Incidental Mutation 'IGL01101:Gm8362'
ID52677
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm8362
Ensembl Gene ENSMUSG00000090404
Gene Namepredicted gene 8362
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01101
Quality Score
Status
Chromosome14
Chromosomal Location6765962-6774411 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 6767109 bp
ZygosityHeterozygous
Amino Acid Change Serine to Threonine at position 204 (S204T)
Ref Sequence ENSEMBL: ENSMUSP00000128839 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000168790] [ENSMUST00000170673]
Predicted Effect probably benign
Transcript: ENSMUST00000168790
AA Change: S204T

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
SMART Domains Protein: ENSMUSP00000128839
Gene: ENSMUSG00000090404
AA Change: S204T

DomainStartEndE-ValueType
Pfam:Takusan 48 128 8.3e-21 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000170673
SMART Domains Protein: ENSMUSP00000131018
Gene: ENSMUSG00000090404

DomainStartEndE-ValueType
Pfam:Takusan 46 129 4.9e-31 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000181787
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
5830411N06Rik A T 7: 140,296,104 Q543L probably benign Het
Adamts20 T A 15: 94,344,042 D695V probably damaging Het
Ahnak T C 19: 9,012,887 probably benign Het
Akap4 T A X: 7,076,184 M242K probably benign Het
Cd207 T C 6: 83,675,857 D97G probably benign Het
Cdc20 A G 4: 118,435,552 V333A possibly damaging Het
Cdhr2 A G 13: 54,718,135 probably benign Het
Cfhr1 T A 1: 139,553,584 Y186F probably benign Het
Cnbd1 T A 4: 18,907,098 I159F probably benign Het
Cyp2j11 A C 4: 96,339,095 M228R probably benign Het
Dach1 C A 14: 97,840,204 S581I possibly damaging Het
Dbnl A G 11: 5,793,722 D71G possibly damaging Het
F8 T A X: 75,287,387 T966S possibly damaging Het
Filip1 T A 9: 79,898,246 L75F probably benign Het
Foxi2 A G 7: 135,412,007 Y322C probably benign Het
Ftsj3 A G 11: 106,255,632 V7A probably benign Het
Ibtk C A 9: 85,732,622 probably benign Het
Marf1 C T 16: 14,146,736 V267I possibly damaging Het
Mmp27 T A 9: 7,573,415 D169E probably damaging Het
Olfr1115 C A 2: 87,252,462 T175K probably damaging Het
Olfr1247 C T 2: 89,609,847 C85Y probably benign Het
Olfr728 A T 14: 50,140,054 M195K probably benign Het
P4ha2 G T 11: 54,119,305 C296F probably damaging Het
Slc38a5 T C X: 8,271,511 probably benign Het
Sorbs2 G T 8: 45,745,423 R36L possibly damaging Het
Tmem207 A C 16: 26,517,877 Y42* probably null Het
Vmn2r115 G A 17: 23,345,997 R286K probably benign Het
Other mutations in Gm8362
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02118:Gm8362 APN 14 6771516 missense probably damaging 1.00
Posted On2013-06-21