Mutagenetix > Incidental Mutation

Incidental Mutation 'R6751:Chd7'

530757

Institutional Source

Beutler Lab

Gene Symbol

Chd7

Ensembl Gene

ENSMUSG00000041235

Gene Name

chromodomain helicase DNA binding protein 7

Synonyms

Whi, Dz, Cyn, GENA 47, Cycn, Lda, Flo, Obt, Edy, A730019I05Rik, Todo, GENA 60, WBE1, Gena 52, Mt

MMRRC Submission

044868-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.952) question?

Stock #

R6751 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

8690406-8867659 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 8833866 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Histidine at position 1207 (Y1207H)

Ref Sequence

ENSEMBL: ENSMUSP00000059079 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039267] [ENSMUST00000051558] [ENSMUST00000170391]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000039267
AA Change: Y1207H

PolyPhen 2 Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000043903
Gene: ENSMUSG00000041235
AA Change: Y1207H

Domain	Start	End	E-Value	Type
low complexity region	11	28	N/A	INTRINSIC
low complexity region	48	59	N/A	INTRINSIC
low complexity region	107	129	N/A	INTRINSIC
low complexity region	152	178	N/A	INTRINSIC
low complexity region	194	206	N/A	INTRINSIC
low complexity region	385	400	N/A	INTRINSIC
low complexity region	491	504	N/A	INTRINSIC
low complexity region	512	535	N/A	INTRINSIC
low complexity region	585	595	N/A	INTRINSIC
low complexity region	632	696	N/A	INTRINSIC
low complexity region	721	733	N/A	INTRINSIC
low complexity region	735	748	N/A	INTRINSIC
low complexity region	759	768	N/A	INTRINSIC
CHROMO	789	854	2.54e-9	SMART
CHROMO	870	927	2.94e-5	SMART
low complexity region	928	939	N/A	INTRINSIC
DEXDc	954	1155	9.64e-38	SMART
HELICc	1310	1394	1.67e-23	SMART
Blast:DEXDc	1608	1653	8e-16	BLAST
low complexity region	1728	1739	N/A	INTRINSIC
internal_repeat_2	1774	1825	1.31e-5	PROSPERO
low complexity region	1831	1846	N/A	INTRINSIC
low complexity region	1898	1906	N/A	INTRINSIC
low complexity region	1929	1947	N/A	INTRINSIC
SANT	1952	2011	9.31e-1	SMART
internal_repeat_2	2079	2126	1.31e-5	PROSPERO
low complexity region	2173	2195	N/A	INTRINSIC
low complexity region	2218	2244	N/A	INTRINSIC
low complexity region	2387	2407	N/A	INTRINSIC
low complexity region	2437	2452	N/A	INTRINSIC
BRK	2553	2602	6.57e-23	SMART
BRK	2631	2675	3.77e-23	SMART
low complexity region	2715	2725	N/A	INTRINSIC
low complexity region	2746	2758	N/A	INTRINSIC
low complexity region	2769	2778	N/A	INTRINSIC
low complexity region	2785	2796	N/A	INTRINSIC
low complexity region	2810	2821	N/A	INTRINSIC
low complexity region	2897	2916	N/A	INTRINSIC
low complexity region	2967	2980	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000051558
AA Change: Y1207H

PolyPhen 2 Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000059079
Gene: ENSMUSG00000041235
AA Change: Y1207H

