Incidental Mutation 'IGL01066:Nlrp4g'
ID 51859
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Nlrp4g
Ensembl Gene ENSMUSG00000079741
Gene Name NLR family, pyrin domain containing 4G
Synonyms nalp4g
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.085) question?
Stock # IGL01066
Quality Score
Status
Chromosome 9
Chromosomal Location 124348831-124354028 bp(+) (GRCm38)
Type of Mutation unclassified
DNA Base Change (assembly) C to A at 124349526 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
AlphaFold no structure available at present
Predicted Effect noncoding transcript
Transcript: ENSMUST00000067621
SMART Domains Protein: ENSMUSP00000065508
Gene: ENSMUSG00000079741

DomainStartEndE-ValueType
Pfam:NACHT 69 238 1.5e-39 PFAM
Blast:LRR 555 582 9e-10 BLAST
Blast:LRR 610 637 7e-10 BLAST
Predicted Effect noncoding transcript
Transcript: ENSMUST00000214229
Predicted Effect noncoding transcript
Transcript: ENSMUST00000215276
Predicted Effect noncoding transcript
Transcript: ENSMUST00000215602
Predicted Effect noncoding transcript
Transcript: ENSMUST00000216416
Predicted Effect noncoding transcript
Transcript: ENSMUST00000217178
Predicted Effect noncoding transcript
Transcript: ENSMUST00000217183
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 58 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1110038F14Rik G A 15: 76,950,275 V124I probably damaging Het
2300003K06Rik T A 11: 99,837,628 R130* probably null Het
9030624J02Rik T A 7: 118,773,011 probably null Het
Abca12 T A 1: 71,353,730 R117W possibly damaging Het
Agrn A G 4: 156,177,343 S497P probably benign Het
Alpk1 A T 3: 127,680,225 S710T probably benign Het
Anapc4 T A 5: 52,857,209 N471K probably benign Het
Ano3 A T 2: 110,661,445 M879K probably null Het
Apoe A G 7: 19,696,600 L239P probably damaging Het
Ash1l T C 3: 88,984,635 Y1274H probably damaging Het
B3glct C T 5: 149,709,425 T80I possibly damaging Het
Casc1 C T 6: 145,176,222 G624S probably damaging Het
Ccdc146 T C 5: 21,319,542 T271A probably benign Het
Chd8 T A 14: 52,217,766 N1088I probably damaging Het
Csnk1g2 T C 10: 80,634,647 probably benign Het
Daxx T A 17: 33,913,893 V627D probably benign Het
Dpy19l3 A G 7: 35,692,767 probably benign Het
Enc1 A G 13: 97,245,314 I111V probably benign Het
Ep400 A G 5: 110,668,199 probably benign Het
Fig4 T C 10: 41,285,417 probably benign Het
Fkbp7 A T 2: 76,672,908 L36* probably null Het
Fxn A T 19: 24,267,298 probably benign Het
Gm10152 C T 7: 144,763,256 P16L unknown Het
Hivep2 T C 10: 14,149,024 V2194A possibly damaging Het
Hook3 T G 8: 26,048,298 E525A probably damaging Het
Icam1 A G 9: 21,016,105 probably null Het
Ifngr1 C T 10: 19,609,198 T315I probably damaging Het
Igsf10 A G 3: 59,327,782 probably null Het
Krt87 A G 15: 101,438,385 probably null Het
Lama1 T A 17: 67,743,326 C311S probably damaging Het
Lig3 T A 11: 82,797,315 M714K possibly damaging Het
Lrmp T C 6: 145,160,955 S222P probably damaging Het
Lypd5 C T 7: 24,353,485 T189I probably benign Het
Mapk8ip3 C T 17: 24,901,718 G807D probably benign Het
Met T C 6: 17,535,105 probably null Het
