging	Het
Wrn	G	A	8: 33,342,996 (GRCm38)	T156M	probably damaging	Het
Zeb1	T	A	18: 5,770,498 (GRCm38)	C884S	probably damaging	Het
Zfp747l1	T	C	7: 127,385,042 (GRCm38)		probably benign	Het
Zmpste24	A	G	4: 121,095,670 (GRCm38)	V10A	probably damaging	Het

Other mutations in Rreb1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00321:Rreb1	APN	13	37,916,496 (GRCm38)	missense	probably benign	0.09
IGL00336:Rreb1	APN	13	37,929,646 (GRCm38)	nonsense	probably null
IGL00473:Rreb1	APN	13	37,930,791 (GRCm38)	nonsense	probably null
IGL01338:Rreb1	APN	13	37,931,034 (GRCm38)	missense	probably damaging	1.00
IGL01836:Rreb1	APN	13	37,931,457 (GRCm38)	missense	probably damaging	1.00
IGL02066:Rreb1	APN	13	37,931,506 (GRCm38)	missense	probably benign	0.16
IGL02661:Rreb1	APN	13	37,930,802 (GRCm38)	nonsense	probably null
IGL02739:Rreb1	APN	13	37,893,821 (GRCm38)	missense	probably damaging	1.00
IGL03267:Rreb1	APN	13	37,932,193 (GRCm38)	missense	probably benign	0.30
IGL03332:Rreb1	APN	13	37,930,916 (GRCm38)	missense	probably benign	0.42
IGL03403:Rreb1	APN	13	37,929,574 (GRCm38)	missense	possibly damaging	0.78
R0039:Rreb1	UTSW	13	37,899,637 (GRCm38)	missense	probably damaging	1.00
R0039:Rreb1	UTSW	13	37,899,637 (GRCm38)	missense	probably damaging	1.00
R0101:Rreb1	UTSW	13	37,931,542 (GRCm38)	missense	probably benign	0.04
R0265:Rreb1	UTSW	13	37,916,155 (GRCm38)	nonsense	probably null
R0635:Rreb1	UTSW	13	37,941,564 (GRCm38)	missense	possibly damaging	0.92
R0939:Rreb1	UTSW	13	37,932,231 (GRCm38)	missense	probably benign	0.09
R1099:Rreb1	UTSW	13	37,948,891 (GRCm38)	missense	probably benign	0.16
R1438:Rreb1	UTSW	13	37,930,605 (GRCm38)	missense	probably benign	0.16
R1457:Rreb1	UTSW	13	37,946,928 (GRCm38)	missense	possibly damaging	0.52
R1510:Rreb1	UTSW	13	37,931,884 (GRCm38)	missense	probably benign	0.04
R1672:Rreb1	UTSW	13	37,930,537 (GRCm38)	missense	probably benign	0.09
R1772:Rreb1	UTSW	13	37,930,923 (GRCm38)	missense	probably benign	0.09
R2171:Rreb1	UTSW	13	37,930,846 (GRCm38)	missense	probably benign	0.00
R2371:Rreb1	UTSW	13	37,916,537 (GRCm38)	missense	probably benign	0.09
R2566:Rreb1	UTSW	13	37,929,792 (GRCm38)	missense	possibly damaging	0.62
R2571:Rreb1	UTSW	13	37,899,637 (GRCm38)	missense	probably damaging	1.00
R2862:Rreb1	UTSW	13	37,932,453 (GRCm38)	missense	probably benign	0.02
R2874:Rreb1	UTSW	13	37,916,508 (GRCm38)	missense	probably benign	0.09
R2911:Rreb1	UTSW	13	37,948,920 (GRCm38)	missense	probably benign	0.00
R3722:Rreb1	UTSW	13	37,947,098 (GRCm38)	missense	probably benign	0.01
R3767:Rreb1	UTSW	13	37,929,603 (GRCm38)	missense	possibly damaging	0.95
R3770:Rreb1	UTSW	13	37,929,603 (GRCm38)	missense	possibly damaging	0.95
R3885:Rreb1	UTSW	13	37,893,965 (GRCm38)	missense	probably damaging	1.00
R3886:Rreb1	UTSW	13	37,898,506 (GRCm38)	splice site	probably null
R3887:Rreb1	UTSW	13	37,893,965 (GRCm38)	missense	probably damaging	1.00
R3888:Rreb1	UTSW	13	37,893,965 (GRCm38)	missense	probably damaging	1.00
R3889:Rreb1	UTSW	13	37,893,965 (GRCm38)	missense	probably damaging	1.00
R4064:Rreb1	UTSW	13	37,930,317 (GRCm38)	missense	probably benign	0.42
R4134:Rreb1	UTSW	13	37,947,123 (GRCm38)	missense	probably damaging	1.00
R4135:Rreb1	UTSW	13	37,947,123 (GRCm38)	missense	probably damaging	1.00
R4174:Rreb1	UTSW	13	37,930,150 (GRCm38)	missense	possibly damaging	0.95
R4250:Rreb1	UTSW	13	37,893,893 (GRCm38)	missense	possibly damaging	0.63
