Mutagenetix > Incidental Mutation

Incidental Mutation 'R6490:Baz2b'

522725

Institutional Source

Beutler Lab

Gene Symbol

Baz2b

Ensembl Gene

ENSMUSG00000026987

Gene Name

bromodomain adjacent to zinc finger domain, 2B

Synonyms

D2Ertd794e, 5830435C13Rik

MMRRC Submission

044622-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.321) question?

Stock #

R6490 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

59899363-60209839 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 59901729 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Tyrosine at position 2024 (C2024Y)

Ref Sequence

ENSEMBL: ENSMUSP00000108169 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090925] [ENSMUST00000112550]

AlphaFold

A2AUY4

Predicted Effect

probably damaging
Transcript: ENSMUST00000090925
AA Change: C2024Y

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000088443
Gene: ENSMUSG00000026987
AA Change: C2024Y

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	742	1e-12	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000112550
AA Change: C2024Y

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000108169
Gene: ENSMUSG00000026987
AA Change: C2024Y

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	741	3.4e-13	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Pfam:WHIM3	1638	1676	5.1e-14	PFAM
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000130637

SMART Domains

Protein: ENSMUSP00000119690
Gene: ENSMUSG00000026987

Domain	Start	End	E-Value	Type
Pfam:WHIM3	2	37	1.8e-13	PFAM
low complexity region	162	173	N/A	INTRINSIC
PHD	214	253	2.05e-1	SMART

