Incidental Mutation 'R6502:Rnf123'
| ID |
519802 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rnf123
|
| Ensembl Gene |
ENSMUSG00000041528 |
| Gene Name |
ring finger protein 123 |
| Synonyms |
KPC1 |
| MMRRC Submission |
044634-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.174)
|
| Stock # |
R6502 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
108051534-108083346 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 108068332 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Lysine
at position 380
(Q380K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136953
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047746]
[ENSMUST00000160249]
[ENSMUST00000160649]
[ENSMUST00000161828]
[ENSMUST00000162355]
[ENSMUST00000162516]
[ENSMUST00000174504]
[ENSMUST00000178267]
|
| AlphaFold |
Q5XPI3 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000047746
AA Change: Q380K
PolyPhen 2
Score 0.462 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000040803
Gene: ENSMUSG00000041528
AA Change: Q380K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1047 |
1067 |
N/A |
INTRINSIC |
|
low complexity region
|
1242 |
1251 |
N/A |
INTRINSIC |
|
RING
|
1260 |
1297 |
5.27e-4 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159136
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000160249
AA Change: Q380K
PolyPhen 2
Score 0.462 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000124548
Gene: ENSMUSG00000041528
AA Change: Q380K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1245 |
N/A |
INTRINSIC |
|
RING
|
1254 |
1291 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160649
AA Change: Q380K
PolyPhen 2
Score 0.121 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000125495
Gene: ENSMUSG00000041528
AA Change: Q380K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000161673
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161828
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000162152
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000162355
AA Change: Q380K
PolyPhen 2
Score 0.462 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000125745
Gene: ENSMUSG00000041528
AA Change: Q380K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1047 |
1067 |
N/A |
INTRINSIC |
|
low complexity region
|
1242 |
1251 |
N/A |
INTRINSIC |
|
RING
|
1260 |
1297 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162516
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174504
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000178267
AA Change: Q380K
PolyPhen 2
Score 0.462 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000136953
Gene: ENSMUSG00000041528
AA Change: Q380K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1245 |
N/A |
INTRINSIC |
|
RING
|
1254 |
1291 |
5.27e-4 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.2%
- 20x: 94.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700013D24Rik |
A |
T |
6: 124,356,949 (GRCm38) |
I24K |
probably benign |
Het |
| Adamts9 |
A |
T |
6: 92,872,335 (GRCm38) |
C467S |
probably damaging |
Het |
| Adcy7 |
G |
A |
8: 88,325,479 (GRCm38) |
R925Q |
probably damaging |
Het |
| Akap6 |
G |
A |
12: 53,140,215 (GRCm38) |
G1471S |
probably damaging |
Het |
| Ap2b1 |
T |
C |
11: 83,342,679 (GRCm38) |
V506A |
probably damaging |
Het |
| Apob |
A |
G |
12: 8,001,814 (GRCm38) |
I1113M |
probably damaging |
Het |
| Arsg |
A |
T |
11: 109,517,336 (GRCm38) |
N105Y |
probably damaging |
Het |
| Blm |
T |
A |
7: 80,481,475 (GRCm38) |
Y872F |
probably damaging |
Het |
| Btaf1 |
A |
T |
19: 36,983,617 (GRCm38) |
N797Y |
probably benign |
Het |
| Camsap1 |
T |
C |
2: 25,956,308 (GRCm38) |
E201G |
probably damaging |
Het |
| Ccdc122 |
T |
A |
14: 77,042,069 (GRCm38) |
|
probably null |
Homo |
| Ccdc141 |
A |
G |
2: 77,170,401 (GRCm38) |
V29A |
probably damaging |
Het |
| Cd244 |
T |
A |
1: 171,577,879 (GRCm38) |
D277E |
probably benign |
Het |
| Cfap157 |
T |
C |
2: 32,780,678 (GRCm38) |
Y186C |
probably damaging |
Het |
| Ciita |
C |
T |
16: 10,511,910 (GRCm38) |
A686V |
probably damaging |
Het |
| Clptm1l |
T |
C |
