Incidental Mutation 'IGL01064:Gm17654'
ID52644
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm17654
Ensembl Gene ENSMUSG00000095743
Gene Namepredicted gene, 17654
Synonyms
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.348) question?
Stock #IGL01064
Quality Score
Status
Chromosome14
Chromosomal Location43573843-43579146 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 43578998 bp
ZygosityHeterozygous
Amino Acid Change Histidine to Glutamine at position 49 (H49Q)
Gene Model predicted gene model for transcript(s):
Predicted Effect unknown
Transcript: ENSMUST00000166110
AA Change: H49Q
SMART Domains Protein: ENSMUSP00000130744
Gene: ENSMUSG00000095743
AA Change: H49Q

DomainStartEndE-ValueType
Pfam:Takusan 57 137 1e-26 PFAM
coiled coil region 164 186 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca13 A T 11: 9,483,855 T4137S probably benign Het
Abcb1a T C 5: 8,732,388 Y924H possibly damaging Het
Ash1l T G 3: 89,072,484 C2772G probably damaging Het
Cfap206 C T 4: 34,721,562 S162N probably damaging Het
Cpne6 T C 14: 55,512,730 F106S probably damaging Het
Cysltr1 A T X: 106,578,736 I48N probably damaging Het
Dsg1a A T 18: 20,340,206 I779F probably damaging Het
Fpr-rs4 T A 17: 18,022,517 L262H probably damaging Het
Gart G A 16: 91,623,007 R871C probably damaging Het
Get4 C T 5: 139,252,522 R20C probably damaging Het
Gm13030 G A 4: 138,873,558 probably benign Het
Gpnmb A G 6: 49,055,659 I506V probably benign Het
Ist1 T C 8: 109,682,611 I86V probably damaging Het
Kcnip1 C T 11: 33,633,192 D198N probably damaging Het
Kif5c A G 2: 49,694,816 I184V possibly damaging Het
Mink1 A T 11: 70,603,481 M236L probably benign Het
Muc5ac A T 7: 141,807,473 N1507I probably benign Het
Nrxn2 G T 19: 6,517,053 E1326D probably damaging Het
Olfr1329 A T 4: 118,916,894 M191K possibly damaging Het
Olfr1469 T C 19: 13,411,226 I219T probably benign Het
Olfr635 A T 7: 103,979,792 Y200F probably benign Het
Patj T C 4: 98,496,973 S326P possibly damaging Het
Pdha2 T C 3: 141,211,015 H244R possibly damaging Het
Pkhd1 C T 1: 20,534,530 probably benign Het
Ptk7 A T 17: 46,573,566 L746* probably null Het
Rad54b G A 4: 11,604,866 G438D probably damaging Het
Rbm27 T C 18: 42,319,814 V536A possibly damaging Het
Rundc3b T A 5: 8,569,553 M135L probably damaging Het
Sorcs2 T C 5: 36,065,352 Y353C probably damaging Het
Srcap T C 7: 127,559,892 probably benign Het
Sytl5 A G X: 9,905,595 H66R probably benign Het
Tlr7 T A X: 167,308,211 E93V probably damaging Het
Tmem156 A G 5: 65,079,984 L76S probably damaging Het
Tmem246 C T 4: 49,586,860 V103M possibly damaging Het
Tomm70a T C 16: 57,152,612 F571S probably damaging Het
Trmt10b A G 4: 45,314,347 Y261C possibly damaging Het
Other mutations in Gm17654
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01352:Gm17654 APN 14 43575874 missense probably damaging 1.00
IGL02611:Gm17654 APN 14 43579005 missense possibly damaging 0.58
IGL02750:Gm17654 APN 14 43578199 splice site probably benign
R5213:Gm17654 UTSW 14 43579102 missense probably damaging 0.98
R5504:Gm17654 UTSW 14 43578037 missense unknown
R6340:Gm17654 UTSW 14 43578077 missense unknown
R7054:Gm17654 UTSW 14 43575870 missense
Posted On2013-06-21