Incidental Mutation 'IGL01101:Tmem207'
ID52920
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tmem207
Ensembl Gene ENSMUSG00000091972
Gene Nametransmembrane protein 207
SynonymsLOC224058, 100043057
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.055) question?
Stock #IGL01101
Quality Score
Status
Chromosome16
Chromosomal Location26503656-26526769 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) A to C at 26517877 bp
ZygosityHeterozygous
Amino Acid Change Tyrosine to Stop codon at position 42 (Y42*)
Ref Sequence ENSEMBL: ENSMUSP00000127563 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000165687]
Predicted Effect probably null
Transcript: ENSMUST00000165687
AA Change: Y42*
SMART Domains Protein: ENSMUSP00000127563
Gene: ENSMUSG00000091972
AA Change: Y42*

DomainStartEndE-ValueType
Pfam:TMEM52 31 92 4.2e-10 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000231658
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
5830411N06Rik A T 7: 140,296,104 Q543L probably benign Het
Adamts20 T A 15: 94,344,042 D695V probably damaging Het
Ahnak T C 19: 9,012,887 probably benign Het
Akap4 T A X: 7,076,184 M242K probably benign Het
Cd207 T C 6: 83,675,857 D97G probably benign Het
Cdc20 A G 4: 118,435,552 V333A possibly damaging Het
Cdhr2 A G 13: 54,718,135 probably benign Het
Cfhr1 T A 1: 139,553,584 Y186F probably benign Het
Cnbd1 T A 4: 18,907,098 I159F probably benign Het
Cyp2j11 A C 4: 96,339,095 M228R probably benign Het
Dach1 C A 14: 97,840,204 S581I possibly damaging Het
Dbnl A G 11: 5,793,722 D71G possibly damaging Het
F8 T A X: 75,287,387 T966S possibly damaging Het
Filip1 T A 9: 79,898,246 L75F probably benign Het
Foxi2 A G 7: 135,412,007 Y322C probably benign Het
Ftsj3 A G 11: 106,255,632 V7A probably benign Het
Gm8362 A T 14: 6,767,109 S204T probably benign Het
Ibtk C A 9: 85,732,622 probably benign Het
Marf1 C T 16: 14,146,736 V267I possibly damaging Het
Mmp27 T A 9: 7,573,415 D169E probably damaging Het
Olfr1115 C A 2: 87,252,462 T175K probably damaging Het
Olfr1247 C T 2: 89,609,847 C85Y probably benign Het
Olfr728 A T 14: 50,140,054 M195K probably benign Het
P4ha2 G T 11: 54,119,305 C296F probably damaging Het
Slc38a5 T C X: 8,271,511 probably benign Het
Sorbs2 G T 8: 45,745,423 R36L possibly damaging Het
Vmn2r115 G A 17: 23,345,997 R286K probably benign Het
Other mutations in Tmem207
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02140:Tmem207 APN 16 26516740 missense probably benign 0.01
IGL02249:Tmem207 APN 16 26517867 missense possibly damaging 0.86
IGL02394:Tmem207 APN 16 26516836 splice site probably benign
IGL03380:Tmem207 APN 16 26526657 missense probably damaging 1.00
R0058:Tmem207 UTSW 16 26524829 splice site probably benign
R0058:Tmem207 UTSW 16 26524829 splice site probably benign
R1839:Tmem207 UTSW 16 26524821 missense possibly damaging 0.80
R4943:Tmem207 UTSW 16 26517853 nonsense probably null
R7348:Tmem207 UTSW 16 26516827 missense possibly damaging 0.68
Posted On2013-06-21