13: 73,617,765 (GRCm38) |
|
probably null |
Het |
| Col16a1 |
C |
T |
4: 130,055,994 (GRCm38) |
P50L |
probably damaging |
Het |
| Crisp3 |
A |
T |
17: 40,235,913 (GRCm38) |
V38D |
probably damaging |
Het |
| Cyfip2 |
T |
C |
11: 46,221,346 (GRCm38) |
E1010G |
probably damaging |
Het |
| Dvl3 |
G |
A |
16: 20,527,383 (GRCm38) |
E488K |
probably damaging |
Het |
| Eed |
C |
A |
7: 89,977,029 (GRCm38) |
E45D |
probably benign |
Het |
| Eln |
A |
G |
5: 134,725,774 (GRCm38) |
|
probably benign |
Het |
| Fah |
T |
A |
7: 84,594,835 (GRCm38) |
I239F |
probably damaging |
Het |
| Fbxw5 |
T |
A |
2: 25,502,436 (GRCm38) |
Y77N |
possibly damaging |
Het |
| Garnl3 |
T |
C |
2: 33,006,821 (GRCm38) |
E602G |
possibly damaging |
Het |
| Gkn3 |
A |
T |
6: 87,388,804 (GRCm38) |
M11K |
probably benign |
Het |
| Glt1d1 |
A |
G |
5: 127,706,981 (GRCm38) |
Y333C |
probably damaging |
Het |
| Gm10762 |
A |
T |
2: 128,967,170 (GRCm38) |
Y86* |
probably null |
Het |
| Gm14496 |
A |
G |
2: 182,000,593 (GRCm38) |
M686V |
probably benign |
Het |
| Gse1 |
T |
A |
8: 120,553,689 (GRCm38) |
|
probably null |
Het |
| Herc4 |
C |
A |
10: 63,317,418 (GRCm38) |
T1035K |
probably benign |
Het |
| Hmcn2 |
T |
A |
2: 31,382,478 (GRCm38) |
N1323K |
probably damaging |
Het |
| Hnrnpd |
T |
A |
5: 99,966,166 (GRCm38) |
E3D |
probably damaging |
Het |
| Htr7 |
T |
A |
19: 35,969,610 (GRCm38) |
I335F |
probably damaging |
Het |
| Itgae |
A |
T |
11: 73,145,592 (GRCm38) |
I1119F |
probably benign |
Het |
| Lcn11 |
T |
C |
2: 25,779,091 (GRCm38) |
F137S |
probably benign |
Het |
| Lrp3 |
T |
G |
7: 35,203,988 (GRCm38) |
D311A |
possibly damaging |
Het |
| Lrrc1 |
G |
T |
9: 77,442,191 (GRCm38) |
D364E |
probably damaging |
Het |
| Lrrc37a |
T |
A |
11: 103,492,179 (GRCm38) |
E2456V |
unknown |
Het |
| Lrriq1 |
T |
C |
10: 103,227,184 (GRCm38) |
Y87C |
probably damaging |
Het |
| Mcc |
A |
T |
18: 44,468,390 (GRCm38) |
L449* |
probably null |
Het |
| Mcc |
A |
T |
18: 44,468,391 (GRCm38) |
L624M |
probably damaging |
Het |
| Mcm9 |
T |
C |
10: 53,612,839 (GRCm38) |
T496A |
probably damaging |
Het |
| Myef2 |
T |
A |
2: 125,116,682 (GRCm38) |
D109V |
probably damaging |
Het |
| Myom3 |
C |
T |
4: 135,762,513 (GRCm38) |
|
probably benign |
Het |
| Nanos1 |
G |
T |
19: 60,756,539 (GRCm38) |
G92W |
possibly damaging |
Het |
| Ncor1 |
T |
A |
11: 62,381,414 (GRCm38) |
K84* |
probably null |
Het |
| Neb |
T |
A |
2: 52,291,082 (GRCm38) |
D1171V |
probably benign |
Het |
| Notch3 |
A |
G |
17: 32,158,217 (GRCm38) |
W267R |
probably damaging |
Het |
| Olfr1167 |
A |
T |
2: 88,150,016 (GRCm38) |
M1K |
probably null |
Het |
| Olfr26 |
A |
C |
9: 38,855,637 (GRCm38) |
T192P |
probably damaging |
Het |
| Per2 |
A |
G |
1: 91,427,763 (GRCm38) |
S758P |
probably benign |
Het |
| Pi4k2a |
A |
G |
19: 42,090,932 (GRCm38) |
Q144R |
probably benign |
Het |
| Pirb |
A |
T |
7: 3,717,393 (GRCm38) |
V327E |
probably benign |
Het |
| Pla2g4a |
C |
T |
1: 149,872,616 (GRCm38) |
W272* |
probably null |
Het |
| Plekha4 |
T |
A |
7: 45,530,576 (GRCm38) |
M1K |
probably null |
Het |
| Ppt2 |
A |
G |
17: 34,625,920 (GRCm38) |
C117R |
probably damaging |
Het |
| Prph |
A |
T |
15: 99,056,386 (GRCm38) |
I222F |
probably damaging |
Het |
| Rbm43 |
T |
C |
2: 51,925,576 (GRCm38) |
D211G |
probably damaging |
Het |
| Rims2 |
A |
G |
15: 39,534,855 (GRCm38) |
D1072G |
probably benign |
Het |
| Rnf145 |
T |
C |
11: 44,525,105 (GRCm38) |
F49S |
probably damaging |
Het |
| Sall4 |
A |
G |
2: 168,755,708 (GRCm38) |
I404T |
probably damaging |
Het |
| Slc25a39 |
G |
A |
11: 102,404,460 (GRCm38) |
P228L |
probably damaging |
Het |
| Tbc1d14 |
T |
C |
5: 36,520,481 (GRCm38) |
T377A |
possibly damaging |
Het |
| Tbc1d17 |
A |
G |
7: 44,841,625 (GRCm38) |
I555T |
probably benign |
Het |
| Tmem131l |
A |
T |
3: 83,922,408 (GRCm38) |
S980T |
probably damaging |
Het |
| Tmem14a |
G |
T |
1: 21,229,438 (GRCm38) |
L97F |
possibly damaging |
Het |
| Tmem98 |
T |
C |
11: 80,812,635 (GRCm38) |
V26A |
probably benign |
Het |
| Tmppe |
G |
T |
9: 114,405,652 (GRCm38) |
G340W |
probably damaging |