Meta Mutation Damage Score

0.6098

Coding Region Coverage

1x: 99.9%
3x: 99.6%
10x: 98.1%
20x: 94.6%

Validation Efficiency

99% (69/70)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 70 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700018B08Rik	T	G	8: 121,540,554 (GRCm38)	K38T	probably benign	Het
4932415D10Rik	A	T	10: 82,289,304 (GRCm38)	L2624Q	possibly damaging	Het
Abca13	A	G	11: 9,298,661 (GRCm38)	T2803A	probably benign	Het
Adam23	A	G	1: 63,557,454 (GRCm38)	D565G	probably damaging	Het
Adcy3	A	G	12: 4,212,150 (GRCm38)	T1067A	probably damaging	Het
Agrn	A	T	4: 156,167,362 (GRCm38)	Y1921*	probably null	Het
Apc2	A	G	10: 80,313,923 (GRCm38)	N1604D	probably benign	Het
Atxn7	A	T	14: 14,089,446 (GRCm38)	R321*	probably null	Het
Axin1	T	A	17: 26,142,994 (GRCm38)	I104N	probably damaging	Het
Bahd1	T	C	2: 118,917,138 (GRCm38)	S413P	probably benign	Het
Cacna1i	T	A	15: 80,378,247 (GRCm38)	V1388E	probably damaging	Het
Ccdc129	A	G	6: 55,976,420 (GRCm38)	D907G	probably damaging	Het
Ces4a	G	A	8: 105,149,458 (GRCm38)	V544M	probably benign	Het
Cntn3	G	A	6: 102,278,340 (GRCm38)	T199I	probably damaging	Het
Col6a4	A	T	9: 106,074,992 (GRCm38)	L569*	probably null	Het
Ctnna2	A	G	6: 77,143,909 (GRCm38)	I12T	probably benign	Het
Dhx37	A	G	5: 125,419,132 (GRCm38)	M754T	probably benign	Het
Dmrt1	T	A	19: 25,546,031 (GRCm38)	S249T	possibly damaging	Het
Ell	G	T	8: 70,572,903 (GRCm38)	S59I	probably damaging	Het
Fam89a	G	A	8: 124,741,243 (GRCm38)	S110F	probably damaging	Het
Fer1l4	A	C	2: 156,047,914 (GRCm38)	F278V	possibly damaging	Het
Fyn	T	C	10: 39,551,402 (GRCm38)	I427T	probably damaging	Het
Galnt14	T	C	17: 73,525,370 (GRCm38)	D250G	probably damaging	Het
Glp1r	T	C	17: 30,924,572 (GRCm38)	V194A	probably damaging	Het
Glt1d1	T	A	5: 127,644,296 (GRCm38)		probably null	Het
Gm7995	A	G	14: 42,311,370 (GRCm38)	K69R	probably benign	Het
Grip1	A	G	10: 119,986,424 (GRCm38)	T379A	possibly damaging	Het
Gtpbp2	G	T	17: 46,168,221 (GRCm38)	A570S	probably benign	Het
Hmcn1	T	C	1: 150,583,278 (GRCm38)	I5192V	probably benign	Het
Igfl3	A	T	7: 18,179,919 (GRCm38)	I65F	possibly damaging	Het
Igsf10	G	T	3: 59,329,571 (GRCm38)	T1063K	probably benign	Het
Itfg1	A	G	8: 85,740,301 (GRCm38)	V381A	probably benign	Het
Jmjd8	T	A	17: 25,829,112 (GRCm38)	V16E	probably benign	Het
Kank1	A	G	19: 25,410,085 (GRCm38)	Y374C	probably damaging	Het
Kcnma1	C	T	14: 23,336,097 (GRCm38)	V891I	possibly damaging	Het
Kif20a	C	A	18: 34,629,490 (GRCm38)	T472K	possibly damaging	Het
Klhl32	A	T	4: 24,711,578 (GRCm38)		probably benign	Het
Lrrc37a	A	G	11: 103,456,660 (GRCm38)	S3070P	unknown	Het
Mettl21e	T	G	1: 44,210,265 (GRCm38)	Y77S	probably damaging	Het
Mlst8	G	T	17: 24,477,961 (GRCm38)	D82E	probably benign	Het
Mrgprx2	A	T	7: 48,482,869 (GRCm38)	L67Q	probably damaging	Het
Mylk	T	A	16: 34,929,867 (GRCm38)	L1192Q	possibly damaging	Het
Myt1l	A	T	12: 29,832,366 (GRCm38)	Y520F	unknown	Het
Naip2	A	T	13: 100,160,685 (GRCm38)	W948R	probably benign	Het
Nlrp9a	A	C	7: 26,550,886 (GRCm38)	K25N	probably damaging	Het
Nsd3	T	C	8: 25,714,185 (GRCm38)	C414R	probably damaging	Het
Oit3	A	T	10: 59,438,552 (GRCm38)	V142D	possibly damaging	Het
Olfr171	C	T	16: 19,624,444 (GRCm38)	V219M	probably benign	Het
P2ry6	T	C	7: 100,938,373 (GRCm38)	T260A	probably damaging	Het
Papola	A	G	12: 105,804,937 (GRCm38)	Q87R	probably benign	Het
Pla2g4a	T	A	1: 149,851,335 (GRCm38)	R557*	probably null	Het
Rgs13	G	T	1: 144,140,838 (GRCm38)	H56N	probably damaging	Het
Sbf1	T	C	15: 89,304,908 (GRCm38)	S537G	probably benign	Het
Sntg1	A	C	1: 8,583,284 (GRCm38)	L243R	possibly damaging	Het
Stam2	T	C	2: 52,720,942 (GRCm38)	T23A	probably benign	Het
Tbl1xr1	C	A	3: 22,203,977 (GRCm38)	H467Q	probably damaging	Het
Tmem131l	A	G	3: 83,913,280 (GRCm38)	S1222P	possibly damaging	Het
Tmem43	T	A	6: 91,486,880 (GRCm38)	I379N	possibly damaging	Het
Tmem43	G	T	6: 91,478,777 (GRCm38)	Q123H	probably damaging	Het
Trim43c	A	T	9: 88,844,950 (GRCm38)	I277F	possibly damaging	Het
Ttn	A	G	2: 76,872,867 (GRCm38)		probably benign	Het
Vmn1r75	T	A	7: 11,881,076 (GRCm38)	V245D	probably damaging	Het
Vmn2r111	T	C	17: 22,559,051 (GRCm38)	N549S	possibly damaging	Het
Vps53	A	T	11: 76,077,055 (GRCm38)	M414K	probably benign	Het
Wrn	T	G	8: 33,319,220 (GRCm38)	L249F	probably benign	Het
Zc3h13	TGATGTCCGGGATGTCCGGGATGTCCGGGATGTCCGGGATGT	TGATGTCCGGGATGTCCGGGATGTCCGGGATGT	14: 75,323,558 (GRCm38)		probably benign	Het
Zfp454	T	C	11: 50,874,123 (GRCm38)	N161D	probably benign	Het
Zfp619	G	A	7: 39,534,162 (GRCm38)	G60R	probably benign	Het
Zfp623	T	A	15: 75,948,459 (GRCm38)	H421Q	probably damaging	Het
Zfp827	A	G	8: 79,189,977 (GRCm38)		probably benign	Het

