Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01123:Ros1'

52129

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ros1

Ensembl Gene

ENSMUSG00000019893

Gene Name

Ros1 proto-oncogene

Synonyms

Ros-1, c-ros

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.165) question?

Stock #

IGL01123

Quality Score

Status

Chromosome

Chromosomal Location

52045721-52195244 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 52120809 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Asparagine at position 1256 (Y1256N)

Ref Sequence

ENSEMBL: ENSMUSP00000151720 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000020045] [ENSMUST00000218452] [ENSMUST00000219173] [ENSMUST00000219692]

AlphaFold

Q78DX7

Predicted Effect

probably damaging
Transcript: ENSMUST00000020045
AA Change: Y1277N

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000020045
Gene: ENSMUSG00000019893
AA Change: Y1277N

Domain	Start	End	E-Value	Type
transmembrane domain	7	26	N/A	INTRINSIC
FN3	109	187	1.05e-4	SMART
FN3	205	282	7.45e-10	SMART
LY	369	409	9.17e0	SMART
FN3	568	654	2.24e-4	SMART
LY	734	776	2.28e1	SMART
LY	777	815	4.61e0	SMART
FN3	944	1023	5.53e-4	SMART
FN3	1037	1133	1.07e1	SMART
FN3	1440	1532	1.19e1	SMART
FN3	1551	1637	2.11e0	SMART
FN3	1649	1731	6.8e-4	SMART
FN3	1746	1832	2.7e1	SMART
TyrKc	1938	2208	1.3e-145	SMART
low complexity region	2294	2307	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000117992
AA Change: Y1256N

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000112873
Gene: ENSMUSG00000019893
AA Change: Y1256N

Domain	Start	End	E-Value	Type
transmembrane domain	7	26	N/A	INTRINSIC
FN3	109	187	1.05e-4	SMART
FN3	205	282	7.45e-10	SMART
LY	369	409	9.17e0	SMART
FN3	547	633	2.24e-4	SMART
LY	713	755	2.28e1	SMART
LY	756	794	4.61e0	SMART
FN3	923	1002	5.53e-4	SMART
FN3	1016	1112	1.07e1	SMART
FN3	1419	1511	1.19e1	SMART
FN3	1530	1616	2.11e0	SMART
FN3	1628	1710	6.8e-4	SMART
FN3	1725	1811	2.7e1	SMART
TyrKc	1917	2187	1.3e-145	SMART
low complexity region	2273	2286	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000177378
AA Change: Y1256N

PolyPhen 2 Score 0.861 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000134905
Gene: ENSMUSG00000019893
AA Change: Y1256N

Domain	Start	End	E-Value	Type
transmembrane domain	7	26	N/A	INTRINSIC
FN3	109	187	1.05e-4	SMART
FN3	205	282	7.45e-10	SMART
LY	369	409	9.17e0	SMART
FN3	547	633	2.24e-4	SMART
LY	713	755	2.28e1	SMART
LY	756	794	4.61e0	SMART
FN3	923	1002	5.53e-4	SMART
FN3	1016	1112	1.07e1	SMART
Blast:LY	1190	1236	2e-18	BLAST
FN3	1419	1511	1.19e1	SMART
FN3	1530	1616	2.11e0	SMART
FN3	1628	1710	6.8e-4	SMART
FN3	1725	1811	2.7e1	SMART
transmembrane domain	1832	1854	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000177387

Predicted Effect

probably damaging
Transcript: ENSMUST00000218452
AA Change: Y1256N

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

Predicted Effect

possibly damaging
Transcript: ENSMUST00000219173
AA Change: Y1256N

PolyPhen 2 Score 0.915 (Sensitivity: 0.81; Specificity: 0.94)

