Incidental Mutation 'R6502:Ccdc141'
| ID |
519769 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ccdc141
|
| Ensembl Gene |
ENSMUSG00000044033 |
| Gene Name |
coiled-coil domain containing 141 |
| Synonyms |
ENSMUSG00000075261, CAMDI, 2610301F02Rik |
| MMRRC Submission |
044634-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6502 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
76840246-77000980 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 77000745 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 29
(V29A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000052945
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000049544]
[ENSMUST00000111833]
[ENSMUST00000133503]
[ENSMUST00000164114]
|
| AlphaFold |
E9Q8Q6 |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000028406
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000049544
AA Change: V29A
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000052945
Gene: ENSMUSG00000044033
AA Change: V29A
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
26 |
128 |
2.87e-1 |
SMART |
|
Blast:SPEC
|
132 |
222 |
1e-40 |
BLAST |
|
low complexity region
|
223 |
251 |
N/A |
INTRINSIC |
|
SPEC
|
252 |
353 |
3.61e-1 |
SMART |
|
Blast:SPEC
|
356 |
453 |
2e-49 |
BLAST |
|
Blast:SPEC
|
461 |
562 |
1e-16 |
BLAST |
|
low complexity region
|
569 |
583 |
N/A |
INTRINSIC |
|
Blast:SPEC
|
688 |
772 |
7e-30 |
BLAST |
|
low complexity region
|
773 |
785 |
N/A |
INTRINSIC |
|
Blast:SPEC
|
790 |
894 |
2e-24 |
BLAST |
|
Blast:SPEC
|
907 |
1009 |
4e-44 |
BLAST |
|
Blast:SPEC
|
1012 |
1118 |
9e-63 |
BLAST |
|
low complexity region
|
1203 |
1231 |
N/A |
INTRINSIC |
|
Blast:IG
|
1305 |
1416 |
5e-54 |
BLAST |
|
SCOP:d1g1ca_
|
1406 |
1443 |
1e-9 |
SMART |
|
Blast:IG
|
1416 |
1444 |
2e-9 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000111833
AA Change: V29A
PolyPhen 2
Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000107464
Gene: ENSMUSG00000044033
AA Change: V29A
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:SPEC
|
26 |
60 |
4e-16 |
BLAST |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000131660
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000133503
AA Change: V29A
PolyPhen 2
Score 0.961 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000120312
Gene: ENSMUSG00000044033
AA Change: V29A
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:SPEC
|
26 |
60 |
4e-17 |
BLAST |
|
low complexity region
|
61 |
76 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000164114
AA Change: V29A
PolyPhen 2
Score 0.976 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000128736
Gene: ENSMUSG00000044033
AA Change: V29A
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
26 |
128 |
2.87e-1 |
SMART |
|
Blast:SPEC
|
132 |
222 |
2e-40 |
BLAST |
|
low complexity region
|
223 |
251 |
N/A |
INTRINSIC |
|
SPEC
|
252 |
353 |
3.61e-1 |
SMART |
|
Blast:SPEC
|
356 |
453 |
2e-49 |
BLAST |
|
Blast:SPEC
|
461 |
562 |
1e-16 |
BLAST |
|
low complexity region
|
569 |
583 |
N/A |
INTRINSIC |
|
Blast:SPEC
|
688 |
772 |
7e-30 |
BLAST |
|
low complexity region
|
773 |
785 |
N/A |
INTRINSIC |
|
Blast:SPEC
|
790 |
894 |
3e-24 |
BLAST |
|
Blast:SPEC
|
907 |
1009 |
4e-44 |
BLAST |
|
Blast:SPEC
|
1012 |
1118 |
1e-62 |
BLAST |
|
low complexity region
|
1203 |
1231 |
N/A |
INTRINSIC |
|
IGc2
|
1422 |
1489 |
1.27e-5 |
SMART |
|
transmembrane domain
|
1510 |
1529 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.2%
