Mutagenetix > Incidental Mutation

Incidental Mutation 'R6750:Pkd1l1'

530720

Institutional Source

Beutler Lab

Gene Symbol

Pkd1l1

Ensembl Gene

ENSMUSG00000046634

Gene Name

polycystic kidney disease 1 like 1

Synonyms

MMRRC Submission

044867-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R6750 (G1)

Quality Score

195.009

Status

Validated

Chromosome

Chromosomal Location

8782025-8924365 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 8923217 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Threonine at position 17 (S17T)

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000154153
AA Change: S17T

SMART Domains

Protein: ENSMUSP00000120803
Gene: ENSMUSG00000046634
AA Change: S17T

Domain	Start	End	E-Value	Type
low complexity region	172	184	N/A	INTRINSIC
PKD	205	287	2.9e0	SMART
PKD	291	369	1.42e-9	SMART
Pfam:REJ	398	1001	1.7e-45	PFAM
low complexity region	1208	1218	N/A	INTRINSIC
GPS	1370	1413	1.21e-1	SMART
transmembrane domain	1434	1451	N/A	INTRINSIC
LH2	1479	1598	2.94e-3	SMART
transmembrane domain	1640	1659	N/A	INTRINSIC
transmembrane domain	1679	1701	N/A	INTRINSIC
transmembrane domain	1817	1839	N/A	INTRINSIC
transmembrane domain	1854	1876	N/A	INTRINSIC
Pfam:PKD_channel	2109	2339	1.5e-23	PFAM
transmembrane domain	2381	2403	N/A	INTRINSIC
low complexity region	2436	2449	N/A	INTRINSIC
low complexity region	2458	2469	N/A	INTRINSIC