Predicted Effect

probably benign
Transcript: ENSMUST00000219692

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for targeted null mutations exhibit male infertility due to impaired sperm maturation in the epididymis. Mutant sperm are capable of fertilization in vitro but not in vivo. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 46 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310057J18Rik	G	T	10: 28,973,938 (GRCm38)	D167E	probably damaging	Het
Aadat	A	T	8: 60,526,614 (GRCm38)	E170V	probably benign	Het
Acsf2	T	C	11: 94,570,450 (GRCm38)	E300G	probably benign	Het
Agbl3	C	T	6: 34,846,976 (GRCm38)	Q859*	probably null	Het
Arhgap11a	T	C	2: 113,834,773 (GRCm38)		probably benign	Het
Arhgef40	C	A	14: 51,994,346 (GRCm38)	Q730K	probably damaging	Het
Armc3	C	T	2: 19,201,805 (GRCm38)	P13L	possibly damaging	Het
B3gnt2	T	A	11: 22,836,490 (GRCm38)	T233S	probably benign	Het
Bnc1	G	A	7: 81,973,707 (GRCm38)	Q591*	probably null	Het
Bsn	A	T	9: 108,115,986 (GRCm38)	F856I	probably damaging	Het
CK137956	T	A	4: 127,935,850 (GRCm38)	T558S	probably benign	Het
Coq8b	G	A	7: 27,240,084 (GRCm38)	V180I	probably damaging	Het
Csmd1	A	T	8: 17,534,928 (GRCm38)	L16Q	possibly damaging	Het
Dhx37	A	G	5: 125,419,088 (GRCm38)	S769P	possibly damaging	Het
Diras1	T	A	10: 81,022,415 (GRCm38)	M1L	probably damaging	Het
Fam161b	A	G	12: 84,357,664 (GRCm38)	W81R	probably benign	Het
Fat4	A	T	3: 38,957,269 (GRCm38)	I2173L	probably benign	Het
Fbn2	T	C	18: 58,104,081 (GRCm38)	T617A	possibly damaging	Het
Gabrq	G	A	X: 72,836,833 (GRCm38)	D311N	probably benign	Het
Isl2	G	T	9: 55,545,462 (GRCm38)	G335C	probably damaging	Het
Kbtbd7	T	C	14: 79,428,612 (GRCm38)	V628A	probably damaging	Het
Kmt2d	T	C	15: 98,837,148 (GRCm38)	M5378V	unknown	Het
Lrrc23	G	T	6: 124,778,819 (GRCm38)	D75E	probably benign	Het
Mab21l3	G	A	3: 101,835,130 (GRCm38)	T38M	probably benign	Het
Matn1	T	C	4: 130,950,011 (GRCm38)	I177T	possibly damaging	Het
Mtor	T	C	4: 148,453,037 (GRCm38)	S60P	probably benign	Het
Naip6	T	C	13: 100,304,438 (GRCm38)	E278G	probably benign	Het
Nsun6	T	C	2: 15,048,978 (GRCm38)	I7V	possibly damaging	Het
Pabpc6	A	T	17: 9,668,147 (GRCm38)	S492T	probably benign	Het
Pakap	C	T	4: 57,757,627 (GRCm38)	Q188*	probably null	Het
Pom121	A	T	5: 135,391,706 (GRCm38)	V287D	unknown	Het
Ptprq	A	T	10: 107,686,218 (GRCm38)	F624Y	probably damaging	Het
Ptprr	A	G	10: 116,188,317 (GRCm38)	T178A	probably benign	Het
Pygm	A	G	19: 6,391,394 (GRCm38)	N473S	probably benign	Het
Scpep1	T	C	11: 88,941,328 (GRCm38)	N192S	possibly damaging	Het
Serpina1f	A	G	12: 103,694,006 (GRCm38)	S6P	possibly damaging	Het
Sgca	T	A	11: 94,972,287 (GRCm38)	Q80L	probably damaging	Het
Skint6	A	G	4: 112,804,682 (GRCm38)	L1235P	possibly damaging	Het
Slc23a2	A	C	2: 132,056,816 (GRCm38)	N600K	probably benign	Het
Spata20	T	C	11: 94,483,395 (GRCm38)	T350A	probably benign	Het
Syne1	G	T	10: 5,344,921 (GRCm38)	Y1227*	probably null	Het
Unc13c	T	C	9: 73,933,197 (GRCm38)	Y124C	probably benign	Het
Usp40	G	A	1: 87,986,123 (GRCm38)	T416I	probably benign	Het
Vmn1r200	T	C	13: 22,395,401 (GRCm38)	W116R	probably benign	Het
Vps4a	T	C	8: 107,039,219 (GRCm38)		probably benign	Het
Zfyve16	A	G	13: 92,492,522 (GRCm38)	V1469A	probably damaging	Het