Domain	Start	End	E-Value	Type
low complexity region	11	28	N/A	INTRINSIC
low complexity region	48	59	N/A	INTRINSIC
low complexity region	107	129	N/A	INTRINSIC
low complexity region	152	178	N/A	INTRINSIC
low complexity region	194	206	N/A	INTRINSIC
low complexity region	385	400	N/A	INTRINSIC
low complexity region	491	504	N/A	INTRINSIC
low complexity region	512	535	N/A	INTRINSIC
low complexity region	585	595	N/A	INTRINSIC
low complexity region	632	696	N/A	INTRINSIC
low complexity region	721	733	N/A	INTRINSIC
low complexity region	735	748	N/A	INTRINSIC
low complexity region	759	768	N/A	INTRINSIC
CHROMO	789	854	2.54e-9	SMART
CHROMO	870	927	2.94e-5	SMART
low complexity region	928	939	N/A	INTRINSIC
DEXDc	954	1155	9.64e-38	SMART
HELICc	1310	1394	1.67e-23	SMART
Blast:DEXDc	1608	1653	8e-16	BLAST
low complexity region	1728	1739	N/A	INTRINSIC
internal_repeat_2	1774	1825	1.31e-5	PROSPERO
low complexity region	1831	1846	N/A	INTRINSIC
low complexity region	1898	1906	N/A	INTRINSIC
low complexity region	1929	1947	N/A	INTRINSIC
SANT	1952	2011	9.31e-1	SMART
internal_repeat_2	2079	2126	1.31e-5	PROSPERO
low complexity region	2173	2195	N/A	INTRINSIC
low complexity region	2218	2244	N/A	INTRINSIC
low complexity region	2387	2407	N/A	INTRINSIC
low complexity region	2437	2452	N/A	INTRINSIC
BRK	2553	2602	6.57e-23	SMART
BRK	2631	2675	3.77e-23	SMART
low complexity region	2715	2725	N/A	INTRINSIC
low complexity region	2746	2758	N/A	INTRINSIC
low complexity region	2769	2778	N/A	INTRINSIC
low complexity region	2785	2796	N/A	INTRINSIC
low complexity region	2810	2821	N/A	INTRINSIC
low complexity region	2897	2916	N/A	INTRINSIC
low complexity region	2967	2980	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000170391

SMART Domains

Protein: ENSMUSP00000127007
Gene: ENSMUSG00000041235

Domain	Start	End	E-Value	Type
low complexity region	11	28	N/A	INTRINSIC
low complexity region	48	59	N/A	INTRINSIC
low complexity region	107	129	N/A	INTRINSIC
low complexity region	152	178	N/A	INTRINSIC
low complexity region	194	206	N/A	INTRINSIC
low complexity region	385	400	N/A	INTRINSIC
low complexity region	491	504	N/A	INTRINSIC
low complexity region	512	535	N/A	INTRINSIC
BRK	586	630	3.77e-23	SMART
low complexity region	670	680	N/A	INTRINSIC
low complexity region	701	713	N/A	INTRINSIC
low complexity region	724	733	N/A	INTRINSIC
low complexity region	740	751	N/A	INTRINSIC
low complexity region	765	776	N/A	INTRINSIC
low complexity region	852	871	N/A	INTRINSIC
low complexity region	922	935	N/A	INTRINSIC

Meta Mutation Damage Score

0.8600

Coding Region Coverage

1x: 99.9%
3x: 99.7%
10x: 98.4%
20x: 95.7%

Validation Efficiency

95% (59/62)

MGI Phenotype

FUNCTION: This gene encodes a protein containing two chromodomains and an ATP-binding helicase domain that functions as a regulator of transcription. Mutations in this gene result in an array of development defects, including inner ear problems. Mice defective for this gene exhibit many of the clinical features of the CHARGE syndrome caused by mutations in the homologous gene in human. [provided by RefSeq, Sep 2015]
PHENOTYPE: Heterozygotes for mutations of this gene exhibit a variety of combinations of hyperactivity, circling, head-bobbing, semicircular canal defects, hearing loss, reduced size, and tail-kink. [provided by MGI curators]

Allele List at MGI

All alleles(32) : Targeted, other(4) Gene trapped(19) Chemically induced(9)