R4287:Rreb1	UTSW	13	37,931,931 (GRCm38)	missense	probably benign	0.03
R4396:Rreb1	UTSW	13	37,930,443 (GRCm38)	nonsense	probably null
R4658:Rreb1	UTSW	13	37,948,801 (GRCm38)	missense	probably damaging	1.00
R4841:Rreb1	UTSW	13	37,916,526 (GRCm38)	missense	probably benign	0.09
R4856:Rreb1	UTSW	13	37,931,058 (GRCm38)	missense	possibly damaging	0.62
R4886:Rreb1	UTSW	13	37,931,058 (GRCm38)	missense	possibly damaging	0.62
R5092:Rreb1	UTSW	13	37,928,278 (GRCm38)	missense	probably benign	0.09
R5122:Rreb1	UTSW	13	37,930,768 (GRCm38)	missense	probably benign	0.02
R5405:Rreb1	UTSW	13	37,949,111 (GRCm38)	missense	probably damaging	0.99
R5408:Rreb1	UTSW	13	37,931,344 (GRCm38)	missense	probably benign	0.01
R5446:Rreb1	UTSW	13	37,898,497 (GRCm38)	missense	possibly damaging	0.78
R5641:Rreb1	UTSW	13	37,947,421 (GRCm38)	missense	probably benign	0.00
R5859:Rreb1	UTSW	13	37,947,409 (GRCm38)	missense	probably benign	0.06
R5859:Rreb1	UTSW	13	37,947,408 (GRCm38)	missense	probably benign	0.24
R6678:Rreb1	UTSW	13	37,899,699 (GRCm38)	missense	probably damaging	1.00
R7130:Rreb1	UTSW	13	37,899,748 (GRCm38)	missense	probably damaging	1.00
R7186:Rreb1	UTSW	13	37,941,632 (GRCm38)	missense	probably benign	0.02
R7188:Rreb1	UTSW	13	37,916,568 (GRCm38)	missense	possibly damaging	0.79
R7387:Rreb1	UTSW	13	37,947,064 (GRCm38)	missense	unknown
R7453:Rreb1	UTSW	13	37,941,569 (GRCm38)	missense	probably damaging	0.98
R7492:Rreb1	UTSW	13	37,931,748 (GRCm38)	missense	probably benign	0.00
R7585:Rreb1	UTSW	13	37,893,898 (GRCm38)	missense	probably benign	0.07
R7621:Rreb1	UTSW	13	37,949,066 (GRCm38)	missense
R7645:Rreb1	UTSW	13	37,931,034 (GRCm38)	missense	probably damaging	1.00
R7653:Rreb1	UTSW	13	37,930,386 (GRCm38)	missense	probably benign	0.19
R7670:Rreb1	UTSW	13	37,931,572 (GRCm38)	missense	probably benign	0.00
R7701:Rreb1	UTSW	13	37,930,116 (GRCm38)	missense	possibly damaging	0.60
R7708:Rreb1	UTSW	13	37,929,570 (GRCm38)	missense	probably benign	0.18
R7874:Rreb1	UTSW	13	37,947,124 (GRCm38)	missense	probably damaging	1.00
R8103:Rreb1	UTSW	13	37,941,701 (GRCm38)	missense	probably benign	0.16
R8129:Rreb1	UTSW	13	37,929,799 (GRCm38)	missense	probably benign	0.00
R8239:Rreb1	UTSW	13	37,893,872 (GRCm38)	missense	probably damaging	1.00
R8324:Rreb1	UTSW	13	37,947,621 (GRCm38)	missense	probably damaging	1.00
R8824:Rreb1	UTSW	13	37,930,516 (GRCm38)	missense	probably damaging	0.99
R8910:Rreb1	UTSW	13	37,948,765 (GRCm38)	missense
R8992:Rreb1	UTSW	13	37,930,376 (GRCm38)	missense	probably benign	0.30
R9064:Rreb1	UTSW	13	37,931,350 (GRCm38)	missense	possibly damaging	0.94
R9087:Rreb1	UTSW	13	37,931,668 (GRCm38)	missense	probably benign	0.33
R9130:Rreb1	UTSW	13	37,930,306 (GRCm38)	missense	probably benign	0.29
R9582:Rreb1	UTSW	13	37,930,758 (GRCm38)	missense	probably benign	0.29
R9602:Rreb1	UTSW	13	37,930,501 (GRCm38)	missense	probably damaging	0.99
R9774:Rreb1	UTSW	13	37,930,209 (GRCm38)	missense	probably benign	0.18
X0024:Rreb1	UTSW	13	37,931,580 (GRCm38)	missense	probably benign	0.09
X0026:Rreb1	UTSW	13	37,931,992 (GRCm38)	missense	probably benign	0.17
Z1088:Rreb1	UTSW	13	37,948,937 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- CAAAGCCCTCGATGACAGAG -3'
(R):5'- CTGAGTGTCATCCTCTGCAG -3'

Sequencing Primer
(F):5'- CCTACTCTGCTGAAAACGAAGGTAG -3'
(R):5'- GTCTGCAGAAAGGGACTGAACTTG -3'

Posted On

2018-05-24