Other mutations in Ros1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00236:Ros1	APN	10	52,194,890 (GRCm38)	missense	probably benign	0.01
IGL00338:Ros1	APN	10	52,125,811 (GRCm38)	missense	probably benign
IGL00419:Ros1	APN	10	52,091,054 (GRCm38)	missense	probably damaging	0.97
IGL00840:Ros1	APN	10	52,144,873 (GRCm38)	missense	possibly damaging	0.92
IGL00841:Ros1	APN	10	52,144,873 (GRCm38)	missense	possibly damaging	0.92
IGL00951:Ros1	APN	10	52,143,252 (GRCm38)	missense	probably damaging	0.99
IGL01128:Ros1	APN	10	52,142,328 (GRCm38)	nonsense	probably null
IGL01300:Ros1	APN	10	52,101,713 (GRCm38)	missense	probably benign	0.01
IGL01316:Ros1	APN	10	52,087,879 (GRCm38)	critical splice donor site	probably null
IGL01349:Ros1	APN	10	52,051,026 (GRCm38)	missense	probably damaging	0.99
IGL01363:Ros1	APN	10	52,166,142 (GRCm38)	missense	probably damaging	1.00
IGL01457:Ros1	APN	10	52,046,330 (GRCm38)	splice site	probably benign
IGL01532:Ros1	APN	10	52,090,938 (GRCm38)	splice site	probably benign
IGL01585:Ros1	APN	10	52,155,102 (GRCm38)	missense	probably damaging	1.00
IGL01650:Ros1	APN	10	52,154,979 (GRCm38)	missense	probably damaging	0.99
IGL01672:Ros1	APN	10	52,101,803 (GRCm38)	missense	possibly damaging	0.92
IGL01904:Ros1	APN	10	52,077,911 (GRCm38)	missense	probably damaging	0.97
IGL02040:Ros1	APN	10	52,115,922 (GRCm38)	missense	probably damaging	0.99
IGL02053:Ros1	APN	10	52,162,720 (GRCm38)	missense	probably damaging	1.00
IGL02147:Ros1	APN	10	52,120,895 (GRCm38)	missense	probably damaging	1.00
IGL02169:Ros1	APN	10	52,081,957 (GRCm38)	critical splice donor site	probably null
IGL02247:Ros1	APN	10	52,129,581 (GRCm38)	missense	probably damaging	0.99
IGL02262:Ros1	APN	10	52,178,969 (GRCm38)	missense	probably damaging	0.96
IGL02307:Ros1	APN	10	52,128,438 (GRCm38)	missense	possibly damaging	0.53
IGL02398:Ros1	APN	10	52,144,884 (GRCm38)	splice site	probably benign
IGL02525:Ros1	APN	10	52,116,042 (GRCm38)	missense	possibly damaging	0.66
IGL02718:Ros1	APN	10	52,118,232 (GRCm38)	missense	probably damaging	1.00
IGL02721:Ros1	APN	10	52,172,831 (GRCm38)	splice site	probably benign
IGL02808:Ros1	APN	10	52,125,889 (GRCm38)	missense	probably damaging	1.00
IGL03009:Ros1	APN	10	52,145,907 (GRCm38)	missense	probably benign	0.00
IGL03035:Ros1	APN	10	52,075,984 (GRCm38)	splice site	probably benign
IGL03092:Ros1	APN	10	52,098,806 (GRCm38)	missense	probably damaging	0.99
IGL03309:Ros1	APN	10	52,118,261 (GRCm38)	missense	possibly damaging	0.83
IGL03333:Ros1	APN	10	52,155,171 (GRCm38)	missense	probably damaging	1.00
boss	UTSW	10	52,090,995 (GRCm38)	nonsense	probably null
Chuckwagon	UTSW	10	52,118,203 (GRCm38)	missense	probably damaging	1.00