Other mutations in Baz2b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00430:Baz2b	APN	2	59,912,795 (GRCm38)	missense	probably benign	0.02
IGL00476:Baz2b	APN	2	59,913,739 (GRCm38)	missense	probably benign	0.06
IGL00489:Baz2b	APN	2	59,957,675 (GRCm38)	nonsense	probably null
IGL00514:Baz2b	APN	2	59,962,477 (GRCm38)	missense	probably benign	0.11
IGL00678:Baz2b	APN	2	60,006,183 (GRCm38)	missense	unknown
IGL01348:Baz2b	APN	2	59,933,687 (GRCm38)	missense	possibly damaging	0.95
IGL01354:Baz2b	APN	2	59,968,889 (GRCm38)	missense	probably benign	0.18
IGL01924:Baz2b	APN	2	59,935,271 (GRCm38)	missense	probably damaging	1.00
IGL02125:Baz2b	APN	2	59,968,640 (GRCm38)	missense	probably benign	0.12
IGL02314:Baz2b	APN	2	59,962,227 (GRCm38)	missense	probably benign
IGL02370:Baz2b	APN	2	59,923,589 (GRCm38)	missense	possibly damaging	0.77
IGL02473:Baz2b	APN	2	59,960,063 (GRCm38)	missense	probably benign	0.40
IGL02499:Baz2b	APN	2	59,901,496 (GRCm38)	missense	possibly damaging	0.60
IGL02609:Baz2b	APN	2	59,917,369 (GRCm38)	missense	possibly damaging	0.77
IGL02705:Baz2b	APN	2	59,948,260 (GRCm38)	missense	possibly damaging	0.92
IGL02711:Baz2b	APN	2	59,917,505 (GRCm38)	unclassified	probably benign
IGL02716:Baz2b	APN	2	59,962,524 (GRCm38)	missense	possibly damaging	0.53
IGL02724:Baz2b	APN	2	59,977,374 (GRCm38)	missense	possibly damaging	0.70
IGL02750:Baz2b	APN	2	59,968,658 (GRCm38)	missense	possibly damaging	0.73
IGL02869:Baz2b	APN	2	59,977,528 (GRCm38)	missense	probably benign	0.00
IGL02886:Baz2b	APN	2	59,957,743 (GRCm38)	splice site	probably null
IGL02892:Baz2b	APN	2	59,900,736 (GRCm38)	missense	probably damaging	1.00
IGL03132:Baz2b	APN	2	59,907,753 (GRCm38)	splice site	probably benign
IGL03183:Baz2b	APN	2	59,903,296 (GRCm38)	missense	probably benign	0.10
IGL03197:Baz2b	APN	2	59,901,554 (GRCm38)	missense	possibly damaging	0.74
R0054:Baz2b	UTSW	2	59,932,166 (GRCm38)	missense	probably damaging	1.00
R0054:Baz2b	UTSW	2	59,932,166 (GRCm38)	missense	probably damaging	1.00
R0122:Baz2b	UTSW	2	59,913,619 (GRCm38)	splice site	probably null
R0136:Baz2b	UTSW	2	59,901,954 (GRCm38)	missense	probably benign	0.22
R0144:Baz2b	UTSW	2	59,907,495 (GRCm38)	missense	probably damaging	0.98
R0403:Baz2b	UTSW	2	59,969,377 (GRCm38)	missense	possibly damaging	0.70
R0498:Baz2b	UTSW	2	59,901,996 (GRCm38)	unclassified	probably benign
R0528:Baz2b	UTSW	2	59,936,739 (GRCm38)	missense	probably damaging	1.00
R1025:Baz2b	UTSW	2	59,962,482 (GRCm38)	missense	probably benign	0.06
R1470:Baz2b	UTSW	2	59,978,546 (GRCm38)	missense	possibly damaging	0.53
R1470:Baz2b	UTSW	2	59,978,546 (GRCm38)	missense	possibly damaging	0.53
R1510:Baz2b	UTSW	2	59,922,209 (GRCm38)	missense	probably damaging	1.00
R1511:Baz2b	UTSW	2	59,962,024 (GRCm38)	missense	probably benign	0.12
R1514:Baz2b	UTSW	2	59,962,326 (GRCm38)	missense	probably benign	0.13
R1519:Baz2b	UTSW	2	59,948,254 (GRCm38)	missense	possibly damaging	0.50
R1523:Baz2b	UTSW	2	59,968,637 (GRCm38)	missense	possibly damaging	0.47
R1630:Baz2b	UTSW	2	60,006,130 (GRCm38)	missense	unknown
R1641:Baz2b	UTSW	2	59,912,890 (GRCm38)	missense	probably damaging	0.99
