Incidental Mutation 'R6752:Olfr1468-ps1'
ID 530864
Institutional Source Beutler Lab
Gene Symbol Olfr1468-ps1
Ensembl Gene
Gene Name olfactory receptor 1468, pseudogene 1
Synonyms GA_x6K02T2RE5P-3706029-3706953, MOR202-21
MMRRC Submission
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.156) question?
Stock # R6752 (G1)
Quality Score 225.009
Status Validated
Chromosome 19
Chromosomal Location 13374964-13375885 bp(+) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) T to A at 13375526 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Leucine to Histidine at position 188 (L188H)
Ref Sequence ENSEMBL: ENSMUSP00000146788 (fasta)
AlphaFold no structure available at present
Predicted Effect unknown
Transcript: ENSMUST00000207287
AA Change: L188H
Coding Region Coverage
  • 1x: 99.9%
  • 3x: 99.6%
  • 10x: 98.2%
  • 20x: 94.8%
Validation Efficiency 98% (55/56)
Allele List at MGI
Other mutations in this stock
Total: 57 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acaca T C 11: 84,195,483 L45S probably benign Het
Agbl2 G A 2: 90,803,074 C518Y probably damaging Het
Akt3 A T 1: 177,050,190 Y337* probably null Het
Aox1 T C 1: 58,047,239 I101T probably benign Het
Arhgap23 T C 11: 97,452,248 F241S probably damaging Het
Asmt A G X: 170,676,361 M202V probably benign Het
Atp6v0a2 A G 5: 124,641,514 E189G probably damaging Het
Birc3 G A 9: 7,857,344 A376V probably benign Het
Ccbe1 C T 18: 66,076,307 probably null Het
Chst2 C A 9: 95,404,749 E515* probably null Het
Col12a1 A T 9: 79,633,424 N2426K possibly damaging Het
Dmrt2 A G 19: 25,678,342 N435S probably damaging Het
Dnah14 A G 1: 181,593,452 K123E probably benign Het
Dock4 T A 12: 40,820,617 L1452Q probably damaging Het
Galnt7 G A 8: 57,652,951 R10C probably damaging Het
Gm16506 A G 14: 43,727,419 I22T unknown Het
H2-Q6 A G 17: 35,428,127 T292A probably damaging Het
Ifne A G 4: 88,880,082 M33T probably benign Het
Igf2r G A 17: 12,714,944 R808W probably damaging Het
Igfbp5 T C 1: 72,863,909 E169G probably damaging Het
Inppl1 G A 7: 101,832,542 R198* probably null Het
Irgm1 T C 11: 48,866,463 T174A probably damaging Het
Itih3 C T 14: 30,923,489 G21S possibly damaging Het
Klra4 G T 6: 130,062,028 Q134K probably benign Het
Mfsd1 T A 3: 67,596,603 Y309* probably null Het
Mrps10 A G 17: 47,377,815 N162S probably damaging Het
Mtmr14 T C 6: 113,240,397 F90S probably damaging Het
Myh15 A G 16: 49,182,927 D1783G probably damaging Het
Myo3b A G 2: 70,289,512 E972G probably damaging Het
Myt1 G T 2: 181,801,082 V455F probably damaging Het
Nbea T A 3: 55,968,309 T1647S probably benign Het
Nbea A T 3: 56,037,219 S575T probably benign Het
Ntn4 A G 10: 93,734,175 N466S probably benign Het
Olfr1113 A G 2: 87,213,044 M51V probably benign Het
Olfr197 T A 16: 59,186,331 N51Y probably damaging Het
Pcdhgb4 T A 18: 37,720,651 I33N probably damaging Het
Pi4ka A G 16: 17,376,982 L184P possibly damaging Het
Pom121l2 T G 13: 21,981,769 F70C probably damaging Het
Psmb5 T C 14: 54,616,755 T89A probably benign Het
Rab11fip2 T C 19: 59,907,043 D471G probably damaging Het
Rnh1 A G 7: 141,163,441 V207A probably benign Het
Sh3tc2 C A 18: 61,961,037 T49N probably benign Het
Skint4 T C 4: 112,119,863 M158T possibly damaging Het
Skint7 T A 4: 111,980,266 H80Q probably benign Het
Smg1 A G 7: 118,163,316 probably benign Het
Sostdc1 T C 12: 36,314,412 V40A probably benign Het
Sptlc1 C A 13: 53,335,358 K437N possibly damaging Het
Stat2 T C 10: 128,283,753 F503L probably damaging Het
Syt16 A T 12: 74,229,213 probably null Het
Tspyl1 T C 10: 34,282,587 S103P probably benign Het
Ube4a A T 9: 44,925,948 S1053R probably damaging Het
Vipr1 A G 9: 121,653,893 N58S probably damaging Het
Zfp184 C A 13: 21,959,408 A428E probably damaging Het
Zfp292 A C 4: 34,808,593 F1484V possibly damaging Het
Zfp599 G A 9: 22,249,544 H442Y probably damaging Het
Zfp944 G A 17: 22,339,519 T249I probably benign Het
Zkscan14 T A 5: 145,195,506 H405L probably damaging Het
Other mutations in Olfr1468-ps1
AlleleSourceChrCoordTypePredicted EffectPPH Score
R6046:Olfr1468-ps1 UTSW 19 13375334 missense probably benign 0.16
R6141:Olfr1468-ps1 UTSW 19 13375283 missense probably benign 0.03
R6315:Olfr1468-ps1 UTSW 19 13375405 missense unknown
R6587:Olfr1468-ps1 UTSW 19 13375613 missense unknown
R6967:Olfr1468-ps1 UTSW 19 13375451 missense unknown
R7045:Olfr1468-ps1 UTSW 19 13374972 missense probably damaging 1.00
R7182:Olfr1468-ps1 UTSW 19 13375844 missense unknown
R7698:Olfr1468-ps1 UTSW 19 13375040 missense probably damaging 1.00
R7950:Olfr1468-ps1 UTSW 19 13375067 missense possibly damaging 0.78
R8673:Olfr1468-ps1 UTSW 19 13375217 missense probably benign 0.05
R8970:Olfr1468-ps1 UTSW 19 13375753 missense unknown
R9134:Olfr1468-ps1 UTSW 19 13375249 missense probably damaging 0.99
R9269:Olfr1468-ps1 UTSW 19 13375640 missense unknown
R9347:Olfr1468-ps1 UTSW 19 13375189 missense possibly damaging 0.88
Predicted Primers PCR Primer
(F):5'- ATGCAGCAGTGTGTAAGCC -3'
(R):5'- ATGATCGTCCCGTAGAAAATGG -3'

Sequencing Primer
(F):5'- GCAGCAGTGTGTAAGCCACTAC -3'
(R):5'- TCGTCCCGTAGAAAATGGACACTG -3'
Posted On 2018-08-01