R1005_Ros1_648	UTSW	10	52,128,405 (GRCm38)	splice site	probably benign
R1220_Ros1_012	UTSW	10	52,098,870 (GRCm38)	missense	probably damaging	0.97
R3423_Ros1_122	UTSW	10	52,128,416 (GRCm38)	splice site	probably null
trail	UTSW	10	52,161,895 (GRCm38)	nonsense	probably null
R0049:Ros1	UTSW	10	52,101,761 (GRCm38)	missense	possibly damaging	0.66
R0049:Ros1	UTSW	10	52,101,761 (GRCm38)	missense	possibly damaging	0.66
R0050:Ros1	UTSW	10	52,101,803 (GRCm38)	missense	probably damaging	0.97
R0050:Ros1	UTSW	10	52,101,803 (GRCm38)	missense	probably damaging	0.97
R0057:Ros1	UTSW	10	52,180,191 (GRCm38)	missense	probably benign	0.00
R0057:Ros1	UTSW	10	52,180,191 (GRCm38)	missense	probably benign	0.00
R0106:Ros1	UTSW	10	52,142,267 (GRCm38)	missense	possibly damaging	0.85
R0106:Ros1	UTSW	10	52,142,267 (GRCm38)	missense	possibly damaging	0.85
R0125:Ros1	UTSW	10	52,125,789 (GRCm38)	missense	probably benign	0.38
R0403:Ros1	UTSW	10	52,143,438 (GRCm38)	splice site	probably benign
R0487:Ros1	UTSW	10	52,155,108 (GRCm38)	missense	possibly damaging	0.69
R0502:Ros1	UTSW	10	52,194,823 (GRCm38)	splice site	probably benign
R0557:Ros1	UTSW	10	52,085,263 (GRCm38)	missense	possibly damaging	0.82
R0599:Ros1	UTSW	10	52,123,300 (GRCm38)	missense	probably damaging	1.00
R0620:Ros1	UTSW	10	52,118,348 (GRCm38)	missense	probably damaging	1.00
R0679:Ros1	UTSW	10	52,066,295 (GRCm38)	missense	possibly damaging	0.95
R1005:Ros1	UTSW	10	52,128,405 (GRCm38)	splice site	probably benign
R1073:Ros1	UTSW	10	52,046,125 (GRCm38)	missense	probably damaging	1.00
R1220:Ros1	UTSW	10	52,098,870 (GRCm38)	missense	probably damaging	0.97
R1279:Ros1	UTSW	10	52,142,166 (GRCm38)	missense	possibly damaging	0.81
R1295:Ros1	UTSW	10	52,087,932 (GRCm38)	missense	possibly damaging	0.92
R1336:Ros1	UTSW	10	52,168,662 (GRCm38)	missense	probably damaging	1.00
R1371:Ros1	UTSW	10	52,087,945 (GRCm38)	missense	probably damaging	0.98
R1447:Ros1	UTSW	10	52,098,858 (GRCm38)	missense	possibly damaging	0.66
R1486:Ros1	UTSW	10	52,172,858 (GRCm38)	missense	probably damaging	1.00
R1499:Ros1	UTSW	10	52,098,677 (GRCm38)	missense	possibly damaging	0.92
R1669:Ros1	UTSW	10	52,161,811 (GRCm38)	missense	probably damaging	1.00
R1744:Ros1	UTSW	10	52,123,379 (GRCm38)	missense	probably damaging	0.99
R1759:Ros1	UTSW	10	52,120,826 (GRCm38)	missense	probably damaging	1.00
R1791:Ros1	UTSW	10	52,100,087 (GRCm38)	missense	probably benign	0.00
R1794:Ros1	UTSW	10	52,124,103 (GRCm38)	nonsense	probably null
R2031:Ros1	UTSW	10	52,067,068 (GRCm38)	missense	possibly damaging	0.88
R2115:Ros1	UTSW	10	52,128,555 (GRCm38)	missense	probably benign	0.00
R2219:Ros1	UTSW	10	52,166,079 (GRCm38)	missense	probably damaging	1.00
R2290:Ros1	UTSW	10	52,118,381 (GRCm38)	missense	probably damaging	0.96