- 20x: 94.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous knockout impairs migration of neurons in the somatosensory cortex, resulting in increased anxiety and hyperactivity. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700013D24Rik |
A |
T |
6: 124,333,908 (GRCm39) |
I24K |
probably benign |
Het |
| Adamts9 |
A |
T |
6: 92,849,316 (GRCm39) |
C467S |
probably damaging |
Het |
| Adcy7 |
G |
A |
8: 89,052,107 (GRCm39) |
R925Q |
probably damaging |
Het |
| Akap6 |
G |
A |
12: 53,186,998 (GRCm39) |
G1471S |
probably damaging |
Het |
| Ap2b1 |
T |
C |
11: 83,233,505 (GRCm39) |
V506A |
probably damaging |
Het |
| Apob |
A |
G |
12: 8,051,814 (GRCm39) |
I1113M |
probably damaging |
Het |
| Arsg |
A |
T |
11: 109,408,162 (GRCm39) |
N105Y |
probably damaging |
Het |
| Blm |
T |
A |
7: 80,131,223 (GRCm39) |
Y872F |
probably damaging |
Het |
| Btaf1 |
A |
T |
19: 36,961,017 (GRCm39) |
N797Y |
probably benign |
Het |
| Camsap1 |
T |
C |
2: 25,846,320 (GRCm39) |
E201G |
probably damaging |
Het |
| Ccdc122 |
T |
A |
14: 77,279,509 (GRCm39) |
|
probably null |
Homo |
| Cd244a |
T |
A |
1: 171,405,447 (GRCm39) |
D277E |
probably benign |
Het |
| Cfap157 |
T |
C |
2: 32,670,690 (GRCm39) |
Y186C |
probably damaging |
Het |
| Ciita |
C |
T |
16: 10,329,774 (GRCm39) |
A686V |
probably damaging |
Het |
| Clptm1l |
T |
C |
13: 73,765,884 (GRCm39) |
|
probably null |
Het |
| Col16a1 |
C |
T |
4: 129,949,787 (GRCm39) |
P50L |
probably damaging |
Het |
| Crisp3 |
A |
T |
17: 40,546,804 (GRCm39) |
V38D |
probably damaging |
Het |
| Cyfip2 |
T |
C |
11: 46,112,173 (GRCm39) |
E1010G |
probably damaging |
Het |
| Dvl3 |
G |
A |
16: 20,346,133 (GRCm39) |
E488K |
probably damaging |
Het |
| Eed |
C |
A |
7: 89,626,237 (GRCm39) |
E45D |
probably benign |
Het |
| Eln |
A |
G |
5: 134,754,628 (GRCm39) |
|
probably benign |
Het |
| Fah |
T |
A |
7: 84,244,043 (GRCm39) |
I239F |
probably damaging |
Het |
| Fbxw5 |
T |
A |
2: 25,392,448 (GRCm39) |
Y77N |
possibly damaging |
Het |
| Garnl3 |
T |
C |
2: 32,896,833 (GRCm39) |
E602G |
possibly damaging |
Het |
| Gkn3 |
A |
T |
6: 87,365,786 (GRCm39) |
M11K |
probably benign |
Het |
| Glt1d1 |
A |
G |
5: 127,784,045 (GRCm39) |
Y333C |
probably damaging |
Het |
| Gm10762 |
A |
T |
2: 128,809,090 (GRCm39) |
Y86* |
probably null |
Het |
| Gm14496 |
A |
G |
2: 181,642,386 (GRCm39) |
M686V |
probably benign |
Het |
| Gse1 |
T |
A |
8: 121,280,428 (GRCm39) |
|
probably null |
Het |
| Herc4 |
C |
A |
10: 63,153,197 (GRCm39) |
T1035K |
probably benign |
Het |
| Hmcn2 |
T |
A |
2: 31,272,490 (GRCm39) |
N1323K |
probably damaging |
Het |
| Hnrnpd |
T |
A |
5: 100,114,025 (GRCm39) |
E3D |
probably damaging |
Het |
| Htr7 |
T |
A |
19: 35,947,010 (GRCm39) |
I335F |
probably damaging |
Het |
| Ift70b |
T |
A |
2: 75,767,448 (GRCm39) |
N435I |
possibly damaging |
Het |
| Itgae |
A |
T |
11: 73,036,418 (GRCm39) |
I1119F |
probably benign |
Het |
| Lcn11 |
T |
C |
2: 25,669,103 (GRCm39) |
F137S |
probably benign |
Het |
| Lrp3 |
T |
G |
7: 34,903,413 (GRCm39) |
D311A |
possibly damaging |
Het |
| Lrrc1 |
G |
T |
9: 77,349,473 (GRCm39) |
D364E |
probably damaging |
Het |
| Lrrc37a |
T |
A |
11: 103,383,005 (GRCm39) |
E2456V |
unknown |
Het |
| Lrriq1 |
T |
C |
10: 103,063,045 (GRCm39) |
Y87C |
probably damaging |
Het |
| Mcc |
A |
T |
18: 44,601,457 (GRCm39) |
L449* |
probably null |
Het |
| Mcc |
A |
T |
18: 44,601,458 (GRCm39) |
L624M |
probably damaging |
Het |
| Mcm9 |
T |
C |
10: 53,488,935 (GRCm39) |
T496A |