Meta Mutation Damage Score

0.0684

Coding Region Coverage

1x: 99.9%
3x: 99.5%
10x: 97.6%
20x: 92.7%

Validation Efficiency

100% (75/75)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the polycystin protein family containing 11 transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for an ENU induced point mutation display lethality throughout fetal growth and development with abnormalities in left right patterning and heterotaxia. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 73 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adal	A	T	2: 120,973,130 (GRCm39)	L62F	probably damaging	Het
Akap13	C	T	7: 75,389,206 (GRCm39)	P2375S	probably benign	Het
Apob	T	A	12: 8,047,853 (GRCm39)	L931Q	probably damaging	Het
Arcn1	A	G	9: 44,661,691 (GRCm39)	V391A	possibly damaging	Het
Ccdc162	A	T	10: 41,437,222 (GRCm39)	I1729N	possibly damaging	Het
Cd24a	T	C	10: 43,458,721 (GRCm39)	L86P	unknown	Het
Cdcp3	T	A	7: 130,889,974 (GRCm39)		probably benign	Het
Churc1	C	A	12: 76,822,405 (GRCm39)	H71Q	probably damaging	Het
Clcn3	A	G	8: 61,367,809 (GRCm39)	L780P	possibly damaging	Het
Cldn17	C	T	16: 88,303,195 (GRCm39)	G178E	possibly damaging	Het
Cmah	A	G	13: 24,648,235 (GRCm39)	Y345C	probably damaging	Het
Cntnap5b	C	T	1: 100,202,224 (GRCm39)	S357L	probably damaging	Het
Col6a6	A	G	9: 105,660,879 (GRCm39)	I410T	probably damaging	Het
Crmp1	T	C	5: 37,422,666 (GRCm39)		probably null	Het
Csmd2	A	C	4: 128,091,018 (GRCm39)	N186H	possibly damaging	Het
Cyp1a1	A	T	9: 57,607,539 (GRCm39)	M56L	probably benign	Het
D2hgdh	G	C	1: 93,754,129 (GRCm39)	R56P	probably benign	Het
Dapk2	A	G	9: 66,128,034 (GRCm39)	E104G	probably damaging	Het
Dld	T	C	12: 31,382,213 (GRCm39)	N498S	probably benign	Het
Dyrk4	G	T	6: 126,875,918 (GRCm39)	Q106K	probably benign	Het
Eif2b4	T	C	5: 31,347,304 (GRCm39)	I333V	probably damaging	Het
F5	A	G	1: 164,021,076 (GRCm39)	T1184A	possibly damaging	Het
Fbxl6	C	T	15: 76,422,612 (GRCm39)	G102D	probably damaging	Het
Foxa1	C	T	12: 57,589,396 (GRCm39)	G275R	probably benign	Het
Fryl	A	G	5: 73,179,575 (GRCm39)	I2944T	probably damaging	Het
Gna15	T	C	10: 81,350,117 (GRCm39)	D95G	probably benign	Het
Greb1	T	A	12: 16,738,584 (GRCm39)	M1460L	probably benign	Het
Herc1	TCCC	TCC	9: 66,408,470 (GRCm39)		probably null	Het
Herc2	T	C	7: 55,747,195 (GRCm39)	I444T	probably damaging	Het
Ifngr1	T	A	10: 19,485,099 (GRCm39)	M366K	probably benign	Het
Krt27	C	T	11: 99,239,806 (GRCm39)	E253K	probably damaging	Het
Mical2	C	T	7: 111,981,046 (GRCm39)	T406I	probably damaging	Het
Mocs2	T	G	13: 114,962,784 (GRCm39)	D156E	probably damaging	Het
Mprip	A	T	11: 59,586,957 (GRCm39)	K43N	probably damaging	Het
Myo5b	A	T	18: 74,750,106 (GRCm39)	T190S	possibly damaging	Het
Naa25	C	T	5: 121,546,372 (GRCm39)	T86M	probably damaging	Het
Ncam1	T	C	9: 49,478,639 (GRCm39)	D163G	probably damaging	Het
Nlrp4f	A	T	13: 65,329,468 (GRCm39)	Y908*	probably null	Het
Nlrp9b	T	A	7: 19,757,159 (GRCm39)	L132*	probably null	Het
Nrg1	A	C	8: 32,308,124 (GRCm39)	S679A	probably damaging	Het
Or1j1	C	A	2: 36,702,954 (GRCm39)	R50M	possibly damaging	Het
Or52p1	C	T	7: 104,267,320 (GRCm39)	R145C	probably damaging	Het
Paqr9	A	T	9: 95,443,050 (GRCm39)	T347S	probably damaging	Het
Pcdhb21	T	C	18: 37,647,501 (GRCm39)	L210P	probably damaging	Het
Pdzd7	T	G	19: 45,016,187 (GRCm39)	D978A	probably benign	Het
Phf8-ps	A	T	17: 33,285,372 (GRCm39)	S477T	possibly damaging	Het
Plcz1	T	C	6: 139,974,164 (GRCm39)	K93E	possibly damaging	Het
Pom121l2	G	C	13: 22,166,107 (GRCm39)	R126P	probably damaging	Het
Prkg1	C	T	19: 31,741,961 (GRCm39)	E88K	probably benign	Het
Psme4	A	T	11: 30,803,203 (GRCm39)	D15V	probably damaging	Het
Ptprf	A	G	4: 118,088,928 (GRCm39)	V625A	probably benign	Het
Rab27a	G	A	9: 72,992,290 (GRCm39)	S106N	probably damaging	Het
Rasa4	A	G	5: 136,129,802 (GRCm39)	T261A	probably benign	Het
Sardh	T	C	2: 27,118,269 (GRCm39)	D487G	probably benign	Het
Sec16a	A	G	2: 26,330,030 (GRCm39)	Y662H	probably benign	Het
Sema3d	T	A	5: 12,635,067 (GRCm39)	L711*	probably null	Het
Septin14	T	A	5: 129,773,181 (GRCm39)	Y152F	probably damaging	Het
Smc5	A	G	19: 23,220,004 (GRCm39)	L411P	probably damaging	Het
Spata31e5	C	A	1: 28,816,495 (GRCm39)	E512D	probably damaging	Het
Spg7	T	A	8: 123,800,650 (GRCm39)	V39E	probably damaging	Het
Tas2r117	A	G	6: 132,779,817 (GRCm39)		probably benign	Het
Tle1	A	T	4: 72,040,687 (GRCm39)	I631N	probably damaging	Het
Tmed3	T	A	9: 89,581,843 (GRCm39)	S207C	probably damaging	Het
Tmem59l	G	A	8: 70,939,022 (GRCm39)	P51S	probably benign	Het
Trpc3	A	G	3: 36,678,542 (GRCm39)	Y848H	probably damaging	Het
Tsen2	T	C	6: 115,526,881 (GRCm39)	F66S	probably damaging	Het
Ttll5	T	A	12: 86,003,384 (GRCm39)	S216R	probably damaging	Het
Usp22	A	T	11: 61,048,042 (GRCm39)	V426E	probably damaging	Het
Vmn2r76	T	C	7: 85,875,114 (GRCm39)	N621S	probably damaging	Het
Wdr75	A	G	1: 45,856,539 (GRCm39)	T521A	probably damaging	Het
Wrnip1	T	A	13: 32,986,739 (GRCm39)	D173E	probably damaging	Het
Zfp317	G	A	9: 19,559,100 (GRCm39)	G438D	probably damaging	Het
Zscan10	T	A	17: 23,826,164 (GRCm39)	S109T	possibly damaging	Het