R2329:Ros1	UTSW	10	52,162,887 (GRCm38)	missense	probably damaging	1.00
R2371:Ros1	UTSW	10	52,163,895 (GRCm38)	missense	possibly damaging	0.66
R2879:Ros1	UTSW	10	52,172,840 (GRCm38)	critical splice donor site	probably null
R3154:Ros1	UTSW	10	52,050,981 (GRCm38)	missense	probably benign
R3423:Ros1	UTSW	10	52,128,416 (GRCm38)	splice site	probably null
R3424:Ros1	UTSW	10	52,128,416 (GRCm38)	splice site	probably null
R3425:Ros1	UTSW	10	52,128,416 (GRCm38)	splice site	probably null
R3433:Ros1	UTSW	10	52,091,108 (GRCm38)	missense	probably benign	0.45
R3522:Ros1	UTSW	10	52,090,995 (GRCm38)	nonsense	probably null
R3686:Ros1	UTSW	10	52,145,816 (GRCm38)	missense	probably damaging	1.00
R3710:Ros1	UTSW	10	52,161,895 (GRCm38)	nonsense	probably null
R3771:Ros1	UTSW	10	52,128,991 (GRCm38)	missense	probably damaging	0.97
R3808:Ros1	UTSW	10	52,120,848 (GRCm38)	missense	probably benign	0.08
R3930:Ros1	UTSW	10	52,194,848 (GRCm38)	missense	possibly damaging	0.92
R3950:Ros1	UTSW	10	52,066,388 (GRCm38)	missense	probably damaging	1.00
R3981:Ros1	UTSW	10	52,120,878 (GRCm38)	missense	possibly damaging	0.46
R4007:Ros1	UTSW	10	52,118,232 (GRCm38)	missense	probably damaging	1.00
R4346:Ros1	UTSW	10	52,168,609 (GRCm38)	missense	possibly damaging	0.92
R4382:Ros1	UTSW	10	52,120,959 (GRCm38)	missense	possibly damaging	0.46
R4414:Ros1	UTSW	10	52,162,704 (GRCm38)	critical splice donor site	probably null
R4450:Ros1	UTSW	10	52,077,942 (GRCm38)	missense	probably damaging	0.98
R4468:Ros1	UTSW	10	52,118,356 (GRCm38)	missense	probably damaging	1.00
R4569:Ros1	UTSW	10	52,163,994 (GRCm38)	missense	probably damaging	0.99
R4649:Ros1	UTSW	10	52,129,668 (GRCm38)	missense	possibly damaging	0.66
R4684:Ros1	UTSW	10	52,129,096 (GRCm38)	missense	probably damaging	1.00
R4706:Ros1	UTSW	10	52,101,894 (GRCm38)	missense	possibly damaging	0.95
R4731:Ros1	UTSW	10	52,142,229 (GRCm38)	missense	probably damaging	1.00
R4748:Ros1	UTSW	10	52,115,997 (GRCm38)	missense	probably benign	0.00
R4806:Ros1	UTSW	10	52,096,175 (GRCm38)	missense	probably damaging	0.96
R4865:Ros1	UTSW	10	52,172,870 (GRCm38)	missense	probably damaging	0.99
R4973:Ros1	UTSW	10	52,154,991 (GRCm38)	missense	probably damaging	0.98
R5022:Ros1	UTSW	10	52,124,075 (GRCm38)	missense	possibly damaging	0.46
R5033:Ros1	UTSW	10	52,128,416 (GRCm38)	critical splice donor site	probably null
R5082:Ros1	UTSW	10	52,163,941 (GRCm38)	missense	possibly damaging	0.66
R5083:Ros1	UTSW	10	52,163,941 (GRCm38)	missense	possibly damaging	0.66
R5130:Ros1	UTSW	10	52,163,941 (GRCm38)	missense	possibly damaging	0.66
R5269:Ros1	UTSW	10	52,051,008 (GRCm38)	missense	probably damaging	1.00
R5399:Ros1	UTSW	10	52,090,944 (GRCm38)	critical splice donor site	probably null
