Incidental Mutation 'R6257:Chd1'
| ID |
519603 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Chd1
|
| Ensembl Gene |
ENSMUSG00000023852 |
| Gene Name |
chromodomain helicase DNA binding protein 1 |
| Synonyms |
4930525N21Rik |
| MMRRC Submission |
044374-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6257 (G1)
|
| Quality Score |
42.0073 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
15704967-15772610 bp(+) (GRCm38) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to G
at 15730203 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000134091
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000024627]
[ENSMUST00000173311]
|
| AlphaFold |
P40201 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000024627
|
| SMART Domains |
Protein: ENSMUSP00000024627
Gene: ENSMUSG00000023852
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
67 |
N/A |
INTRINSIC |
|
low complexity region
|
105 |
115 |
N/A |
INTRINSIC |
|
low complexity region
|
116 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
175 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
230 |
N/A |
INTRINSIC |
|
CHROMO
|
268 |
355 |
6.43e-20 |
SMART |
|
CHROMO
|
385 |
443 |
1.19e-14 |
SMART |
|
DEXDc
|
475 |
672 |
3.44e-34 |
SMART |
|
Blast:DEXDc
|
692 |
786 |
2e-54 |
BLAST |
|
low complexity region
|
787 |
799 |
N/A |
INTRINSIC |
|
HELICc
|
816 |
900 |
8.48e-25 |
SMART |
|
Blast:DEXDc
|
955 |
1234 |
1e-112 |
BLAST |
|
PDB:4B4C|A
|
1119 |
1320 |
1e-132 |
PDB |
|
low complexity region
|
1325 |
1348 |
N/A |
INTRINSIC |
|
low complexity region
|
1377 |
1388 |
N/A |
INTRINSIC |
|
DUF4208
|
1396 |
1500 |
5.54e-51 |
SMART |
|
low complexity region
|
1507 |
1516 |
N/A |
INTRINSIC |
|
low complexity region
|
1538 |
1549 |
N/A |
INTRINSIC |
|
low complexity region
|
1626 |
1650 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173159
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000173311
|
| SMART Domains |
Protein: ENSMUSP00000134091
Gene: ENSMUSG00000023852
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
67 |
N/A |
INTRINSIC |
|
low complexity region
|
105 |
115 |
N/A |
INTRINSIC |
|
low complexity region
|
116 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
175 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
230 |
N/A |
INTRINSIC |
|
CHROMO
|
268 |
355 |
6.43e-20 |
SMART |
|
CHROMO
|
385 |
443 |
1.19e-14 |
SMART |
|
DEXDc
|
475 |
672 |
3.44e-34 |
SMART |
|
Blast:DEXDc
|
692 |
786 |
2e-54 |
BLAST |
|
low complexity region
|
787 |
799 |
N/A |
INTRINSIC |
|
HELICc
|
816 |
900 |
8.48e-25 |
SMART |
|
Blast:DEXDc
|
955 |
1078 |
2e-38 |
BLAST |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.6%
- 20x: 96.4%
|
| Validation Efficiency |
97% (74/76) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality associated with arrest of epiblast development due to increased apoptosis and cell cycle defects, abnormal rostral-caudal axis patterning, and failure to gastrulate. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcf1 |
A |
T |
17: 35,961,182 (GRCm38) |
N313K |
probably benign |
Het |
| Adamts2 |
T |
C |
11: 50,775,326 (GRCm38) |
V383A |
probably damaging |
Het |
| Adamts6 |
A |
T |
13: 104,462,282 (GRCm38) |
Q877L |
probably benign |
Het |
| Adgre4 |
C |
T |
17: 55,802,133 (GRCm38) |
T380I |
possibly damaging |
Het |
| Aspm |
A |
G |
1: 139,482,053 (GRCm38) |
|
probably null |
Het |
| Atg16l2 |
A |
G |
7: 101,301,895 (GRCm38) |
|
probably null |
Het |
| Bcl6b |
C |
T |
11: 70,226,052 (GRCm38) |
R467H |
probably benign |
Het |