Other mutations in this stock

Total: 63 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110002E22Rik	A	T	3: 137,771,971 (GRCm39)	N387Y	probably damaging	Het
Abhd17a	T	C	10: 80,422,421 (GRCm39)	E87G	probably damaging	Het
Aco1	T	A	4: 40,188,330 (GRCm39)		probably null	Het
Adcy6	T	C	15: 98,494,086 (GRCm39)	N817S	probably benign	Het
Ak8	T	A	2: 28,599,957 (GRCm39)	L63*	probably null	Het
Arhgef28	G	A	13: 98,211,755 (GRCm39)	S76L	probably damaging	Het
Asap1	A	G	15: 63,966,261 (GRCm39)	L891S	possibly damaging	Het
Cacng5	C	A	11: 107,768,379 (GRCm39)	M209I	probably benign	Het
Casr	T	C	16: 36,335,950 (GRCm39)	I120V	probably benign	Het
Ccnq	T	C	11: 78,641,950 (GRCm39)	Y180C	probably damaging	Het
Chrnb2	A	T	3: 89,668,883 (GRCm39)	F144Y	probably damaging	Het
Cyp4a14	T	A	4: 115,348,391 (GRCm39)	H362L	probably damaging	Het
Dnaaf4	A	G	9: 72,869,257 (GRCm39)	T156A	probably benign	Het
Dym	G	A	18: 75,419,718 (GRCm39)	V630M	probably damaging	Het
Dync2i1	A	T	12: 116,177,076 (GRCm39)	V842E	possibly damaging	Het
Dyrk1b	C	A	7: 27,886,134 (GRCm39)	P619Q	probably damaging	Het
Eml5	T	C	12: 98,831,659 (GRCm39)	D433G	probably damaging	Het
Frem2	A	T	3: 53,561,086 (GRCm39)	S1140R	probably damaging	Het
Gabra5	T	C	7: 57,068,082 (GRCm39)	R255G	probably damaging	Het
Galnt17	T	A	5: 131,110,428 (GRCm39)	I304F	probably damaging	Het
Gpc5	A	G	14: 115,607,363 (GRCm39)	S322G	probably benign	Het
Herc1	TCCC	TCC	9: 66,408,470 (GRCm39)		probably null	Het
Hmcn1	T	A	1: 150,610,269 (GRCm39)	N1467Y	probably damaging	Het
Ifna6	T	C	4: 88,745,987 (GRCm39)	L112P	probably damaging	Het
Ifrd1	C	T	12: 40,253,913 (GRCm39)		probably null	Het
Il17f	A	G	1: 20,849,713 (GRCm39)	M17T	probably benign	Het
Itga11	G	A	9: 62,675,866 (GRCm39)	V892I	probably benign	Het
Nckap5l	A	G	15: 99,321,042 (GRCm39)	L1246P	probably damaging	Het
Nlrp4f	A	T	13: 65,342,243 (GRCm39)	H467Q	probably damaging	Het
Ntng2	A	G	2: 29,118,055 (GRCm39)	V131A	possibly damaging	Het
Or51r1	G	A	7: 102,227,706 (GRCm39)	M1I	probably null	Het
Or8b40	T	G	9: 38,027,271 (GRCm39)	Y60D	probably damaging	Het
Or8g37	T	A	9: 39,731,193 (GRCm39)	V86E	probably benign	Het
Or8g55	T	C	9: 39,784,976 (GRCm39)	V135A	probably benign	Het
Osbpl8	T	C	10: 111,110,874 (GRCm39)	Y459H	possibly damaging	Het
Pabpc1	A	T	15: 36,597,778 (GRCm39)	V537D	possibly damaging	Het
Pde4b	A	T	4: 102,459,868 (GRCm39)	M583L	probably damaging	Het
Phlda1	T	C	10: 111,342,555 (GRCm39)	V97A	possibly damaging	Het
Pik3cb	G	T	9: 98,976,574 (GRCm39)	H174Q	probably benign	Het
Plxdc2	A	T	2: 16,552,952 (GRCm39)	I117F	probably benign	Het
Psapl1	C	A	5: 36,362,303 (GRCm39)	C298*	probably null	Het
Rsf1	G	GACGGCGGCT	7: 97,229,116 (GRCm39)		probably benign	Homo
Rtkn2	T	A	10: 67,877,283 (GRCm39)	F448I	probably benign	Het
Scn10a	T	C	9: 119,500,617 (GRCm39)	R221G	probably damaging	Het
Serpina3c	A	G	12: 104,117,759 (GRCm39)	L193P	probably damaging	Het
Sox12	T	C	2: 152,238,678 (GRCm39)	Y314C	probably damaging	Het
Spata31h1	A	G	10: 82,119,331 (GRCm39)	S4560P	probably benign	Het
Sptbn1	T	C	11: 30,067,859 (GRCm39)	E1772G	probably damaging	Het
Supt6	A	G	11: 78,099,775 (GRCm39)	V1570A	probably benign	Het
Synrg	T	C	11: 83,872,251 (GRCm39)	F125S	probably damaging	Het
Tenm4	A	T	7: 96,494,919 (GRCm39)	I1116F	possibly damaging	Het
Tfap2a	T	A	13: 40,882,230 (GRCm39)	N25I	probably damaging	Het
Tfap2d	C	A	1: 19,173,507 (GRCm39)	H10N	possibly damaging	Het
Trpm8	T	C	1: 88,312,428 (GRCm39)	I1103T	possibly damaging	Het
Vmn1r158	C	T	7: 22,489,306 (GRCm39)	C301Y	probably damaging	Het
Vmn2r56	T	C	7: 12,428,719 (GRCm39)	I516V	probably benign	Het
Vmn2r71	G	A	7: 85,269,095 (GRCm39)		probably null	Het
Vnn3	C	T	10: 23,745,523 (GRCm39)	R491C	probably benign	Het
Vps50	A	G	6: 3,600,274 (GRCm39)	Y911C	probably damaging	Het
Zfp772	C	T	7: 7,206,716 (GRCm39)	R325Q	possibly damaging	Het
Zranb3	T	A	1: 127,887,556 (GRCm39)	H957L	probably benign	Het
Zscan20	G	T	4: 128,479,668 (GRCm39)	T941K	probably damaging	Het
Zscan25	T	A	5: 145,227,373 (GRCm39)	F346I	probably damaging	Het

