Incidental Mutation 'IGL01067:Fpr3'
ID53005
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Fpr3
Ensembl Gene ENSMUSG00000079700
Gene Nameformyl peptide receptor 3
SynonymsLXA4-R, Fpr-rs1, Lxa4r, Fprl1
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01067
Quality Score
Status
Chromosome17
Chromosomal Location17887852-17971677 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 17970566 bp
ZygosityHeterozygous
Amino Acid Change Valine to Aspartic acid at position 33 (V33D)
Ref Sequence ENSEMBL: ENSMUSP00000111227 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000054871] [ENSMUST00000115565]
Predicted Effect probably benign
Transcript: ENSMUST00000054871
AA Change: V33D

PolyPhen 2 Score 0.166 (Sensitivity: 0.92; Specificity: 0.87)
SMART Domains Protein: ENSMUSP00000093316
Gene: ENSMUSG00000079700
AA Change: V33D

DomainStartEndE-ValueType
Pfam:7tm_1 43 302 2.2e-43 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000115565
AA Change: V33D

PolyPhen 2 Score 0.166 (Sensitivity: 0.92; Specificity: 0.87)
SMART Domains Protein: ENSMUSP00000111227
Gene: ENSMUSG00000079700
AA Change: V33D

DomainStartEndE-ValueType
Pfam:7tm_1 43 302 1.5e-36 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 50 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1110038F14Rik G A 15: 76,950,275 V124I probably damaging Het
A330008L17Rik T C 8: 99,421,954 noncoding transcript Het
Acp4 C T 7: 44,253,452 V331I probably benign Het
Aen G A 7: 78,907,302 M299I probably damaging Het
Alg6 T C 4: 99,741,570 V128A probably benign Het
Ank3 A G 10: 69,850,196 K280E probably damaging Het
Bfar T C 16: 13,685,241 C36R probably damaging Het
Car14 A G 3: 95,898,816 I311T probably damaging Het
Cd300c T C 11: 114,960,427 probably benign Het
Cfap100 T A 6: 90,406,114 E513V probably damaging Het
Clip1 C A 5: 123,630,804 K612N probably damaging Het
Depdc5 A G 5: 32,899,067 probably null Het
Dock3 A T 9: 107,082,373 probably null Het
Dph6 A T 2: 114,647,809 M17K probably damaging Het
Enkur T C 2: 21,189,231 Q177R probably benign Het
Faap100 T C 11: 120,372,132 H800R probably damaging Het
Fastkd2 T G 1: 63,737,771 probably benign Het
Fcgr2b A T 1: 170,968,053 N102K possibly damaging Het
Fezf1 C T 6: 23,247,843 V78I possibly damaging Het
Fmn2 A T 1: 174,503,319 D425V unknown Het
Fnta G A 8: 26,007,201 Q207* probably null Het
Fshr C T 17: 88,985,393 C619Y possibly damaging Het
Gbp3 T C 3: 142,566,597 probably null Het
Gjb2 A G 14: 57,100,172 V193A possibly damaging Het
Il4ra A G 7: 125,575,161 T292A probably benign Het
Lama5 A G 2: 180,176,543 probably benign Het
Marveld3 G T 8: 109,961,964 D48E possibly damaging Het
Meox1 A T 11: 101,893,773 I78N probably benign Het
Ncor1 A T 11: 62,392,528 H444Q probably damaging Het
Ndst3 T C 3: 123,546,817 Q784R probably damaging Het
Olfr1123 A G 2: 87,418,370 I107M probably benign Het
Olfr1294 T A 2: 111,538,014 I92F probably damaging Het
Pld5 A T 1: 176,274,879 probably benign Het
Plk1 G A 7: 122,168,925 R456H probably damaging Het
Polr2a T A 11: 69,748,014 I65F possibly damaging Het
Ptprd T A 4: 76,059,685 I196F probably damaging Het
Qsox2 T C 2: 26,228,396 N121S probably damaging Het
Reln A G 5: 21,979,666 L1617S probably damaging Het
Rragc T C 4: 123,929,968 F345L probably benign Het
Sass6 A T 3: 116,613,956 E240D possibly damaging Het
Shcbp1l A C 1: 153,436,024 S308R possibly damaging Het
Slc1a5 T A 7: 16,786,879 C224* probably null Het
Slc27a5 T C 7: 12,989,072 E567G probably damaging Het
Synj2 T A 17: 6,037,926 N1417K possibly damaging Het
Tbc1d9 A G 8: 83,234,162 T214A probably damaging Het
Tjp3 C A 10: 81,273,865 V835L probably benign Het
Trpc4 C A 3: 54,222,562 Q250K probably benign Het
Ttn A T 2: 76,745,162 I25129N probably damaging Het
Ube4a T A 9: 44,944,865 Y523F probably damaging Het
Zfp971 G A 2: 178,023,382 probably null Het
Other mutations in Fpr3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01520:Fpr3 APN 17 17971063 missense possibly damaging 0.69
IGL02166:Fpr3 APN 17 17970464 utr 5 prime probably benign
IGL02380:Fpr3 APN 17 17970992 missense probably benign 0.00
IGL02587:Fpr3 APN 17 17970691 missense probably benign 0.12
R1521:Fpr3 UTSW 17 17971015 missense probably damaging 1.00
R1533:Fpr3 UTSW 17 17970660 nonsense probably null
R1913:Fpr3 UTSW 17 17971408 missense probably damaging 0.96
R2099:Fpr3 UTSW 17 17971181 missense probably damaging 1.00
R2140:Fpr3 UTSW 17 17970617 missense probably damaging 1.00
R2206:Fpr3 UTSW 17 17970646 missense probably damaging 1.00
R2219:Fpr3 UTSW 17 17971382 missense possibly damaging 0.93
R2224:Fpr3 UTSW 17 17971193 missense probably damaging 1.00
R2244:Fpr3 UTSW 17 17971187 missense probably benign 0.03
R2994:Fpr3 UTSW 17 17970868 nonsense probably null
R5364:Fpr3 UTSW 17 17970544 missense probably benign 0.00
R6179:Fpr3 UTSW 17 17970657 nonsense probably null
R6781:Fpr3 UTSW 17 17970716 missense probably benign 0.09
R6909:Fpr3 UTSW 17 17971167 missense probably benign 0.00
R7565:Fpr3 UTSW 17 17970965 missense probably damaging 1.00
R8008:Fpr3 UTSW 17 17971453 missense probably benign 0.03
X0021:Fpr3 UTSW 17 17971238 missense probably benign 0.06
Z1176:Fpr3 UTSW 17 17970993 missense possibly damaging 0.55
Posted On2013-06-21