probably damaging |
Het |
| Myef2 |
T |
A |
2: 124,958,602 (GRCm39) |
D109V |
probably damaging |
Het |
| Myom3 |
C |
T |
4: 135,489,824 (GRCm39) |
|
probably benign |
Het |
| Nanos1 |
G |
T |
19: 60,744,977 (GRCm39) |
G92W |
possibly damaging |
Het |
| Ncor1 |
T |
A |
11: 62,272,240 (GRCm39) |
K84* |
probably null |
Het |
| Neb |
T |
A |
2: 52,181,094 (GRCm39) |
D1171V |
probably benign |
Het |
| Notch3 |
A |
G |
17: 32,377,191 (GRCm39) |
W267R |
probably damaging |
Het |
| Or5d39 |
A |
T |
2: 87,980,360 (GRCm39) |
M1K |
probably null |
Het |
| Or8d1 |
A |
C |
9: 38,766,933 (GRCm39) |
T192P |
probably damaging |
Het |
| Per2 |
A |
G |
1: 91,355,485 (GRCm39) |
S758P |
probably benign |
Het |
| Pi4k2a |
A |
G |
19: 42,079,371 (GRCm39) |
Q144R |
probably benign |
Het |
| Pirb |
A |
T |
7: 3,720,392 (GRCm39) |
V327E |
probably benign |
Het |
| Pla2g4a |
C |
T |
1: 149,748,367 (GRCm39) |
W272* |
probably null |
Het |
| Plekha4 |
T |
A |
7: 45,180,000 (GRCm39) |
M1K |
probably null |
Het |
| Ppt2 |
A |
G |
17: 34,844,894 (GRCm39) |
C117R |
probably damaging |
Het |
| Prph |
A |
T |
15: 98,954,267 (GRCm39) |
I222F |
probably damaging |
Het |
| Rbm43 |
T |
C |
2: 51,815,588 (GRCm39) |
D211G |
probably damaging |
Het |
| Rims2 |
A |
G |
15: 39,398,251 (GRCm39) |
D1072G |
probably benign |
Het |
| Rnf123 |
G |
T |
9: 107,945,531 (GRCm39) |
Q380K |
possibly damaging |
Het |
| Rnf145 |
T |
C |
11: 44,415,932 (GRCm39) |
F49S |
probably damaging |
Het |
| Sall4 |
A |
G |
2: 168,597,628 (GRCm39) |
I404T |
probably damaging |
Het |
| Slc25a39 |
G |
A |
11: 102,295,286 (GRCm39) |
P228L |
probably damaging |
Het |
| Tbc1d14 |
T |
C |
5: 36,677,825 (GRCm39) |
T377A |
possibly damaging |
Het |
| Tbc1d17 |
A |
G |
7: 44,491,049 (GRCm39) |
I555T |
probably benign |
Het |
| Tmem131l |
A |
T |
3: 83,829,715 (GRCm39) |
S980T |
probably damaging |
Het |
| Tmem14a |
G |
T |
1: 21,299,662 (GRCm39) |
L97F |
possibly damaging |
Het |
| Tmem98 |
T |
C |
11: 80,703,461 (GRCm39) |
V26A |
probably benign |
Het |
| Tmppe |
G |
T |
9: 114,234,720 (GRCm39) |
G340W |
probably damaging |
Het |
| Tsc1 |
T |
C |
2: 28,555,613 (GRCm39) |
S237P |
probably damaging |
Het |
| Ubr4 |
C |
T |
4: 139,171,982 (GRCm39) |
R2992W |
probably damaging |
Het |
| Ugt2a2 |
A |
G |
5: 87,608,318 (GRCm39) |
V673A |
possibly damaging |
Het |
| Vmn2r19 |
T |
C |
6: 123,293,067 (GRCm39) |
Y370H |
possibly damaging |
Het |
| Vmn2r20 |
A |
G |
6: 123,373,342 (GRCm39) |
F500S |
possibly damaging |
Het |
| Zc3h7b |
A |
G |
15: 81,653,252 (GRCm39) |
Y47C |
probably benign |
Het |
| Zdhhc13 |
A |
G |
7: 48,465,308 (GRCm39) |
E406G |
possibly damaging |
Het |
| Zfp418 |
T |
C |
7: 7,185,599 (GRCm39) |
S521P |
possibly damaging |
Het |
|
| Other mutations in Ccdc141 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00517:Ccdc141
|
APN |
2 |
76,884,988 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01396:Ccdc141
|
APN |
2 |
76,958,669 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01408:Ccdc141
|
APN |
2 |
76,876,023 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01633:Ccdc141
|
APN |
2 |
76,919,593 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01982:Ccdc141
|
APN |
2 |
76,861,003 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02105:Ccdc141
|
APN |
2 |
76,879,921 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02307:Ccdc141
|
APN |
2 |
76,859,686 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02645:Ccdc141
|
APN |
2 |