| Cacna2d4 |
G |
A |
6: 119,281,619 (GRCm38) |
|
probably null |
Het |
| Casp8ap2 |
A |
G |
4: 32,641,364 (GRCm38) |
D806G |
possibly damaging |
Het |
| Ccdc13 |
A |
G |
9: 121,798,909 (GRCm38) |
|
probably benign |
Het |
| Ccser1 |
A |
G |
6: 62,379,785 (GRCm38) |
T736A |
probably benign |
Het |
| Ccser1 |
A |
G |
6: 61,373,962 (GRCm38) |
D501G |
probably damaging |
Het |
| Cd164l2 |
T |
A |
4: 133,221,034 (GRCm38) |
C19S |
unknown |
Het |
| Cdk15 |
G |
A |
1: 59,257,105 (GRCm38) |
|
probably null |
Het |
| Cebpz |
T |
C |
17: 78,935,832 (GRCm38) |
E131G |
probably benign |
Het |
| Ces1d |
T |
C |
8: 93,166,397 (GRCm38) |
D519G |
probably benign |
Het |
| Cftr |
A |
C |
6: 18,282,501 (GRCm38) |
T1067P |
probably benign |
Het |
| Chil4 |
T |
A |
3: 106,204,096 (GRCm38) |
D234V |
possibly damaging |
Het |
| Cldn16 |
T |
A |
16: 26,481,330 (GRCm38) |
S173T |
probably damaging |
Het |
| Cpd |
A |
T |
11: 76,812,670 (GRCm38) |
F456I |
probably benign |
Het |
| Cst8 |
C |
A |
2: 148,805,445 (GRCm38) |
A125E |
probably damaging |
Het |
| Dars2 |
G |
T |
1: 161,041,828 (GRCm38) |
P617Q |
probably damaging |
Het |
| Defb26 |
A |
G |
2: 152,507,940 (GRCm38) |
V140A |
unknown |
Het |
| Dntt |
T |
G |
19: 41,053,062 (GRCm38) |
V395G |
probably damaging |
Het |
| Dock10 |
G |
A |
1: 80,503,696 (GRCm38) |
|
probably benign |
Het |
| Dscam |
T |
C |
16: 96,673,714 (GRCm38) |
N1216S |
possibly damaging |
Het |
| En1 |
A |
T |
1: 120,603,907 (GRCm38) |
D292V |
unknown |
Het |
| Erbb4 |
A |
T |
1: 68,396,273 (GRCm38) |
L155Q |
probably damaging |
Het |
| Erbin |
T |
C |
13: 103,862,288 (GRCm38) |
T197A |
probably benign |
Het |
| Fat2 |
A |
G |
11: 55,262,581 (GRCm38) |
F3602L |
probably benign |
Het |
| Fuk |
A |
T |
8: 110,890,545 (GRCm38) |
C365S |
probably benign |
Het |
| Gm3443 |
A |
T |
19: 21,555,711 (GRCm38) |
D13V |
unknown |
Het |
| Gm6401 |
T |
C |
14: 41,967,871 (GRCm38) |
Q10R |
probably benign |
Het |
| Gmcl1 |
G |
A |
6: 86,700,641 (GRCm38) |
T410I |
possibly damaging |
Het |
| Grid2ip |
G |
A |
5: 143,380,429 (GRCm38) |
S379N |
probably damaging |
Het |
| H2-T24 |
T |
A |
17: 36,014,682 (GRCm38) |
T305S |
probably benign |
Het |
| Ksr2 |
A |
T |
5: 117,414,844 (GRCm38) |
M6L |
probably benign |
Het |
| Lama2 |
A |
G |
10: 26,986,899 (GRCm38) |
L2956S |
possibly damaging |
Het |
| Lhfpl3 |
A |
G |
5: 22,746,559 (GRCm38) |
T123A |
probably benign |
Het |
| Lrp1b |
T |
A |
2: 40,596,969 (GRCm38) |
|
probably null |
Het |
| Ltn1 |
G |
A |
16: 87,411,774 (GRCm38) |
A812V |
possibly damaging |
Het |
| Maml2 |
C |
T |
9: 13,620,426 (GRCm38) |
S312L |
probably damaging |
Het |
| Myo7b |
T |
A |
18: 32,013,415 (GRCm38) |
N106Y |
probably damaging |
Het |
| Nacc2 |
A |
T |
2: 26,060,408 (GRCm38) |
C439S |
probably damaging |
Het |
| Ncoa7 |
A |
G |
10: 30,694,177 (GRCm38) |
I224T |
probably damaging |
Het |
| Nf1 |
A |
T |
11: 79,549,491 (GRCm38) |
L2303F |
probably damaging |
Het |
| Noc3l |
A |
T |
19: 38,795,905 (GRCm38) |
|
probably null |
Het |
| Nup155 |
C |
T |
15: 8,150,798 (GRCm38) |
R1120* |
probably null |
Het |
| Oas3 |
C |
A |
5: 120,761,135 (GRCm38) |
|
probably benign |
Het |
| Ocln |
T |
C |
13: 100,539,509 (GRCm38) |
I159V |
probably benign |
Het |
| Olfr315 |
T |
A |
11: 58,779,003 (GRCm38) |
V292E |
probably damaging |
Het |
| Olfr406 |
T |
C |
11: 74,270,007 (GRCm38) |
V206A |
probably damaging |
Het |
| Os9 |
A |
C |
10: 127,119,137 (GRCm38) |
C181G |
probably damaging |
Het |
| Phldb1 |
C |
T |
9: 44,696,140 (GRCm38) |
R1256Q |