R5414:Ros1	UTSW	10	52,155,093 (GRCm38)	missense	probably damaging	1.00
R5659:Ros1	UTSW	10	52,143,386 (GRCm38)	missense	possibly damaging	0.92
R5742:Ros1	UTSW	10	52,142,138 (GRCm38)	critical splice donor site	probably null
R5780:Ros1	UTSW	10	52,194,857 (GRCm38)	missense	probably damaging	1.00
R5805:Ros1	UTSW	10	52,123,289 (GRCm38)	missense	probably damaging	1.00
R5843:Ros1	UTSW	10	52,166,197 (GRCm38)	missense	possibly damaging	0.92
R5881:Ros1	UTSW	10	52,181,798 (GRCm38)	missense	probably benign	0.26
R6027:Ros1	UTSW	10	52,163,968 (GRCm38)	missense	possibly damaging	0.82
R6035:Ros1	UTSW	10	52,077,971 (GRCm38)	missense	probably benign
R6035:Ros1	UTSW	10	52,077,971 (GRCm38)	missense	probably benign
R6052:Ros1	UTSW	10	52,163,903 (GRCm38)	missense	probably benign	0.39
R6175:Ros1	UTSW	10	52,101,785 (GRCm38)	missense	probably benign	0.02
R6315:Ros1	UTSW	10	52,118,210 (GRCm38)	missense	probably benign
R6342:Ros1	UTSW	10	52,155,255 (GRCm38)	missense	probably damaging	1.00
R6470:Ros1	UTSW	10	52,166,044 (GRCm38)	critical splice donor site	probably null
R6527:Ros1	UTSW	10	52,143,377 (GRCm38)	missense	possibly damaging	0.66
R6568:Ros1	UTSW	10	52,162,812 (GRCm38)	missense	probably damaging	1.00
R6573:Ros1	UTSW	10	52,155,010 (GRCm38)	missense	possibly damaging	0.84
R6653:Ros1	UTSW	10	52,142,203 (GRCm38)	missense	probably damaging	1.00
R6959:Ros1	UTSW	10	52,163,994 (GRCm38)	missense	probably damaging	0.99
R7011:Ros1	UTSW	10	52,180,176 (GRCm38)	missense	probably damaging	1.00
R7111:Ros1	UTSW	10	52,181,810 (GRCm38)	missense	probably benign	0.02
R7243:Ros1	UTSW	10	52,123,381 (GRCm38)	missense	probably damaging	1.00
R7355:Ros1	UTSW	10	52,166,079 (GRCm38)	missense	probably damaging	1.00
R7385:Ros1	UTSW	10	52,155,126 (GRCm38)	missense	probably benign	0.00
R7460:Ros1	UTSW	10	52,118,203 (GRCm38)	missense	probably damaging	1.00
R7549:Ros1	UTSW	10	52,145,834 (GRCm38)	missense	probably damaging	0.96
R7573:Ros1	UTSW	10	52,169,976 (GRCm38)	missense	probably benign	0.03
R7650:Ros1	UTSW	10	52,046,209 (GRCm38)	missense	probably benign	0.00
R7667:Ros1	UTSW	10	52,163,971 (GRCm38)	missense	probably damaging	1.00
R7696:Ros1	UTSW	10	52,142,283 (GRCm38)	missense	probably damaging	1.00
R7785:Ros1	UTSW	10	52,162,848 (GRCm38)	missense	probably damaging	1.00
R7814:Ros1	UTSW	10	52,096,137 (GRCm38)	missense	probably benign	0.28
R7830:Ros1	UTSW	10	52,154,934 (GRCm38)	missense	probably damaging	0.99
R7832:Ros1	UTSW	10	52,144,861 (GRCm38)	missense	probably damaging	0.99
R7854:Ros1	UTSW	10	52,128,467 (GRCm38)	missense	probably damaging	1.00
R7912:Ros1	UTSW	10	52,168,695 (GRCm38)	missense	probably damaging	1.00
R7972:Ros1	UTSW	10	52,154,830 (GRCm38)	nonsense	probably null