Het |
| Tsc1 |
T |
C |
2: 28,665,601 (GRCm38) |
S237P |
probably damaging |
Het |
| Ttc30b |
T |
A |
2: 75,937,104 (GRCm38) |
N435I |
possibly damaging |
Het |
| Ubr4 |
C |
T |
4: 139,444,671 (GRCm38) |
R2992W |
probably damaging |
Het |
| Ugt2a2 |
A |
G |
5: 87,460,459 (GRCm38) |
V673A |
possibly damaging |
Het |
| Vmn2r19 |
T |
C |
6: 123,316,108 (GRCm38) |
Y370H |
possibly damaging |
Het |
| Vmn2r20 |
A |
G |
6: 123,396,383 (GRCm38) |
F500S |
possibly damaging |
Het |
| Zc3h7b |
A |
G |
15: 81,769,051 (GRCm38) |
Y47C |
probably benign |
Het |
| Zdhhc13 |
A |
G |
7: 48,815,560 (GRCm38) |
E406G |
possibly damaging |
Het |
| Zfp418 |
T |
C |
7: 7,182,600 (GRCm38) |
S521P |
possibly damaging |
Het |
|
| Other mutations in Rnf123 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00950:Rnf123
|
APN |
9 |
108,067,395 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01358:Rnf123
|
APN |
9 |
108,069,182 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01464:Rnf123
|
APN |
9 |
108,052,302 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01637:Rnf123
|
APN |
9 |
108,058,238 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01669:Rnf123
|
APN |
9 |
108,058,356 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01905:Rnf123
|
APN |
9 |
108,071,370 (GRCm38) |
splice site |
probably benign |
|
|
IGL02070:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02072:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02073:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02074:Rnf123
|
APN |
9 |
108,066,889 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02079:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02080:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02231:Rnf123
|
APN |
9 |
108,066,399 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL02281:Rnf123
|
APN |
9 |
108,071,452 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02336:Rnf123
|
APN |
9 |
108,061,842 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02543:Rnf123
|
APN |
9 |
108,066,348 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02565:Rnf123
|
APN |
9 |
108,052,212 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02571:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02572:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02574:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02586:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02589:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02600:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02601:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02602:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02603:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02609:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02628:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02629:Rnf123
|
APN |
9 |
108,070,789 (GRCm38) |
splice site |
probably benign |
|
|
IGL02629:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02630:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02631:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02632:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02650:Rnf123
|
APN |
9 |
108,069,748 (GRCm38) |
missense |
probably benign |
0.29 |
|
IGL02690:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02691:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02692:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02693:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02713:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02736:Rnf123
|
APN |
9 |
108,068,302 (GRCm38) |
nonsense |
probably null |
|
|
IGL02929:Rnf123
|
APN |
9 |
108,069,076 (GRCm38) |
missense |
probably benign |
|
|
R1175:Rnf123
|
UTSW |
9 |
108,077,373 (GRCm38) |
missense |
probably benign |
|
|
R1465:Rnf123
|
UTSW |
9 |
108,071,466 (GRCm38) |
splice site |
probably benign |
|
|
R1502:Rnf123
|
UTSW |
9 |
108,068,510 (GRCm38) |
splice site |
probably null |
|
|
R1682:Rnf123
|
UTSW |
9 |
108,077,398 (GRCm38) |
missense |
probably benign |
0.16 |
|
R1817:Rnf123
|
UTSW |
9 |
108,062,926 (GRCm38) |
missense |