probably damaging |
Het |
| Pkd1l1 |
G |
A |
11: 8,942,195 (GRCm38) |
T208I |
probably benign |
Het |
| Plppr4 |
T |
C |
3: 117,322,579 (GRCm38) |
Q485R |
possibly damaging |
Het |
| Prkcb |
T |
A |
7: 122,568,163 (GRCm38) |
D365E |
probably benign |
Het |
| Ptprz1 |
T |
A |
6: 22,959,640 (GRCm38) |
N45K |
probably damaging |
Het |
| Rbl2 |
T |
C |
8: 91,115,678 (GRCm38) |
L987P |
probably damaging |
Het |
| Runx1 |
T |
A |
16: 92,695,911 (GRCm38) |
|
probably benign |
Het |
| Sept4 |
C |
A |
11: 87,590,349 (GRCm38) |
Q372K |
probably benign |
Het |
| Slc24a4 |
A |
G |
12: 102,254,510 (GRCm38) |
E400G |
probably benign |
Het |
| Smtnl2 |
G |
A |
11: 72,401,399 (GRCm38) |
A274V |
probably damaging |
Het |
| Sri |
T |
A |
5: 8,059,596 (GRCm38) |
|
probably null |
Het |
| St3gal3 |
C |
T |
4: 118,107,678 (GRCm38) |
|
probably benign |
Het |
| Tfpt |
A |
T |
7: 3,629,567 (GRCm38) |
L3* |
probably null |
Het |
| Tgfb3 |
T |
C |
12: 86,077,841 (GRCm38) |
D31G |
possibly damaging |
Het |
| Thsd7a |
G |
T |
6: 12,408,988 (GRCm38) |
C678* |
probably null |
Het |
| Tmbim1 |
A |
G |
1: 74,293,066 (GRCm38) |
Y101H |
probably damaging |
Het |
| Tmem17 |
A |
G |
11: 22,512,297 (GRCm38) |
|
probably benign |
Het |
| Tmprss15 |
A |
T |
16: 78,972,225 (GRCm38) |
V769E |
probably damaging |
Het |
| Trak1 |
C |
T |
9: 121,446,755 (GRCm38) |
R175C |
probably damaging |
Het |
| Trak1 |
G |
T |
9: 121,367,224 (GRCm38) |
V41F |
possibly damaging |
Het |
| Trim30c |
T |
C |
7: 104,390,168 (GRCm38) |
Y140C |
probably damaging |
Het |
| Tubgcp3 |
A |
T |
8: 12,649,835 (GRCm38) |
|
probably null |
Het |
| Ubr7 |
T |
A |
12: 102,765,840 (GRCm38) |
C158* |
probably null |
Het |
| Vmn2r79 |
A |
T |
7: 87,002,570 (GRCm38) |
L392F |
probably benign |
Het |
| Zfp536 |
T |
A |
7: 37,480,405 (GRCm38) |
D925V |
probably damaging |
Het |
|
| Other mutations in Chd1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00704:Chd1
|
APN |
17 |
15,732,565 (GRCm38) |
missense |
probably benign |
0.37 |
|
IGL01356:Chd1
|
APN |
17 |
15,749,865 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01369:Chd1
|
APN |
17 |
15,754,997 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL01519:Chd1
|
APN |
17 |
17,378,569 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01604:Chd1
|
APN |
17 |
15,770,097 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL01635:Chd1
|
APN |
17 |
17,378,596 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01721:Chd1
|
APN |
17 |
15,770,168 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01959:Chd1
|
APN |
17 |
15,742,173 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02367:Chd1
|
APN |
17 |
17,390,053 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02476:Chd1
|
APN |
17 |
15,734,273 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02756:Chd1
|
APN |
17 |
15,730,807 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL02817:Chd1
|
APN |
17 |
15,749,500 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL03084:Chd1
|
APN |
17 |
15,770,298 (GRCm38) |
missense |
probably benign |
0.22 |
|
IGL03108:Chd1
|
APN |
17 |
15,725,281 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
Holly
|
UTSW |
17 |
15,726,283 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R0053:Chd1
|
UTSW |
17 |
15,747,189 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0053:Chd1
|
UTSW |
17 |
15,747,189 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0128:Chd1
|
UTSW |
17 |
17,393,567 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0197:Chd1