Other mutations in Chd7

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00422:Chd7	APN	4	8,859,106 (GRCm39)	missense	probably damaging	1.00
IGL00510:Chd7	APN	4	8,801,404 (GRCm39)	missense	probably damaging	1.00
IGL00741:Chd7	APN	4	8,839,454 (GRCm39)	missense	probably damaging	1.00
IGL00796:Chd7	APN	4	8,847,271 (GRCm39)	missense	possibly damaging	0.95
IGL00907:Chd7	APN	4	8,840,435 (GRCm39)	missense	probably damaging	0.98
IGL00930:Chd7	APN	4	8,805,181 (GRCm39)	missense	probably damaging	1.00
IGL01542:Chd7	APN	4	8,859,285 (GRCm39)	missense	possibly damaging	0.71
IGL01602:Chd7	APN	4	8,833,834 (GRCm39)	missense	probably damaging	1.00
IGL01605:Chd7	APN	4	8,833,834 (GRCm39)	missense	probably damaging	1.00
IGL01670:Chd7	APN	4	8,827,033 (GRCm39)	missense	probably damaging	0.98
IGL02434:Chd7	APN	4	8,752,145 (GRCm39)	missense	probably benign	0.00
IGL02531:Chd7	APN	4	8,854,134 (GRCm39)	missense	probably damaging	1.00
IGL02626:Chd7	APN	4	8,826,519 (GRCm39)	missense	probably damaging	1.00
IGL02961:Chd7	APN	4	8,751,542 (GRCm39)	missense	probably damaging	1.00
IGL02972:Chd7	APN	4	8,855,174 (GRCm39)	missense	probably benign	0.30
IGL03329:Chd7	APN	4	8,841,108 (GRCm39)	missense	probably damaging	1.00
Fili	UTSW	4	8,839,523 (GRCm39)	missense	probably damaging	1.00
D4043:Chd7	UTSW	4	8,862,650 (GRCm39)	missense	probably damaging	1.00
IGL02991:Chd7	UTSW	4	8,828,398 (GRCm39)	missense	possibly damaging	0.91
PIT4466001:Chd7	UTSW	4	8,753,101 (GRCm39)	missense	unknown
PIT4472001:Chd7	UTSW	4	8,753,101 (GRCm39)	missense	unknown
R0157:Chd7	UTSW	4	8,833,759 (GRCm39)	missense	probably damaging	1.00
R0179:Chd7	UTSW	4	8,862,516 (GRCm39)	missense	probably benign	0.22
R0240:Chd7	UTSW	4	8,852,670 (GRCm39)	unclassified	probably benign
R0388:Chd7	UTSW	4	8,854,560 (GRCm39)	missense	probably benign	0.27
R0462:Chd7	UTSW	4	8,850,821 (GRCm39)	missense	probably damaging	1.00
R0512:Chd7	UTSW	4	8,805,139 (GRCm39)	intron	probably benign
R0657:Chd7	UTSW	4	8,753,141 (GRCm39)	missense	probably damaging	1.00
R0799:Chd7	UTSW	4	8,801,310 (GRCm39)	intron	probably benign
R0885:Chd7	UTSW	4	8,866,432 (GRCm39)	missense	probably damaging	1.00
R1056:Chd7	UTSW	4	8,822,402 (GRCm39)	missense	possibly damaging	0.50
R1086:Chd7	UTSW	4	8,866,458 (GRCm39)	missense	probably benign	0.04
R1353:Chd7	UTSW	4	8,839,556 (GRCm39)	missense	probably damaging	0.99
R1466:Chd7	UTSW	4	8,840,561 (GRCm39)	splice site	probably null
R1466:Chd7	UTSW	4	8,840,561 (GRCm39)	splice site	probably null
R1605:Chd7	UTSW	4	8,844,675 (GRCm39)	missense	probably damaging	1.00
R1693:Chd7	UTSW	4	8,864,307 (GRCm39)	critical splice donor site	probably null
