Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01101:Tmem207'

52920

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tmem207

Ensembl Gene

ENSMUSG00000091972

Gene Name

transmembrane protein 207

Synonyms

LOC224058, 100043057

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.053) question?

Stock #

IGL01101

Quality Score

Status

Chromosome

Chromosomal Location

26503656-26526769 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

A to C at 26517877 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Stop codon at position 42 (Y42*)

Ref Sequence

ENSEMBL: ENSMUSP00000127563 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000165687]

AlphaFold

P86045

Predicted Effect

probably null
Transcript: ENSMUST00000165687
AA Change: Y42*

SMART Domains

Protein: ENSMUSP00000127563
Gene: ENSMUSG00000091972
AA Change: Y42*

Domain	Start	End	E-Value	Type
Pfam:TMEM52	31	92	4.2e-10	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000231658

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 27 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
5830411N06Rik	A	T	7: 140,296,104	Q543L	probably benign	Het
Adamts20	T	A	15: 94,344,042	D695V	probably damaging	Het
Ahnak	T	C	19: 9,012,887		probably benign	Het
Akap4	T	A	X: 7,076,184	M242K	probably benign	Het
Cd207	T	C	6: 83,675,857	D97G	probably benign	Het
Cdc20	A	G	4: 118,435,552	V333A	possibly damaging	Het
Cdhr2	A	G	13: 54,718,135		probably benign	Het
Cfhr1	T	A	1: 139,553,584	Y186F	probably benign	Het
Cnbd1	T	A	4: 18,907,098	I159F	probably benign	Het
Cyp2j11	A	C	4: 96,339,095	M228R	probably benign	Het
Dach1	C	A	14: 97,840,204	S581I	possibly damaging	Het
Dbnl	A	G	11: 5,793,722	D71G	possibly damaging	Het
F8	T	A	X: 75,287,387	T966S	possibly damaging	Het
Filip1	T	A	9: 79,898,246	L75F	probably benign	Het
Foxi2	A	G	7: 135,412,007	Y322C	probably benign	Het
Ftsj3	A	G	11: 106,255,632	V7A	probably benign	Het
Gm8362	A	T	14: 6,767,109	S204T	probably benign	Het
Ibtk	C	A	9: 85,732,622		probably benign	Het
Marf1	C	T	16: 14,146,736	V267I	possibly damaging	Het
Mmp27	T	A	9: 7,573,415	D169E	probably damaging	Het
Olfr1115	C	A	2: 87,252,462	T175K	probably damaging	Het
Olfr1247	C	T	2: 89,609,847	C85Y	probably benign	Het
Olfr728	A	T	14: 50,140,054	M195K	probably benign	Het
P4ha2	G	T	11: 54,119,305	C296F	probably damaging	Het
Slc38a5	T	C	X: 8,271,511		probably benign	Het
Sorbs2	G	T	8: 45,745,423	R36L	possibly damaging	Het
Vmn2r115	G	A	17: 23,345,997	R286K	probably benign	Het

Other mutations in Tmem207

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02140:Tmem207	APN	16	26516740	missense	probably benign	0.01
IGL02249:Tmem207	APN	16	26517867	missense	possibly damaging	0.86
IGL02394:Tmem207	APN	16	26516836	splice site	probably benign
IGL03380:Tmem207	APN	16	26526657	missense	probably damaging	1.00
R0058:Tmem207	UTSW	16	26524829	splice site	probably benign
R0058:Tmem207	UTSW	16	26524829	splice site	probably benign
R1839:Tmem207	UTSW	16	26524821	missense	possibly damaging	0.80
R4943:Tmem207	UTSW	16	26517853	nonsense	probably null
R7348:Tmem207	UTSW	16	26516827	missense	possibly damaging	0.68
R7947:Tmem207	UTSW	16	26516745	missense	possibly damaging	0.82
R9358:Tmem207	UTSW	16	26526684	missense	probably benign	0.07
R9464:Tmem207	UTSW	16	26526663	missense
R9564:Tmem207	UTSW	16	26516749	nonsense	probably null

Posted On

2013-06-21