76,905,211 (GRCm39) |
nonsense |
probably null |
|
|
IGL02737:Ccdc141
|
APN |
2 |
76,888,268 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02740:Ccdc141
|
APN |
2 |
76,884,953 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02949:Ccdc141
|
APN |
2 |
76,857,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03127:Ccdc141
|
APN |
2 |
76,859,579 (GRCm39) |
critical splice donor site |
probably null |
|
|
Verloren
|
UTSW |
2 |
76,857,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Verschied
|
UTSW |
2 |
76,938,700 (GRCm39) |
splice site |
probably benign |
|
|
R0153:Ccdc141
|
UTSW |
2 |
76,995,582 (GRCm39) |
intron |
probably benign |
|
|
R0384:Ccdc141
|
UTSW |
2 |
76,857,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0423:Ccdc141
|
UTSW |
2 |
76,869,794 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0573:Ccdc141
|
UTSW |
2 |
76,869,837 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1332:Ccdc141
|
UTSW |
2 |
76,844,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1336:Ccdc141
|
UTSW |
2 |
76,844,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1355:Ccdc141
|
UTSW |
2 |
76,860,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1416:Ccdc141
|
UTSW |
2 |
76,845,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1659:Ccdc141
|
UTSW |
2 |
76,885,027 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1726:Ccdc141
|
UTSW |
2 |
76,938,700 (GRCm39) |
splice site |
probably benign |
|
|
R1799:Ccdc141
|
UTSW |
2 |
76,842,015 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1837:Ccdc141
|
UTSW |
2 |
76,842,009 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1839:Ccdc141
|
UTSW |
2 |
76,842,009 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1918:Ccdc141
|
UTSW |
2 |
76,845,047 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2019:Ccdc141
|
UTSW |
2 |
76,841,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2133:Ccdc141
|
UTSW |
2 |
76,889,951 (GRCm39) |
missense |
probably benign |
0.28 |
|
R2158:Ccdc141
|
UTSW |
2 |
76,861,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2256:Ccdc141
|
UTSW |
2 |
76,962,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2359:Ccdc141
|
UTSW |
2 |
77,000,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2382:Ccdc141
|
UTSW |
2 |
76,905,342 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2382:Ccdc141
|
UTSW |
2 |
76,841,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3110:Ccdc141
|
UTSW |
2 |
76,869,830 (GRCm39) |
missense |
probably benign |
0.31 |
|
R3112:Ccdc141
|
UTSW |
2 |
76,869,830 (GRCm39) |
missense |
probably benign |
0.31 |
|
R4334:Ccdc141
|
UTSW |
2 |
77,000,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4493:Ccdc141
|
UTSW |
2 |
76,962,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4494:Ccdc141
|
UTSW |
2 |
76,962,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4628:Ccdc141
|
UTSW |
2 |
76,890,024 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4748:Ccdc141
|
UTSW |
2 |
76,888,324 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4810:Ccdc141
|
UTSW |
2 |
76,876,099 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4824:Ccdc141
|
UTSW |
2 |
76,954,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4829:Ccdc141
|
UTSW |
2 |
76,905,260 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4920:Ccdc141
|
UTSW |
2 |
76,998,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5024:Ccdc141
|
UTSW |
2 |
76,885,047 (GRCm39) |
missense |
probably benign |
0.17 |
|
