Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01101:Gm8362'

52677

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm8362

Ensembl Gene

ENSMUSG00000090404

Gene Name

predicted gene 8362

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL01101

Quality Score

Status

Chromosome

Chromosomal Location

15695362-15703811 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 18145196 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Threonine at position 204 (S204T)

Ref Sequence

ENSEMBL: ENSMUSP00000128839 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000168790] [ENSMUST00000170673]

AlphaFold

K7N6Y6

Predicted Effect

probably benign
Transcript: ENSMUST00000168790
AA Change: S204T

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)

SMART Domains

Protein: ENSMUSP00000128839
Gene: ENSMUSG00000090404
AA Change: S204T

Domain	Start	End	E-Value	Type
Pfam:Takusan	48	128	8.3e-21	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000170673

SMART Domains

Protein: ENSMUSP00000131018
Gene: ENSMUSG00000090404

Domain	Start	End	E-Value	Type
Pfam:Takusan	46	129	4.9e-31	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000181787

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 27 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adamts20	T	A	15: 94,241,923 (GRCm39)	D695V	probably damaging	Het
Ahnak	T	C	19: 8,990,251 (GRCm39)		probably benign	Het
Akap4	T	A	X: 6,942,423 (GRCm39)	M242K	probably benign	Het
Cd207	T	C	6: 83,652,839 (GRCm39)	D97G	probably benign	Het
Cdc20	A	G	4: 118,292,749 (GRCm39)	V333A	possibly damaging	Het
Cdhr2	A	G	13: 54,865,948 (GRCm39)		probably benign	Het
Cfhr1	T	A	1: 139,481,322 (GRCm39)	Y186F	probably benign	Het
Cnbd1	T	A	4: 18,907,098 (GRCm39)	I159F	probably benign	Het
Cyp2j11	A	C	4: 96,227,332 (GRCm39)	M228R	probably benign	Het
Dach1	C	A	14: 98,077,640 (GRCm39)	S581I	possibly damaging	Het
Dbnl	A	G	11: 5,743,722 (GRCm39)	D71G	possibly damaging	Het
F8	T	A	X: 74,330,993 (GRCm39)	T966S	possibly damaging	Het
Filip1	T	A	9: 79,805,528 (GRCm39)	L75F	probably benign	Het
Foxi2	A	G	7: 135,013,736 (GRCm39)	Y322C	probably benign	Het
Ftsj3	A	G	11: 106,146,458 (GRCm39)	V7A	probably benign	Het
Ibtk	C	A	9: 85,614,675 (GRCm39)		probably benign	Het
Marf1	C	T	16: 13,964,600 (GRCm39)	V267I	possibly damaging	Het
Mmp27	T	A	9: 7,573,416 (GRCm39)	D169E	probably damaging	Het
Or10ag53	C	A	2: 87,082,806 (GRCm39)	T175K	probably damaging	Het
Or4a74	C	T	2: 89,440,191 (GRCm39)	C85Y	probably benign	Het
Or4k1	A	T	14: 50,377,511 (GRCm39)	M195K	probably benign	Het
P4ha2	G	T	11: 54,010,131 (GRCm39)	C296F	probably damaging	Het
Scart2	A	T	7: 139,876,017 (GRCm39)	Q543L	probably benign	Het
Slc38a5	T	C	X: 8,137,750 (GRCm39)		probably benign	Het
Sorbs2	G	T	8: 46,198,460 (GRCm39)	R36L	possibly damaging	Het
Tmem207	A	C	16: 26,336,627 (GRCm39)	Y42*	probably null	Het
Vmn2r115	G	A	17: 23,564,971 (GRCm39)	R286K	probably benign	Het

Other mutations in Gm8362

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02118:Gm8362	APN	14	18,149,595 (GRCm39)	missense	probably damaging	1.00
R8947:Gm8362	UTSW	14	18,151,405 (GRCm39)	critical splice donor site	probably null

Posted On

2013-06-21