R1695:Chd7	UTSW	4	8,833,960 (GRCm39)	missense	probably damaging	1.00
R1938:Chd7	UTSW	4	8,847,200 (GRCm39)	missense	probably damaging	1.00
R1964:Chd7	UTSW	4	8,865,978 (GRCm39)	missense	probably damaging	0.96
R2020:Chd7	UTSW	4	8,855,226 (GRCm39)	missense	probably benign	0.00
R2134:Chd7	UTSW	4	8,753,147 (GRCm39)	missense	probably damaging	0.99
R2171:Chd7	UTSW	4	8,752,424 (GRCm39)	missense	probably damaging	1.00
R2271:Chd7	UTSW	4	8,785,532 (GRCm39)	missense	probably damaging	1.00
R2300:Chd7	UTSW	4	8,855,241 (GRCm39)	missense	probably benign	0.02
R2355:Chd7	UTSW	4	8,801,350 (GRCm39)	missense	possibly damaging	0.95
R3153:Chd7	UTSW	4	8,855,174 (GRCm39)	missense	probably benign	0.30
R3430:Chd7	UTSW	4	8,844,517 (GRCm39)	missense	probably damaging	0.99
R3746:Chd7	UTSW	4	8,752,537 (GRCm39)	missense	probably damaging	1.00
R4118:Chd7	UTSW	4	8,865,831 (GRCm39)	missense	probably damaging	1.00
R4119:Chd7	UTSW	4	8,785,658 (GRCm39)	intron	probably benign
R4332:Chd7	UTSW	4	8,854,143 (GRCm39)	missense	probably damaging	1.00
R4402:Chd7	UTSW	4	8,866,353 (GRCm39)	missense	possibly damaging	0.61
R4571:Chd7	UTSW	4	8,866,217 (GRCm39)	missense	probably benign	0.09
R4722:Chd7	UTSW	4	8,822,445 (GRCm39)	missense	probably damaging	1.00
R4821:Chd7	UTSW	4	8,844,706 (GRCm39)	missense	probably damaging	1.00
R4894:Chd7	UTSW	4	8,838,629 (GRCm39)	missense	probably damaging	0.99
R5205:Chd7	UTSW	4	8,752,509 (GRCm39)	missense	possibly damaging	0.60
R5344:Chd7	UTSW	4	8,844,417 (GRCm39)	missense	probably damaging	1.00
R5484:Chd7	UTSW	4	8,828,258 (GRCm39)	missense	probably damaging	1.00
R5578:Chd7	UTSW	4	8,847,149 (GRCm39)	missense	probably benign	0.09
R5583:Chd7	UTSW	4	8,752,473 (GRCm39)	missense	probably damaging	1.00
R5888:Chd7	UTSW	4	8,866,382 (GRCm39)	missense	probably damaging	0.98
R5905:Chd7	UTSW	4	8,840,553 (GRCm39)	missense	possibly damaging	0.91
R6091:Chd7	UTSW	4	8,751,875 (GRCm39)	missense	probably damaging	0.99
R6126:Chd7	UTSW	4	8,826,482 (GRCm39)	missense	probably damaging	1.00
R6399:Chd7	UTSW	4	8,828,274 (GRCm39)	missense	probably damaging	1.00
R6810:Chd7	UTSW	4	8,839,523 (GRCm39)	missense	probably damaging	1.00
R6868:Chd7	UTSW	4	8,811,501 (GRCm39)	splice site	probably null
R6952:Chd7	UTSW	4	8,856,797 (GRCm39)	missense	probably damaging	1.00
R6986:Chd7	UTSW	4	8,859,285 (GRCm39)	missense	possibly damaging	0.71
R6990:Chd7	UTSW	4	8,844,525 (GRCm39)	missense	probably benign	0.28
R7139:Chd7	UTSW	4	8,865,865 (GRCm39)	missense	probably benign	0.00
R7288:Chd7	UTSW	4	8,847,093 (GRCm39)	missense	possibly damaging	0.92
R7355:Chd7	UTSW	4	8,752,196 (GRCm39)	missense	unknown
R7452:Chd7	UTSW	4	8,854,731 (GRCm39)	missense	probably benign	0.03
