Incidental Mutation 'IGL01096:Vmn2r83'
ID52088
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r83
Ensembl Gene ENSMUSG00000091381
Gene Namevomeronasal 2, receptor 83
SynonymsEG625029
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.098) question?
Stock #IGL01096
Quality Score
Status
Chromosome10
Chromosomal Location79468943-79492154 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 79477828 bp
ZygosityHeterozygous
Amino Acid Change Glutamic Acid to Glycine at position 90 (E90G)
Ref Sequence ENSEMBL: ENSMUSP00000131426 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000167976]
Predicted Effect probably damaging
Transcript: ENSMUST00000167976
AA Change: E90G

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000131426
Gene: ENSMUSG00000091381
AA Change: E90G

DomainStartEndE-ValueType
signal peptide 1 20 N/A INTRINSIC
Pfam:ANF_receptor 79 473 1.5e-33 PFAM
Pfam:NCD3G 516 569 6.2e-22 PFAM
Pfam:7tm_3 602 837 8.1e-52 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrg3 A T 8: 95,039,593 M351L possibly damaging Het
Alk T C 17: 71,921,896 K725E possibly damaging Het
Dspp T A 5: 104,175,367 H125Q possibly damaging Het
Elmo2 A T 2: 165,296,987 probably benign Het
Erg A G 16: 95,390,053 probably benign Het
Fam20c A G 5: 138,809,155 E513G possibly damaging Het
Gatsl3 A C 11: 4,221,850 E309A probably damaging Het
Gm9839 G T 1: 32,520,836 T55N possibly damaging Het
Gpd2 A T 2: 57,338,867 M228L probably damaging Het
Hp A T 8: 109,575,401 M305K probably benign Het
Ifng T A 10: 118,445,269 probably benign Het
Igkv9-123 T C 6: 67,954,465 D39G possibly damaging Het
Melk T A 4: 44,347,262 F431I probably benign Het
Olfr1180 A G 2: 88,411,791 M289T probably damaging Het
Olfr1335 A G 4: 118,809,456 V136A probably damaging Het
Olfr536 A T 7: 140,504,184 S92T probably damaging Het
Olfr639 A C 7: 104,012,114 L196W probably damaging Het
Olfr944 G A 9: 39,218,116 G253D probably damaging Het
Pappa T C 4: 65,189,316 Y655H probably damaging Het
Prss58 A T 6: 40,895,465 I208N probably damaging Het
Ryr2 T A 13: 11,703,544 I2720F probably damaging Het
Slc13a1 G T 6: 24,104,077 T322K probably damaging Het
Spag17 T C 3: 100,063,375 F1292L probably benign Het
Tbx5 A G 5: 119,883,026 T366A probably benign Het
Tmeff2 G A 1: 50,930,546 probably benign Het
Tmem101 C A 11: 102,154,552 probably null Het
Tpp2 C A 1: 43,960,888 P389T probably damaging Het
Tyk2 A G 9: 21,108,863 Y1000H probably damaging Het
Ush2a C A 1: 188,678,377 N2407K probably damaging Het
Vmn1r94 C T 7: 20,167,636 V248I probably damaging Het
Vmn2r12 T A 5: 109,086,259 I696F probably damaging Het
Washc5 T C 15: 59,350,211 probably benign Het
Wee2 A G 6: 40,463,253 E445G probably benign Het
Zfp518b T C 5: 38,672,788 T625A probably benign Het
Other mutations in Vmn2r83
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00226:Vmn2r83 APN 10 79478971 missense probably damaging 1.00
IGL01542:Vmn2r83 APN 10 79479012 missense probably benign 0.30
IGL01803:Vmn2r83 APN 10 79469060 missense probably benign 0.01
IGL02110:Vmn2r83 APN 10 79491700 missense possibly damaging 0.82
IGL02347:Vmn2r83 APN 10 79480233 missense possibly damaging 0.75
IGL02417:Vmn2r83 APN 10 79479047 missense probably benign 0.00
IGL02544:Vmn2r83 APN 10 79481459 splice site probably benign
IGL02683:Vmn2r83 APN 10 79491281 missense probably benign
IGL02976:Vmn2r83 APN 10 79468998 missense probably benign 0.00
PIT4378001:Vmn2r83 UTSW 10 79469015 missense probably benign 0.00
PIT4468001:Vmn2r83 UTSW 10 79478050 missense probably damaging 1.00
R0092:Vmn2r83 UTSW 10 79491964 missense probably damaging 1.00
R1391:Vmn2r83 UTSW 10 79479097 missense probably damaging 0.96
R1539:Vmn2r83 UTSW 10 79491925 missense probably damaging 1.00
R1575:Vmn2r83 UTSW 10 79479122 missense probably damaging 0.98
R2033:Vmn2r83 UTSW 10 79491819 missense probably benign 0.03
R3916:Vmn2r83 UTSW 10 79478910 missense probably benign 0.01
R3967:Vmn2r83 UTSW 10 79491320 missense probably benign 0.00
R4840:Vmn2r83 UTSW 10 79477848 missense possibly damaging 0.73
R5063:Vmn2r83 UTSW 10 79479087 missense probably benign 0.04
R5630:Vmn2r83 UTSW 10 79491951 missense possibly damaging 0.94
R5707:Vmn2r83 UTSW 10 79491349 missense possibly damaging 0.53
R5980:Vmn2r83 UTSW 10 79478792 missense probably benign 0.04
R6294:Vmn2r83 UTSW 10 79477854 missense probably damaging 0.99
R6302:Vmn2r83 UTSW 10 79469003 missense possibly damaging 0.95
R6769:Vmn2r83 UTSW 10 79478022 missense probably damaging 1.00
R6986:Vmn2r83 UTSW 10 79480259 missense probably benign
R7221:Vmn2r83 UTSW 10 79480167 missense probably benign 0.02
R7376:Vmn2r83 UTSW 10 79478956 missense probably benign 0.00
R7431:Vmn2r83 UTSW 10 79491472 missense probably damaging 0.99
R7501:Vmn2r83 UTSW 10 79491937 missense probably damaging 0.98
R7526:Vmn2r83 UTSW 10 79491558 missense probably damaging 1.00
R7663:Vmn2r83 UTSW 10 79479122 missense probably damaging 0.98
R7881:Vmn2r83 UTSW 10 79478427 missense probably benign 0.01
R7939:Vmn2r83 UTSW 10 79478817 missense probably damaging 1.00
R8314:Vmn2r83 UTSW 10 79481479 missense possibly damaging 0.76
R8364:Vmn2r83 UTSW 10 79480203 missense probably benign 0.12
X0026:Vmn2r83 UTSW 10 79469015 missense probably benign 0.00
X0026:Vmn2r83 UTSW 10 79478652 missense probably benign
Z1176:Vmn2r83 UTSW 10 79478922 missense possibly damaging 0.74
Posted On2013-06-21