R7993:Ros1	UTSW	10	52,123,347 (GRCm38)	missense	probably benign	0.34
R8036:Ros1	UTSW	10	52,165,343 (GRCm38)	missense	probably benign
R8137:Ros1	UTSW	10	52,125,837 (GRCm38)	missense	possibly damaging	0.87
R8169:Ros1	UTSW	10	52,064,672 (GRCm38)	critical splice donor site	probably null
R8199:Ros1	UTSW	10	52,101,717 (GRCm38)	nonsense	probably null
R8293:Ros1	UTSW	10	52,087,918 (GRCm38)	missense	probably damaging	1.00
R8368:Ros1	UTSW	10	52,064,737 (GRCm38)	missense	probably damaging	1.00
R8406:Ros1	UTSW	10	52,101,845 (GRCm38)	missense	possibly damaging	0.56
R8471:Ros1	UTSW	10	52,120,982 (GRCm38)	missense	probably benign	0.00
R8498:Ros1	UTSW	10	52,178,951 (GRCm38)	missense	probably damaging	0.99
R8532:Ros1	UTSW	10	52,098,756 (GRCm38)	missense	possibly damaging	0.92
R8678:Ros1	UTSW	10	52,087,902 (GRCm38)	missense	probably benign
R8726:Ros1	UTSW	10	52,078,673 (GRCm38)	missense	possibly damaging	0.46
R8789:Ros1	UTSW	10	52,123,232 (GRCm38)	missense	probably damaging	0.99
R8799:Ros1	UTSW	10	52,046,047 (GRCm38)	missense	probably benign	0.08
R8915:Ros1	UTSW	10	52,101,709 (GRCm38)	splice site	probably benign
R8958:Ros1	UTSW	10	52,096,094 (GRCm38)	missense	probably damaging	1.00
R8972:Ros1	UTSW	10	52,123,237 (GRCm38)	missense	probably benign	0.05
R9020:Ros1	UTSW	10	52,154,927 (GRCm38)	missense	probably benign	0.32
R9147:Ros1	UTSW	10	52,050,943 (GRCm38)	missense	probably benign
R9154:Ros1	UTSW	10	52,046,205 (GRCm38)	missense	possibly damaging	0.87
R9189:Ros1	UTSW	10	52,143,406 (GRCm38)	missense	probably damaging	0.99
R9341:Ros1	UTSW	10	52,096,020 (GRCm38)	critical splice donor site	probably null
R9343:Ros1	UTSW	10	52,096,020 (GRCm38)	critical splice donor site	probably null
R9407:Ros1	UTSW	10	52,118,395 (GRCm38)	missense	probably damaging	1.00
R9428:Ros1	UTSW	10	52,081,965 (GRCm38)	missense	probably benign	0.00
R9502:Ros1	UTSW	10	52,124,078 (GRCm38)	missense	probably benign	0.00
R9531:Ros1	UTSW	10	52,130,967 (GRCm38)	missense	probably damaging	1.00
R9546:Ros1	UTSW	10	52,118,119 (GRCm38)	critical splice donor site	probably null
R9562:Ros1	UTSW	10	52,067,074 (GRCm38)	missense	probably damaging	1.00
R9565:Ros1	UTSW	10	52,067,074 (GRCm38)	missense	probably damaging	1.00
R9604:Ros1	UTSW	10	52,118,153 (GRCm38)	missense	probably damaging	1.00
R9645:Ros1	UTSW	10	52,072,052 (GRCm38)	critical splice donor site	probably null
R9658:Ros1	UTSW	10	52,090,973 (GRCm38)	missense	probably damaging	0.99
R9664:Ros1	UTSW	10	52,120,835 (GRCm38)	missense	probably benign	0.18
RF018:Ros1	UTSW	10	52,155,121 (GRCm38)	missense	probably benign
Z1176:Ros1	UTSW	10	52,091,109 (GRCm38)	missense	possibly damaging	0.89
Z1177:Ros1	UTSW	10	52,168,671 (GRCm38)	missense	probably damaging	0.99

Posted On

2013-06-21