Nlrp6 T A 7: 140,921,796 V62D possibly damaging Het
Nme7 A G 1: 164,345,430 probably null Het
Olfr1034 A G 2: 86,047,258 R259G probably damaging Het
Olfr1392 T C 11: 49,293,630 I103T possibly damaging Het
Olfr507 T C 7: 108,621,857 F15S probably damaging Het
Pcnx G A 12: 81,992,021 R2020Q possibly damaging Het
Pdzd2 T A 15: 12,402,632 probably benign Het
Pi4ka A G 16: 17,348,773 probably benign Het
Pkdrej T G 15: 85,816,159 I1859L probably benign Het
Plcg1 A T 2: 160,754,398 H638L probably damaging Het
Polr1b C T 2: 129,119,152 S677L probably damaging Het
Ppef2 A G 5: 92,234,237 L533P probably damaging Het
Sh3rf1 T A 8: 61,329,336 W171R probably damaging Het
Son T C 16: 91,660,136 probably benign Het
Sycp1 A G 3: 102,920,634 S266P probably damaging Het
Tedc1 A G 12: 113,163,150 E344G probably damaging Het
Tkfc T C 19: 10,594,528 I381M probably benign Het
Tmprss6 T C 15: 78,442,434 D1G probably null Het
Ttn T C 2: 76,752,426 T22708A probably damaging Het
Ubtf T C 11: 102,308,884 probably benign Het
Vwc2l T C 1: 70,728,911 F45L probably damaging Het
Xpo7 T C 14: 70,701,755 T154A probably benign Het
Yars2 C T 16: 16,306,542 R338* probably null Het
Other mutations in Nlrp4g
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01087:Nlrp4g APN 9 124353858 critical splice acceptor site noncoding transcript
IGL01106:Nlrp4g APN 9 124350452 unclassified noncoding transcript
IGL01938:Nlrp4g APN 9 124349068 unclassified noncoding transcript
IGL02088:Nlrp4g APN 9 124350453 unclassified noncoding transcript
IGL02170:Nlrp4g APN 9 124348980 unclassified noncoding transcript
IGL02582:Nlrp4g APN 9 124349764 unclassified noncoding transcript
IGL02588:Nlrp4g APN 9 124348843 unclassified noncoding transcript
IGL02931:Nlrp4g APN 9 124348940 unclassified noncoding transcript
IGL03111:Nlrp4g APN 9 124353978 exon noncoding transcript
IGL03373:Nlrp4g APN 9 124349853 unclassified noncoding transcript
R0617:Nlrp4g UTSW 9 124349540 unclassified noncoding transcript
R1419:Nlrp4g UTSW 9 124349434 unclassified noncoding transcript
R2060:Nlrp4g UTSW 9 124349693 unclassified noncoding transcript
R2152:Nlrp4g UTSW 9 124353339 exon noncoding transcript
R2356:Nlrp4g UTSW 9 124349306 unclassified noncoding transcript
R2384:Nlrp4g UTSW 9 124349707 unclassified noncoding transcript
R2698:Nlrp4g UTSW 9 124349630 unclassified noncoding transcript
R3878:Nlrp4g UTSW 9 124349362 unclassified noncoding transcript
R4640:Nlrp4g UTSW 9 124349153 unclassified noncoding transcript
R4745:Nlrp4g UTSW 9 124349515 unclassified noncoding transcript
R4754:Nlrp4g UTSW 9 124349788 unclassified noncoding transcript
R4937:Nlrp4g UTSW 9 124354005 exon noncoding transcript
R5024:Nlrp4g UTSW 9 124350155 unclassified noncoding transcript
R5162:Nlrp4g UTSW 9 124350394 unclassified noncoding transcript
R5407:Nlrp4g UTSW 9 124349930 unclassified noncoding transcript
R5521:Nlrp4g UTSW 9 124350020 unclassified noncoding transcript
R8224:Nlrp4g UTSW 9 124353374 missense noncoding transcript
R8259:Nlrp4g UTSW 9 124353392 missense noncoding transcript
Z1088:Nlrp4g UTSW 9 124349201 unclassified noncoding transcript
Posted On 2013-06-21