Other mutations in Pkd1l1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00093:Pkd1l1	APN	11	8,911,971 (GRCm39)	missense	unknown
IGL00156:Pkd1l1	APN	11	8,900,515 (GRCm39)	missense	probably damaging	1.00
IGL00161:Pkd1l1	APN	11	8,879,353 (GRCm39)	critical splice donor site	probably null
IGL00489:Pkd1l1	APN	11	8,784,773 (GRCm39)	critical splice donor site	probably null
IGL00495:Pkd1l1	APN	11	8,818,493 (GRCm39)	missense	probably benign	0.34
IGL00983:Pkd1l1	APN	11	8,794,585 (GRCm39)	missense	probably benign
IGL01071:Pkd1l1	APN	11	8,798,921 (GRCm39)	missense	probably benign	0.00
IGL01093:Pkd1l1	APN	11	8,851,345 (GRCm39)	missense	probably benign	0.06
IGL01295:Pkd1l1	APN	11	8,883,685 (GRCm39)	missense	possibly damaging	0.93
IGL01311:Pkd1l1	APN	11	8,851,174 (GRCm39)	missense	possibly damaging	0.53
IGL01412:Pkd1l1	APN	11	8,900,409 (GRCm39)	missense	possibly damaging	0.73
IGL01978:Pkd1l1	APN	11	8,911,336 (GRCm39)	missense	unknown
IGL01999:Pkd1l1	APN	11	8,786,291 (GRCm39)	missense	probably benign
IGL02080:Pkd1l1	APN	11	8,911,345 (GRCm39)	missense	unknown
IGL02106:Pkd1l1	APN	11	8,783,800 (GRCm39)	missense	probably damaging	1.00
IGL02216:Pkd1l1	APN	11	8,784,897 (GRCm39)	missense	probably damaging	0.96
IGL02305:Pkd1l1	APN	11	8,852,467 (GRCm39)	missense	probably benign
IGL02337:Pkd1l1	APN	11	8,892,079 (GRCm39)	missense	probably damaging	1.00
IGL02576:Pkd1l1	APN	11	8,794,560 (GRCm39)	missense	possibly damaging	0.61
IGL02704:Pkd1l1	APN	11	8,784,910 (GRCm39)	missense	probably benign	0.00
IGL02814:Pkd1l1	APN	11	8,852,582 (GRCm39)	missense	probably benign	0.01
IGL02904:Pkd1l1	APN	11	8,818,450 (GRCm39)	splice site	probably benign
IGL02972:Pkd1l1	APN	11	8,813,908 (GRCm39)	missense	probably damaging	0.99
IGL03091:Pkd1l1	APN	11	8,805,564 (GRCm39)	missense	probably damaging	1.00
IGL03113:Pkd1l1	APN	11	8,784,793 (GRCm39)	missense	probably benign	0.20
IGL03210:Pkd1l1	APN	11	8,915,127 (GRCm39)	missense	unknown
PIT4581001:Pkd1l1	UTSW	11	8,866,298 (GRCm39)	frame shift	probably null
R0020:Pkd1l1	UTSW	11	8,825,765 (GRCm39)	splice site	probably benign
R0020:Pkd1l1	UTSW	11	8,825,765 (GRCm39)	splice site	probably benign
R0496:Pkd1l1	UTSW	11	8,879,430 (GRCm39)	missense	probably damaging	0.96
R0547:Pkd1l1	UTSW	11	8,786,448 (GRCm39)	splice site	probably benign
R0582:Pkd1l1	UTSW	11	8,881,699 (GRCm39)	splice site	probably benign
R0761:Pkd1l1	UTSW	11	8,804,375 (GRCm39)	missense	probably damaging	1.00
R0969:Pkd1l1	UTSW	11	8,886,898 (GRCm39)	missense	probably damaging	1.00
R1348:Pkd1l1	UTSW	11	8,784,806 (GRCm39)	missense	probably benign	0.18