probably benign |
0.41 |
|
R1855:Rnf123
|
UTSW |
9 |
108,061,791 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2394:Rnf123
|
UTSW |
9 |
108,063,536 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2483:Rnf123
|
UTSW |
9 |
108,063,521 (GRCm38) |
missense |
probably benign |
0.16 |
|
R3896:Rnf123
|
UTSW |
9 |
108,069,103 (GRCm38) |
splice site |
probably benign |
|
|
R3940:Rnf123
|
UTSW |
9 |
108,064,035 (GRCm38) |
splice site |
probably benign |
|
|
R4206:Rnf123
|
UTSW |
9 |
108,063,963 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4641:Rnf123
|
UTSW |
9 |
108,058,587 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4714:Rnf123
|
UTSW |
9 |
108,052,439 (GRCm38) |
splice site |
probably null |
|
|
R4767:Rnf123
|
UTSW |
9 |
108,052,089 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4849:Rnf123
|
UTSW |
9 |
108,056,091 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4899:Rnf123
|
UTSW |
9 |
108,063,680 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5274:Rnf123
|
UTSW |
9 |
108,064,003 (GRCm38) |
frame shift |
probably null |
|
|
R5275:Rnf123
|
UTSW |
9 |
108,064,003 (GRCm38) |
frame shift |
probably null |
|
|
R5276:Rnf123
|
UTSW |
9 |
108,064,003 (GRCm38) |
frame shift |
probably null |
|
|
R5294:Rnf123
|
UTSW |
9 |
108,064,003 (GRCm38) |
frame shift |
probably null |
|
|
R5295:Rnf123
|
UTSW |
9 |
108,064,003 (GRCm38) |
frame shift |
probably null |
|
|
R5394:Rnf123
|
UTSW |
9 |
108,070,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5717:Rnf123
|
UTSW |
9 |
108,067,424 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6186:Rnf123
|
UTSW |
9 |
108,069,958 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R6449:Rnf123
|
UTSW |
9 |
108,056,053 (GRCm38) |
missense |
probably benign |
0.17 |
|
R6944:Rnf123
|
UTSW |
9 |
108,063,623 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7003:Rnf123
|
UTSW |
9 |
108,063,683 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7088:Rnf123
|
UTSW |
9 |
108,058,536 (GRCm38) |
missense |
probably null |
1.00 |
|
R7092:Rnf123
|
UTSW |
9 |
108,068,600 (GRCm38) |
missense |
probably benign |
0.07 |
|
R7100:Rnf123
|
UTSW |
9 |
108,056,639 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7257:Rnf123
|
UTSW |
9 |
108,069,029 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7453:Rnf123
|
UTSW |
9 |
108,070,408 (GRCm38) |
splice site |
probably null |
|
|
R7468:Rnf123
|
UTSW |
9 |
108,069,009 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7517:Rnf123
|
UTSW |
9 |
108,070,274 (GRCm38) |
nonsense |
probably null |
|
|
R7577:Rnf123
|
UTSW |
9 |
108,070,619 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8296:Rnf123
|
UTSW |
9 |
108,062,890 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8322:Rnf123
|
UTSW |
9 |
108,068,507 (GRCm38) |
missense |
probably benign |
0.26 |
|
R8754:Rnf123
|
UTSW |
9 |
108,071,164 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8783:Rnf123
|
UTSW |
9 |
108,069,073 (GRCm38) |
missense |
probably benign |
|
|
R9052:Rnf123
|
UTSW |
9 |
108,059,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9156:Rnf123
|
UTSW |
9 |
108,063,028 (GRCm38) |
splice site |
probably benign |
|
|
R9170:Rnf123
|
UTSW |
9 |
108,071,176 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9332:Rnf123
|
UTSW |
9 |
108,067,505 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9385:Rnf123
|
UTSW |
9 |
108,052,268 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9394:Rnf123
|
UTSW |
9 |
108,065,706 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9432:Rnf123
|
UTSW |
9 |
108,059,809 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9717:Rnf123
|
UTSW |
9 |
108,077,764 (GRCm38) |
missense |
probably benign |
0.43 |
|
Z1176:Rnf123
|
UTSW |
9 |
108,062,981 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Rnf123
|
UTSW |
9 |
108,058,395 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAGGTATTACATGGCAGATCTGTC -3'
(R):5'- AGATCTTGGACCTCTTGTGGC -3'
Sequencing Primer
(F):5'- CATTGCTAAGCAGGAACTTGC -3'
(R):5'- CTCTTCATGGAGGTAAGATTTCTGAC -3'
|
| Posted On |
2018-06-06 |
Incidental Mutation