Incidental Mutation 'IGL01062:Gm3173'
ID52639
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm3173
Ensembl Gene ENSMUSG00000079386
Gene Namepredicted gene 3173
Synonyms
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.311) question?
Stock #IGL01062
Quality Score
Status
Chromosome14
Chromosomal Location4430992-4519452 bp(+) (GRCm38)
Type of Mutationcritical splice donor site (2 bp from exon)
DNA Base Change (assembly) T to C at 4514887 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000108396 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000112776] [ENSMUST00000164603] [ENSMUST00000166848]
Predicted Effect probably null
Transcript: ENSMUST00000112776
SMART Domains Protein: ENSMUSP00000108396
Gene: ENSMUSG00000079386

DomainStartEndE-ValueType
Pfam:Takusan 1 73 3e-21 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000164603
SMART Domains Protein: ENSMUSP00000125850
Gene: ENSMUSG00000079386

DomainStartEndE-ValueType
Pfam:Takusan 1 74 2e-27 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000166848
SMART Domains Protein: ENSMUSP00000127993
Gene: ENSMUSG00000079386

DomainStartEndE-ValueType
Pfam:Takusan 1 74 1.4e-27 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1110017D15Rik T A 4: 41,511,433 E93D probably damaging Het
Aen G A 7: 78,907,302 M299I probably damaging Het
Amer3 A G 1: 34,586,739 K20E probably damaging Het
Arhgap31 A G 16: 38,601,456 L1416P probably damaging Het
Avpr1a G A 10: 122,449,529 C242Y probably damaging Het
Bclaf3 T C X: 159,553,419 Y281H probably benign Het
Cdc14a T A 3: 116,274,712 probably benign Het
Cfap206 C T 4: 34,721,562 S162N probably damaging Het
Cntn4 T C 6: 106,618,278 probably benign Het
Cyp3a44 T A 5: 145,794,339 D217V possibly damaging Het
Eprs A G 1: 185,379,615 E274G probably benign Het
Ercc6l2 G T 13: 63,847,454 Q354H probably null Het
Glb1l A T 1: 75,201,238 I392N probably damaging Het
Grasp A G 15: 101,228,896 probably benign Het
Hadh C T 3: 131,240,991 V219M probably damaging Het
Hspb9 A G 11: 100,713,935 H29R possibly damaging Het
Iqgap3 G T 3: 88,110,122 V240L probably benign Het
Jmjd1c T C 10: 67,226,715 S1616P probably damaging Het
Knl1 A G 2: 119,076,980 I1662V probably benign Het
Mapre3 A G 5: 30,864,896 I236V probably benign Het
Med17 T C 9: 15,279,621 E58G probably benign Het
Myh6 T C 14: 54,952,292 E1099G probably damaging Het
Myt1 T A 2: 181,797,729 V348D probably damaging Het
Nat10 A T 2: 103,743,048 I368N probably damaging Het
Nol6 T C 4: 41,118,205 I811V probably benign Het
Oas1d C A 5: 120,919,064 Y244* probably null Het
Olfr49 A T 14: 54,282,724 M57K probably damaging Het
Osbpl1a A G 18: 12,905,075 V273A probably benign Het
Pigw T C 11: 84,877,943 R187G probably benign Het
Plekhg5 G A 4: 152,108,496 D603N probably damaging Het
Ptprk T C 10: 28,580,418 V1058A probably damaging Het
Robo4 G A 9: 37,406,000 S537N probably benign Het
Rptn T A 3: 93,397,182 F607L probably benign Het
Sall1 A G 8: 89,033,344 V44A probably damaging Het
Sh3bp4 C A 1: 89,143,960 Q177K probably benign Het
Srrt C A 5: 137,296,307 G779V probably damaging Het
Tex21 T C 12: 76,198,944 D526G probably benign Het
Tmem57 A T 4: 134,833,297 V125E probably damaging Het
Ttc37 T A 13: 76,155,462 L1225* probably null Het
Vmn1r10 A G 6: 57,113,836 S138G possibly damaging Het
Yars2 C T 16: 16,306,542 R338* probably null Het
Zfp454 T C 11: 50,874,206 E22G probably benign Het
Zzef1 T A 11: 72,874,969 C1441S probably benign Het
Other mutations in Gm3173
AlleleSourceChrCoordTypePredicted EffectPPH Score
R4334:Gm3173 UTSW 14 4514779 missense possibly damaging 0.60
R6021:Gm3173 UTSW 14 4514873 missense probably damaging 1.00
R6545:Gm3173 UTSW 14 4514810 missense possibly damaging 0.88
Posted On2013-06-21