R1366:Pkd1l1	UTSW	11	8,891,038 (GRCm39)	splice site	probably benign
R1401:Pkd1l1	UTSW	11	8,804,487 (GRCm39)	nonsense	probably null
R1444:Pkd1l1	UTSW	11	8,804,386 (GRCm39)	missense	probably damaging	1.00
R1445:Pkd1l1	UTSW	11	8,820,313 (GRCm39)	missense	probably benign	0.00
R1463:Pkd1l1	UTSW	11	8,866,302 (GRCm39)	missense	probably damaging	1.00
R1496:Pkd1l1	UTSW	11	8,891,077 (GRCm39)	missense	possibly damaging	0.95
R1542:Pkd1l1	UTSW	11	8,824,179 (GRCm39)	missense	possibly damaging	0.82
R1543:Pkd1l1	UTSW	11	8,851,200 (GRCm39)	missense	probably damaging	1.00
R1619:Pkd1l1	UTSW	11	8,900,413 (GRCm39)	missense	probably damaging	0.98
R1875:Pkd1l1	UTSW	11	8,794,670 (GRCm39)	splice site	probably benign
R1929:Pkd1l1	UTSW	11	8,786,197 (GRCm39)	splice site	probably benign
R1958:Pkd1l1	UTSW	11	8,824,161 (GRCm39)	missense	probably benign	0.01
R2223:Pkd1l1	UTSW	11	8,900,422 (GRCm39)	missense	probably benign
R2223:Pkd1l1	UTSW	11	8,839,063 (GRCm39)	missense	probably benign	0.18
R2264:Pkd1l1	UTSW	11	8,829,112 (GRCm39)	missense	probably damaging	0.97
R2349:Pkd1l1	UTSW	11	8,776,819 (GRCm39)	splice site	probably null
R2431:Pkd1l1	UTSW	11	8,897,197 (GRCm39)	missense	probably damaging	0.99
R2483:Pkd1l1	UTSW	11	8,912,701 (GRCm39)	missense	probably damaging	1.00
R2517:Pkd1l1	UTSW	11	8,908,900 (GRCm39)	missense	unknown
R2888:Pkd1l1	UTSW	11	8,897,251 (GRCm39)	missense	probably damaging	1.00
R2965:Pkd1l1	UTSW	11	8,824,236 (GRCm39)	missense	probably damaging	1.00
R3123:Pkd1l1	UTSW	11	8,923,021 (GRCm39)	missense	unknown
R3153:Pkd1l1	UTSW	11	8,817,207 (GRCm39)	missense	probably benign	0.01
R3840:Pkd1l1	UTSW	11	8,839,050 (GRCm39)	missense	probably damaging	1.00
R3855:Pkd1l1	UTSW	11	8,915,047 (GRCm39)	critical splice donor site	probably null
R3880:Pkd1l1	UTSW	11	8,911,983 (GRCm39)	missense	unknown
R3970:Pkd1l1	UTSW	11	8,824,218 (GRCm39)	missense	probably damaging	1.00
R4195:Pkd1l1	UTSW	11	8,859,929 (GRCm39)	missense	probably damaging	1.00
R4196:Pkd1l1	UTSW	11	8,859,929 (GRCm39)	missense	probably damaging	1.00
R4246:Pkd1l1	UTSW	11	8,815,543 (GRCm39)	missense	possibly damaging	0.51
R4247:Pkd1l1	UTSW	11	8,815,543 (GRCm39)	missense	possibly damaging	0.51
R4249:Pkd1l1	UTSW	11	8,815,543 (GRCm39)	missense	possibly damaging	0.51
R4250:Pkd1l1	UTSW	11	8,815,543 (GRCm39)	missense	possibly damaging	0.51
R4593:Pkd1l1	UTSW	11	8,851,253 (GRCm39)	missense	probably damaging	0.97
R4609:Pkd1l1	UTSW	11	8,908,964 (GRCm39)	missense	unknown
R4797:Pkd1l1	UTSW	11	8,911,340 (GRCm39)	missense	unknown
R4910:Pkd1l1	UTSW	11	8,879,360 (GRCm39)	missense	possibly damaging	0.50
R4940:Pkd1l1	UTSW	11	8,794,585 (GRCm39)	missense	probably benign
