Incidental Mutation 'IGL01096:Tmem101'
ID52277
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tmem101
Ensembl Gene ENSMUSG00000020921
Gene Nametransmembrane protein 101
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.157) question?
Stock #IGL01096
Quality Score
Status
Chromosome11
Chromosomal Location102152546-102156404 bp(-) (GRCm38)
Type of Mutationsplice site (5 bp from exon)
DNA Base Change (assembly) C to A at 102154552 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000021296 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000021296]
Predicted Effect probably null
Transcript: ENSMUST00000021296
SMART Domains Protein: ENSMUSP00000021296
Gene: ENSMUSG00000020921

DomainStartEndE-ValueType
Pfam:TMEM101 8 256 9.9e-122 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000136434
Predicted Effect noncoding transcript
Transcript: ENSMUST00000143986
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrg3 A T 8: 95,039,593 M351L possibly damaging Het
Alk T C 17: 71,921,896 K725E possibly damaging Het
Dspp T A 5: 104,175,367 H125Q possibly damaging Het
Elmo2 A T 2: 165,296,987 probably benign Het
Erg A G 16: 95,390,053 probably benign Het
Fam20c A G 5: 138,809,155 E513G possibly damaging Het
Gatsl3 A C 11: 4,221,850 E309A probably damaging Het
Gm9839 G T 1: 32,520,836 T55N possibly damaging Het
Gpd2 A T 2: 57,338,867 M228L probably damaging Het
Hp A T 8: 109,575,401 M305K probably benign Het
Ifng T A 10: 118,445,269 probably benign Het
Igkv9-123 T C 6: 67,954,465 D39G possibly damaging Het
Melk T A 4: 44,347,262 F431I probably benign Het
Olfr1180 A G 2: 88,411,791 M289T probably damaging Het
Olfr1335 A G 4: 118,809,456 V136A probably damaging Het
Olfr536 A T 7: 140,504,184 S92T probably damaging Het
Olfr639 A C 7: 104,012,114 L196W probably damaging Het
Olfr944 G A 9: 39,218,116 G253D probably damaging Het
Pappa T C 4: 65,189,316 Y655H probably damaging Het
Prss58 A T 6: 40,895,465 I208N probably damaging Het
Ryr2 T A 13: 11,703,544 I2720F probably damaging Het
Slc13a1 G T 6: 24,104,077 T322K probably damaging Het
Spag17 T C 3: 100,063,375 F1292L probably benign Het
Tbx5 A G 5: 119,883,026 T366A probably benign Het
Tmeff2 G A 1: 50,930,546 probably benign Het
Tpp2 C A 1: 43,960,888 P389T probably damaging Het
Tyk2 A G 9: 21,108,863 Y1000H probably damaging Het
Ush2a C A 1: 188,678,377 N2407K probably damaging Het
Vmn1r94 C T 7: 20,167,636 V248I probably damaging Het
Vmn2r12 T A 5: 109,086,259 I696F probably damaging Het
Vmn2r83 A G 10: 79,477,828 E90G probably damaging Het
Washc5 T C 15: 59,350,211 probably benign Het
Wee2 A G 6: 40,463,253 E445G probably benign Het
Zfp518b T C 5: 38,672,788 T625A probably benign Het
Other mutations in Tmem101
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01085:Tmem101 APN 11 102154660 missense probably damaging 0.99
IGL01593:Tmem101 APN 11 102155878 missense probably damaging 1.00
IGL01814:Tmem101 APN 11 102153458 missense possibly damaging 0.58
IGL02451:Tmem101 APN 11 102153293 missense probably damaging 1.00
IGL03238:Tmem101 APN 11 102155785 missense probably damaging 1.00
R0462:Tmem101 UTSW 11 102155867 missense probably benign 0.08
R0848:Tmem101 UTSW 11 102155866 missense possibly damaging 0.65
R1465:Tmem101 UTSW 11 102153329 missense probably damaging 0.97
R1465:Tmem101 UTSW 11 102153329 missense probably damaging 0.97
R1722:Tmem101 UTSW 11 102154693 missense probably damaging 1.00
R1928:Tmem101 UTSW 11 102153396 missense probably benign
R2082:Tmem101 UTSW 11 102153377 missense probably benign 0.17
R4577:Tmem101 UTSW 11 102155837 missense possibly damaging 0.48
R4724:Tmem101 UTSW 11 102153443 missense probably benign 0.32
R4729:Tmem101 UTSW 11 102156329 missense probably benign 0.25
R5146:Tmem101 UTSW 11 102154624 missense probably benign
R5184:Tmem101 UTSW 11 102156233 missense possibly damaging 0.78
R7381:Tmem101 UTSW 11 102153350 missense possibly damaging 0.91
Posted On2013-06-21