R7471:Chd7	UTSW	4	8,859,197 (GRCm39)	missense	probably damaging	0.96
R7588:Chd7	UTSW	4	8,864,039 (GRCm39)	missense	probably damaging	1.00
R7711:Chd7	UTSW	4	8,805,234 (GRCm39)	missense	probably benign	0.00
R7744:Chd7	UTSW	4	8,862,485 (GRCm39)	splice site	probably null
R7842:Chd7	UTSW	4	8,854,115 (GRCm39)	missense	probably benign	0.01
R7883:Chd7	UTSW	4	8,826,504 (GRCm39)	missense	probably damaging	1.00
R7934:Chd7	UTSW	4	8,854,121 (GRCm39)	missense	probably benign	0.00
R7983:Chd7	UTSW	4	8,844,609 (GRCm39)	missense	possibly damaging	0.47
R7983:Chd7	UTSW	4	8,752,628 (GRCm39)	missense	unknown
R8022:Chd7	UTSW	4	8,751,605 (GRCm39)	missense	unknown
R8161:Chd7	UTSW	4	8,855,038 (GRCm39)	missense	probably damaging	1.00
R8274:Chd7	UTSW	4	8,839,432 (GRCm39)	missense	probably damaging	1.00
R8278:Chd7	UTSW	4	8,862,485 (GRCm39)	splice site	probably null
R8358:Chd7	UTSW	4	8,839,529 (GRCm39)	missense	probably damaging	1.00
R8464:Chd7	UTSW	4	8,811,465 (GRCm39)	missense	probably benign	0.06
R8483:Chd7	UTSW	4	8,822,412 (GRCm39)	missense	possibly damaging	0.65
R8507:Chd7	UTSW	4	8,858,675 (GRCm39)	missense	probably damaging	1.00
R8535:Chd7	UTSW	4	8,859,211 (GRCm39)	missense	possibly damaging	0.92
R8695:Chd7	UTSW	4	8,850,812 (GRCm39)	missense	probably damaging	1.00
R8700:Chd7	UTSW	4	8,833,892 (GRCm39)	missense	probably damaging	1.00
R8755:Chd7	UTSW	4	8,866,069 (GRCm39)	missense	probably benign	0.31
R8774:Chd7	UTSW	4	8,854,692 (GRCm39)	missense	probably damaging	1.00
R8774-TAIL:Chd7	UTSW	4	8,854,692 (GRCm39)	missense	probably damaging	1.00
R8796:Chd7	UTSW	4	8,838,691 (GRCm39)	missense	probably damaging	1.00
R8992:Chd7	UTSW	4	8,839,589 (GRCm39)	missense	probably damaging	1.00
R9018:Chd7	UTSW	4	8,847,083 (GRCm39)	missense	possibly damaging	0.88
R9122:Chd7	UTSW	4	8,840,510 (GRCm39)	missense	possibly damaging	0.77
R9131:Chd7	UTSW	4	8,785,642 (GRCm39)	missense
R9182:Chd7	UTSW	4	8,838,737 (GRCm39)	missense	probably damaging	1.00
R9227:Chd7	UTSW	4	8,805,272 (GRCm39)	missense	probably benign	0.03
R9254:Chd7	UTSW	4	8,752,210 (GRCm39)	missense	unknown
R9379:Chd7	UTSW	4	8,752,210 (GRCm39)	missense	unknown
R9388:Chd7	UTSW	4	8,865,756 (GRCm39)	missense	possibly damaging	0.89
R9455:Chd7	UTSW	4	8,752,061 (GRCm39)	missense	unknown
R9531:Chd7	UTSW	4	8,858,489 (GRCm39)	missense
R9577:Chd7	UTSW	4	8,752,964 (GRCm39)	missense	unknown
R9634:Chd7	UTSW	4	8,832,499 (GRCm39)	missense	probably damaging	1.00
Z1176:Chd7	UTSW	4	8,844,313 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CCAGGATGTTTTAACACGCAAG -3'
(R):5'- TGCTTTCAGAGAGCACTGGC -3'

Sequencing Primer
(F):5'- ACGCCTGAAAGAGGATGT -3'
(R):5'- TCAGCAACCACAGACGGGG -3'

Posted On

2018-08-01