R5084:Pkd1l1	UTSW	11	8,892,004 (GRCm39)	missense	probably benign	0.05
R5147:Pkd1l1	UTSW	11	8,799,003 (GRCm39)	missense	possibly damaging	0.71
R5360:Pkd1l1	UTSW	11	8,829,204 (GRCm39)	missense	probably benign
R5483:Pkd1l1	UTSW	11	8,851,141 (GRCm39)	critical splice donor site	probably null
R5604:Pkd1l1	UTSW	11	8,783,877 (GRCm39)	missense	probably damaging	0.98
R5642:Pkd1l1	UTSW	11	8,829,202 (GRCm39)	missense	probably damaging	1.00
R5652:Pkd1l1	UTSW	11	8,859,889 (GRCm39)	missense	probably benign	0.03
R5751:Pkd1l1	UTSW	11	8,817,204 (GRCm39)	missense	possibly damaging	0.45
R5761:Pkd1l1	UTSW	11	8,866,301 (GRCm39)	missense	probably damaging	1.00
R5800:Pkd1l1	UTSW	11	8,811,302 (GRCm39)	missense	probably benign
R5874:Pkd1l1	UTSW	11	8,858,688 (GRCm39)	missense	probably damaging	1.00
R5897:Pkd1l1	UTSW	11	8,829,176 (GRCm39)	missense	probably benign	0.03
R5913:Pkd1l1	UTSW	11	8,813,849 (GRCm39)	missense	probably benign	0.00
R5930:Pkd1l1	UTSW	11	8,908,969 (GRCm39)	missense	unknown
R6000:Pkd1l1	UTSW	11	8,900,427 (GRCm39)	missense	probably benign	0.00
R6005:Pkd1l1	UTSW	11	8,807,113 (GRCm39)	missense	probably damaging	1.00
R6013:Pkd1l1	UTSW	11	8,819,452 (GRCm39)	splice site	probably null
R6027:Pkd1l1	UTSW	11	8,866,272 (GRCm39)	nonsense	probably null
R6028:Pkd1l1	UTSW	11	8,786,267 (GRCm39)	missense	probably benign	0.06
R6129:Pkd1l1	UTSW	11	8,818,543 (GRCm39)	missense	probably benign	0.00
R6182:Pkd1l1	UTSW	11	8,815,555 (GRCm39)	missense	probably benign	0.36
R6226:Pkd1l1	UTSW	11	8,851,287 (GRCm39)	missense	probably benign	0.00
R6257:Pkd1l1	UTSW	11	8,892,195 (GRCm39)	missense	probably benign	0.22
R6340:Pkd1l1	UTSW	11	8,794,649 (GRCm39)	missense	probably benign	0.09
R6478:Pkd1l1	UTSW	11	8,813,911 (GRCm39)	missense	probably benign	0.00
R6558:Pkd1l1	UTSW	11	8,839,052 (GRCm39)	missense	probably benign	0.00
R6987:Pkd1l1	UTSW	11	8,852,575 (GRCm39)	missense	probably benign	0.01
R6996:Pkd1l1	UTSW	11	8,799,046 (GRCm39)	missense	probably damaging	1.00
R7139:Pkd1l1	UTSW	11	8,840,737 (GRCm39)	missense
R7224:Pkd1l1	UTSW	11	8,895,241 (GRCm39)	missense
R7244:Pkd1l1	UTSW	11	8,821,771 (GRCm39)	missense
R7265:Pkd1l1	UTSW	11	8,879,402 (GRCm39)	missense
R7358:Pkd1l1	UTSW	11	8,895,202 (GRCm39)	missense
R7387:Pkd1l1	UTSW	11	8,851,203 (GRCm39)	missense
R7414:Pkd1l1	UTSW	11	8,866,267 (GRCm39)	missense
R7459:Pkd1l1	UTSW	11	8,852,428 (GRCm39)	missense
R7478:Pkd1l1	UTSW	11	8,879,441 (GRCm39)	missense
R7485:Pkd1l1	UTSW	11	8,915,148 (GRCm39)	missense
R7490:Pkd1l1	UTSW	11	8,866,265 (GRCm39)	missense
R7644:Pkd1l1	UTSW	11	8,825,758 (GRCm39)	missense
