Incidental Mutation 'IGL01080:Phf11c'
ID52660
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Phf11c
Ensembl Gene ENSMUSG00000091144
Gene NamePHD finger protein 11C
SynonymsGm6907
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01080
Quality Score
Status
Chromosome14
Chromosomal Location59380833-59395381 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 59393199 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Isoleucine at position 19 (T19I)
Ref Sequence ENSEMBL: ENSMUSP00000131536 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000166912]
Predicted Effect probably benign
Transcript: ENSMUST00000166912
AA Change: T19I

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
SMART Domains Protein: ENSMUSP00000131536
Gene: ENSMUSG00000091144
AA Change: T19I

DomainStartEndE-ValueType
PHD 112 162 3.25e-4 SMART
low complexity region 178 186 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 25 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcb4 A T 5: 8,934,258 R663W probably damaging Het
Cacng5 A T 11: 107,877,928 F179L probably damaging Het
Cacng5 C T 11: 107,881,705 V106I probably benign Het
Cd96 T C 16: 46,049,693 E471G possibly damaging Het
Cpt1c T C 7: 44,960,909 D621G probably damaging Het
Csmd3 T C 15: 47,881,403 I1503V probably benign Het
Dmgdh T C 13: 93,703,778 probably benign Het
Flg A T 3: 93,279,599 K119N probably benign Het
Gale T C 4: 135,966,078 Y104H probably damaging Het
Gm8005 T C 14: 42,437,014 D119G unknown Het
Gstk1 A T 6: 42,246,626 D50V possibly damaging Het
Kmt2a T C 9: 44,809,092 D3866G unknown Het
Mastl A G 2: 23,146,148 S119P probably damaging Het
Olfr169 A T 16: 19,566,208 V225E probably damaging Het
Ppp1r16b A G 2: 158,757,172 T355A probably damaging Het
Prmt7 T G 8: 106,237,214 probably benign Het
Rad50 T C 11: 53,706,068 T44A probably damaging Het
Rangap1 C T 15: 81,705,752 probably benign Het
Slc27a3 A T 3: 90,385,460 V634E probably benign Het
Tbxas1 T A 6: 39,021,181 L228I probably damaging Het
Tnfaip3 T C 10: 19,011,655 K41E probably benign Het
Tti1 C T 2: 157,982,459 V1025I probably damaging Het
Tyrobp T C 7: 30,417,416 probably null Het
Wfdc16 A T 2: 164,638,486 W30R probably damaging Het
Zyg11b A T 4: 108,237,416 L657Q probably damaging Het
Other mutations in Phf11c
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01073:Phf11c APN 14 59389348 missense probably benign 0.07
IGL01819:Phf11c APN 14 59393137 missense probably benign 0.00
IGL02691:Phf11c APN 14 59384787 missense probably damaging 1.00
R0029:Phf11c UTSW 14 59384915 missense probably benign 0.02
R0965:Phf11c UTSW 14 59381482 missense probably damaging 1.00
R3001:Phf11c UTSW 14 59384840 missense probably damaging 1.00
R3002:Phf11c UTSW 14 59384840 missense probably damaging 1.00
R3081:Phf11c UTSW 14 59381484 missense probably benign
R4230:Phf11c UTSW 14 59393067 missense probably benign 0.00
R4432:Phf11c UTSW 14 59390935 missense possibly damaging 0.67
R5649:Phf11c UTSW 14 59385532 critical splice acceptor site probably null
Posted On2013-06-21