|Institutional Source||Beutler Lab|
|Gene Name||solute carrier family 22 (organic cation transporter), member 14|
|Is this an essential gene?||Probably non essential (E-score: 0.064)|
|Stock #||R6521 (G1)|
|Chromosomal Location||119169455-119365553 bp(-) (GRCm38)|
|Type of Mutation||intron|
|DNA Base Change (assembly)||T to C at 119220769 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000131982 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000170400] [ENSMUST00000173185]|
|Predicted Effect||probably null
|Predicted Effect||probably benign
|Coding Region Coverage||
|Validation Efficiency||100% (48/48)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 3. The encoded protein is a transmembrane protein which is thought to transport small molecules and since this protein is conserved among several species, it is suggested to have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Slc22a14||
(F):5'- GGGTACAGTTTAATCAGTGCTG -3'
(R):5'- CGCACAATGTGTTGGGTAGC -3'
(F):5'- GTAGACAGTACAACTCTGGTCTCAG -3'
(R):5'- CAATGTGTTGGGTAGCTGCTGAC -3'