R1674:Baz2b	UTSW	2	59,912,992 (GRCm38)	missense	possibly damaging	0.53
R1778:Baz2b	UTSW	2	60,006,136 (GRCm38)	missense	unknown
R1826:Baz2b	UTSW	2	59,968,733 (GRCm38)	missense	probably benign	0.12
R1835:Baz2b	UTSW	2	59,901,819 (GRCm38)	missense	probably benign	0.02
R1954:Baz2b	UTSW	2	59,968,743 (GRCm38)	missense	probably benign	0.12
R1981:Baz2b	UTSW	2	59,923,680 (GRCm38)	missense	possibly damaging	0.95
R2029:Baz2b	UTSW	2	59,912,723 (GRCm38)	unclassified	probably benign
R2567:Baz2b	UTSW	2	59,913,911 (GRCm38)	missense	possibly damaging	0.82
R2842:Baz2b	UTSW	2	59,913,004 (GRCm38)	missense	probably benign	0.27
R2848:Baz2b	UTSW	2	59,924,666 (GRCm38)	missense	possibly damaging	0.64
R3809:Baz2b	UTSW	2	59,968,896 (GRCm38)	missense	probably benign	0.12
R3935:Baz2b	UTSW	2	59,912,761 (GRCm38)	missense	possibly damaging	0.81
R3936:Baz2b	UTSW	2	59,912,761 (GRCm38)	missense	possibly damaging	0.81
R4072:Baz2b	UTSW	2	59,912,573 (GRCm38)	splice site	probably null
R4182:Baz2b	UTSW	2	60,098,457 (GRCm38)	intron	probably benign
R4255:Baz2b	UTSW	2	59,920,572 (GRCm38)	unclassified	probably benign
R4359:Baz2b	UTSW	2	59,901,613 (GRCm38)	missense	possibly damaging	0.87
R4716:Baz2b	UTSW	2	59,969,255 (GRCm38)	missense	probably benign	0.06
R4743:Baz2b	UTSW	2	59,913,911 (GRCm38)	missense	probably benign	0.01
R4772:Baz2b	UTSW	2	59,958,451 (GRCm38)	missense	probably damaging	0.96
R4858:Baz2b	UTSW	2	59,907,743 (GRCm38)	missense	probably benign
R4868:Baz2b	UTSW	2	59,924,882 (GRCm38)	missense	possibly damaging	0.65
R4872:Baz2b	UTSW	2	59,942,759 (GRCm38)	splice site	probably null
R4889:Baz2b	UTSW	2	59,936,726 (GRCm38)	missense	probably damaging	1.00
R4890:Baz2b	UTSW	2	59,926,039 (GRCm38)	missense	probably damaging	0.99
R4914:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R4915:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R4918:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R5027:Baz2b	UTSW	2	60,098,644 (GRCm38)	intron	probably benign
R5031:Baz2b	UTSW	2	59,912,807 (GRCm38)	missense	probably benign	0.00
R5082:Baz2b	UTSW	2	59,901,491 (GRCm38)	nonsense	probably null
R5133:Baz2b	UTSW	2	59,962,024 (GRCm38)	missense	probably benign	0.12
R5276:Baz2b	UTSW	2	59,962,614 (GRCm38)	missense	probably benign	0.40
R5279:Baz2b	UTSW	2	59,932,152 (GRCm38)	missense	probably damaging	1.00
R5294:Baz2b	UTSW	2	59,978,602 (GRCm38)	missense	probably benign	0.11
R5447:Baz2b	UTSW	2	59,913,988 (GRCm38)	missense	probably damaging	0.99
R5903:Baz2b	UTSW	2	59,959,889 (GRCm38)	missense	probably damaging	0.99
R5910:Baz2b	UTSW	2	59,977,426 (GRCm38)	missense	possibly damaging	0.88
R6140:Baz2b	UTSW	2	59,912,527 (GRCm38)	missense	probably damaging	0.99
R6195:Baz2b	UTSW	2	59,907,511 (GRCm38)	missense	possibly damaging	0.89
R6199:Baz2b	UTSW	2	59,978,675 (GRCm38)	missense	probably benign	0.00
R6208:Baz2b	UTSW	2	59,924,806 (GRCm38)	missense	probably damaging	1.00
R6233:Baz2b	UTSW	2	59,907,511 (GRCm38)	missense	possibly damaging	0.89
R6276:Baz2b	UTSW	2	59,948,223 (GRCm38)	missense	probably damaging	1.00
R6324:Baz2b	UTSW	2	59,906,948 (GRCm38)	missense	probably damaging	1.00