R5073:Ccdc141
|
UTSW |
2 |
76,954,722 (GRCm39) |
splice site |
probably null |
|
|
R5251:Ccdc141
|
UTSW |
2 |
76,858,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5252:Ccdc141
|
UTSW |
2 |
76,962,593 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5534:Ccdc141
|
UTSW |
2 |
76,888,241 (GRCm39) |
missense |
probably benign |
|
|
R5539:Ccdc141
|
UTSW |
2 |
76,845,437 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5551:Ccdc141
|
UTSW |
2 |
76,844,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5784:Ccdc141
|
UTSW |
2 |
76,859,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5837:Ccdc141
|
UTSW |
2 |
76,938,781 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R5850:Ccdc141
|
UTSW |
2 |
76,859,747 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6050:Ccdc141
|
UTSW |
2 |
76,842,075 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6263:Ccdc141
|
UTSW |
2 |
76,938,807 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6580:Ccdc141
|
UTSW |
2 |
76,842,099 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6865:Ccdc141
|
UTSW |
2 |
76,859,579 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7014:Ccdc141
|
UTSW |
2 |
76,962,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7094:Ccdc141
|
UTSW |
2 |
76,871,797 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7195:Ccdc141
|
UTSW |
2 |
76,879,927 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7300:Ccdc141
|
UTSW |
2 |
76,845,038 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7654:Ccdc141
|
UTSW |
2 |
76,872,822 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7834:Ccdc141
|
UTSW |
2 |
76,889,889 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7868:Ccdc141
|
UTSW |
2 |
76,938,756 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7986:Ccdc141
|
UTSW |
2 |
76,845,461 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8059:Ccdc141
|
UTSW |
2 |
76,875,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8082:Ccdc141
|
UTSW |
2 |
76,954,588 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8439:Ccdc141
|
UTSW |
2 |
76,889,894 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8508:Ccdc141
|
UTSW |
2 |
76,962,588 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8695:Ccdc141
|
UTSW |
2 |
76,879,963 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8880:Ccdc141
|
UTSW |
2 |
76,845,556 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8992:Ccdc141
|
UTSW |
2 |
76,844,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9048:Ccdc141
|
UTSW |
2 |
76,853,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9260:Ccdc141
|
UTSW |
2 |
76,844,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9297:Ccdc141
|
UTSW |
2 |
76,842,028 (GRCm39) |
missense |
probably benign |
0.34 |
|
R9418:Ccdc141
|
UTSW |
2 |
76,871,766 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9601:Ccdc141
|
UTSW |
2 |
76,885,073 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R9628:Ccdc141
|
UTSW |
2 |
76,844,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9763:Ccdc141
|
UTSW |
2 |
76,869,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Ccdc141
|
UTSW |
2 |
76,958,616 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1177:Ccdc141
|
UTSW |
2 |
76,845,493 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTTACCCTGAAAAGCAGCTGC -3'
(R):5'- ATCAGTGTGAACAGAGGCGC -3'
Sequencing Primer
(F):5'- AAGCAGCTGCCAACTTGTTG -3'
(R):5'- TTCCCTGAAAGAGTCCCGGTAG -3'
|
| Posted On |
2018-06-06 |
Incidental Mutation