R7647:Pkd1l1	UTSW	11	8,897,296 (GRCm39)	missense
R7676:Pkd1l1	UTSW	11	8,912,708 (GRCm39)	missense
R7687:Pkd1l1	UTSW	11	8,804,390 (GRCm39)	missense
R7699:Pkd1l1	UTSW	11	8,915,142 (GRCm39)	missense
R7922:Pkd1l1	UTSW	11	8,859,857 (GRCm39)	missense
R7922:Pkd1l1	UTSW	11	8,799,013 (GRCm39)	missense
R7980:Pkd1l1	UTSW	11	8,804,375 (GRCm39)	missense	probably damaging	1.00
R7993:Pkd1l1	UTSW	11	8,895,262 (GRCm39)	missense
R8052:Pkd1l1	UTSW	11	8,897,315 (GRCm39)	missense
R8125:Pkd1l1	UTSW	11	8,897,241 (GRCm39)	missense	probably damaging	1.00
R8420:Pkd1l1	UTSW	11	8,820,277 (GRCm39)	nonsense	probably null
R8675:Pkd1l1	UTSW	11	8,798,916 (GRCm39)	critical splice donor site	probably null
R8683:Pkd1l1	UTSW	11	8,821,805 (GRCm39)	missense
R8709:Pkd1l1	UTSW	11	8,805,567 (GRCm39)	missense
R8711:Pkd1l1	UTSW	11	8,815,550 (GRCm39)	missense
R8725:Pkd1l1	UTSW	11	8,911,482 (GRCm39)	missense
R8733:Pkd1l1	UTSW	11	8,883,657 (GRCm39)	missense
R8822:Pkd1l1	UTSW	11	8,806,312 (GRCm39)	missense
R8871:Pkd1l1	UTSW	11	8,900,503 (GRCm39)	missense
R9009:Pkd1l1	UTSW	11	8,881,552 (GRCm39)	missense
R9099:Pkd1l1	UTSW	11	8,922,986 (GRCm39)	missense
R9119:Pkd1l1	UTSW	11	8,829,107 (GRCm39)	missense
R9150:Pkd1l1	UTSW	11	8,786,256 (GRCm39)	missense
R9314:Pkd1l1	UTSW	11	8,829,153 (GRCm39)	missense
R9341:Pkd1l1	UTSW	11	8,911,305 (GRCm39)	missense
R9341:Pkd1l1	UTSW	11	8,786,399 (GRCm39)	missense
R9343:Pkd1l1	UTSW	11	8,911,305 (GRCm39)	missense
R9343:Pkd1l1	UTSW	11	8,786,399 (GRCm39)	missense
R9392:Pkd1l1	UTSW	11	8,794,567 (GRCm39)	missense
R9424:Pkd1l1	UTSW	11	8,820,091 (GRCm39)	missense
R9496:Pkd1l1	UTSW	11	8,783,773 (GRCm39)	critical splice donor site	probably null
R9504:Pkd1l1	UTSW	11	8,815,631 (GRCm39)	missense
R9563:Pkd1l1	UTSW	11	8,815,502 (GRCm39)	missense
R9570:Pkd1l1	UTSW	11	8,840,697 (GRCm39)	missense
R9585:Pkd1l1	UTSW	11	8,804,390 (GRCm39)	missense
R9618:Pkd1l1	UTSW	11	8,911,420 (GRCm39)	missense
R9709:Pkd1l1	UTSW	11	8,799,016 (GRCm39)	missense	probably damaging	0.98
R9741:Pkd1l1	UTSW	11	8,897,224 (GRCm39)	missense
R9801:Pkd1l1	UTSW	11	8,908,964 (GRCm39)	nonsense	probably null
X0024:Pkd1l1	UTSW	11	8,900,413 (GRCm39)	missense	probably benign	0.01
X0063:Pkd1l1	UTSW	11	8,879,430 (GRCm39)	missense	probably damaging	0.96
X0065:Pkd1l1	UTSW	11	8,859,921 (GRCm39)	missense	probably benign	0.10
Z1176:Pkd1l1	UTSW	11	8,776,801 (GRCm39)	missense
Z1177:Pkd1l1	UTSW	11	8,895,208 (GRCm39)	missense

Predicted Primers

PCR Primer
(F):5'- AAAGAGCTGTTCCGGAAGCC -3'
(R):5'- CCAGTGACTCTTGTACTGCAG -3'

Sequencing Primer
(F):5'- TTCCGGAAGCCACGTGAAC -3'
(R):5'- TGTGAGCACCATAGCCTTAC -3'

Posted On

2018-08-01