|
UTSW |
17 |
15,725,431 (GRCm38) |
missense |
probably benign |
|
|
R0285:Chd1
|
UTSW |
17 |
17,374,680 (GRCm38) |
splice site |
probably benign |
|
|
R0326:Chd1
|
UTSW |
17 |
15,768,568 (GRCm38) |
missense |
probably benign |
|
|
R0326:Chd1
|
UTSW |
17 |
15,768,566 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0372:Chd1
|
UTSW |
17 |
17,387,290 (GRCm38) |
missense |
probably benign |
0.14 |
|
R0391:Chd1
|
UTSW |
17 |
15,749,894 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0486:Chd1
|
UTSW |
17 |
15,734,342 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0637:Chd1
|
UTSW |
17 |
15,742,288 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R0675:Chd1
|
UTSW |
17 |
15,758,261 (GRCm38) |
unclassified |
probably benign |
|
|
R0701:Chd1
|
UTSW |
17 |
15,725,431 (GRCm38) |
missense |
probably benign |
|
|
R0788:Chd1
|
UTSW |
17 |
15,707,114 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R0848:Chd1
|
UTSW |
17 |
15,770,241 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0883:Chd1
|
UTSW |
17 |
15,725,431 (GRCm38) |
missense |
probably benign |
|
|
R1169:Chd1
|
UTSW |
17 |
15,735,732 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1218:Chd1
|
UTSW |
17 |
15,725,312 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1370:Chd1
|
UTSW |
17 |
17,387,480 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1470:Chd1
|
UTSW |
17 |
15,726,283 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R1470:Chd1
|
UTSW |
17 |
15,726,283 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R1478:Chd1
|
UTSW |
17 |
15,739,507 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1752:Chd1
|
UTSW |
17 |
15,743,232 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1759:Chd1
|
UTSW |
17 |
17,387,271 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1767:Chd1
|
UTSW |
17 |
15,770,303 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1938:Chd1
|
UTSW |
17 |
15,762,486 (GRCm38) |
missense |
probably benign |
0.39 |
|
R2007:Chd1
|
UTSW |
17 |
15,731,006 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2069:Chd1
|
UTSW |
17 |
15,742,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3771:Chd1
|
UTSW |
17 |
17,374,651 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3773:Chd1
|
UTSW |
17 |
17,374,651 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3849:Chd1
|
UTSW |
17 |
15,731,871 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4241:Chd1
|
UTSW |
17 |
15,770,027 (GRCm38) |
nonsense |
probably null |
|
|
R4242:Chd1
|
UTSW |
17 |
15,770,027 (GRCm38) |
nonsense |
probably null |
|
|
R4354:Chd1
|
UTSW |
17 |
17,390,001 (GRCm38) |
missense |
probably benign |
0.23 |
|
R4468:Chd1
|
UTSW |
17 |
15,760,395 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4469:Chd1
|
UTSW |
17 |
15,760,395 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4731:Chd1
|
UTSW |
17 |
17,377,817 (GRCm38) |
missense |
probably benign |
0.36 |
|
R4824:Chd1
|
UTSW |
17 |
15,733,124 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4840:Chd1
|
UTSW |
17 |
15,768,754 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4840:Chd1
|
UTSW |
17 |
15,768,753 (GRCm38) |
nonsense |
probably null |
|
|
R4880:Chd1
|
UTSW |
17 |
17,374,654 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4960:Chd1
|
UTSW |
17 |
15,742,231 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5071:Chd1
|
UTSW |
17 |
15,762,405 (GRCm38) |
missense |
probably benign |
|
|
R5078:Chd1
|
UTSW |
17 |
15,726,354 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R5114:Chd1