R6578:Baz2b	UTSW	2	59,969,279 (GRCm38)	missense	possibly damaging	0.47
R6720:Baz2b	UTSW	2	59,924,890 (GRCm38)	missense	probably damaging	1.00
R6760:Baz2b	UTSW	2	59,962,432 (GRCm38)	missense	probably benign	0.40
R6836:Baz2b	UTSW	2	59,917,425 (GRCm38)	missense	probably damaging	1.00
R6859:Baz2b	UTSW	2	59,901,530 (GRCm38)	missense	probably benign	0.01
R6880:Baz2b	UTSW	2	59,912,939 (GRCm38)	missense	probably damaging	0.99
R6916:Baz2b	UTSW	2	59,968,776 (GRCm38)	missense	probably benign
R6978:Baz2b	UTSW	2	59,907,715 (GRCm38)	missense	possibly damaging	0.84
R7037:Baz2b	UTSW	2	59,933,670 (GRCm38)	critical splice donor site	probably null
R7112:Baz2b	UTSW	2	59,962,184 (GRCm38)	missense	possibly damaging	0.53
R7117:Baz2b	UTSW	2	59,912,497 (GRCm38)	missense
R7198:Baz2b	UTSW	2	59,962,206 (GRCm38)	missense	probably benign	0.00
R7270:Baz2b	UTSW	2	59,962,492 (GRCm38)	missense	possibly damaging	0.96
R7282:Baz2b	UTSW	2	59,920,437 (GRCm38)	missense	probably benign	0.17
R7464:Baz2b	UTSW	2	59,977,448 (GRCm38)	missense	possibly damaging	0.53
R7609:Baz2b	UTSW	2	59,962,473 (GRCm38)	missense	probably benign	0.40
R7703:Baz2b	UTSW	2	59,917,425 (GRCm38)	missense	probably damaging	1.00
R7850:Baz2b	UTSW	2	59,936,716 (GRCm38)	missense	probably damaging	0.98
R7851:Baz2b	UTSW	2	59,936,716 (GRCm38)	missense	probably damaging	0.98
R7988:Baz2b	UTSW	2	59,962,141 (GRCm38)	missense	possibly damaging	0.53
R8079:Baz2b	UTSW	2	59,900,768 (GRCm38)	missense	probably damaging	1.00
R8084:Baz2b	UTSW	2	59,962,236 (GRCm38)	missense	probably benign
R8343:Baz2b	UTSW	2	59,901,514 (GRCm38)	missense	probably damaging	1.00
R8348:Baz2b	UTSW	2	59,911,793 (GRCm38)	missense
R8438:Baz2b	UTSW	2	59,917,484 (GRCm38)	nonsense	probably null
R8448:Baz2b	UTSW	2	59,911,793 (GRCm38)	missense
R8511:Baz2b	UTSW	2	59,901,814 (GRCm38)	missense	probably benign
R8893:Baz2b	UTSW	2	59,924,805 (GRCm38)	missense	probably damaging	0.96
R8947:Baz2b	UTSW	2	59,948,239 (GRCm38)	missense	probably benign	0.06
R8998:Baz2b	UTSW	2	59,969,264 (GRCm38)	missense	probably benign	0.02
R9241:Baz2b	UTSW	2	59,913,649 (GRCm38)	missense	probably benign	0.01
R9245:Baz2b	UTSW	2	59,912,987 (GRCm38)	missense	probably benign
R9577:Baz2b	UTSW	2	59,978,687 (GRCm38)	missense	probably benign	0.06
R9581:Baz2b	UTSW	2	59,968,956 (GRCm38)	missense	probably benign
R9601:Baz2b	UTSW	2	59,901,503 (GRCm38)	missense	possibly damaging	0.66
R9613:Baz2b	UTSW	2	59,901,480 (GRCm38)	missense	probably benign	0.09
R9639:Baz2b	UTSW	2	59,901,484 (GRCm38)	missense	probably benign	0.01
X0011:Baz2b	UTSW	2	59,977,361 (GRCm38)	missense	possibly damaging	0.53
X0053:Baz2b	UTSW	2	59,900,675 (GRCm38)	missense	probably damaging	1.00
X0064:Baz2b	UTSW	2	59,969,282 (GRCm38)	missense	probably benign
Z1088:Baz2b	UTSW	2	59,960,015 (GRCm38)	missense	probably damaging	1.00
Z1177:Baz2b	UTSW	2	59,977,520 (GRCm38)	missense	probably benign	0.01
Z1188:Baz2b	UTSW	2	59,977,405 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- AGCCGGGTACGAGTTTCAAG -3'
(R):5'- GCAGCCGCTTTCTTATACAC -3'

Sequencing Primer
(F):5'- CCGGGTACGAGTTTCAAGTTCAC -3'
(R):5'- CTTTTTAATTAAAGGCAAGCGGC -3'

Posted On

2018-06-06