Incidental Mutation 'IGL01118:Gm21319'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm21319
Ensembl Gene ENSMUSG00000095724
Gene Namepredicted gene, 21319
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.131) question?
Stock #IGL01118
Quality Score
Chromosomal Location87772425-87775755 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 87773442 bp
Amino Acid Change Asparagine to Tyrosine at position 116 (N116Y)
Ref Sequence ENSEMBL: ENSMUSP00000126351 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000164517]
Predicted Effect probably damaging
Transcript: ENSMUST00000164517
AA Change: N116Y

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
SMART Domains Protein: ENSMUSP00000126351
Gene: ENSMUSG00000095724
AA Change: N116Y

low complexity region 3 19 N/A INTRINSIC
eIF1a 28 110 6.17e-44 SMART
low complexity region 125 144 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000222683
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700006A11Rik C T 3: 124,401,409 R539Q probably benign Het
Abcb1a G A 5: 8,674,687 R40H probably damaging Het
Acan T A 7: 79,098,653 S1057R possibly damaging Het
Ahnak A T 19: 9,012,578 D3742V probably damaging Het
Amdhd1 A T 10: 93,531,568 D241E probably benign Het
Cntn5 T C 9: 9,831,560 Y605C possibly damaging Het
Dgcr14 A T 16: 17,902,932 I350N probably damaging Het
Dnmt3l T C 10: 78,057,286 F299S probably damaging Het
G6pd2 A T 5: 61,810,063 M394L probably benign Het
Gm9839 A T 1: 32,519,843 M386K probably benign Het
Gtf2h3 T C 5: 124,595,668 V268A probably damaging Het
Hgs T C 11: 120,475,214 V195A probably damaging Het
Igkv3-2 A T 6: 70,698,994 S96C probably damaging Het
Mgl2 A G 11: 70,134,189 E12G probably benign Het
Mup11 A T 4: 60,659,780 F153I probably damaging Het
Nf1 T A 11: 79,546,986 C2057S probably damaging Het
Nkrf A G X: 36,888,757 F624S probably damaging Het
Noto T C 6: 85,424,210 S74P probably benign Het
Olfr1090 A G 2: 86,753,970 I256T probably benign Het
Pax8 T C 2: 24,442,932 probably benign Het
Psg28 A T 7: 18,428,092 V162D probably damaging Het
Rai1 T C 11: 60,187,438 F776S probably damaging Het
Taar8a A T 10: 24,076,861 H121L probably damaging Het
Tas2r113 A G 6: 132,893,315 N102S probably benign Het
Trpm1 A G 7: 64,235,824 T863A probably benign Het
Ttf2 A G 3: 100,967,097 probably benign Het
Wdr62 T C 7: 30,242,781 H611R probably damaging Het
Wdr90 A T 17: 25,854,687 L762Q probably damaging Het
Yeats2 T G 16: 20,186,304 S364A probably damaging Het
Zdhhc15 G T X: 104,598,106 Q82K probably benign Het
Other mutations in Gm21319
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0089:Gm21319 UTSW 12 87773513 missense probably damaging 1.00
R0559:Gm21319 UTSW 12 87773453 missense probably benign
R1185:Gm21319 UTSW 12 87773708 missense probably benign 0.14
R3800:Gm21319 UTSW 12 87773721 missense possibly damaging 0.95
R4531:Gm21319 UTSW 12 87773544 nonsense probably null
R5013:Gm21319 UTSW 12 87773742 nonsense probably null
R5817:Gm21319 UTSW 12 87773431 missense probably benign 0.01
R7137:Gm21319 UTSW 12 87773546 missense possibly damaging 0.90
R7187:Gm21319 UTSW 12 87773938 start gained probably benign
R7403:Gm21319 UTSW 12 87773544 missense probably benign 0.10
R7505:Gm21319 UTSW 12 87773500 missense probably benign 0.20
Posted On2013-06-21