|
UTSW |
17 |
15,728,198 (GRCm38) |
missense |
probably benign |
0.25 |
|
R5268:Chd1
|
UTSW |
17 |
15,735,743 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5304:Chd1
|
UTSW |
17 |
15,770,268 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R5304:Chd1
|
UTSW |
17 |
15,754,951 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5307:Chd1
|
UTSW |
17 |
15,732,570 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5458:Chd1
|
UTSW |
17 |
15,738,549 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5553:Chd1
|
UTSW |
17 |
17,385,613 (GRCm38) |
missense |
probably benign |
0.17 |
|
R5623:Chd1
|
UTSW |
17 |
15,754,932 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6022:Chd1
|
UTSW |
17 |
17,377,773 (GRCm38) |
missense |
probably benign |
0.39 |
|
R6137:Chd1
|
UTSW |
17 |
15,758,688 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6373:Chd1
|
UTSW |
17 |
15,738,636 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6458:Chd1
|
UTSW |
17 |
15,730,602 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6476:Chd1
|
UTSW |
17 |
17,380,988 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6508:Chd1
|
UTSW |
17 |
15,738,633 (GRCm38) |
missense |
probably benign |
0.31 |
|
R6553:Chd1
|
UTSW |
17 |
15,725,430 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6745:Chd1
|
UTSW |
17 |
17,387,167 (GRCm38) |
missense |
probably benign |
0.08 |
|
R7107:Chd1
|
UTSW |
17 |
15,761,366 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7230:Chd1
|
UTSW |
17 |
15,706,937 (GRCm38) |
splice site |
probably null |
|
|
R7317:Chd1
|
UTSW |
17 |
15,742,274 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R7341:Chd1
|
UTSW |
17 |
15,770,237 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7421:Chd1
|
UTSW |
17 |
15,749,398 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7704:Chd1
|
UTSW |
17 |
15,767,475 (GRCm38) |
missense |
probably benign |
|
|
R7763:Chd1
|
UTSW |
17 |
15,733,041 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8156:Chd1
|
UTSW |
17 |
15,761,404 (GRCm38) |
missense |
probably benign |
|
|
R8194:Chd1
|
UTSW |
17 |
17,374,475 (GRCm38) |
start gained |
probably benign |
|
|
R8261:Chd1
|
UTSW |
17 |
17,387,542 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8338:Chd1
|
UTSW |
17 |
15,769,980 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8401:Chd1
|
UTSW |
17 |
15,743,211 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8411:Chd1
|
UTSW |
17 |
15,762,449 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9067:Chd1
|
UTSW |
17 |
15,730,845 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R9184:Chd1
|
UTSW |
17 |
15,742,289 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R9210:Chd1
|
UTSW |
17 |
15,730,505 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R9212:Chd1
|
UTSW |
17 |
15,730,505 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R9666:Chd1
|
UTSW |
17 |
15,735,714 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9673:Chd1
|
UTSW |
17 |
15,768,761 (GRCm38) |
missense |
probably benign |
0.24 |
|
Z1176:Chd1
|
UTSW |
17 |
15,768,733 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Chd1
|
UTSW |
17 |
15,766,347 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Z1177:Chd1
|
UTSW |
17 |
15,747,801 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTCCTCTTGGACTGCTCAGG -3'
(R):5'- AGAAAACTGTTGCTTTGAGCCATAC -3'
Sequencing Primer
(F):5'- GCTTTCCCCATGTGAAGCCAAAG -3'
(R):5'- GCTTTGAGCCATACTGGAAAATAG -3'
|
| Posted On |
2018-06-04 |
Incidental Mutation